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Delineating intracellular pharmacokinetics of paclitaxel delivered by PLGA nanoparticles.

Drug delivery and translational research

Li M, Czyszczon EA, Reineke JJ, Brigido M, Borrachero AB.
PMID: 25786375
Drug Deliv Transl Res. 2013 Dec;3(6):551-61. doi: 10.1007/s13346-013-0162-y.

Although many studies have shown that drug delivery and efficacy can be improved by nano-sized drug carriers, we understand little regarding their pharmacokinetics (PK). PK calculations for drugs delivered by carriers are more complex than those for drug-only solutions....

Fermi-LAT observations of the gamma-ray burst GRB 130427A.

Science (New York, N.Y.)

Ackermann M, Ajello M, Asano K, Atwood WB, Axelsson M, Baldini L, Ballet J, Barbiellini G, Baring MG, Bastieri D, Bechtol K, Bellazzini R, Bissaldi E, Bonamente E, Bregeon J, Brigida M, Bruel P, Buehler R, Burgess JM, Buson S, Caliandro GA, Cameron RA, Caraveo PA, Cecchi C, Chaplin V, Charles E, Chekhtman A, Cheung CC, Chiang J, Chiaro G, Ciprini S, Claus R, Cleveland W, Cohen-Tanugi J, Collazzi A, Cominsky LR, Connaughton V, Conrad J, Cutini S, D'Ammando F, de Angelis A, DeKlotz M, de Palma F, Dermer CD, Desiante R, Diekmann A, Di Venere L, Drell PS, Drlica-Wagner A, Favuzzi C, Fegan SJ, Ferrara EC, Finke J, Fitzpatrick G, Focke WB, Franckowiak A, Fukazawa Y, Funk S, Fusco P, Gargano F, Gehrels N, Germani S, Gibby M, Giglietto N, Giles M, Giordano F, Giroletti M, Godfrey G, Granot J, Grenier IA, Grove JE, Gruber D, Guiriec S, Hadasch D, Hanabata Y, Harding AK, Hayashida M, Hays E, Horan D, Hughes RE, Inoue Y, Jogler T, Jóhannesson G, Johnson WN, Kawano T, Knödlseder J, Kocevski D, Kuss M, Lande J, Larsson S, Latronico L, Longo F, Loparco F, Lovellette MN, Lubrano P, Mayer M, Mazziotta MN, McEnery JE, Michelson PF, Mizuno T, Moiseev AA, Monzani ME, Moretti E, Morselli A, Moskalenko IV, Murgia S, Nemmen R, Nuss E, Ohno M, Ohsugi T, Okumura A, Omodei N, Orienti M, Paneque D, Pelassa V, Perkins JS, Pesce-Rollins M, Petrosian V, Piron F, Pivato G, Porter TA, Racusin JL, Rainò S, Rando R, Razzano M, Razzaque S, Reimer A, Reimer O, Ritz S, Roth M, Ryde F, Sartori A, Parkinson PM, Scargle JD, Schulz A, Sgrò C, Siskind EJ, Sonbas E, Spandre G, Spinelli P, Tajima H, Takahashi H, Thayer JG, Thayer JB, Thompson DJ, Tibaldo L, Tinivella M, Torres DF, Tosti G, Troja E, Usher TL, Vandenbroucke J, Vasileiou V, Vianello G, Vitale V, Winer BL, Wood KS, Yamazaki R, Younes G, Yu HF, Zhu SJ, Bhat PN, Briggs MS, Byrne D, Foley S, Goldstein A, Jenke P, Kippen RM, Kouveliotou C, McBreen S, Meegan C, Paciesas WS, Preece R, Rau A, Tierney D, van der Horst AJ, von Kienlin A, Wilson-Hodge C, Xiong S, Cusumano G, La Parola V, Cummings JR.
PMID: 24263133
Science. 2014 Jan 03;343(6166):42-7. doi: 10.1126/science.1242353. Epub 2013 Nov 21.

The observations of the exceptionally bright gamma-ray burst (GRB) 130427A by the Large Area Telescope aboard the Fermi Gamma-ray Space Telescope provide constraints on the nature of these unique astrophysical sources. GRB 130427A had the largest fluence, highest-energy photon...

