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Showing 1 to 12 of 155 entries
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FDA Facilitated Regulatory Pathways: Visualizing Their Characteristics, Development, and Authorization Timelines.

Frontiers in pharmacology

Liberti L, Bujar M, Breckenridge A, Hoekman J, McAuslane N, Stolk P, Leufkens H.
PMID: 28420989
Front Pharmacol. 2017 Apr 03;8:161. doi: 10.3389/fphar.2017.00161. eCollection 2017.

The US Food and Drug Administration (FDA) has four facilitated regulatory pathways (FRPs): Fast Track (FT), Breakthrough Therapy (BTD), Priority Review (PR), and Accelerated Approval (AA). Only PR specifies an expedited review timeline (6 months). We sought to determine...

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Liberti L, Bujar M, Breckenridge A, et al. FDA Facilitated Regulatory Pathways: Visualizing Their Characteristics, Development, and Authorization Timelines. Front Pharmacol. 2017;8:161doi: 10.3389/fphar.2017.00161.
Liberti, L., Bujar, M., Breckenridge, A., Hoekman, J., McAuslane, N., Stolk, P., & Leufkens, H. (2017). FDA Facilitated Regulatory Pathways: Visualizing Their Characteristics, Development, and Authorization Timelines. Frontiers in pharmacology, 8161. https://doi.org/10.3389/fphar.2017.00161
Liberti, Lawrence, et al. "FDA Facilitated Regulatory Pathways: Visualizing Their Characteristics, Development, and Authorization Timelines." Frontiers in pharmacology vol. 8 (2017): 161. doi: https://doi.org/10.3389/fphar.2017.00161
Liberti L, Bujar M, Breckenridge A, Hoekman J, McAuslane N, Stolk P, Leufkens H. FDA Facilitated Regulatory Pathways: Visualizing Their Characteristics, Development, and Authorization Timelines. Front Pharmacol. 2017 Apr 03;8:161. doi: 10.3389/fphar.2017.00161. eCollection 2017. PMID: 28420989; PMCID: PMC5376616.
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2-bromo-5-hydroxybenzaldehyde.

Acta crystallographica. Section C, Crystal structure communications

Beja AM, Paixao JA, Silva MR, da Veiga LA, Gonsalves AM, Serra AC.
PMID: 10777949
Acta Crystallogr C. 2000 Mar;56:354-5. doi: 10.1107/s0108270199015267.

No abstract available.

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Beja AM, Paixao JA, Silva MR, et al. 2-bromo-5-hydroxybenzaldehyde. Acta Crystallogr C. 2000;56:354-5doi: 10.1107/s0108270199015267.
Beja, A. M., Paixao, J. A., Silva, M. R., da Veiga LA, Gonsalves, A. M., & Serra, A. C. (2000). 2-bromo-5-hydroxybenzaldehyde. Acta crystallographica. Section C, Crystal structure communications, 56354-5. https://doi.org/10.1107/s0108270199015267
Beja, et al. "2-bromo-5-hydroxybenzaldehyde." Acta crystallographica. Section C, Crystal structure communications vol. 56 (2000): 354-5. doi: https://doi.org/10.1107/s0108270199015267
Beja AM, Paixao JA, Silva MR, da Veiga LA, Gonsalves AM, Serra AC. 2-bromo-5-hydroxybenzaldehyde. Acta Crystallogr C. 2000 Mar;56:354-5. doi: 10.1107/s0108270199015267. PMID: 10777949.
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An X-ray diffraction and MAS NMR study of the thermal expansion properties of calcined siliceous ferrierite.

Journal of the American Chemical Society

Bull I, Lightfoot P, Villaescusa LA, Bull LM, Gover RK, Evans JS, Morris RE.
PMID: 12670258
J Am Chem Soc. 2003 Apr 09;125(14):4342-9. doi: 10.1021/ja0292400.

Powder and single-crystal X-ray diffraction, combined with MAS NMR measurements, has been used to study the thermal expansion of siliceous zeolite ferrierite as it approaches a second-order displacive phase transition from a low-symmetry (Pnnm) to a high-symmetry (Immm) structure....

