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Encapsulation of labile trivalent lanthanides into a homobimetallic chromium(III)-containing triple-stranded helicate. Synthesis, characterization, and divergent intramolecular energy transfers.

Dalton transactions (Cambridge, England : 2003)

Cantuel M, Gumy F, Bünzli JC, Piguet C.
PMID: 16804577
Dalton Trans. 2006 Jun 14;(22):2647-60. doi: 10.1039/b602392d. Epub 2006 Apr 04.

The segmental bidentate-tridentate-bidentate ligand L2 reacts with M(II) (M = Cr, Zn) and Ln(III) (Ln = La, Eu, Gd, Tb, Lu) to give the heterotrimetallic triple-stranded helicates [MLnM(L2)3]7+. For M = Zn(II), the isolated complexes [ZnLnZn(L2)3](CF3SO3)7 (Ln = Eu,...

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Cantuel M, Gumy F, Bünzli JC, et al. Encapsulation of labile trivalent lanthanides into a homobimetallic chromium(III)-containing triple-stranded helicate. Synthesis, characterization, and divergent intramolecular energy transfers. Dalton Trans. 2006;(22):2647-60doi: 10.1039/b602392d.
Cantuel, M., Gumy, F., Bünzli, J. C., & Piguet, C. (2006). Encapsulation of labile trivalent lanthanides into a homobimetallic chromium(III)-containing triple-stranded helicate. Synthesis, characterization, and divergent intramolecular energy transfers. Dalton transactions (Cambridge, England : 2003), (22), 2647-60. https://doi.org/10.1039/b602392d
Cantuel, Martine, et al. "Encapsulation of labile trivalent lanthanides into a homobimetallic chromium(III)-containing triple-stranded helicate. Synthesis, characterization, and divergent intramolecular energy transfers." Dalton transactions (Cambridge, England : 2003) vol. ,22 (2006): 2647-60. doi: https://doi.org/10.1039/b602392d
Cantuel M, Gumy F, Bünzli JC, Piguet C. Encapsulation of labile trivalent lanthanides into a homobimetallic chromium(III)-containing triple-stranded helicate. Synthesis, characterization, and divergent intramolecular energy transfers. Dalton Trans. 2006 Jun 14;(22):2647-60. doi: 10.1039/b602392d. Epub 2006 Apr 04. PMID: 16804577.
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Spontaneous formation of fluorescent nanofibers and reticulated solid from berberine palmitate: a new example of aggregation-induced emission enhancement in organic ion pairs.

Langmuir : the ACS journal of surfaces and colloids

Chahine J, Saffon N, Cantuel M, Fery-Forgues S.
PMID: 21338124
Langmuir. 2011 Mar 15;27(6):2844-53. doi: 10.1021/la104302d. Epub 2011 Feb 22.

The salt formed between the large aromatic berberine cation and the long-chain palmitate anion was synthesized and used to prepare aqueous suspensions of particles owing to a solvent-exchange method. Under these conditions, elongated particles were readily obtained. They were...

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Chahine J, Saffon N, Cantuel M, et al. Spontaneous formation of fluorescent nanofibers and reticulated solid from berberine palmitate: a new example of aggregation-induced emission enhancement in organic ion pairs. Langmuir. 2011;27(6):2844-53doi: 10.1021/la104302d.
Chahine, J., Saffon, N., Cantuel, M., & Fery-Forgues, S. (2011). Spontaneous formation of fluorescent nanofibers and reticulated solid from berberine palmitate: a new example of aggregation-induced emission enhancement in organic ion pairs. Langmuir : the ACS journal of surfaces and colloids, 27(6), 2844-53. https://doi.org/10.1021/la104302d
Chahine, Joe, et al. "Spontaneous formation of fluorescent nanofibers and reticulated solid from berberine palmitate: a new example of aggregation-induced emission enhancement in organic ion pairs." Langmuir : the ACS journal of surfaces and colloids vol. 27,6 (2011): 2844-53. doi: https://doi.org/10.1021/la104302d
Chahine J, Saffon N, Cantuel M, Fery-Forgues S. Spontaneous formation of fluorescent nanofibers and reticulated solid from berberine palmitate: a new example of aggregation-induced emission enhancement in organic ion pairs. Langmuir. 2011 Mar 15;27(6):2844-53. doi: 10.1021/la104302d. Epub 2011 Feb 22. PMID: 21338124.
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Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose.

