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Showing 1 to 12 of 145 entries
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Nitroalkenes confer acute cardioprotection via adenine nucleotide translocase 1.

The Journal of biological chemistry

Nadtochiy SM, Zhu QM, Urciuoli W, Rafikov R, Black SM, Brookes PS.
PMID: 26684340
J Biol Chem. 2015 Dec 18;290(51):30267. doi: 10.1074/jbc.A111.298406.

No abstract available.

Imaging Water Dissociation on TiO(2)(110).

Physical review letters

Brookes IM, Muryn CA, Thornton G.
PMID: 11800844
Phys Rev Lett. 2001 Dec 24;87(26):266103. doi: 10.1103/PhysRevLett.87.266103. Epub 2001 Dec 06.

Scanning tunneling microscopy has been used to identify the adsorption site of H(2)O on TiO(2)(110)-(1 x 1) at 150 K, and to monitor the site of the dissociation products at 290 K. Water adsorbs onto the rows of fivefold...

Mitochondrial nitric oxide synthase.

Mitochondrion

Brookes PS.
PMID: 16120354
Mitochondrion. 2004 Mar;3(4):187-204. doi: 10.1016/j.mito.2003.10.001.

Nitric oxide (NO*) can bind to and inhibit the terminal enzyme of the mitochondrial respiratory chain, cytochrome c oxidase (complex IV). In vivo, NO* is made by the NO* synthase (NOS) family of enzymes, and considerable debate has recently...

The reaction of mustard gas with nucleic acids in vitro and in vivo.

The Biochemical journal

Brookes P, Lawley PD.
PMID: 16748853
Biochem J. 1960 Dec;77(3):478-84. doi: 10.1042/bj0770478.

No abstract available.

Semantically enabling a genome-wide association study database.

Journal of biomedical semantics

Beck T, Free RC, Thorisson GA, Brookes AJ.
PMID: 23244533
J Biomed Semantics. 2012 Dec 17;3(1):9. doi: 10.1186/2041-1480-3-9.

BACKGROUND: The amount of data generated from genome-wide association studies (GWAS) has grown rapidly, but considerations for GWAS phenotype data reuse and interchange have not kept pace. This impacts on the work of GWAS Central - a free and...

Accuracy of the lattice Boltzmann method for low-speed noncontinuum flows.

Physical review. E, Statistical, nonlinear, and soft matter physics

Shi Y, Brookes PL, Yap YW, Sader JE.
PMID: 21599233
Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Apr;83(4):045701. doi: 10.1103/PhysRevE.83.045701. Epub 2011 Apr 22.

Simulation of noncontinuum gas flows presents tremendous challenges, especially for nanoscale devices that usually exhibit low speeds and isothermal conditions. Such simulations are often achieved through use of the Boltzmann Bhatnagar-Gross-Krook equation, which forms the foundation for the lattice...

Effect of solvent polarity on the vibrational dephasing dynamics of the nitrosyl stretch in an Fe(II) complex revealed by 2D IR spectroscopy.

The journal of physical chemistry. A

Brookes JF, Slenkamp KM, Lynch MS, Khalil M.
PMID: 23480848
J Phys Chem A. 2013 Jul 25;117(29):6234-43. doi: 10.1021/jp4005345. Epub 2013 Mar 25.

The vibrational dephasing dynamics of the nitrosyl stretching vibration (ν(NO)) in sodium nitroprusside (SNP, Na2[Fe(CN)5NO]·2H2O) are investigated using two-dimensional infrared (2D IR) spectroscopy. The ν(NO) in SNP acts as a model system for the nitrosyl ligand found in metalloproteins...

Cardiac metabolic effects of K.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Smith CO, Wang YT, Nadtochiy SM, Miller JH, Jonas EA, Dirksen RT, Nehrke K, Brookes PS.
PMID: 29863912
FASEB J. 2018 Jun 04;fj201800139R. doi: 10.1096/fj.201800139R. Epub 2018 Jun 04.

Controversy surrounds the molecular identity of mitochondrial K

Axial stereocontrol in tropos dibenz[c,e]azepines: the individual and cooperative effects of alkyl substituents.

Organic & biomolecular chemistry

Balgobin SMC, Brookes DJ, Jiang J, Pritchard RG, Wallace TW.
PMID: 29177299
Org Biomol Chem. 2017 Dec 13;15(48):10184-10199. doi: 10.1039/c7ob02385e.

6,7-Dihydro-5H-dibenz[c,e]azepines, a class of secondary amine incorporating a centre-axis chirality relay, can be prepared from N-(2-bromobenzyl)-N-(1-arylalkyl)methanesulfonamides via Pd-catalysed intramolecular direct arylation, and methylated at C(7) via the 5,7-trans diastereoselective addition of methylmagnesium bromide to the derived N-benzylazepinium tetraphenylborate. Using...

Memory-Assisted Exciton Diffusion in the Chlorosome Light-Harvesting Antenna of Green Sulfur Bacteria.

The journal of physical chemistry letters

Fujita T, Brookes JC, Saikin SK, Aspuru-Guzik A.
PMID: 26292114
J Phys Chem Lett. 2012 Sep 06;3(17):2357-61. doi: 10.1021/jz3008326. Epub 2012 Aug 13.

Chlorosomes are likely the largest and most efficient natural light-harvesting photosynthetic antenna systems. They are composed of large numbers of bacteriochlorophylls organized into supramolecular aggregates. We explore the microscopic origin of the fast excitation energy transfer in the chlorosome...

Response of dissolved organic matter optical properties to net inflow runoff in a large fluvial plain lake and the connecting channels.

The Science of the total environment

Zhou Y, Yao X, Zhang Y, Zhang Y, Shi K, Tang X, Qin B, Podgorski DC, Brookes JD, Jeppesen E.
PMID: 29929326
Sci Total Environ. 2018 Oct 15;639:876-887. doi: 10.1016/j.scitotenv.2018.05.180. Epub 2018 May 26.

Fluvial plain lake watersheds are usually highly urbanized and have high concentrations of chromophoric dissolved organic matter (CDOM). CDOM derived from the connecting urban channels usually share strong terrestrial and anthropogenic signals and net inflow runoff (Q

Relating Urban Biodiversity to Human Health With the 'Holobiont' Concept.

Frontiers in microbiology

Mills JG, Brookes JD, Gellie NJC, Liddicoat C, Lowe AJ, Sydnor HR, Thomas T, Weinstein P, Weyrich LS, Breed MF.
PMID: 30972043
Front Microbiol. 2019 Mar 26;10:550. doi: 10.3389/fmicb.2019.00550. eCollection 2019.

A relatively unaccounted ecosystem service from biodiversity is the benefit to human health via symbiotic microbiota from our environment. This benefit occurs because humans evolved alongside microbes and have been constantly exposed to diverse microbiota. Plants and animals, including...

Showing 1 to 12 of 145 entries