Reck enables cerebrovascular development by promoting canonical Wnt signaling.

Development (Cambridge, England)

Ulrich F, Carretero-Ortega J, Menéndez J, Narvaez C, Sun B, Lancaster E, Pershad V, Trzaska S, Véliz E, Kamei M, Prendergast A, Kidd KR, Shaw KM, Castranova DA, Pham VN, Lo BD, Martin BL, Raible DW, Weinstein BM, Torres-Vázquez J.
PMID: 26980794
Development. 2016 Mar 15;143(6):1055. doi: 10.1242/dev.136507.

No abstract available.

Reducing the risk of surgical site infection using a multidisciplinary approach: an integrative review.

Journal of multidisciplinary healthcare

Gillespie BM, Kang E, Roberts S, Lin F, Morley N, Finigan T, Homer A, Chaboyer W.
PMID: 26508870
J Multidiscip Healthc. 2015 Oct 13;8:473-87. doi: 10.2147/JMDH.S73565. eCollection 2015.

PURPOSE: To identify and describe the strategies and processes used by multidisciplinary teams of health care professionals to reduce surgical site infections (SSIs).MATERIALS AND METHODS: An integrative review of the research literature was undertaken. Searches were conducted in April...

Office workers' objectively assessed total and prolonged sitting time: Individual-level correlates and worksite variations.

Preventive medicine reports

Hadgraft NT, Healy GN, Owen N, Winkler EA, Lynch BM, Sethi P, Eakin EG, Moodie M, LaMontagne AD, Wiesner G, Willenberg L, Dunstan DW.
PMID: 27413681
Prev Med Rep. 2016 Jun 15;4:184-91. doi: 10.1016/j.pmedr.2016.06.011. eCollection 2016 Dec.

Sedentary behavior is highly prevalent in office-based workplaces; however, few studies have assessed the attributes associated with this health risk factor in the workplace setting. This study aimed to identify the correlates of office workers' objectively-assessed total and prolonged...

Tailoring International Pressure Ulcer Prevention Guidelines for Nigeria: A Knowledge Translation Study Protocol.

Healthcare (Basel, Switzerland)

Ilesanmi RE, Gillespie BM, Adejumo PO, Chaboyer W.
PMID: 27417784
Healthcare (Basel). 2015 Jul 28;3(3):619-29. doi: 10.3390/healthcare3030619.

BACKGROUND: The 2014 International Pressure Ulcer Prevention (PUP) Clinical Practice Guidelines (CPG) provides the most current evidence based strategies to prevent Pressure Ulcer (PU). The evidence upon which these guidelines have been developed has predominantly been generated from research...

The Fermi Gamma-Ray Space Telescope discovers the pulsar in the young galactic supernova remnant CTA 1.

Science (New York, N.Y.)

