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Showing 1 to 12 of 41 entries
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Natural history of Waldenström macroglobulinemia following acquired resistance to ibrutinib monotherapy.

Haematologica

Gustine JN, Sarosiek S, Flynn CA, Meid K, Leventoff C, White T, Guerrera ML, Xu L, Kofides A, Tsakmaklis N, Munshi M, Demos M, Patterson CJ, Liu X, Yang G, Hunter ZR, Branagan AR, Treon SP, Castillo JJ.
PMID: 34162182
Haematologica. 2021 Jun 24; doi: 10.3324/haematol.2021.279112. Epub 2021 Jun 24.

Ibrutinib is highly active and produces long-term responses in patients with Waldenström macroglobulinemia (WM), but acquired resistance can occur with prolonged treatment. We therefore evaluated the natural history and treatment outcomes in 51 WM patients with acquired resistance to...

Medical Management of Hemodynamically Unstable Sinoatrial Node Dysfunction in a Patient With Intracardiac Lymphoma.

JACC. CardioOncology

Martz CA, Jarbeau JF, Castillo JJ, Fisher DC, Nohria A.
PMID: 34396343
JACC CardioOncol. 2021 Jun 15;3(2):326-329. doi: 10.1016/j.jaccao.2021.03.003. eCollection 2021 Jun.

No abstract available.

How to Sequence Therapies in Waldenström Macroglobulinemia.

Current treatment options in oncology

Sarosiek S, Treon SP, Castillo JJ.
PMID: 34426943
Curr Treat Options Oncol. 2021 Aug 23;22(10):92. doi: 10.1007/s11864-021-00890-9.

OPINION STATEMENT: There are multiple treatment options in patients with Waldenström macroglobulinemia, including chemotherapy, monoclonal antibodies, proteasome inhibitors, and covalent Bruton tyrosine kinase (BTK) inhibitors. The choice of therapy should take into account the patient's clinical presentation, comorbidities, and...

Plasmablastic lymphoma transformation in a patient with Waldenström macroglobulinemia treated with ibrutinib.

British journal of haematology

Castillo JJ, LaMacchia J, Flynn CA, Sarosiek S, Pozdnyakova O, Treon SP.
PMID: 34355802
Br J Haematol. 2021 Nov;195(3):466-468. doi: 10.1111/bjh.17759. Epub 2021 Aug 06.

No abstract available.

POEMS Syndrome: Real World Experience in Diagnosis and Systemic Therapy - 108 Patients Multicenter Analysis.

Clinical lymphoma, myeloma & leukemia

Jurczyszyn A, Castillo JJ, Olszewska-Szopa M, Kumar L, Thibaud S, Richter J, Flicker K, Fiala M, Vij R, Yi S, Xu F, Silbermann R, Gaisan CM, Ocio EM, Waszczuk-Gajda A, Crusoe EQ, Salomon-Perzyński A, Hus I, Valls JD, Gozzetti A, Czepiel J, Krzanowska K, Chappell A, Chellapuram SK, Suska A, Vesole DH.
PMID: 34844892
Clin Lymphoma Myeloma Leuk. 2021 Oct 31; doi: 10.1016/j.clml.2021.10.007. Epub 2021 Oct 31.

POEMS syndrome, a rare plasma cell disorder, is challenging both in the diagnostic and therapeutic management. We present real word retrospective analysis of 108 cases analyzing clinical features and therapeutic modes. We compare our results with the available literature....

The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance.

Blood

Yang G, Wang J, Tan L, Munshi M, Liu X, Kofides A, Chen JG, Tsakmaklis N, Demos MG, Guerrera ML, Xu L, Hunter ZR, Che J, Patterson CJ, Meid K, Castillo JJ, Munshi NC, Anderson KC, Cameron M, Buhrlage SJ, Gray NS, Treon SP.
PMID: 34132782
Blood. 2021 Nov 18;138(20):1966-1979. doi: 10.1182/blood.2021011405.

