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Showing 1 to 12 of 308 entries
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Taking professional development from 2D to 3D: Design-based learning, 2D modeling, and 3D fabrication for authentic standards-aligned lesson plans

lesson plans

Cairns DR, Curtis R, Sierros KA.
GSID: V0zu3ly5xRQJ
DR Cairns, R Curtis, KA Sierros… - … interdisciplinary journal of …, 2018 - ncbi.nlm.nih.gov

… We believe that 3D printing can be incorporated into engineering design lesson plans that provide rich authentic contexts in which students can experience deep learning. We also believe that if these lesson plans are carefully constructed, they can...

miRNA Enriched in Human Neuroblast Nuclei Bind the MAZ Transcription Factor and Their Precursors Contain the MAZ Consensus Motif.

Frontiers in molecular neuroscience

Goldie BJ, Fitzsimmons C, Weidenhofer J, Atkins JR, Wang DO, Cairns MJ.
PMID: 28878619
Front Mol Neurosci. 2017 Aug 21;10:259. doi: 10.3389/fnmol.2017.00259. eCollection 2017.

While the cytoplasmic function of microRNA (miRNA) as post-transcriptional regulators of mRNA has been the subject of significant research effort, their activity in the nucleus is less well characterized. Here we use a human neuronal cell model to show...

Selective repression of SINE transcription by RNA polymerase III.

Mobile genetic elements

Varshney D, Vavrova-Anderson J, Oler AJ, Cairns BR, White RJ.
PMID: 26942044
Mob Genet Elements. 2015 Sep 23;5(6):86-91. doi: 10.1080/2159256X.2015.1096997. eCollection 2015.

A million copies of the Alu short interspersed nuclear element (SINE) are scattered throughout the human genome, providing ∼11% of our total DNA. SINEs spread by retrotransposition, using a transcript generated by RNA polymerase (pol) III from an internal...

Correction for Cairns et al., "Comparative Genome Analysis and Global Phylogeny of the Toxin Variant Clostridium difficile PCR Ribotype 017 Reveals the Evolution of Two Independent Sublineages".

Journal of clinical microbiology

Cairns MD, Preston MD, Hall CL, Gerding DN, Hawkey PM, Kato H, Kim H, Kuijper EJ, Lawley TD, Pituch H, Reid S, Kullin B, Riley TV, Solomon K, Tsai PJ, Weese JS, Stabler RA, Wren BW.
PMID: 28536162
J Clin Microbiol. 2017 Jun;55(6):1971. doi: 10.1128/JCM.00487-17.

No abstract available.

Quantifying the impact of inter-site heterogeneity on the distribution of ChIP-seq data.

Frontiers in genetics

Cairns J, Lynch AG, Tavaré S.
PMID: 25452765
Front Genet. 2014 Nov 14;5:399. doi: 10.3389/fgene.2014.00399. eCollection 2014.

Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) is a valuable tool for epigenetic studies. Analysis of the data arising from ChIP-seq experiments often requires implicit or explicit statistical modeling of the read counts. The simple Poisson model is attractive, but...

Tunable Rare Earth fcu-MOF Platform: Access to Adsorption Kinetics Driven Gas/Vapor Separations via Pore Size Contraction.

Journal of the American Chemical Society

Xue DX, Belmabkhout Y, Shekhah O, Jiang H, Adil K, Cairns AJ, Eddaoudi M.
PMID: 25825923
J Am Chem Soc. 2015 Apr 22;137(15):5034-40. doi: 10.1021/ja5131403. Epub 2015 Apr 10.

Reticular chemistry approach was successfully employed to deliberately construct new rare-earth (RE, i.e., Eu(3+), Tb(3+), and Y(3+)) fcu metal-organic frameworks (MOFs) with restricted window apertures. Controlled and selective access to the resultant contracted fcu-MOF pores permits the achievement of...

Potential of metal-organic frameworks for separation of xenon and krypton.

Accounts of chemical research

Banerjee D, Cairns AJ, Liu J, Motkuri RK, Nune SK, Fernandez CA, Krishna R, Strachan DM, Thallapally PK.
PMID: 25479165
Acc Chem Res. 2015 Feb 17;48(2):211-9. doi: 10.1021/ar5003126. Epub 2014 Dec 05.

CONSPECTUS: The total world energy demand is predicted to rise significantly over the next few decades, primarily driven by the continuous growth of the developing world. With rapid depletion of nonrenewable traditional fossil fuels, which currently account for almost...

Fructan synthesis, accumulation and polymer traits. II. Fructan pools in populations of perennial ryegrass (Lolium perenne L.) with variation for water-soluble carbohydrate and candidate genes were not correlated with biosynthetic activity and demonstrated constraints to polymer chain extension.

Frontiers in plant science

Gallagher JA, Cairns AJ, Thomas D, Timms-Taravella E, Skøt K, Charlton A, Williams P, Turner LB.
PMID: 26528321
Front Plant Sci. 2015 Oct 15;6:864. doi: 10.3389/fpls.2015.00864. eCollection 2015.

Differences have been shown between ryegrass and fescue within the Festulolium subline introgression family for fructan synthesis, metabolism, and polymer-size traits. It is well-established that there is considerable variation for water-soluble carbohydrate and fructan content within perennial ryegrass. However...

Synthesis of an azido-tagged low affinity ratiometric calcium sensor.

Tetrahedron

Caldwell ST, Cairns AG, Olson M, Chalmers S, Sandison M, Mullen W, McCarron JG, Hartley RC.
PMID: 26709317
Tetrahedron. 2015 Dec 23;71(51):9571-9578. doi: 10.1016/j.tet.2015.10.052.

Changes in high localised concentrations of Ca

The spatial patterns of pathological brain lesions in 12 patients with corticobasal degeneration.

Pathophysiology : the official journal of the International Society for Pathophysiology

Armstrong RA, Lantos PL, Cairns NJ.
PMID: 11476973
Pathophysiology. 2001 Aug;8(1):47-53. doi: 10.1016/s0928-4680(00)00060-2.

Corticobasal degeneration (CBD) is a rare and progressive neurological disorder characterised by the presence of ballooned neurons (BN) and tau positive inclusions in neurons and glial cells. We studied the spatial patterns of the BN, tau positive neurons with...

Should health screening be private? .

BMJ (Clinical research ed.)

Cairns J.
PMID: 10346797
BMJ. 1999 May 29;318(7196):1494A. doi: 10.1136/bmj.318.7196.1494a.

No abstract available.

Rhythm control and rate control did not differ for CV mortality in atrial fibrillation and congestive heart failure.

ACP journal club

Cairns J.
PMID: 18937386
ACP J Club. 2008 Nov-Dec;149(4):8.

No abstract available.

Showing 1 to 12 of 308 entries