Abdo AA, Ackermann M, Atwood WB, Baldini L, Ballet J, Barbiellini G, Baring MG, Bastieri D, Baughman BM, Bechtol K, Bellazzini R, Berenji B, Blandford RD, Bloom ED, Bogaert G, Bonamente E, Borgland AW, Bregeon J, Brez A, Brigida M, Bruel P, Burnett TH, Caliandro GA, Cameron RA, Caraveo PA, Carlson P, Casandjian JM, Cecchi C, Charles E, Chekhtman A, Cheung CC, Chiang J, Ciprini S, Claus R, Cohen-Tanugi J, Cominsky LR, Conrad J, Cutini S, Davis DS, Dermer CD, de Angelis A, de Palma F, Digel SW, Dormody M, do Couto E Silva E, Drell PS, Dubois R, Dumora D, Edmonds Y, Farnier C, Focke WB, Fukazawa Y, Funk S, Fusco P, Gargano F, Gasparrini D, Gehrels N, Germani S, Giebels B, Giglietto N, Giordano F, Glanzman T, Godfrey G, Grenier IA, Grondin MH, Grove JE, Guillemot L, Guiriec S, Harding AK, Hartman RC, Hays E, Hughes RE, Jóhannesson G, Johnson AS, Johnson RP, Johnson TJ, Johnson WN, Kamae T, Kanai Y, Kanbach G, Katagiri H, Kawai N, Kerr M, Kishishita T, Kiziltan B, Knödlseder J, Kocian ML, Komin N, Kuehn F, Kuss M, Latronico L, Lemoine-Goumard M, Longo F, Lonjou V, Loparco F, Lott B, Lovellette MN, Lubrano P, Makeev A, Marelli M, Mazziotta MN, McEnery JE, McGlynn S, Meurer C, Michelson PF, Mineo T, Mitthumsiri W, Mizuno T, Moiseev AA, Monte C, Monzani ME, Morselli A, Moskalenko IV, Murgia S, Nakamori T, Nolan PL, Nuss E, Ohno M, Ohsugi T, Okumura A, Omodei N, Orlando E, Ormes JF, Ozaki M, Paneque D, Panetta JH, Parent D, Pelassa V, Pepe M, Pesce-Rollins M, Piano G, Pieri L, Piron F, Porter TA, Rainò S, Rando R, Ray PS, Razzano M, Reimer A, Reimer O, Reposeur T, Ritz S, Rochester LS, Rodriguez AY, Romani RW, Roth M, Ryde F, Sadrozinski HF, Sanchez D, Sander A, Parkinson PM, Schalk TL, Sellerholm A, Sgrò C, Siskind EJ, Smith DA, Smith PD, Spandre G, Spinelli P, Starck JL, Strickman MS, Suson DJ, Tajima H, Takahashi H, Takahashi T, Tanaka T, Thayer JB, Thayer JG, Thompson DJ, Thorsett SE, Tibaldo L, Torres DF, Tosti G, Tramacere A, Usher TL, Van Etten A, Vilchez N, Vitale V, Wang P, Watters K, Winer BL, Wood KS, Yasuda H, Ylinen T, Ziegler M.
PMID: 18927355
Science. 2008 Nov 21;322(5905):1218-21. doi: 10.1126/science.1165572. Epub 2008 Oct 16.

Energetic young pulsars and expanding blast waves [supernova remnants (SNRs)] are the most visible remains after massive stars, ending their lives, explode in core-collapse supernovae. The Fermi Gamma-Ray Space Telescope has unveiled a radio quiet pulsar located near the...

Spectrum of the isotropic diffuse gamma-ray emission derived from first-year Fermi Large Area Telescope data.

Physical review letters

Abdo AA, Ackermann M, Ajello M, Atwood WB, Baldini L, Ballet J, Barbiellini G, Bastieri D, Baughman BM, Bechtol K, Bellazzini R, Berenji B, Blandford RD, Bloom ED, Bonamente E, Borgland AW, Bregeon J, Brez A, Brigida M, Bruel P, Burnett TH, Buson S, Caliandro GA, Cameron RA, Caraveo PA, Casandjian JM, Cavazzuti E, Cecchi C, Celik O, Charles E, Chekhtman A, Cheung CC, Chiang J, Ciprini S, Claus R, Cohen-Tanugi J, Cominsky LR, Conrad J, Cutini S, Dermer CD, de Angelis A, de Palma F, Digel SW, Di Bernardo G, do Couto e Silva E, Drell PS, Drlica-Wagner A, Dubois R, Dumora D, Farnier C, Favuzzi C, Fegan SJ, Focke WB, Fortin P, Frailis M, Fukazawa Y, Funk S, Fusco P, Gaggero D, Gargano F, Gasparrini D, Gehrels N, Germani S, Giebels B, Giglietto N, Giommi P, Giordano F, Glanzman T, Godfrey G, Grenier IA, Grondin MH, Grove JE, Guillemot L, Guiriec S, Gustafsson M, Hanabata Y, Harding AK, Hayashida M, Hughes RE, Itoh R, Jackson MS, Jóhannesson G, Johnson AS, Johnson RP, Johnson TJ, Johnson WN, Kamae T, Katagiri H, Kataoka J, Kawai N, Kerr M, Knödlseder J, Kocian ML, Kuehn F, Kuss M, Lande J, Latronico L, Lemoine-Goumard M, Longo F, Loparco F, Lott B, Lovellette MN, Lubrano P, Madejski GM, Makeev A, Mazziotta MN, McConville W, McEnery JE, Meurer C, Michelson PF, Mitthumsiri W, Mizuno T, Moiseev AA, Monte C, Monzani ME, Morselli A, Moskalenko IV, Murgia S, Nolan PL, Norris JP, Nuss E, Ohsugi T, Omodei N, Orlando E, Ormes JF, Paneque D, Panetta JH, Parent D, Pelassa V, Pepe M, Pesce-Rollins M, Piron F, Porter TA, Rainò S, Rando R, Razzano M, Reimer A, Reimer O, Reposeur T, Ritz S, Rochester LS, Rodriguez AY, Roth M, Ryde F, Sadrozinski HF, Sanchez D, Sander A, Saz Parkinson PM, Scargle JD, Sellerholm A, Sgrò C, Shaw MS, Siskind EJ, Smith DA, Smith PD, Spandre G, Spinelli P, Starck JL, Strickman MS, Strong AW, Suson DJ, Tajima H, Takahashi H, Takahashi T, Tanaka T, Thayer JB, Thayer JG, Thompson DJ, Tibaldo L, Torres DF, Tosti G, Tramacere A, Uchiyama Y, Usher TL, Vasileiou V, Vilchez N, Vitale V, Waite AP, Wang P, Winer BL, Wood KS, Ylinen T, Ziegler M.
PMID: 20366411
Phys Rev Lett. 2010 Mar 12;104(10):101101. doi: 10.1103/PhysRevLett.104.101101. Epub 2010 Mar 08.

