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Women in computing in Saudi Arabia

NSF Scholarships in Science, Technology, Engineering, and Mathematics AND Program Evaluation

Alghamdi F, Brandsma GJ, Schillemans T.
GSID: 0sJ1LeZT9d8J
F Alghamdi - womENcourage 2016, September 12–13, Linz, Austria, 2016 - diva-portal.org

Women are generally under-represented in tertiary computer science education in most countries around the world, especially in the West. The most recent report of the National Science Foundation in 2014 shows that only 14% of woman study CS in...

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Alghamdi, F. (2016). Women in computing in Saudi Arabia. In womENcourage 2016, September 12–13, Linz, Austria (pp. 1-3).
Alghamdi, Fayiq. "Women in computing in Saudi Arabia." womENcourage 2016, September 12–13, Linz, Austria. 2016.
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Sex impacts Th1 cells, Tregs, and DCs in both intestinal and systemic immunity in a mouse strain and location-dependent manner.

Biology of sex differences

Elderman M, van Beek A, Brandsma E, de Haan B, Savelkoul H, de Vos P, Faas M.
PMID: 27051505
Biol Sex Differ. 2016 Apr 05;7:21. doi: 10.1186/s13293-016-0075-9. eCollection 2016.

BACKGROUND: Males and females have a different predisposition for the development of intestinal disorders, like inflammatory bowel disease (IBD). We hypothesized that sex specific differences in intestinal immune responses may underlie this bias. To test this hypothesis, we studied...

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Elderman M, van Beek A, Brandsma E, et al. Sex impacts Th1 cells, Tregs, and DCs in both intestinal and systemic immunity in a mouse strain and location-dependent manner. Biol Sex Differ. 2016;7:21doi: 10.1186/s13293-016-0075-9.
Elderman, M., van Beek, A., Brandsma, E., de Haan, B., Savelkoul, H., de Vos, P., & Faas, M. (2016). Sex impacts Th1 cells, Tregs, and DCs in both intestinal and systemic immunity in a mouse strain and location-dependent manner. Biology of sex differences, 721. https://doi.org/10.1186/s13293-016-0075-9
Elderman, Marlies, et al. "Sex impacts Th1 cells, Tregs, and DCs in both intestinal and systemic immunity in a mouse strain and location-dependent manner." Biology of sex differences vol. 7 (2016): 21. doi: https://doi.org/10.1186/s13293-016-0075-9
Elderman M, van Beek A, Brandsma E, de Haan B, Savelkoul H, de Vos P, Faas M. Sex impacts Th1 cells, Tregs, and DCs in both intestinal and systemic immunity in a mouse strain and location-dependent manner. Biol Sex Differ. 2016 Apr 05;7:21. doi: 10.1186/s13293-016-0075-9. eCollection 2016. PMID: 27051505; PMCID: PMC4820953.
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Determination of ultra-trace levels of priority PBDEs in water samples by isotope dilution GC(ECNI)MS using 81Br-labelled standards.

Analytical and bioanalytical chemistry

González-Gago A, Brandsma SH, Leonards PE, de Boer J, Marchante-Gayón JM, Garcia Alonso JI.
PMID: 21874270
Anal Bioanal Chem. 2011 Nov;401(8):2639-49. doi: 10.1007/s00216-011-5323-6. Epub 2011 Aug 27.

A gas chromatography electron capture negative ionization mass spectrometry (GC(ECNI)MS) procedure for the determination of priority polybrominated diphenyl ethers (PBDEs; congeners 28, 47, 99, 100, 153 and 154) in water samples at regulatory EU levels has been developed. The...

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González-Gago A, Brandsma SH, Leonards PE, et al. Determination of ultra-trace levels of priority PBDEs in water samples by isotope dilution GC(ECNI)MS using 81Br-labelled standards. Anal Bioanal Chem. 2011;401(8):2639-49doi: 10.1007/s00216-011-5323-6.
González-Gago, A., Brandsma, S. H., Leonards, P. E., de Boer, J., Marchante-Gayón, J. M., & Garcia Alonso, J. I. (2011). Determination of ultra-trace levels of priority PBDEs in water samples by isotope dilution GC(ECNI)MS using 81Br-labelled standards. Analytical and bioanalytical chemistry, 401(8), 2639-49. https://doi.org/10.1007/s00216-011-5323-6
González-Gago, Adriana, et al. "Determination of ultra-trace levels of priority PBDEs in water samples by isotope dilution GC(ECNI)MS using 81Br-labelled standards." Analytical and bioanalytical chemistry vol. 401,8 (2011): 2639-49. doi: https://doi.org/10.1007/s00216-011-5323-6
González-Gago A, Brandsma SH, Leonards PE, de Boer J, Marchante-Gayón JM, Garcia Alonso JI. Determination of ultra-trace levels of priority PBDEs in water samples by isotope dilution GC(ECNI)MS using 81Br-labelled standards. Anal Bioanal Chem. 2011 Nov;401(8):2639-49. doi: 10.1007/s00216-011-5323-6. Epub 2011 Aug 27. PMID: 21874270.
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The Burke-Fahn-Marsden Dystonia Rating Scale is Age-Dependent in Healthy Children.

