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Showing 1 to 12 of 19 entries
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Quantification of 99mTc-DPD concentration in the lumbar spine with SPECT/CT.

EJNMMI research

Cachovan M, Vija AH, Hornegger J, Kuwert T.
PMID: 23738809
EJNMMI Res. 2013 Jun 05;3(1):45. doi: 10.1186/2191-219X-3-45.

BACKGROUND: Routine single-photon emission computed tomography (SPECT) currently lacks quantitative information on regional activity concentration (ACC) of the injected tracer (e.g. kBq/ml). Furthermore, little is known on the skeletal absolute concentration of 99mTc-DPD after intravenous injection in bone scintigraphy....

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Cachovan M, Vija AH, Hornegger J, et al. Quantification of 99mTc-DPD concentration in the lumbar spine with SPECT/CT. EJNMMI Res. 2013;3(1):45doi: 10.1186/2191-219X-3-45.
Cachovan, M., Vija, A. H., Hornegger, J., & Kuwert, T. (2013). Quantification of 99mTc-DPD concentration in the lumbar spine with SPECT/CT. EJNMMI research, 3(1), 45. https://doi.org/10.1186/2191-219X-3-45
Cachovan, Michal, et al. "Quantification of 99mTc-DPD concentration in the lumbar spine with SPECT/CT." EJNMMI research vol. 3,1 (2013): 45. doi: https://doi.org/10.1186/2191-219X-3-45
Cachovan M, Vija AH, Hornegger J, Kuwert T. Quantification of 99mTc-DPD concentration in the lumbar spine with SPECT/CT. EJNMMI Res. 2013 Jun 05;3(1):45. doi: 10.1186/2191-219X-3-45. PMID: 23738809; PMCID: PMC3680030.
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The opposite effects of high-sucrose and high-fat diet on Fatty Acid oxidation and very low density lipoprotein secretion in rat model of metabolic syndrome.

Journal of nutrition and metabolism

Cahova M, Dankova H, Palenickova E, Papackova Z, Kazdova L.
PMID: 23125921
J Nutr Metab. 2012;2012:757205. doi: 10.1155/2012/757205. Epub 2012 Oct 17.

Aims. To determine the effect of two different diets (high-sucrose (HS) and high-fat (HF)) on the main metabolic pathways potentially contributing to the development of steatosis: (1) activity of the liver lysosomal and heparin-releasable lipases; (2) fatty acid (FFA)...

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Cahova M, Dankova H, Palenickova E, et al. The opposite effects of high-sucrose and high-fat diet on Fatty Acid oxidation and very low density lipoprotein secretion in rat model of metabolic syndrome. J Nutr Metab. 2012;2012:757205doi: 10.1155/2012/757205.
Cahova, M., Dankova, H., Palenickova, E., Papackova, Z., & Kazdova, L. (2012). The opposite effects of high-sucrose and high-fat diet on Fatty Acid oxidation and very low density lipoprotein secretion in rat model of metabolic syndrome. Journal of nutrition and metabolism, 2012757205. https://doi.org/10.1155/2012/757205
Cahova, Monika, et al. "The opposite effects of high-sucrose and high-fat diet on Fatty Acid oxidation and very low density lipoprotein secretion in rat model of metabolic syndrome." Journal of nutrition and metabolism vol. 2012 (2012): 757205. doi: https://doi.org/10.1155/2012/757205
Cahova M, Dankova H, Palenickova E, Papackova Z, Kazdova L. The opposite effects of high-sucrose and high-fat diet on Fatty Acid oxidation and very low density lipoprotein secretion in rat model of metabolic syndrome. J Nutr Metab. 2012;2012:757205. doi: 10.1155/2012/757205. Epub 2012 Oct 17. PMID: 23125921; PMCID: PMC3483727.
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Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study.

Multiple sclerosis (Houndmills, Basingstoke, England)

Bar-Or A, Wiendl H, Montalban X, Alvarez E, Davydovskaya M, Delgado SR, Evdoshenko EP, Giedraitiene N, Gross-Paju K, Haldre S, Herrman CE, Izquierdo G, Karelis G, Leutmezer F, Mares M, Meca-Lallana JE, Mickeviciene D, Nicholas J, Robertson DS, Sazonov DV, Sharlin K, Sundaram B, Totolyan N, Vachova M, Valis M, Bagger M, Häring DA, Ludwig I, Willi R, Zalesak M, Su W, Merschhemke M, Fox EJ.
PMID: 34605319
Mult Scler. 2021 Oct 04;13524585211044479. doi: 10.1177/13524585211044479. Epub 2021 Oct 04.

