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Showing 1 to 12 of 92 entries
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Cisgenic apple trees; development, characterization, and performance.

Frontiers in plant science

Krens FA, Schaart JG, van der Burgh AM, Tinnenbroek-Capel IE, Groenwold R, Kodde LP, Broggini GA, Gessler C, Schouten HJ.
PMID: 25964793
Front Plant Sci. 2015 Apr 27;6:286. doi: 10.3389/fpls.2015.00286. eCollection 2015.

Two methods were developed for the generation of cisgenic apples. Both have been successfully applied producing trees. The first method avoids the use of any foreign selectable marker genes; only the gene-of-interest is integrated between the T-DNA border sequences....

Fluoxetine effects on molecular, cellular and behavioral endophenotypes of depression are driven by the living environment.

Molecular psychiatry

Alboni S, van Dijk RM, Poggini S, Milior G, Perrotta M, Drenth T, Brunello N, Wolfer DP, Limatola C, Amrein I, Cirulli F, Maggi L, Branchi I.
PMID: 26598067
Mol Psychiatry. 2017 Apr;22(4):635. doi: 10.1038/mp.2015.191. Epub 2015 Nov 24.

No abstract available.

Regioselectivity on the palladium-catalyzed intramolecular cyclization of indole derivatives.

The Journal of organic chemistry

Abbiati G, Beccalli EM, Broggini G, Zoni C.
PMID: 14510534
J Org Chem. 2003 Oct 03;68(20):7625-8. doi: 10.1021/jo034636v.

Indole 2-carboxamide derivatives 4 underwent palladium-catalyzed intramolecular cyclization reactions to afford beta-carbolinones or pyrazino[1,2-a]indoles according to different reaction pathways. The complete regioselectivity of the reactions was obtained in different reaction conditions.

Palladium-catalyzed dual C-H or N-H functionalization of unfunctionalized indole derivatives with alkenes and arenes.

Beilstein journal of organic chemistry

Broggini G, Beccalli EM, Fasana A, Gazzola S.
PMID: 23209507
Beilstein J Org Chem. 2012;8:1730-46. doi: 10.3762/bjoc.8.198. Epub 2012 Oct 11.

This review highlights the development of palladium-catalyzed C-H and N-H functionalization reactions involving indole derivatives. These procedures require unactivated starting materials and are respectful of the basic principle of sustainable chemistry tied to atom economy.

First direct measurement of the 17O(p,γ)18F reaction cross section at Gamow energies for classical novae.

Physical review letters

Scott DA, Caciolli A, Di Leva A, Formicola A, Aliotta M, Anders M, Bemmerer D, Broggini C, Campeggio M, Corvisiero P, Elekes Z, Fülöp Z, Gervino G, Guglielmetti A, Gustavino C, Gyürky G, Imbriani G, Junker M, Laubenstein M, Menegazzo R, Marta M, Napolitani E, Prati P, Rigato V, Roca V, Somorjai E, Salvo C, Straniero O, Strieder F, Szücs T, Terrasi F, Trezzi D.
PMID: 23215474
Phys Rev Lett. 2012 Nov 16;109(20):202501. doi: 10.1103/PhysRevLett.109.202501. Epub 2012 Nov 13.

Classical novae are important contributors to the abundances of key isotopes, such as the radioactive (18)F, whose observation by satellite missions could provide constraints on nucleosynthesis models in novae. The (17)O(p,γ)(18)F reaction plays a critical role in the synthesis...

KRas-LCS6 polymorphism does not impact on outcomes in ovarian cancer.

American journal of cancer research

Caiola E, Rulli E, Fruscio R, Buda A, Broggini M, Marabese M.
PMID: 22679560
Am J Cancer Res. 2012;2(3):298-308. Epub 2012 Apr 21.

Epithelial ovarian cancer is a malignancy with high rate of death due to an advanced disease at diagnosis and frequent relapse after chemotherapy. Nowadays, there is a lack of knowledge for clear risk factors and predictive and/or prognostic genetic...