Movement disorders clinical practice

Kuiper MJ, Vrijenhoek L, Brandsma R, Lunsing RJ, Burger H, Eggink H, Peall KJ, Contarino MF, Speelman JD, Tijssen MAJ, Sival DA.
PMID: 30838251
Mov Disord Clin Pract. 2016 May 03;3(6):580-586. doi: 10.1002/mdc3.12339. eCollection 2016.

BACKGROUND: The Burke-Fahn-Marsden Dystonia Rating Scale is a universally applied instrument for the quantitative assessment of dystonia in both children and adults. However, immature movements by healthy young children may also show "dystonic characteristics" as a consequence of physiologically...

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Kuiper MJ, Vrijenhoek L, Brandsma R, et al. The Burke-Fahn-Marsden Dystonia Rating Scale is Age-Dependent in Healthy Children. Mov Disord Clin Pract. 2016;3(6):580-586doi: 10.1002/mdc3.12339.
Kuiper, M. J., Vrijenhoek, L., Brandsma, R., Lunsing, R. J., Burger, H., Eggink, H., Peall, K. J., Contarino, M. F., Speelman, J. D., Tijssen, M. A. J., & Sival, D. A. (2016). The Burke-Fahn-Marsden Dystonia Rating Scale is Age-Dependent in Healthy Children. Movement disorders clinical practice, 3(6), 580-586. https://doi.org/10.1002/mdc3.12339
Kuiper, Marieke Johanna, et al. "The Burke-Fahn-Marsden Dystonia Rating Scale is Age-Dependent in Healthy Children." Movement disorders clinical practice vol. 3,6 (2016): 580-586. doi: https://doi.org/10.1002/mdc3.12339
Kuiper MJ, Vrijenhoek L, Brandsma R, Lunsing RJ, Burger H, Eggink H, Peall KJ, Contarino MF, Speelman JD, Tijssen MAJ, Sival DA. The Burke-Fahn-Marsden Dystonia Rating Scale is Age-Dependent in Healthy Children. Mov Disord Clin Pract. 2016 May 03;3(6):580-586. doi: 10.1002/mdc3.12339. eCollection 2016. PMID: 30838251; PMCID: PMC6353340.
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Unmet needs and recommendations to improve meningioma care through patient, partner, and health care provider input: a mixed-method study.

Neuro-oncology practice

Zamanipoor Najafabadi AH, van de Mortel JPM, Lobatto DJ, Brandsma DR, Peul WC, Biermasz N, Taphoorn MJB, Dirven L, van Furth WR.
PMID: 32617172
Neurooncol Pract. 2020 Mar;7(2):239-248. doi: 10.1093/nop/npz055. Epub 2019 Nov 02.

BACKGROUND: It has been suggested that lack of ongoing registration of patient-centered outcomes has resulted in existing care trajectories that have not been optimized for sequelae experienced by meningioma patients. This study aimed to evaluate the structure of current...

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Zamanipoor Najafabadi AH, van de Mortel JPM, Lobatto DJ, et al. Unmet needs and recommendations to improve meningioma care through patient, partner, and health care provider input: a mixed-method study. Neurooncol Pract. 2019;7(2):239-248doi: 10.1093/nop/npz055.
Zamanipoor Najafabadi, A. H., van de Mortel, J. P. M., Lobatto, D. J., Brandsma, D. R., Peul, W. C., Biermasz, N., Taphoorn, M. J. B., Dirven, L., & van Furth, W. R. (2020). Unmet needs and recommendations to improve meningioma care through patient, partner, and health care provider input: a mixed-method study. Neuro-oncology practice, 7(2), 239-248. https://doi.org/10.1093/nop/npz055
Zamanipoor Najafabadi, Amir H, et al. "Unmet needs and recommendations to improve meningioma care through patient, partner, and health care provider input: a mixed-method study." Neuro-oncology practice vol. 7,2 (2020): 239-248. doi: https://doi.org/10.1093/nop/npz055
Zamanipoor Najafabadi AH, van de Mortel JPM, Lobatto DJ, Brandsma DR, Peul WC, Biermasz N, Taphoorn MJB, Dirven L, van Furth WR. Unmet needs and recommendations to improve meningioma care through patient, partner, and health care provider input: a mixed-method study. Neurooncol Pract. 2020 Mar;7(2):239-248. doi: 10.1093/nop/npz055. Epub 2019 Nov 02. PMID: 32617172; PMCID: PMC7318860.
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On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation.