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Bull I, Lightfoot P, Villaescusa LA, et al. An X-ray diffraction and MAS NMR study of the thermal expansion properties of calcined siliceous ferrierite. J Am Chem Soc. 2003;125(14):4342-9doi: 10.1021/ja0292400.
Bull, I., Lightfoot, P., Villaescusa, L. A., Bull, L. M., Gover, R. K., Evans, J. S., & Morris, R. E. (2003). An X-ray diffraction and MAS NMR study of the thermal expansion properties of calcined siliceous ferrierite. Journal of the American Chemical Society, 125(14), 4342-9. https://doi.org/10.1021/ja0292400
Bull, Ivor, et al. "An X-ray diffraction and MAS NMR study of the thermal expansion properties of calcined siliceous ferrierite." Journal of the American Chemical Society vol. 125,14 (2003): 4342-9. doi: https://doi.org/10.1021/ja0292400
Bull I, Lightfoot P, Villaescusa LA, Bull LM, Gover RK, Evans JS, Morris RE. An X-ray diffraction and MAS NMR study of the thermal expansion properties of calcined siliceous ferrierite. J Am Chem Soc. 2003 Apr 09;125(14):4342-9. doi: 10.1021/ja0292400. PMID: 12670258.
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Very short F-H...F hydrogen bond in L-argininium fluoride hydrogen fluoride.

Acta crystallographica. Section C, Crystal structure communications

Silva MR, Paixao JA, Beja AM, da Veiga LA.
PMID: 10710688
Acta Crystallogr C. 2000 Jan;56:104-6. doi: 10.1107/s0108270199011981.

No abstract available.

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Silva MR, Paixao JA, Beja AM, et al. Very short F-H...F hydrogen bond in L-argininium fluoride hydrogen fluoride. Acta Crystallogr C. 2000;56:104-6doi: 10.1107/s0108270199011981.
Silva, M. R., Paixao, J. A., Beja, A. M., & da Veiga LA. (2000). Very short F-H...F hydrogen bond in L-argininium fluoride hydrogen fluoride. Acta crystallographica. Section C, Crystal structure communications, 56104-6. https://doi.org/10.1107/s0108270199011981
Silva, et al. "Very short F-H...F hydrogen bond in L-argininium fluoride hydrogen fluoride." Acta crystallographica. Section C, Crystal structure communications vol. 56 (2000): 104-6. doi: https://doi.org/10.1107/s0108270199011981
Silva MR, Paixao JA, Beja AM, da Veiga LA. Very short F-H...F hydrogen bond in L-argininium fluoride hydrogen fluoride. Acta Crystallogr C. 2000 Jan;56:104-6. doi: 10.1107/s0108270199011981. PMID: 10710688.
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Reactivity of 2-halo-2H-azirines. 1. Reactions with nucleophiles.

The Journal of organic chemistry

Pinho e Melo TM, Lopes CS, Gonsalves AM, Beja AM, Paixão JA, Silva MR, da Veiga LA.
PMID: 11777440
J Org Chem. 2002 Jan 11;67(1):66-71. doi: 10.1021/jo010504v.

Nucleophilic substitution reactions of 2-halo-2H-azirines 1a, 1b, 1d, and 1e with potassium phthalimide and aniline allowed the preparation of new substituted 2H-azirines 2-5. The reactions of 2-bromo-2H-azirine 1a with methylamine led to the synthesis of alpha-diimines 7 and 8....

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Pinho e Melo TM, Lopes CS, Gonsalves AM, et al. Reactivity of 2-halo-2H-azirines. 1. Reactions with nucleophiles. J Org Chem. 2002;67(1):66-71doi: 10.1021/jo010504v.
Pinho e Melo, T. M., Lopes, C. S., Gonsalves, A. M., Beja, A. M., Paixão, J. A., Silva, M. R., & da Veiga, L. A. (2002). Reactivity of 2-halo-2H-azirines. 1. Reactions with nucleophiles. The Journal of organic chemistry, 67(1), 66-71. https://doi.org/10.1021/jo010504v
Pinho e Melo, Teresa M V D, et al. "Reactivity of 2-halo-2H-azirines. 1. Reactions with nucleophiles." The Journal of organic chemistry vol. 67,1 (2002): 66-71. doi: https://doi.org/10.1021/jo010504v
Pinho e Melo TM, Lopes CS, Gonsalves AM, Beja AM, Paixão JA, Silva MR, da Veiga LA. Reactivity of 2-halo-2H-azirines. 1. Reactions with nucleophiles. J Org Chem. 2002 Jan 11;67(1):66-71. doi: 10.1021/jo010504v. PMID: 11777440.
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Effect of a simple versus a complex matrix on the polarity of cardiomyocytes in culture.

