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Showing 1 to 12 of 31 entries
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Prognostic Value of Routinely Measured Inflammatory Biomarkers in Older Cancer Patients: Pooled Analysis of Three Cohorts.

Cancers

Oubaya N, Soubeyran P, Reinald N, Fonck M, Allain M, Zebachi S, Heitz D, Laurent M, Delattre C, Caillet P, Dauba J, Bastuji-Garin S, Albrand G, Bringuier M, Rainfray M, Brain E, Grellety T, Paillaud E, Mathoulin-Pélissier S, Bellera C, Canouï-Poitrine F.
PMID: 34944774
Cancers (Basel). 2021 Dec 07;13(24). doi: 10.3390/cancers13246154.

BACKGROUND: The prognostic assessment of older cancer patients is complicated by their heterogeneity. We aimed to assess the prognostic value of routine inflammatory biomarkers.METHODS: A pooled analysis of prospective multicenter cohorts of cancer patients aged ≥70 was performed. We...

Prognostic Value of Routinely Measured Inflammatory Biomarkers in Older Cancer Patients: Pooled Analysis of Three Cohorts.

Cancers

Oubaya N, Soubeyran P, Reinald N, Fonck M, Allain M, Zebachi S, Heitz D, Laurent M, Delattre C, Caillet P, Dauba J, Bastuji-Garin S, Albrand G, Bringuier M, Rainfray M, Brain E, Grellety T, Paillaud E, Mathoulin-Pélissier S, Bellera C, Canouï-Poitrine F.
PMID: 34944774
Cancers (Basel). 2021 Dec 07;13(24). doi: 10.3390/cancers13246154.

BACKGROUND: The prognostic assessment of older cancer patients is complicated by their heterogeneity. We aimed to assess the prognostic value of routine inflammatory biomarkers.METHODS: A pooled analysis of prospective multicenter cohorts of cancer patients aged ≥70 was performed. We...

Frailty Parameters, Morbidity and Mortality in Older Adults with Cancer: A Structural Equation Modelling Approach Based on the Fried Phenotype.

Journal of clinical medicine

Pamoukdjian F, Laurent M, Martinez-Tapia C, Rolland Y, Paillaud E, Canoui-Poitrine F.
PMID: 32545298
J Clin Med. 2020 Jun 11;9(6). doi: 10.3390/jcm9061826.

BACKGROUND: to distinguish direct and indirect pathways to frailty phenotype, and quantify associations between two frailty components (i.e., sarcopenia and cachexia) regarding mortality and morbidity in older adults with cancer.METHODS: all consecutive older outpatients with cancer were included in...

The obesity paradox for mid- and long-term mortality in older cancer patients: a prospective multicenter cohort study.

The American journal of clinical nutrition

Martinez-Tapia C, Diot T, Oubaya N, Paillaud E, Poisson J, Gisselbrecht M, Morisset L, Caillet P, Baudin A, Pamoukdjian F, Broussier A, Bastuji-Garin S, Laurent M, Canouï-Poitrine F.
PMID: 32889525
Am J Clin Nutr. 2020 Sep 05; doi: 10.1093/ajcn/nqaa238. Epub 2020 Sep 05.

BACKGROUND: Overweight and obesity are associated with adverse health outcomes. However, substantial literature suggests that they are associated with longer survival among older people. This "obesity paradox" remains controversial. In the context of cancer, the association between overweight/obesity and...

Clinical Characteristics, Care Trajectories and Mortality Rate of SARS-CoV-2 Infected Cancer Patients: A Multicenter Cohort Study.

Cancers

Benderra MA, Aparicio A, Leblanc J, Wassermann D, Kempf E, Galula G, Bernaux M, Canellas A, Moreau T, Bellamine A, Spano JP, Daniel C, Champ J, Canouï-Poitrine F, Gligorov J, On Behalf Of The Ap-Hp/Universities/Inserm Covid-Research Collaboration, Cancer Ap-Hp Group Covid-Task Force, Ap-Hp Covid Cdw Initiative Acci.
PMID: 34638235
Cancers (Basel). 2021 Sep 23;13(19). doi: 10.3390/cancers13194749.

BACKGROUND: COVID-19 may be more frequent and more severe in cancer patients than in other individuals. Our aims were to assess the rate of COVID-19 in hospitalized cancer patients, to describe their demographic characteristics, clinical features and care trajectories,...

Myosteatosis as an independent risk factor for mortality after kidney allograft transplantation: a retrospective cohort study.

Journal of cachexia, sarcopenia and muscle

Morel A, Ouamri Y, Canouï-Poitrine F, Mulé S, Champy CM, Ingels A, Audard V, Luciani A, Grimbert P, Matignon M, Pigneur F, Stehlé T.
PMID: 34738343
J Cachexia Sarcopenia Muscle. 2021 Nov 05; doi: 10.1002/jcsm.12853. Epub 2021 Nov 05.