Cancers

van den Tempel N, Zelensky AN, Odijk H, Laffeber C, Schmidt CK, Brandsma I, Demmers J, Krawczyk PM, Kanaar R.
PMID: 30650591
Cancers (Basel). 2019 Jan 15;11(1). doi: 10.3390/cancers11010097.

The DNA damage response (DDR) is a designation for a number of pathways that protects our DNA from various damaging agents. In normal cells, the DDR is extremely important for maintaining genome integrity, but in cancer cells these mechanisms...

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van den Tempel N, Zelensky AN, Odijk H, et al. On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation. Cancers (Basel). 2019;11(1)doi: 10.3390/cancers11010097.
van den Tempel, N., Zelensky, A. N., Odijk, H., Laffeber, C., Schmidt, C. K., Brandsma, I., Demmers, J., Krawczyk, P. M., & Kanaar, R. (2019). On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation. Cancers, 11(1), . https://doi.org/10.3390/cancers11010097
van den Tempel, Nathalie, et al. "On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation." Cancers vol. 11,1 (2019). doi: https://doi.org/10.3390/cancers11010097
van den Tempel N, Zelensky AN, Odijk H, Laffeber C, Schmidt CK, Brandsma I, Demmers J, Krawczyk PM, Kanaar R. On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation. Cancers (Basel). 2019 Jan 15;11(1). doi: 10.3390/cancers11010097. PMID: 30650591; PMCID: PMC6356811.
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Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats.

Toxicological sciences : an official journal of the Society of Toxicology

Mesnage R, Ibragim M, Mandrioli D, Falcioni L, Tibaldi E, Belpoggi F, Brandsma I, Bourne E, Savage E, Mein CA, Antoniou MN.
PMID: 34850229
Toxicol Sci. 2021 Nov 29; doi: 10.1093/toxsci/kfab143. Epub 2021 Nov 29.

Whether glyphosate-based herbicides (GBHs) are more potent than glyphosate alone at activating cellular mechanisms, which drive carcinogenesis remains controversial. As GBHs are more cytotoxic that glyphosate, we reasoned they may also be more capable of activating carcinogenic pathways. We...

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Mesnage R, Ibragim M, Mandrioli D, et al. Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats. Toxicol Sci. 2021;doi: 10.1093/toxsci/kfab143.
Mesnage, R., Ibragim, M., Mandrioli, D., Falcioni, L., Tibaldi, E., Belpoggi, F., Brandsma, I., Bourne, E., Savage, E., Mein, C. A., & Antoniou, M. N. (2021). Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats. Toxicological sciences : an official journal of the Society of Toxicology, . https://doi.org/10.1093/toxsci/kfab143
Mesnage, Robin, et al. "Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats." Toxicological sciences : an official journal of the Society of Toxicology vol. (2021). doi: https://doi.org/10.1093/toxsci/kfab143
Mesnage R, Ibragim M, Mandrioli D, Falcioni L, Tibaldi E, Belpoggi F, Brandsma I, Bourne E, Savage E, Mein CA, Antoniou MN. Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats. Toxicol Sci. 2021 Nov 29; doi: 10.1093/toxsci/kfab143. Epub 2021 Nov 29. PMID: 34850229.
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Plasmodium early transcribed membrane proteins appear tailored to the host range of malaria parasites.

International journal for parasitology

Brandsma AM, Hilmer C, Rauch M, Matuschewski K, Montagna GN.
PMID: 34715088
Int J Parasitol. 2021 Oct 26; doi: 10.1016/j.ijpara.2021.08.005. Epub 2021 Oct 26.

Early transcribed membrane proteins form a unique protein family in malaria parasites. These molecules are expressed during Plasmodium intracellular phases and inserted at the parasite parasitophorus vacuole membrane, which constitutes the host-parasite interface. Upregulated in infectious sporozoites 4 (UIS4)...