Journal of burns and wounds

Davis RA, van Winkle WB, Buja LM, Poindexter BJ, Bick RJ.
PMID: 16921416
J Burns Wounds. 2006 Mar 30;5:e3.

OBJECTIVE: The objective of this study was to observe the effects of cell culture on cellular polarity in cardiomyocytes as influenced by cytoskeletal proteins.METHODS: Cardiomyocytes from adult and neonatal rats were isolated and grown on 2 different extracellular matrices--laminin...

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Davis RA, van Winkle WB, Buja LM, et al. Effect of a simple versus a complex matrix on the polarity of cardiomyocytes in culture. J Burns Wounds. 2006;5:e3
Davis, R. A., van Winkle, W. B., Buja, L. M., Poindexter, B. J., & Bick, R. J. (2006). Effect of a simple versus a complex matrix on the polarity of cardiomyocytes in culture. Journal of burns and wounds, 5e3.
Davis, Rachel A, et al. "Effect of a simple versus a complex matrix on the polarity of cardiomyocytes in culture." Journal of burns and wounds vol. 5 (2006): e3.
Davis RA, van Winkle WB, Buja LM, Poindexter BJ, Bick RJ. Effect of a simple versus a complex matrix on the polarity of cardiomyocytes in culture. J Burns Wounds. 2006 Mar 30;5:e3. PMID: 16921416; PMCID: PMC1687145.
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Nuclear localization of HBD-1 in human keratinocytes.

Journal of burns and wounds

Bick RJ, Poindexter BJ, Buja LM, Lawyer CH, Milner SM, Bhat S.
PMID: 18091980
J Burns Wounds. 2007 Aug 24;7:e3.

OBJECTIVE: Human defensins and cathelicidins are a family of cationic antimicrobial peptides (AMPs), which play multiple roles in both innate and adaptive immune systems. They have direct antimicrobial activity against several microorganisms including burn pathogens. The majority of components...

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Bick RJ, Poindexter BJ, Buja LM, et al. Nuclear localization of HBD-1 in human keratinocytes. J Burns Wounds. 2007;7:e3
Bick, R. J., Poindexter, B. J., Buja, L. M., Lawyer, C. H., Milner, S. M., & Bhat, S. (2007). Nuclear localization of HBD-1 in human keratinocytes. Journal of burns and wounds, 7e3.
Bick, Roger J, et al. "Nuclear localization of HBD-1 in human keratinocytes." Journal of burns and wounds vol. 7 (2007): e3.
Bick RJ, Poindexter BJ, Buja LM, Lawyer CH, Milner SM, Bhat S. Nuclear localization of HBD-1 in human keratinocytes. J Burns Wounds. 2007 Aug 24;7:e3. PMID: 18091980; PMCID: PMC2064969.
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Depressive symptoms in patients with type 2 diabetes mellitus: do stress and coping matter?.

Stress and health : journal of the International Society for the Investigation of Stress

Shah BM, Gupchup GV, Borrego ME, Raisch DW, Knapp KK.
PMID: 22282035
Stress Health. 2012 Apr;28(2):111-22. doi: 10.1002/smi.1410. Epub 2011 Jun 16.

This article examines the relationship among diabetes-related stress, appraisal, coping and depressive symptoms in patients with type 2 diabetes mellitus (T2DM) using the transactional model of stress and coping (TMSC) as the theoretical framework. In this cross-sectional study, a...