Frontiers in genetics

Canouil M, Balkau B, Roussel R, Froguel P, Rocheleau G.
PMID: 29963075
Front Genet. 2018 Jun 14;9:210. doi: 10.3389/fgene.2018.00210. eCollection 2018.

In observational cohorts, longitudinal data are collected with repeated measurements at predetermined time points for many biomarkers, along with other variables measured at baseline. In these cohorts, time until a certain event of interest occurs is reported and very...

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Canouil M, Balkau B, Roussel R, et al. Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose. Front Genet. 2018;9:210doi: 10.3389/fgene.2018.00210.
Canouil, M., Balkau, B., Roussel, R., Froguel, P., & Rocheleau, G. (2018). Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose. Frontiers in genetics, 9210. https://doi.org/10.3389/fgene.2018.00210
Canouil, Mickaël, et al. "Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose." Frontiers in genetics vol. 9 (2018): 210. doi: https://doi.org/10.3389/fgene.2018.00210
Canouil M, Balkau B, Roussel R, Froguel P, Rocheleau G. Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose. Front Genet. 2018 Jun 14;9:210. doi: 10.3389/fgene.2018.00210. eCollection 2018. PMID: 29963075; PMCID: PMC6010582.
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Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion.

Cell reports

Hu M, Cebola I, Carrat G, Jiang S, Nawaz S, Khamis A, Canouil M, Froguel P, Schulte A, Solimena M, Ibberson M, Marchetti P, Cardenas-Diaz FL, Gadue PJ, Hastoy B, Almeida-Souza L, McMahon H, Rutter GA.
PMID: 33535042
Cell Rep. 2021 Feb 02;34(5):108703. doi: 10.1016/j.celrep.2021.108703.

Using chromatin conformation capture, we show that an enhancer cluster in the STARD10 type 2 diabetes (T2D) locus forms a defined 3-dimensional (3D) chromatin domain. A 4.1-kb region within this locus, carrying 5 T2D-associated variants, physically interacts with CTCF-binding...

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Hu M, Cebola I, Carrat G, et al. Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion. Cell Rep. 2021;34(5):108703doi: 10.1016/j.celrep.2021.108703.
Hu, M., Cebola, I., Carrat, G., Jiang, S., Nawaz, S., Khamis, A., Canouil, M., Froguel, P., Schulte, A., Solimena, M., Ibberson, M., Marchetti, P., Cardenas-Diaz, F. L., Gadue, P. J., Hastoy, B., Almeida-Souza, L., McMahon, H., & Rutter, G. A. (2021). Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion. Cell reports, 34(5), 108703. https://doi.org/10.1016/j.celrep.2021.108703
Hu, Ming, et al. "Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion." Cell reports vol. 34,5 (2021): 108703. doi: https://doi.org/10.1016/j.celrep.2021.108703
Hu M, Cebola I, Carrat G, Jiang S, Nawaz S, Khamis A, Canouil M, Froguel P, Schulte A, Solimena M, Ibberson M, Marchetti P, Cardenas-Diaz FL, Gadue PJ, Hastoy B, Almeida-Souza L, McMahon H, Rutter GA. Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion. Cell Rep. 2021 Feb 02;34(5):108703. doi: 10.1016/j.celrep.2021.108703. PMID: 33535042; PMCID: PMC7856552.
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Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants.

ACS pharmacology & translational science

Hegron A, Huh E, Deupi X, Sokrat B, Gao W, Le Gouill C, Canouil M, Boissel M, Charpentier G, Roussel R, Balkau B, Froguel P, Plouffe B, Bonnefond A, Lichtarge O, Jockers R, Bouvier M.
PMID: 34661078
ACS Pharmacol Transl Sci. 2021 Sep 01;4(5):1614-1627. doi: 10.1021/acsptsci.1c00157. eCollection 2021 Oct 08.