BACKGROUND: Ofatumumab, the first fully human anti-CD20 monoclonal antibody, is approved in several countries for relapsing multiple sclerosis (RMS).OBJECTIVE: To demonstrate the bioequivalence of ofatumumab administered by an autoinjector versus a pre-filled syringe (PFS) and to explore the effect...

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Bar-Or A, Wiendl H, Montalban X, et al. Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study. Mult Scler. 2021;13524585211044479doi: 10.1177/13524585211044479.
Bar-Or, A., Wiendl, H., Montalban, X., Alvarez, E., Davydovskaya, M., Delgado, S. R., Evdoshenko, E. P., Giedraitiene, N., Gross-Paju, K., Haldre, S., Herrman, C. E., Izquierdo, G., Karelis, G., Leutmezer, F., Mares, M., Meca-Lallana, J. E., Mickeviciene, D., Nicholas, J., Robertson, D. S., Sazonov, D. V., Sharlin, K., Sundaram, B., Totolyan, N., Vachova, M., Valis, M., Bagger, M., Häring, D. A., Ludwig, I., Willi, R., Zalesak, M., Su, W., Merschhemke, M., & Fox, E. J. (2021). Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study. Multiple sclerosis (Houndmills, Basingstoke, England), 13524585211044479. https://doi.org/10.1177/13524585211044479
Bar-Or, Amit, et al. "Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study." Multiple sclerosis (Houndmills, Basingstoke, England) vol. (2021): 13524585211044479. doi: https://doi.org/10.1177/13524585211044479
Bar-Or A, Wiendl H, Montalban X, Alvarez E, Davydovskaya M, Delgado SR, Evdoshenko EP, Giedraitiene N, Gross-Paju K, Haldre S, Herrman CE, Izquierdo G, Karelis G, Leutmezer F, Mares M, Meca-Lallana JE, Mickeviciene D, Nicholas J, Robertson DS, Sazonov DV, Sharlin K, Sundaram B, Totolyan N, Vachova M, Valis M, Bagger M, Häring DA, Ludwig I, Willi R, Zalesak M, Su W, Merschhemke M, Fox EJ. Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study. Mult Scler. 2021 Oct 04;13524585211044479. doi: 10.1177/13524585211044479. Epub 2021 Oct 04. PMID: 34605319.
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Accuracy comparison of various quantitative [.

EJNMMI research

Braun M, Cachovan M, Kaul F, Caobelli F, Bäumer M, Hans Vija A, Pagenstert G, Wild D, Kretzschmar M.
PMID: 34128128
EJNMMI Res. 2021 Jun 14;11(1):60. doi: 10.1186/s13550-021-00794-7.

BACKGROUND: There is a need for better diagnostic tools that identify loose total hip and knee arthroplasties. Here, we present the accuracy of different METHODS: Quantitative reconstruction of mineral phase SPECT data was performed using Siemens xSPECT-Quant and xSPECT-Bone,...

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Braun M, Cachovan M, Kaul F, et al. Accuracy comparison of various quantitative [. EJNMMI Res. 2021;11(1):60doi: 10.1186/s13550-021-00794-7.
Braun, M., Cachovan, M., Kaul, F., Caobelli, F., Bäumer, M., Hans Vija, A., Pagenstert, G., Wild, D., & Kretzschmar, M. (2021). Accuracy comparison of various quantitative [. EJNMMI research, 11(1), 60. https://doi.org/10.1186/s13550-021-00794-7
Braun, Martin, et al. "Accuracy comparison of various quantitative [." EJNMMI research vol. 11,1 (2021): 60. doi: https://doi.org/10.1186/s13550-021-00794-7
Braun M, Cachovan M, Kaul F, Caobelli F, Bäumer M, Hans Vija A, Pagenstert G, Wild D, Kretzschmar M. Accuracy comparison of various quantitative [. EJNMMI Res. 2021 Jun 14;11(1):60. doi: 10.1186/s13550-021-00794-7. PMID: 34128128; PMCID: PMC8203767.
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High satellite repeat turnover in great apes studied with short- and long-read technologies.