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Brandsma AM, Hilmer C, Rauch M, et al. Plasmodium early transcribed membrane proteins appear tailored to the host range of malaria parasites. Int J Parasitol. 2021;doi: 10.1016/j.ijpara.2021.08.005.
Brandsma, A. M., Hilmer, C., Rauch, M., Matuschewski, K., & Montagna, G. N. (2021). Plasmodium early transcribed membrane proteins appear tailored to the host range of malaria parasites. International journal for parasitology, . https://doi.org/10.1016/j.ijpara.2021.08.005
Brandsma, Arianne M, et al. "Plasmodium early transcribed membrane proteins appear tailored to the host range of malaria parasites." International journal for parasitology vol. (2021). doi: https://doi.org/10.1016/j.ijpara.2021.08.005
Brandsma AM, Hilmer C, Rauch M, Matuschewski K, Montagna GN. Plasmodium early transcribed membrane proteins appear tailored to the host range of malaria parasites. Int J Parasitol. 2021 Oct 26; doi: 10.1016/j.ijpara.2021.08.005. Epub 2021 Oct 26. PMID: 34715088.
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A tiered approach to investigate the inhalation toxicity of cobalt substances. Tier 2 b: Reactive cobalt substances induce oxidative stress in ToxTracker and activate hypoxia target genes.

Regulatory toxicology and pharmacology : RTP

Derr R, Moelijker N, Hendriks G, Brandsma I.
PMID: 35038485
Regul Toxicol Pharmacol. 2022 Jan 14;105120. doi: 10.1016/j.yrtph.2022.105120. Epub 2022 Jan 14.

Cobalt metal and cobalt sulfate are carcinogenic in rodents following inhalation exposure. The pre-carcinogenic effects associated with exposure to these cobalt substances include oxidative stress and genotoxicity. Some, but not all, cobalt substances induce in vitro clastogenicity or an...

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Derr R, Moelijker N, Hendriks G, et al. A tiered approach to investigate the inhalation toxicity of cobalt substances. Tier 2 b: Reactive cobalt substances induce oxidative stress in ToxTracker and activate hypoxia target genes. Regul Toxicol Pharmacol. 2022;105120doi: 10.1016/j.yrtph.2022.105120.
Derr, R., Moelijker, N., Hendriks, G., & Brandsma, I. (2022). A tiered approach to investigate the inhalation toxicity of cobalt substances. Tier 2 b: Reactive cobalt substances induce oxidative stress in ToxTracker and activate hypoxia target genes. Regulatory toxicology and pharmacology : RTP, 105120. https://doi.org/10.1016/j.yrtph.2022.105120
Derr, Remco, et al. "A tiered approach to investigate the inhalation toxicity of cobalt substances. Tier 2 b: Reactive cobalt substances induce oxidative stress in ToxTracker and activate hypoxia target genes." Regulatory toxicology and pharmacology : RTP vol. (2022): 105120. doi: https://doi.org/10.1016/j.yrtph.2022.105120
Derr R, Moelijker N, Hendriks G, Brandsma I. A tiered approach to investigate the inhalation toxicity of cobalt substances. Tier 2 b: Reactive cobalt substances induce oxidative stress in ToxTracker and activate hypoxia target genes. Regul Toxicol Pharmacol. 2022 Jan 14;105120. doi: 10.1016/j.yrtph.2022.105120. Epub 2022 Jan 14. PMID: 35038485.
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MiR-223 is increased in lungs of patients with COPD and modulates cigarette smoke-induced pulmonary inflammation.

American journal of physiology. Lung cellular and molecular physiology

Roffel MP, Maes T, Brandsma CA, van den Berge M, Vanaudenaerde BM, Joos GF, Brusselle GG, Heijink IH, Bracke KR.
PMID: 34668437
Am J Physiol Lung Cell Mol Physiol. 2021 Dec 01;321(6):L1091-L1104. doi: 10.1152/ajplung.00252.2021. Epub 2021 Oct 20.

Since microRNA (miR)-223-3p modulates inflammatory responses and chronic obstructive pulmonary disease (COPD) is associated with amplified pulmonary inflammation, we hypothesized that miR-223-3p plays a role in COPD pathogenesis. Expression of miR-223-3p was measured in lung tissue of two independent...