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Shah BM, Gupchup GV, Borrego ME, et al. Depressive symptoms in patients with type 2 diabetes mellitus: do stress and coping matter?. Stress Health. 2011;28(2):111-22doi: 10.1002/smi.1410.
Shah, B. M., Gupchup, G. V., Borrego, M. E., Raisch, D. W., & Knapp, K. K. (2012). Depressive symptoms in patients with type 2 diabetes mellitus: do stress and coping matter?. Stress and health : journal of the International Society for the Investigation of Stress, 28(2), 111-22. https://doi.org/10.1002/smi.1410
Shah, Bijal M, et al. "Depressive symptoms in patients with type 2 diabetes mellitus: do stress and coping matter?." Stress and health : journal of the International Society for the Investigation of Stress vol. 28,2 (2012): 111-22. doi: https://doi.org/10.1002/smi.1410
Shah BM, Gupchup GV, Borrego ME, Raisch DW, Knapp KK. Depressive symptoms in patients with type 2 diabetes mellitus: do stress and coping matter?. Stress Health. 2012 Apr;28(2):111-22. doi: 10.1002/smi.1410. Epub 2011 Jun 16. PMID: 22282035.
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Cerebrovascular disorders: role of aging.

Journal of aging research

Popa-Wagner A, Buga AM, Turner RC, Rosen CL, Toescu E.
PMID: 22523684
J Aging Res. 2012;2012:128146. doi: 10.1155/2012/128146. Epub 2012 Mar 19.

No abstract available.

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Popa-Wagner A, Buga AM, Turner RC, et al. Cerebrovascular disorders: role of aging. J Aging Res. 2012;2012:128146doi: 10.1155/2012/128146.
Popa-Wagner, A., Buga, A. M., Turner, R. C., Rosen, C. L., & Toescu, E. (2012). Cerebrovascular disorders: role of aging. Journal of aging research, 2012128146. https://doi.org/10.1155/2012/128146
Popa-Wagner, Aurel, et al. "Cerebrovascular disorders: role of aging." Journal of aging research vol. 2012 (2012): 128146. doi: https://doi.org/10.1155/2012/128146
Popa-Wagner A, Buga AM, Turner RC, Rosen CL, Toescu E. Cerebrovascular disorders: role of aging. J Aging Res. 2012;2012:128146. doi: 10.1155/2012/128146. Epub 2012 Mar 19. PMID: 22523684; PMCID: PMC3317098.
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The benefit of the European User Community from transnational access to national radiation facilities.

Journal of synchrotron radiation

Barrier E, Braz Fernandes FM, Bujan M, Feiters MC, Froideval A, Ghijsen J, Hase T, Hough MA, Jergel M, Jimenez I, Kajander T, Kikas A, Kokkinidis M, Kover L, Larsen HB, Lawson DM, Lawniczak-Jablonska K, Mariani C, Mikulik P, Monnier J, Morera S, McGuinness C, Müller-Buschbaum P, Meedom Nielson M, Pietsch U, Tromp M, Simon M, Stangl J, Zanotti G.
PMID: 24763656
J Synchrotron Radiat. 2014 May;21:638-9. doi: 10.1107/S1600577514007619. Epub 2014 Apr 24.

Transnational access (TNA) to national radiation sources is presently provided via programmes of the European Commission by BIOSTRUCT-X and CALIPSO with a major benefit for scientists from European countries. Entirely based on scientific merit, TNA allows all European scientists...

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Barrier E, Braz Fernandes FM, Bujan M, et al. The benefit of the European User Community from transnational access to national radiation facilities. J Synchrotron Radiat. 2014;21:638-9doi: 10.1107/S1600577514007619.
Barrier, E., Braz Fernandes, F. M., Bujan, M., Feiters, M. C., Froideval, A., Ghijsen, J., Hase, T., Hough, M. A., Jergel, M., Jimenez, I., Kajander, T., Kikas, A., Kokkinidis, M., Kover, L., Larsen, H. B., Lawson, D. M., Lawniczak-Jablonska, K., Mariani, C., Mikulik, P., Monnier, J., Morera, S., McGuinness, C., Müller-Buschbaum, P., Meedom Nielson, M., Pietsch, U., Tromp, M., Simon, M., Stangl, J., & Zanotti, G. (2014). The benefit of the European User Community from transnational access to national radiation facilities. Journal of synchrotron radiation, 21638-9. https://doi.org/10.1107/S1600577514007619
Barrier, Elise, et al. "The benefit of the European User Community from transnational access to national radiation facilities." Journal of synchrotron radiation vol. 21 (2014): 638-9. doi: https://doi.org/10.1107/S1600577514007619
Barrier E, Braz Fernandes FM, Bujan M, Feiters MC, Froideval A, Ghijsen J, Hase T, Hough MA, Jergel M, Jimenez I, Kajander T, Kikas A, Kokkinidis M, Kover L, Larsen HB, Lawson DM, Lawniczak-Jablonska K, Mariani C, Mikulik P, Monnier J, Morera S, McGuinness C, Müller-Buschbaum P, Meedom Nielson M, Pietsch U, Tromp M, Simon M, Stangl J, Zanotti G. The benefit of the European User Community from transnational access to national radiation facilities. J Synchrotron Radiat. 2014 May;21:638-9. doi: 10.1107/S1600577514007619. Epub 2014 Apr 24. PMID: 24763656.
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The Importance of the Autopsy in Medicine: Perspectives of Pathology Colleagues.