Molecular biology and evolution

Cechova M, Harris RS, Tomaszkiewicz M, Arbeithuber B, Chiaromonte F, Makova KD.
PMID: 31273383
Mol Biol Evol. 2019 Jul 02; doi: 10.1093/molbev/msz156. Epub 2019 Jul 02.

Satellite repeats are a structural component of centromeres and telomeres, and in some instances their divergence is known to drive speciation. Due to their highly repetitive nature, satellite sequences have been understudied and underrepresented in genome assemblies. To investigate...

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Cechova M, Harris RS, Tomaszkiewicz M, et al. High satellite repeat turnover in great apes studied with short- and long-read technologies. Mol Biol Evol. 2019;doi: 10.1093/molbev/msz156.
Cechova, M., Harris, R. S., Tomaszkiewicz, M., Arbeithuber, B., Chiaromonte, F., & Makova, K. D. (2019). High satellite repeat turnover in great apes studied with short- and long-read technologies. Molecular biology and evolution, . https://doi.org/10.1093/molbev/msz156
Cechova, Monika, et al. "High satellite repeat turnover in great apes studied with short- and long-read technologies." Molecular biology and evolution vol. (2019). doi: https://doi.org/10.1093/molbev/msz156
Cechova M, Harris RS, Tomaszkiewicz M, Arbeithuber B, Chiaromonte F, Makova KD. High satellite repeat turnover in great apes studied with short- and long-read technologies. Mol Biol Evol. 2019 Jul 02; doi: 10.1093/molbev/msz156. Epub 2019 Jul 02. PMID: 31273383; PMCID: PMC6805231.
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Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages.

Nutrition & metabolism

Papackova Z, Palenickova E, Dankova H, Zdychova J, Skop V, Kazdova L, Cahova M.
PMID: 22439764
Nutr Metab (Lond). 2012 Mar 22;9:22. doi: 10.1186/1743-7075-9-22.

BACKGROUND: Resident macrophages (Kupffer cells, KCs) in the liver can undergo both pro- or anti-inflammatory activation pathway and exert either beneficiary or detrimental effects on liver metabolism. Until now, their role in the metabolically dysfunctional state of steatosis remains...

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Papackova Z, Palenickova E, Dankova H, et al. Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages. Nutr Metab (Lond). 2012;9:22doi: 10.1186/1743-7075-9-22.
Papackova, Z., Palenickova, E., Dankova, H., Zdychova, J., Skop, V., Kazdova, L., & Cahova, M. (2012). Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages. Nutrition & metabolism, 922. https://doi.org/10.1186/1743-7075-9-22
Papackova, Zuzana, et al. "Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages." Nutrition & metabolism vol. 9 (2012): 22. doi: https://doi.org/10.1186/1743-7075-9-22
Papackova Z, Palenickova E, Dankova H, Zdychova J, Skop V, Kazdova L, Cahova M. Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages. Nutr Metab (Lond). 2012 Mar 22;9:22. doi: 10.1186/1743-7075-9-22. PMID: 22439764; PMCID: PMC3348013.
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The increased activity of liver lysosomal lipase in nonalcoholic Fatty liver disease contributes to the development of hepatic insulin resistance.

Biochemistry research international

Cahova M, Dankova H, Palenickova E, Papackova Z, Komers R, Zdychova J, Sticova E, Kazdova L.
PMID: 21904679
Biochem Res Int. 2012;2012:135723. doi: 10.1155/2012/135723. Epub 2011 Aug 23.

We tested the hypothesis that TAG accumulation in the liver induced by short-term high-fat diet (HFD) in rats leads to the dysregulation of endogenous TAG degradation by lysosomal lipase (LIPA) via lysosomal pathway and is causally linked with the...