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Roffel MP, Maes T, Brandsma CA, et al. MiR-223 is increased in lungs of patients with COPD and modulates cigarette smoke-induced pulmonary inflammation. Am J Physiol Lung Cell Mol Physiol. 2021;321(6):L1091-L1104doi: 10.1152/ajplung.00252.2021.
Roffel, M. P., Maes, T., Brandsma, C. A., van den Berge, M., Vanaudenaerde, B. M., Joos, G. F., Brusselle, G. G., Heijink, I. H., & Bracke, K. R. (2021). MiR-223 is increased in lungs of patients with COPD and modulates cigarette smoke-induced pulmonary inflammation. American journal of physiology. Lung cellular and molecular physiology, 321(6), L1091-L1104. https://doi.org/10.1152/ajplung.00252.2021
Roffel, Mirjam P, et al. "MiR-223 is increased in lungs of patients with COPD and modulates cigarette smoke-induced pulmonary inflammation." American journal of physiology. Lung cellular and molecular physiology vol. 321,6 (2021): L1091-L1104. doi: https://doi.org/10.1152/ajplung.00252.2021
Roffel MP, Maes T, Brandsma CA, van den Berge M, Vanaudenaerde BM, Joos GF, Brusselle GG, Heijink IH, Bracke KR. MiR-223 is increased in lungs of patients with COPD and modulates cigarette smoke-induced pulmonary inflammation. Am J Physiol Lung Cell Mol Physiol. 2021 Dec 01;321(6):L1091-L1104. doi: 10.1152/ajplung.00252.2021. Epub 2021 Oct 20. PMID: 34668437.
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D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling.

EBioMedicine

Song S, Liu B, Habibie H, van den Bor J, Smit MJ, Gosens R, Wu X, Brandsma CA, Cool RH, Haisma HJ, Poelarends GJ, Melgert BN.
PMID: 34098338
EBioMedicine. 2021 Jun;68:103412. doi: 10.1016/j.ebiom.2021.103412. Epub 2021 Jun 04.

BACKGROUND: Emphysematous COPD is characterized by aberrant alveolar repair. Macrophage migration inhibitory factor (MIF) contributes to alveolar repair, but for its structural and functional homolog D-dopachrome tautomerase (DDT) this is unknown. MIF mediates its effects through CD74 and/or C-X-C...

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Song S, Liu B, Habibie H, et al. D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling. EBioMedicine. 2021;68:103412doi: 10.1016/j.ebiom.2021.103412.
Song, S., Liu, B., Habibie, H., van den Bor, J., Smit, M. J., Gosens, R., Wu, X., Brandsma, C. A., Cool, R. H., Haisma, H. J., Poelarends, G. J., & Melgert, B. N. (2021). D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling. EBioMedicine, 68103412. https://doi.org/10.1016/j.ebiom.2021.103412
Song, Shanshan, et al. "D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling." EBioMedicine vol. 68 (2021): 103412. doi: https://doi.org/10.1016/j.ebiom.2021.103412
Song S, Liu B, Habibie H, van den Bor J, Smit MJ, Gosens R, Wu X, Brandsma CA, Cool RH, Haisma HJ, Poelarends GJ, Melgert BN. D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling. EBioMedicine. 2021 Jun;68:103412. doi: 10.1016/j.ebiom.2021.103412. Epub 2021 Jun 04. PMID: 34098338; PMCID: PMC8185224.
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Applicability of quantitative oculomotor and SARA assessment in children.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Vogelaar FA, Brandsma R, Maurits NM, Sival DA.
PMID: 34610562
Eur J Paediatr Neurol. 2021 Sep 25;35:56-60. doi: 10.1016/j.ejpn.2021.09.011. Epub 2021 Sep 25.

BACKGROUND: In clinical practice, eye movements can provide an early diagnostic marker for early onset ataxia (EOA). However, quantitative oculomotor assessment is not included in the most frequently used and age-validated ataxia rating scale in children, the Scale for...

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Vogelaar FA, Brandsma R, Maurits NM, et al. Applicability of quantitative oculomotor and SARA assessment in children. Eur J Paediatr Neurol. 2021;35:56-60doi: 10.1016/j.ejpn.2021.09.011.
Vogelaar, F. A., Brandsma, R., Maurits, N. M., & Sival, D. A. (2021). Applicability of quantitative oculomotor and SARA assessment in children. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 3556-60. https://doi.org/10.1016/j.ejpn.2021.09.011
Vogelaar, Francien A, et al. "Applicability of quantitative oculomotor and SARA assessment in children." European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society vol. 35 (2021): 56-60. doi: https://doi.org/10.1016/j.ejpn.2021.09.011
Vogelaar FA, Brandsma R, Maurits NM, Sival DA. Applicability of quantitative oculomotor and SARA assessment in children. Eur J Paediatr Neurol. 2021 Sep 25;35:56-60. doi: 10.1016/j.ejpn.2021.09.011. Epub 2021 Sep 25. PMID: 34610562.
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Showing 1 to 12 of 54 entries