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Showing 1 to 12 of 201 entries
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Germline whole exome sequencing and large-scale replication identifies .

Oncotarget

Dicks E, Song H, Ramus SJ, Oudenhove EV, Tyrer JP, Intermaggio MP, Kar S, Harrington P, Bowtell DD, Group AS, Cicek MS, Cunningham JM, Fridley BL, Alsop J, Jimenez-Linan M, Piskorz A, Goranova T, Kent E, Siddiqui N, Paul J, Crawford R, Poblete S, Lele S, Sucheston-Campbell L, Moysich KB, Sieh W, McGuire V, Lester J, Odunsi K, Whittemore AS, Bogdanova N, Dürst M, Hillemanns P, Karlan BY, Gentry-Maharaj A, Menon U, Tischkowitz M, Levine D, Brenton JD, Dörk T, Goode EL, Gayther SA, Pharoah DPP.
PMID: 28881617
Oncotarget. 2017 Mar 03;8(31):50930-50940. doi: 10.18632/oncotarget.15871. eCollection 2017 Aug 01.

We analyzed whole exome sequencing data in germline DNA from 412 high grade serous ovarian cancer (HGSOC) cases from The Cancer Genome Atlas Project and identified 5,517 genes harboring a predicted deleterious germline coding mutation in at least one...

Design Rules for Fluorocarbon-Free Omniphobic Solvent Barriers in Paper-Based Devices.

ACS applied materials & interfaces

Jahanshahi-Anbuhi S, Pennings K, Leung V, Kannan B, Brennan JD, Filipe CD, Pelton RH.
PMID: 26496157
ACS Appl Mater Interfaces. 2015 Nov 18;7(45):25434-40. doi: 10.1021/acsami.5b08301. Epub 2015 Nov 04.

The utility of hydrophobic wax barriers in paper-based lateral flow and multiwell devices for containment of aqueous solvents was extended to organic solvents and challenging aqueous surfactant solutions by preparation of a three layer barrier, consisting of internal pullulan...

Automatic quantitative analysis of experimental primary and secondary retinal neurodegeneration: implications for optic neuropathies.

Cell death discovery

Davis BM, Guo L, Brenton J, Langley L, Normando EM, Cordeiro MF.
PMID: 27551521
Cell Death Discov. 2016 May 23;2:16031. doi: 10.1038/cddiscovery.2016.31. eCollection 2016.

Secondary neurodegeneration is thought to play an important role in the pathology of neurodegenerative disease, which potential therapies may target. However, the quantitative assessment of the degree of secondary neurodegeneration is difficult. The present study describes a novel algorithm...

Elimination of Dog-Mediated Human Rabies Deaths by 2030: Needs Assessment and Alternatives for Progress Based on Dog Vaccination.

Frontiers in veterinary science

Wallace RM, Undurraga EA, Blanton JD, Cleaton J, Franka R.
PMID: 28239608
Front Vet Sci. 2017 Feb 10;4:9. doi: 10.3389/fvets.2017.00009. eCollection 2017.

BACKGROUND: Rabies imposes a substantial burden to about half of the world population. The World Health Organization (WHO), World Organization for Animal Health, and the Food and Agriculture Organization have set the goal of eliminating dog-mediated human rabies deaths...

Visual and Ocular Manifestations of Alzheimer's Disease and Their Use as Biomarkers for Diagnosis and Progression.

Frontiers in neurology

Javaid FZ, Brenton J, Guo L, Cordeiro MF.
PMID: 27148157
Front Neurol. 2016 Apr 19;7:55. doi: 10.3389/fneur.2016.00055. eCollection 2016.

Alzheimer's disease (AD) is the most common form of dementia affecting the growing aging population today, with prevalence expected to rise over the next 35 years. Clinically, patients exhibit a progressive decline in cognition, memory, and social functioning due...

Administrative Measures for the Control of Scarlet Fever.

California state journal of medicine

Benton JJ.
PMID: 18736138
Cal State J Med. 1914 Jan;12(1):21-2.

No abstract available.

Dermatologic radiotherapy-R.I.p.

California medicine

Brayton JD.
PMID: 18730670
Calif Med. 1972 Jan;116(1):79-80.

No abstract available.

An evaluation of the effectiveness of adaptive histogram equalization for contrast enhancement.

IEEE transactions on medical imaging

Zimmerman JB, Pizer SM, Staab EV, Perry JR, McCartney W, Brenton BC.
PMID: 18230483
IEEE Trans Med Imaging. 1988;7(4):304-12. doi: 10.1109/42.14513.

Adaptive histogram equalization (AHE) and intensity windowing have been compared using psychophysical observer studies. Experienced radiologists were shown clinical CT (computerized tomographic) images of the chest. Into some of the images, appropriate artificial lesions were introduced; the physicians were...

The contribution of other members of the health team to the solution of medical manpower problems: panel discussion.

Bulletin of the New York Academy of Medicine

Lambertsen EC, Rabkin MT, Benton JG, Strauss B.
PMID: 19312957
Bull N Y Acad Med. 1976 Nov;52(9):1153-6.

No abstract available.

Cotrimoxazole-resistant Escherichia coli bacteremia in neutropenic patients at a regional oncology hospital.

The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses

Gregson DB, Matlow AG, Simor AE, Tuffnell PG, Low DE, Feld R, Brunton JE.
PMID: 22451756
Can J Infect Dis. 1992 Jan;3(1):14-8. doi: 10.1155/1992/140845.

In a regional oncology hospital using cotrimoxazole (trimethoprim-sulphamethoxazole) prophylaxis during chemotherapy-induced neutropenia, a single strain of Escherichia coli (indole negative) caused 15 of 27 episodes of Gram-negative rod bacteremia in 1987, and four of 32 such episodes in 1988....

Frontiers in therapeutic development of allopregnanolone for Alzheimer's disease and other neurological disorders.

Frontiers in cellular neuroscience

Irwin RW, Solinsky CM, Brinton RD.
PMID: 25126056
Front Cell Neurosci. 2014 Jul 30;8:203. doi: 10.3389/fncel.2014.00203. eCollection 2014.

Allopregnanolone (Allo), a neurosteroid, has emerged as a promising promoter of endogenous regeneration in brain. In a mouse model of Alzheimer's disease, Allo induced neurogenesis, oligodendrogenesis, white matter generation and cholesterol homeostasis while simultaneously reducing β-amyloid and neuroinflammatory burden....

Oligoclonal bands increase the specificity of MRI criteria to predict multiple sclerosis in children with radiologically isolated syndrome.

Multiple sclerosis journal - experimental, translational and clinical

Makhani N, Lebrun C, Siva A, Narula S, Wassmer E, Brassat D, Brenton JN, Cabre P, Carra Dallière C, de Seze J, Durand Dubief F, Inglese M, Langille M, Mathey G, Neuteboom RF, Pelletier J, Pohl D, Reich DS, Ignacio Rojas J, Shabanova V, Shapiro ED, Stone RT, Tenembaum S, Tintoré M, Uygunoglu U, Vargas W, Venkateswaren S, Vermersch P, Kantarci O, Okuda DT, Pelletier D.
PMID: 30915227
Mult Scler J Exp Transl Clin. 2019 Mar 20;5(1):2055217319836664. doi: 10.1177/2055217319836664. eCollection 2019.

BACKGROUND: Steps towards the development of diagnostic criteria are needed for children with the radiologically isolated syndrome to identify children at risk of clinical demyelination.OBJECTIVES: To evaluate the 2005 and 2016 MAGNIMS magnetic resonance imaging criteria for dissemination in...

Showing 1 to 12 of 201 entries