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Cahova M, Dankova H, Palenickova E, et al. The increased activity of liver lysosomal lipase in nonalcoholic Fatty liver disease contributes to the development of hepatic insulin resistance. Biochem Res Int. 2011;2012:135723doi: 10.1155/2012/135723.
Cahova, M., Dankova, H., Palenickova, E., Papackova, Z., Komers, R., Zdychova, J., Sticova, E., & Kazdova, L. (2012). The increased activity of liver lysosomal lipase in nonalcoholic Fatty liver disease contributes to the development of hepatic insulin resistance. Biochemistry research international, 2012135723. https://doi.org/10.1155/2012/135723
Cahova, Monika, et al. "The increased activity of liver lysosomal lipase in nonalcoholic Fatty liver disease contributes to the development of hepatic insulin resistance." Biochemistry research international vol. 2012 (2012): 135723. doi: https://doi.org/10.1155/2012/135723
Cahova M, Dankova H, Palenickova E, Papackova Z, Komers R, Zdychova J, Sticova E, Kazdova L. The increased activity of liver lysosomal lipase in nonalcoholic Fatty liver disease contributes to the development of hepatic insulin resistance. Biochem Res Int. 2012;2012:135723. doi: 10.1155/2012/135723. Epub 2011 Aug 23. PMID: 21904679; PMCID: PMC3163129.
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Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Hruba E, Kavkova M, Dalecka L, Macholan M, Zikmund T, Varecha M, Bosakova M, Kaiser J, Krejci P, Hovorakova M, Buchtova M.
PMID: 34423857
J Bone Miner Res. 2021 Nov;36(11):2258-2274. doi: 10.1002/jbmr.4427. Epub 2021 Sep 20.

The Sprouty family is a highly conserved group of intracellular modulators of receptor tyrosine kinase (RTK)-signaling pathways, which have been recently linked to primary cilia. Disruptions in the structure and function of primary cilia cause inherited disorders called ciliopathies....

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Hruba E, Kavkova M, Dalecka L, et al. Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling. J Bone Miner Res. 2021;36(11):2258-2274doi: 10.1002/jbmr.4427.
Hruba, E., Kavkova, M., Dalecka, L., Macholan, M., Zikmund, T., Varecha, M., Bosakova, M., Kaiser, J., Krejci, P., Hovorakova, M., & Buchtova, M. (2021). Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 36(11), 2258-2274. https://doi.org/10.1002/jbmr.4427
Hruba, Eva, et al. "Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research vol. 36,11 (2021): 2258-2274. doi: https://doi.org/10.1002/jbmr.4427
Hruba E, Kavkova M, Dalecka L, Macholan M, Zikmund T, Varecha M, Bosakova M, Kaiser J, Krejci P, Hovorakova M, Buchtova M. Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling. J Bone Miner Res. 2021 Nov;36(11):2258-2274. doi: 10.1002/jbmr.4427. Epub 2021 Sep 20. PMID: 34423857.
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A Novel Approach to the Viability Determination of .

Frontiers in microbiology

Cechova M, Beinhauerova M, Babak V, Slana I, Kralik P.
PMID: 34899636
Front Microbiol. 2021 Nov 24;12:748337. doi: 10.3389/fmicb.2021.748337. eCollection 2021.

Mycobacterium avium subsp.

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Cechova M, Beinhauerova M, Babak V, et al. A Novel Approach to the Viability Determination of . Front Microbiol. 2021;12:748337doi: 10.3389/fmicb.2021.748337.
Cechova, M., Beinhauerova, M., Babak, V., Slana, I., & Kralik, P. (2021). A Novel Approach to the Viability Determination of . Frontiers in microbiology, 12748337. https://doi.org/10.3389/fmicb.2021.748337
Cechova, Martina, et al. "A Novel Approach to the Viability Determination of ." Frontiers in microbiology vol. 12 (2021): 748337. doi: https://doi.org/10.3389/fmicb.2021.748337
Cechova M, Beinhauerova M, Babak V, Slana I, Kralik P. A Novel Approach to the Viability Determination of . Front Microbiol. 2021 Nov 24;12:748337. doi: 10.3389/fmicb.2021.748337. eCollection 2021. PMID: 34899636; PMCID: PMC8652053.
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Gut Microbiota as the Link between Elevated BCAA Serum Levels and Insulin Resistance.

Biomolecules

Gojda J, Cahova M.
PMID: 34680047
Biomolecules. 2021 Sep 28;11(10). doi: 10.3390/biom11101414.

The microbiota-harboring human gut is an exquisitely active ecosystem that has evolved in a constant symbiosis with the human host. It produces numerous compounds depending on its metabolic capacity and substrates availability. Diet is the major source of the...