BACKGROUND: Patients with end-stage renal disease may display both a loss of skeletal muscle mass and an increase in muscle fat deposits. We aimed to analyse the impact of low skeletal muscle mass index (SMI, surrogate marker of sarcopenia)...

Factors Associated With Aggressiveness of End-of-Life Care for Lung Cancer Patients and Associated Costs of Care.

Clinical lung cancer

Bylicki O, Rivière F, Tournier C, Canoui-Poitrine F, Grassin F, Margery J, Prodel M, Vainchtock A, Assié JB, Chouaïd C.
PMID: 32646653
Clin Lung Cancer. 2021 May;22(3):e320-e328. doi: 10.1016/j.cllc.2020.05.017. Epub 2020 May 23.

BACKGROUND: Results of previous studies demonstrated that high-intensity end-of-life (EOL) care improves neither cancer patients' survival nor quality of life. Our objective was to assess the incidence of and factors associated with aggressiveness of care during the last 30...

Creatinine clearance after cimetidine administration in a new short procedure: comparison with plasma and renal clearances of iohexol.

Clinical kidney journal

Stehlé T, El Karoui K, Sakka M, Ismail A, Matignon M, Grimbert P, Canoui-Poitrine F, Prié D, Audard V.
PMID: 32905173
Clin Kidney J. 2019 Jul 21;13(4):587-596. doi: 10.1093/ckj/sfz087. eCollection 2020 Aug.

BACKGROUND: Creatinine clearance after cimetidine administration (Cim-CreatClr) was once proposed as a method of glomerular filtration rate (GFR) measurement, but has been largely abandoned. We investigated whether a new short procedure for Cim-CreatClr determination could be considered an appropriate...

mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants.

Immunity

Sokal A, Barba-Spaeth G, Fernández I, Broketa M, Azzaoui I, de La Selle A, Vandenberghe A, Fourati S, Roeser A, Meola A, Bouvier-Alias M, Crickx E, Languille L, Michel M, Godeau B, Gallien S, Melica G, Nguyen Y, Zarrouk V, Canoui-Poitrine F, Pirenne F, Mégret J, Pawlotsky JM, Fillatreau S, Bruhns P, Rey FA, Weill JC, Reynaud CA, Chappert P, Mahévas M.
PMID: 34614412
Immunity. 2021 Sep 21; doi: 10.1016/j.immuni.2021.09.011. Epub 2021 Sep 21.

In addition to serum immunoglobulins, memory B cell (MBC) generation against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is another layer of immune protection, but the quality of MBC responses in naive and coronavirus disease 2019 (COVID-19)-recovered individuals after...

Long-term quality of life in necrotizing soft-tissue infection survivors: a monocentric prospective cohort study.

Annals of intensive care

Urbina T, Canoui-Poitrine F, Hua C, Layese R, Alves A, Ouedraogo R, Bosc R, Sbidian E, Chosidow O, Dessap AM, de Prost N.
PMID: 34213694
Ann Intensive Care. 2021 Jul 02;11(1):102. doi: 10.1186/s13613-021-00891-9.

BACKGROUND: Compared to other life-threatening infection survivors, long-term health-related quality of life (QOL) of patients surviving necrotizing soft-tissue infections (NSTI) and its determinants are little known. In this monocentric prospective cohort including NSTI survivors admitted between 2014 and 2017,...

Should We Quantify Valvular Calcifications on Cardiac CT in Patients with Infective Endocarditis?.

Journal of clinical medicine

Chevance V, Valter R, Nouri MR, Sifaoui I, Moussafeur A, Lepeule R, Bergoend E, Mule S, Tacher V, Huguet R, Folliguet T, Canoui-Poitrine F, Lim P, Deux JF.
PMID: 34640477
J Clin Med. 2021 Sep 28;10(19). doi: 10.3390/jcm10194458.

BACKGROUND: Evaluate the impact of valvular calcifications measured on cardiac computed tomography (CCT) in patients with infective endocarditis (IE).METHODS: Seventy patients with native IE (36 aortic IE, 31 mitral IE, 3 bivalvular IE) were included and explored with CCT...

Effect of lockdown on digestive system cancer care amongst older patients during the first wave of COVID-19: The CADIGCOVAGE multicentre cohort study.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Aparicio T, Layese R, Hemery F, Tournigand C, Paillaud E, De Angelis N, Quero L, Ganne N, Prat F, Pachev A, Galula G, Benderra MA, Canouï-Poitrine F.
PMID: 34654679
Dig Liver Dis. 2021 Oct 04; doi: 10.1016/j.dld.2021.09.017. Epub 2021 Oct 04.

BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has had a dramatic impact on cancer diagnosis and treatment. Most patients newly diagnosed with digestive system cancer are aged 65 and over.METHODS: We performed a retrospective, observational, multicentre cohort study based...

Showing 1 to 12 of 31 entries