Academic pathology

Buja LM, Barth RF, Krueger GR, Brodsky SV, Hunter RL.
PMID: 30886893
Acad Pathol. 2019 Mar 10;6:2374289519834041. doi: 10.1177/2374289519834041. eCollection 2019.

This article presents a perspective on the importance of the autopsy in medical practice and science based on experiences of the authors as physician-scientists involved in autopsy practice. Our perspectives are presented on the seminal contributions of the autopsy...

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Buja LM, Barth RF, Krueger GR, et al. The Importance of the Autopsy in Medicine: Perspectives of Pathology Colleagues. Acad Pathol. 2019;6:2374289519834041doi: 10.1177/2374289519834041.
Buja, L. M., Barth, R. F., Krueger, G. R., Brodsky, S. V., & Hunter, R. L. (2019). The Importance of the Autopsy in Medicine: Perspectives of Pathology Colleagues. Academic pathology, 62374289519834041. https://doi.org/10.1177/2374289519834041
Buja, Louis Maximilian, et al. "The Importance of the Autopsy in Medicine: Perspectives of Pathology Colleagues." Academic pathology vol. 6 (2019): 2374289519834041. doi: https://doi.org/10.1177/2374289519834041
Buja LM, Barth RF, Krueger GR, Brodsky SV, Hunter RL. The Importance of the Autopsy in Medicine: Perspectives of Pathology Colleagues. Acad Pathol. 2019 Mar 10;6:2374289519834041. doi: 10.1177/2374289519834041. eCollection 2019. PMID: 30886893; PMCID: PMC6410379.
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"I'm Stuck": Women's Navigations of Social Networks and Prescription Drug Misuse in Central Appalachia.

North American dialogue : newsletter of the Society for the Anthropology of North America

Buer LM, Leukefeld CG, Havens JR.
PMID: 28736509
North Am Dialogue. 2016;19(2):70-84. doi: 10.1111/nad.12044. Epub 2016 Oct 28.

This study utilizes anthropological analyses of kinship, care, gendered inequalities, and the state to examine how social networks affect women's substance use in a rural Appalachian county where the primary drug of choice is prescription opioids. Of 503 participants...

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Buer LM, Leukefeld CG, Havens JR. "I'm Stuck": Women's Navigations of Social Networks and Prescription Drug Misuse in Central Appalachia. North Am Dialogue. 2016;19(2):70-84doi: 10.1111/nad.12044.
Buer, L. M., Leukefeld, C. G., & Havens, J. R. (2016). "I'm Stuck": Women's Navigations of Social Networks and Prescription Drug Misuse in Central Appalachia. North American dialogue : newsletter of the Society for the Anthropology of North America, 19(2), 70-84. https://doi.org/10.1111/nad.12044
Buer, Lesly-Marie, et al. ""I'm Stuck": Women's Navigations of Social Networks and Prescription Drug Misuse in Central Appalachia." North American dialogue : newsletter of the Society for the Anthropology of North America vol. 19,2 (2016): 70-84. doi: https://doi.org/10.1111/nad.12044
Buer LM, Leukefeld CG, Havens JR. "I'm Stuck": Women's Navigations of Social Networks and Prescription Drug Misuse in Central Appalachia. North Am Dialogue. 2016;19(2):70-84. doi: 10.1111/nad.12044. Epub 2016 Oct 28. PMID: 28736509; PMCID: PMC5519294.
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Showing 1 to 12 of 155 entries