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Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase.

ACS medicinal chemistry letters

Tong Y, Torrent M, Florjancic AS, Bromberg KD, Buchanan FG, Ferguson DC, Johnson EF, Lasko LM, Maag D, Merta PJ, Olson AM, Osterling DJ, Soni N, Shoemaker AR, Penning TD.
PMID: 25589931
ACS Med Chem Lett. 2014 Aug 06;6(1):58-62. doi: 10.1021/ml5002745. eCollection 2015 Jan 08.

Aided by molecular modeling, compounds with a pyrimidine-based tricyclic scaffold were designed and confirmed to inhibit Wee1 kinase. Structure-activity studies identified key pharmacophores at the aminoaryl and halo-benzene regions responsible for binding affinity with sub-nM K i values. The...

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Tong Y, Torrent M, Florjancic AS, et al. Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase. ACS Med Chem Lett. 2014;6(1):58-62doi: 10.1021/ml5002745.
Tong, Y., Torrent, M., Florjancic, A. S., Bromberg, K. D., Buchanan, F. G., Ferguson, D. C., Johnson, E. F., Lasko, L. M., Maag, D., Merta, P. J., Olson, A. M., Osterling, D. J., Soni, N., Shoemaker, A. R., & Penning, T. D. (2015). Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase. ACS medicinal chemistry letters, 6(1), 58-62. https://doi.org/10.1021/ml5002745
Tong, Yunsong, et al. "Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase." ACS medicinal chemistry letters vol. 6,1 (2015): 58-62. doi: https://doi.org/10.1021/ml5002745
Tong Y, Torrent M, Florjancic AS, Bromberg KD, Buchanan FG, Ferguson DC, Johnson EF, Lasko LM, Maag D, Merta PJ, Olson AM, Osterling DJ, Soni N, Shoemaker AR, Penning TD. Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase. ACS Med Chem Lett. 2014 Aug 06;6(1):58-62. doi: 10.1021/ml5002745. eCollection 2015 Jan 08. PMID: 25589931; PMCID: PMC4291713.
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Parent and Child Report of Pain and Fatigue in JIA: Does Disagreement between Parent and Child Predict Functional Outcomes?.

Children (Basel, Switzerland)

Gaultney AC, Bromberg MH, Connelly M, Spears T, Schanberg LE.
PMID: 28146097
Children (Basel). 2017 Jan 30;4(2). doi: 10.3390/children4020011.

While previous research in juvenile idiopathic arthritis (JIA) has identified discrepancy between parent and child perception of disease-related symptoms such as pain, the significance and impact of this disagreement has not been characterized. We examined the extent to which...

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Gaultney AC, Bromberg MH, Connelly M, et al. Parent and Child Report of Pain and Fatigue in JIA: Does Disagreement between Parent and Child Predict Functional Outcomes?. Children (Basel). 2017;4(2)doi: 10.3390/children4020011.
Gaultney, A. C., Bromberg, M. H., Connelly, M., Spears, T., & Schanberg, L. E. (2017). Parent and Child Report of Pain and Fatigue in JIA: Does Disagreement between Parent and Child Predict Functional Outcomes?. Children (Basel, Switzerland), 4(2), . https://doi.org/10.3390/children4020011
Gaultney, Amy C, et al. "Parent and Child Report of Pain and Fatigue in JIA: Does Disagreement between Parent and Child Predict Functional Outcomes?." Children (Basel, Switzerland) vol. 4,2 (2017). doi: https://doi.org/10.3390/children4020011
Gaultney AC, Bromberg MH, Connelly M, Spears T, Schanberg LE. Parent and Child Report of Pain and Fatigue in JIA: Does Disagreement between Parent and Child Predict Functional Outcomes?. Children (Basel). 2017 Jan 30;4(2). doi: 10.3390/children4020011. PMID: 28146097; PMCID: PMC5332913.
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Prevalence of atopic dermatitis in infants during the first six months of life: authors' observations.

Postepy dermatologii i alergologii

Kamer B, Pasowska R, Dółka E, Blomberg A, Rotsztejn H.
PMID: 24353486
Postepy Dermatol Alergol. 2013 Oct;30(5):277-81. doi: 10.5114/pdia.2013.38355. Epub 2013 Oct 30.