A Systematic Review of NAFLD-Associated Extrahepatic Disorders in Youths.

Journal of clinical medicine

Pacifico L, Perla FM, Roggini M, Andreoli G, D'Avanzo M, Chiesa C.
PMID: 31213030
J Clin Med. 2019 Jun 17;8(6). doi: 10.3390/jcm8060868.

BACKGROUND: There is growing evidence that non-alcoholic fatty liver disease (NAFLD) is a disease affecting not only the liver but also extrahepatic organs.AIM: To investigate whether in youths NAFLD is associated with extrahepatic complications such as subclinical atherosclerosis, cardiac...

Role of mTOR and VEGFR Inhibition in Prevention of Metastatic Tumor Growth in the Spine.

Frontiers in oncology

Kratzsch T, Piffko A, Broggini T, Czabanka M, Vajkoczy P.
PMID: 32140451
Front Oncol. 2020 Feb 19;10:174. doi: 10.3389/fonc.2020.00174. eCollection 2020.

No abstract available.

Inhibition of the Lysophosphatidylinositol Transporter ABCC1 Reduces Prostate Cancer Cell Growth and Sensitizes to Chemotherapy.

Cancers

Emmanouilidi A, Casari I, Gokcen Akkaya B, Maffucci T, Furic L, Guffanti F, Broggini M, Chen X, Maxuitenko YY, Keeton AB, Piazza GA, Linton KJ, Falasca M.
PMID: 32718079
Cancers (Basel). 2020 Jul 23;12(8). doi: 10.3390/cancers12082022.

Expression of ATP-binding cassette (ABC) transporters has long been implicated in cancer chemotherapy resistance. Increased expression of the ABCC subfamily transporters has been reported in prostate cancer, especially in androgen-resistant cases. ABCC transporters are known to efflux drugs but,...

Graves' Disease Induced by Immune Checkpoint Inhibitors: A Case Report and Review of the Literature.

European thyroid journal

Brancatella A, Viola N, Brogioni S, Montanelli L, Sardella C, Vitti P, Marcocci C, Lupi I, Latrofa F.
PMID: 31602361
Eur Thyroid J. 2019 Jul;8(4):192-195. doi: 10.1159/000501824. Epub 2019 Jul 09.

INTRODUCTION: In the last few years, immune checkpoint inhibitors (ICPis) have become a common treatment of cancer. ICPis are associated with peculiar immune side effects, termed immune-related adverse events (irAEs). Thyroid disfunction is a common irAE, but clinical manifestation,...

Replacing Manual Planning of Whole Breast Irradiation With Knowledge-Based Automatic Optimization by Virtual Tangential-Fields Arc Therapy.

Frontiers in oncology

Castriconi R, Esposito PG, Tudda A, Mangili P, Broggi S, Fodor A, Deantoni CL, Longobardi B, Pasetti M, Perna L, Del Vecchio A, Di Muzio NG, Fiorino C.
PMID: 34504790
Front Oncol. 2021 Aug 24;11:712423. doi: 10.3389/fonc.2021.712423. eCollection 2021.

PURPOSE: To implement Knowledge Based (KB) automatic planning for right and left-sided whole breast treatment through a new volumetric technique (ViTAT, Virtual Tangential-fields Arc Therapy) mimicking conventional tangential fields (TF) irradiation.MATERIALS AND METHOD: A total of 193 clinical plans...

Divergent Conversion of 4-Naphthoquinone-substituted 4.

Organic letters

Christodoulou MS, Giofrè S, Beccalli EM, Foschi F, Broggini G.
PMID: 32182085
Org Lett. 2020 Apr 03;22(7):2735-2739. doi: 10.1021/acs.orglett.0c00709. Epub 2020 Mar 17.

4,4-Disubstituted 4

Showing 1 to 12 of 92 entries