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Gojda J, Cahova M. Gut Microbiota as the Link between Elevated BCAA Serum Levels and Insulin Resistance. Biomolecules. 2021;11(10)doi: 10.3390/biom11101414.
Gojda, J., & Cahova, M. (2021). Gut Microbiota as the Link between Elevated BCAA Serum Levels and Insulin Resistance. Biomolecules, 11(10), . https://doi.org/10.3390/biom11101414
Gojda, Jan, and Cahova, Monika. "Gut Microbiota as the Link between Elevated BCAA Serum Levels and Insulin Resistance." Biomolecules vol. 11,10 (2021). doi: https://doi.org/10.3390/biom11101414
Gojda J, Cahova M. Gut Microbiota as the Link between Elevated BCAA Serum Levels and Insulin Resistance. Biomolecules. 2021 Sep 28;11(10). doi: 10.3390/biom11101414. PMID: 34680047; PMCID: PMC8533624.
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Diagnostic and prognostic value of placental growth factor serum concentration in clear cell renal cell carcinoma.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia

Cechova M, Chocholaty M, Babjuk M, Zima T, Havlova K, Koldova M, Schmidt M, Kalousova M.
PMID: 33612835
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021 Nov;165(4):375-379. doi: 10.5507/bp.2021.003. Epub 2021 Feb 22.

BACKGROUND AND AIM: Placental Growth Factor (PlGF) plays a crucial role in angiogenesis and was identified as a potential prognostic biomarker in various types of cancer. Therefore, we evaluated the diagnostic accuracy and prognostic value of PlGF serum concentration...

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Cechova M, Chocholaty M, Babjuk M, et al. Diagnostic and prognostic value of placental growth factor serum concentration in clear cell renal cell carcinoma. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021;165(4):375-379doi: 10.5507/bp.2021.003.
Cechova, M., Chocholaty, M., Babjuk, M., Zima, T., Havlova, K., Koldova, M., Schmidt, M., & Kalousova, M. (2021). Diagnostic and prognostic value of placental growth factor serum concentration in clear cell renal cell carcinoma. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 165(4), 375-379. https://doi.org/10.5507/bp.2021.003
Cechova, Marcela, et al. "Diagnostic and prognostic value of placental growth factor serum concentration in clear cell renal cell carcinoma." Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia vol. 165,4 (2021): 375-379. doi: https://doi.org/10.5507/bp.2021.003
Cechova M, Chocholaty M, Babjuk M, Zima T, Havlova K, Koldova M, Schmidt M, Kalousova M. Diagnostic and prognostic value of placental growth factor serum concentration in clear cell renal cell carcinoma. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021 Nov;165(4):375-379. doi: 10.5507/bp.2021.003. Epub 2021 Feb 22. PMID: 33612835.
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Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages.

Nutrition & metabolism

Papackova Z, Palenickova E, Dankova H, Zdychova J, Skop V, Kazdova L, Cahova M.
PMID: 22439764
Nutr Metab (Lond). 2012 Mar 22;9:22. doi: 10.1186/1743-7075-9-22.

BACKGROUND: Resident macrophages (Kupffer cells, KCs) in the liver can undergo both pro- or anti-inflammatory activation pathway and exert either beneficiary or detrimental effects on liver metabolism. Until now, their role in the metabolically dysfunctional state of steatosis remains...

Cite
Papackova Z, Palenickova E, Dankova H, et al. Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages. Nutr Metab (Lond). 2012;9:22doi: 10.1186/1743-7075-9-22.
Papackova, Z., Palenickova, E., Dankova, H., Zdychova, J., Skop, V., Kazdova, L., & Cahova, M. (2012). Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages. Nutrition & metabolism, 922. https://doi.org/10.1186/1743-7075-9-22
Papackova, Zuzana, et al. "Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages." Nutrition & metabolism vol. 9 (2012): 22. doi: https://doi.org/10.1186/1743-7075-9-22
Papackova Z, Palenickova E, Dankova H, Zdychova J, Skop V, Kazdova L, Cahova M. Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages. Nutr Metab (Lond). 2012 Mar 22;9:22. doi: 10.1186/1743-7075-9-22. PMID: 22439764; PMCID: PMC3348013.
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