INTRODUCTION: Atopic dermatitis (AD) is a frequent chronic skin disease in infants. It creates great difficulties, both diagnostic and therapeutic.AIM: To assess the prevalence of atopic dermatitis in infants during the first 6 months of life.MATERIAL AND METHODS: The...

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Kamer B, Pasowska R, Dółka E, et al. Prevalence of atopic dermatitis in infants during the first six months of life: authors' observations. Postepy Dermatol Alergol. 2013;30(5):277-81doi: 10.5114/pdia.2013.38355.
Kamer, B., Pasowska, R., Dółka, E., Blomberg, A., & Rotsztejn, H. (2013). Prevalence of atopic dermatitis in infants during the first six months of life: authors' observations. Postepy dermatologii i alergologii, 30(5), 277-81. https://doi.org/10.5114/pdia.2013.38355
Kamer, Barbara, et al. "Prevalence of atopic dermatitis in infants during the first six months of life: authors' observations." Postepy dermatologii i alergologii vol. 30,5 (2013): 277-81. doi: https://doi.org/10.5114/pdia.2013.38355
Kamer B, Pasowska R, Dółka E, Blomberg A, Rotsztejn H. Prevalence of atopic dermatitis in infants during the first six months of life: authors' observations. Postepy Dermatol Alergol. 2013 Oct;30(5):277-81. doi: 10.5114/pdia.2013.38355. Epub 2013 Oct 30. PMID: 24353486; PMCID: PMC3858654.
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Idiopathic Esophageal Ulcers in AIDS Completely Healed With Highly Active Anti-Retroviral Therapy.

ACG case reports journal

Bromberg DJ, Gill JA.
PMID: 26157937
ACG Case Rep J. 2015 Apr 10;2(3):127-8. doi: 10.14309/crj.2015.28. eCollection 2015 Apr.

No abstract available.

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Bromberg DJ, Gill JA. Idiopathic Esophageal Ulcers in AIDS Completely Healed With Highly Active Anti-Retroviral Therapy. ACG Case Rep J. 2015;2(3):127-8doi: 10.14309/crj.2015.28.
Bromberg, D. J., & Gill, J. A. (2015). Idiopathic Esophageal Ulcers in AIDS Completely Healed With Highly Active Anti-Retroviral Therapy. ACG case reports journal, 2(3), 127-8. https://doi.org/10.14309/crj.2015.28
Bromberg, David J, and Gill, Jeffrey A. "Idiopathic Esophageal Ulcers in AIDS Completely Healed With Highly Active Anti-Retroviral Therapy." ACG case reports journal vol. 2,3 (2015): 127-8. doi: https://doi.org/10.14309/crj.2015.28
Bromberg DJ, Gill JA. Idiopathic Esophageal Ulcers in AIDS Completely Healed With Highly Active Anti-Retroviral Therapy. ACG Case Rep J. 2015 Apr 10;2(3):127-8. doi: 10.14309/crj.2015.28. eCollection 2015 Apr. PMID: 26157937; PMCID: PMC4435398.
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EPA's monitoring program at Love Canal 1980.

Environmental monitoring and assessment

Hauser TR, Bromberg SM.
PMID: 24264296
Environ Monit Assess. 1982 Sep;2(3):249-71. doi: 10.1007/BF00394456.

As stated at the beginning of this paper conclusions reached thus far cannot be discussed in this paper. However, a great deal of information is available for examination.EPA displayed its ability to coordinate widely separated laboratories, both Federal and...

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Hauser TR, Bromberg SM. EPA's monitoring program at Love Canal 1980. Environ Monit Assess. 1982;2(3):249-71doi: 10.1007/BF00394456.
Hauser, T. R., & Bromberg, S. M. (1982). EPA's monitoring program at Love Canal 1980. Environmental monitoring and assessment, 2(3), 249-71. https://doi.org/10.1007/BF00394456
Hauser, T R, and Bromberg, S M. "EPA's monitoring program at Love Canal 1980." Environmental monitoring and assessment vol. 2,3 (1982): 249-71. doi: https://doi.org/10.1007/BF00394456
Hauser TR, Bromberg SM. EPA's monitoring program at Love Canal 1980. Environ Monit Assess. 1982 Sep;2(3):249-71. doi: 10.1007/BF00394456. PMID: 24264296.
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Drug-induced myopathies.

Journal of clinical neuromuscular disease

Bromberg MB.
PMID: 19078789
J Clin Neuromuscul Dis. 2005 Dec;7(2):79-87. doi: 10.1097/01.cnd.0000194632.54771.cf.