We report on the first Fermi Large Area Telescope (LAT) measurements of the so-called "extragalactic" diffuse gamma-ray emission (EGB). This component of the diffuse gamma-ray emission is generally considered to have an isotropic or nearly isotropic distribution on the...

Smoking and breast cancer recurrence after breast conservation therapy.

International journal of breast cancer

Bishop JD, Killelea BK, Chagpar AB, Horowitz NR, Lannin DR.
PMID: 24693439
Int J Breast Cancer. 2014;2014:327081. doi: 10.1155/2014/327081. Epub 2014 Feb 17.

Background. Prior studies have shown earlier recurrence and decreased survival in patients with head and neck cancer who smoked while undergoing radiation therapy. The purpose of the current study was to determine whether smoking status at the time of...

Draft Genome Sequence of FT9, a Novel Bacillus cereus Strain Isolated from a Brazilian Thermal Spring.

Genome announcements

Raiol T, De-Souza MT, Oliveira JV, Silva HS, Orem JC, Cavalcante DA, Almeida NF, Telles GP, Setubal JC, Brigido MM, Torres FA, Stadler PS, Walter ME, Moraes LM.
PMID: 25301660
Genome Announc. 2014 Oct 09;2(5). doi: 10.1128/genomeA.01027-14.

A Bacillus cereus strain, FT9, isolated from a hot spring in the midwest region of Brazil, had its entire genome sequenced.

Building shared situational awareness in surgery through distributed dialog.

Journal of multidisciplinary healthcare

Gillespie BM, Gwinner K, Fairweather N, Chaboyer W.
PMID: 23662066
J Multidiscip Healthc. 2013 Mar 20;6:109-18. doi: 10.2147/JMDH.S40710. Print 2013.

BACKGROUND: Failure to convey time-critical information to team members during surgery diminishes members' perception of the dynamic information relevant to their task, and compromises shared situational awareness. This research reports the dialog around clinical decisions made by team members...

Endoscopic Surveillance in Long-standing Colitis.

Current treatment options in gastroenterology

Boland BS, Shergill A, Kaltenbach T.
PMID: 28803403
Curr Treat Options Gastroenterol. 2017 Sep;15(3):429-439. doi: 10.1007/s11938-017-0141-3.

OPINION STATEMENT: There is a relative increase in the risk of colon cancer in patients with inflammatory bowel disease (IBD) affecting the colon, and endoscopic surveillance is advocated to mitigate this risk. The current standard practice is to survey...

Showing 1 to 12 of 320 entries