Activating mutations in MYD88 promote malignant cell growth and survival through hematopoietic cell kinase (HCK)-mediated activation of Bruton tyrosine kinase (BTK). Ibrutinib binds to BTKCys481 and is active in B-cell malignancies driven by mutated MYD88. Mutations in BTKCys481, particularly...

Consensus Statement on the Management of Waldenström Macroglobulinemia Patients During the COVID-19 Pandemic.

HemaSphere

Talaulikar D, Advani RH, Branagan AR, Buske C, Dimopoulos MA, D'Sa S, Kersten MJ, Leblond V, Minnema MC, Owen RG, Palomba ML, Tedeschi A, Trotman J, Varettoni M, Vos JM, Treon SP, Kastritis E, Castillo JJ.
PMID: 32803133
Hemasphere. 2020 Jul 30;4(4):e433. doi: 10.1097/HS9.0000000000000433. eCollection 2020 Aug.

In the light of the COVID-19 pandemic, the International Workshop on Waldenström Macroglobulinemia (IWWM) Treatment Recommendations Panel felt the need to provide a consensus statement for the management of Waldenström Macroglobulinemia (WM) patients during this challenging time. We followed...

Do viscosity and wettability of fluoride varnishes affect their fluoride release?.

Journal of clinical and experimental dentistry

Asian J, Quenta E, Castillo JL.
PMID: 33680323
J Clin Exp Dent. 2021 Mar 01;13(3):e221-e226. doi: 10.4317/jced.56985. eCollection 2021 Mar.

BACKGROUND: There are several brands of fluoride varnishes in the market, but the dynamics of fluoride release from each one might be different. The purpose of this study was to evaluate in vitro the release of fluorides by fluoride...

What should be the goal of therapy for Waldenström macroglobulinemia patients? Complete response should be the goal of therapy.

Blood advances

Treon SP, Castillo JJ.
PMID: 29296899
Blood Adv. 2017 Nov 28;1(25):2486-2490. doi: 10.1182/bloodadvances.2017005637. eCollection 2017 Nov 28.

No abstract available.

Bonding failure is similar if brackets are bonded either with resin-modified glass ionomer cements (RM-GICs) or composite resin cements (CRCs).

The journal of evidence-based dental practice

Castillo JL.
PMID: 23177495
J Evid Based Dent Pract. 2012 Dec;12(4):193-5. doi: 10.1016/j.jebdp.2012.09.010.

No abstract available.

Long-term follow-up of ibrutinib monotherapy in treatment-naive patients with Waldenstrom macroglobulinemia.

Leukemia

Castillo JJ, Meid K, Gustine JN, Leventoff C, White T, Flynn CA, Sarosiek S, Demos MG, Guerrera ML, Kofides A, Liu X, Munshi M, Tsakmaklis N, Xu L, Yang G, Branagan AR, O'Donnell E, Raje N, Yee AJ, Patterson CJ, Hunter ZR, Treon SP.
PMID: 34531537
Leukemia. 2021 Sep 16; doi: 10.1038/s41375-021-01417-9. Epub 2021 Sep 16.

Herein, we present the final report of a single-center, prospective phase II study evaluating ibrutinib 420 mg once daily in 30 treatment-naive patients with Waldenstrom macroglobulinemia (WM). The present study is registered with ClinicalTrials.Gov (NCT02604511). With a median follow-up...

Effect of ibrutinib treatment on hemolytic anemia and acrocyanosis in cold agglutinin disease/cold agglutinin syndrome.

Blood

Jalink M, Berentsen S, Castillo JJ, Treon SP, Cruijsen M, Fattizzo B, Cassin R, Fotiou D, Kastritis E, De Haas M, Oosten LEM, Frederiksen H, Patriarca A, D'Sa S, Vos JMI.
PMID: 34293088
Blood. 2021 Nov 18;138(20):2002-2005. doi: 10.1182/blood.2021012039.

No abstract available.

Showing 1 to 12 of 41 entries