The incidence of drug-induced myopathic disorders is unknown. Estimates depend in part on definitions used. Cholesterol-lowering agents have been singled out as common offenders. However, the large number of available drugs, polypharmacy especially among the elderly, and known risk...

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Bromberg MB. Drug-induced myopathies. J Clin Neuromuscul Dis. 2005;7(2):79-87doi: 10.1097/01.cnd.0000194632.54771.cf.
Bromberg, M. B. (2005). Drug-induced myopathies. Journal of clinical neuromuscular disease, 7(2), 79-87. https://doi.org/10.1097/01.cnd.0000194632.54771.cf
Bromberg, Mark B. "Drug-induced myopathies." Journal of clinical neuromuscular disease vol. 7,2 (2005): 79-87. doi: https://doi.org/10.1097/01.cnd.0000194632.54771.cf
Bromberg MB. Drug-induced myopathies. J Clin Neuromuscul Dis. 2005 Dec;7(2):79-87. doi: 10.1097/01.cnd.0000194632.54771.cf. PMID: 19078789.
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(45)Ca efflux and agonist induced changes in force in a model of thrombin activated platelets.

Platelets

Bromberg ME, Sevy RW, Salganicoff L.
PMID: 21043906
Platelets. 1992;3(3):137-44. doi: 10.3109/09537109209013174.

(45)Ca(2+) and (3)H sorbitol were loaded by incubation into a model of thrombin activated, irreversibly aggregated platelets. Total Ca, measured by atomic absorption, was approximately 4.0 nmoles/mg wet weight. 55% of the total Ca(2+) was exchangeable with (45)Ca(2+), 14%...

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Bromberg ME, Sevy RW, Salganicoff L. (45)Ca efflux and agonist induced changes in force in a model of thrombin activated platelets. Platelets. 1992;3(3):137-44doi: 10.3109/09537109209013174.
Bromberg, M. E., Sevy, R. W., & Salganicoff, L. (1992). (45)Ca efflux and agonist induced changes in force in a model of thrombin activated platelets. Platelets, 3(3), 137-44. https://doi.org/10.3109/09537109209013174
Bromberg, M E, et al. "(45)Ca efflux and agonist induced changes in force in a model of thrombin activated platelets." Platelets vol. 3,3 (1992): 137-44. doi: https://doi.org/10.3109/09537109209013174
Bromberg ME, Sevy RW, Salganicoff L. (45)Ca efflux and agonist induced changes in force in a model of thrombin activated platelets. Platelets. 1992;3(3):137-44. doi: 10.3109/09537109209013174. PMID: 21043906.
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Leukocyte: tempus fugit vel carpe diem.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Maltzman JS, Bromberg JS.
PMID: 22741751
Am J Transplant. 2012 Jul;12(7):1665. doi: 10.1111/j.1600-6143.2012.04187.x.

No abstract available.

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Maltzman JS, Bromberg JS. Leukocyte: tempus fugit vel carpe diem. Am J Transplant. 2012;12(7):1665doi: 10.1111/j.1600-6143.2012.04187.x.
Maltzman, J. S., & Bromberg, J. S. (2012). Leukocyte: tempus fugit vel carpe diem. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 12(7), 1665. https://doi.org/10.1111/j.1600-6143.2012.04187.x
Maltzman, Jonathan S, and Bromberg, Jonathan S. "Leukocyte: tempus fugit vel carpe diem." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons vol. 12,7 (2012): 1665. doi: https://doi.org/10.1111/j.1600-6143.2012.04187.x
Maltzman JS, Bromberg JS. Leukocyte: tempus fugit vel carpe diem. Am J Transplant. 2012 Jul;12(7):1665. doi: 10.1111/j.1600-6143.2012.04187.x. PMID: 22741751.
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Evolutionary loss of 8-oxo-G repair components among eukaryotes.

Genome integrity

Jansson K, Blomberg A, Sunnerhagen P, Alm Rosenblad M.
PMID: 20809962
Genome Integr. 2010 Sep 01;1(1):12. doi: 10.1186/2041-9414-1-12.

BACKGROUND: We have examined the phylogenetic pattern among eukaryotes of homologues of the E. coli 7,8-dihydro-8-oxoguanine (8-oxo-G) repair enzymes MutY, MutM, and MutT.RESULTS: These DNA repair enzymes are present in all large phylogenetic groups, with MutM homologues being the...

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Jansson K, Blomberg A, Sunnerhagen P, et al. Evolutionary loss of 8-oxo-G repair components among eukaryotes. Genome Integr. 2010;1(1):12doi: 10.1186/2041-9414-1-12.
Jansson, K., Blomberg, A., Sunnerhagen, P., & Alm Rosenblad, M. (2010). Evolutionary loss of 8-oxo-G repair components among eukaryotes. Genome integrity, 1(1), 12. https://doi.org/10.1186/2041-9414-1-12
Jansson, Kristina, et al. "Evolutionary loss of 8-oxo-G repair components among eukaryotes." Genome integrity vol. 1,1 (2010): 12. doi: https://doi.org/10.1186/2041-9414-1-12
Jansson K, Blomberg A, Sunnerhagen P, Alm Rosenblad M. Evolutionary loss of 8-oxo-G repair components among eukaryotes. Genome Integr. 2010 Sep 01;1(1):12. doi: 10.1186/2041-9414-1-12. PMID: 20809962; PMCID: PMC2941479.
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Literature Watch: implications for transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Turnquist HR, Bromberg JS, Bromberg JS.
PMID: 23009135
Am J Transplant. 2012 Oct;12(10):2567. doi: 10.1111/j.1600-6143.2012.04297.x.

No abstract available.

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Turnquist HR, Bromberg JS, Bromberg JS. Literature Watch: implications for transplantation. Am J Transplant. 2012;12(10):2567doi: 10.1111/j.1600-6143.2012.04297.x.
Turnquist, H. R., Bromberg, J. S., & Bromberg, J. S. (2012). Literature Watch: implications for transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 12(10), 2567. https://doi.org/10.1111/j.1600-6143.2012.04297.x
Turnquist, Heth R, et al. "Literature Watch: implications for transplantation." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons vol. 12,10 (2012): 2567. doi: https://doi.org/10.1111/j.1600-6143.2012.04297.x
Turnquist HR, Bromberg JS, Bromberg JS. Literature Watch: implications for transplantation. Am J Transplant. 2012 Oct;12(10):2567. doi: 10.1111/j.1600-6143.2012.04297.x. PMID: 23009135.
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The I-J subregion and surveillance.

Immunology today

Greene MI, Perry LL, Sy MS, Bromberg JS.
PMID: 25290860
Immunol Today. 1981 Feb;2(2):23-5. doi: 10.1016/0167-5699(81)90030-X.

A discussion of the control exerted by the I-J subregion of the H-2 complex over suppression, tolerance and self/non-self discrimination, and its implications in the study of tumour immunity and autoimmunity.

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Greene MI, Perry LL, Sy MS, et al. The I-J subregion and surveillance. Immunol Today. 1981;2(2):23-5doi: 10.1016/0167-5699(81)90030-X.
Greene, M. I., Perry, L. L., Sy, M. S., & Bromberg, J. S. (1981). The I-J subregion and surveillance. Immunology today, 2(2), 23-5. https://doi.org/10.1016/0167-5699(81)90030-X
Greene, M I, et al. "The I-J subregion and surveillance." Immunology today vol. 2,2 (1981): 23-5. doi: https://doi.org/10.1016/0167-5699(81)90030-X
Greene MI, Perry LL, Sy MS, Bromberg JS. The I-J subregion and surveillance. Immunol Today. 1981 Feb;2(2):23-5. doi: 10.1016/0167-5699(81)90030-X. PMID: 25290860.
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Sullivan's role in health policy reform.

Review (Federation of American Health Systems)

Bromberg MD.
PMID: 10106269
Rev Fed Am Health Syst. 1990 Sep-Oct;23(5):5.

No abstract available.

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Bromberg MD. Sullivan's role in health policy reform. Rev Fed Am Health Syst. 1990;23(5):5
Bromberg, M. D. (1990). Sullivan's role in health policy reform. Review (Federation of American Health Systems), 23(5), 5.
Bromberg, M D. "Sullivan's role in health policy reform." Review (Federation of American Health Systems) vol. 23,5 (1990): 5.
Bromberg MD. Sullivan's role in health policy reform. Rev Fed Am Health Syst. 1990 Sep-Oct;23(5):5. PMID: 10106269.
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Showing 1 to 12 of 176 entries