Melatonin is a hormone mainly produced by the pineal gland and MT

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Hegron A, Huh E, Deupi X, et al. Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants. ACS Pharmacol Transl Sci. 2021;4(5):1614-1627doi: 10.1021/acsptsci.1c00157.
Hegron, A., Huh, E., Deupi, X., Sokrat, B., Gao, W., Le Gouill, C., Canouil, M., Boissel, M., Charpentier, G., Roussel, R., Balkau, B., Froguel, P., Plouffe, B., Bonnefond, A., Lichtarge, O., Jockers, R., & Bouvier, M. (2021). Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants. ACS pharmacology & translational science, 4(5), 1614-1627. https://doi.org/10.1021/acsptsci.1c00157
Hegron, Alan, et al. "Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants." ACS pharmacology & translational science vol. 4,5 (2021): 1614-1627. doi: https://doi.org/10.1021/acsptsci.1c00157
Hegron A, Huh E, Deupi X, Sokrat B, Gao W, Le Gouill C, Canouil M, Boissel M, Charpentier G, Roussel R, Balkau B, Froguel P, Plouffe B, Bonnefond A, Lichtarge O, Jockers R, Bouvier M. Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants. ACS Pharmacol Transl Sci. 2021 Sep 01;4(5):1614-1627. doi: 10.1021/acsptsci.1c00157. eCollection 2021 Oct 08. PMID: 34661078; PMCID: PMC8507577.
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The first enantiomerically pure helical noncovalent tripod for assembling nine-coordinate lanthanide(III) podates.

Inorganic chemistry

Cantuel M, Bernardinelli G, Muller G, Riehl JP, Piguet C.
PMID: 15018502
Inorg Chem. 2004 Mar 22;43(6):1840-9. doi: 10.1021/ic035292u.

Decomplexation of the trivalent lanthanide, Ln(III), from the racemic bimetallic triple-stranded helicates [LnCr(L8)(3)](6+) provides the inert chiral tripodal nonadentate receptor [Cr(L8)(3)](3+). Elution of the latter podand with Na(2)Sb(2)[(+)-C(4)O(6)H(2)](2).5H(2)O through a cation exchange column allows its separation into its inert...

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Cantuel M, Bernardinelli G, Muller G, et al. The first enantiomerically pure helical noncovalent tripod for assembling nine-coordinate lanthanide(III) podates. Inorg Chem. 2004;43(6):1840-9doi: 10.1021/ic035292u.
Cantuel, M., Bernardinelli, G., Muller, G., Riehl, J. P., & Piguet, C. (2004). The first enantiomerically pure helical noncovalent tripod for assembling nine-coordinate lanthanide(III) podates. Inorganic chemistry, 43(6), 1840-9. https://doi.org/10.1021/ic035292u
Cantuel, Martine, et al. "The first enantiomerically pure helical noncovalent tripod for assembling nine-coordinate lanthanide(III) podates." Inorganic chemistry vol. 43,6 (2004): 1840-9. doi: https://doi.org/10.1021/ic035292u
Cantuel M, Bernardinelli G, Muller G, Riehl JP, Piguet C. The first enantiomerically pure helical noncovalent tripod for assembling nine-coordinate lanthanide(III) podates. Inorg Chem. 2004 Mar 22;43(6):1840-9. doi: 10.1021/ic035292u. PMID: 15018502.
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Palliative Care in SMA Type 1: A Prospective Multicenter French Study Based on Parents' Reports.

Frontiers in pediatrics

Hully M, Barnerias C, Chabalier D, Le Guen S, Germa V, Deladriere E, Vanhulle C, Cuisset JM, Chabrol B, Cances C, Vuillerot C, Espil C, Mayer M, Nougues MC, Sabouraud P, Lefranc J, Laugel V, Rivier F, Louvier UW, Durigneux J, Napuri S, Sarret C, Renouil M, Masurel A, Viallard ML, Desguerre I.
PMID: 32133329
Front Pediatr. 2020 Feb 18;8:4. doi: 10.3389/fped.2020.00004. eCollection 2020.

Spinal muscular atrophy type 1 (SMA-1) is a severe neurodegenerative disorder, which in the absence of curative treatment, leads to death before 1 year of age in most cases. Caring for these short-lived and severely impaired infants requires palliative...

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Hully M, Barnerias C, Chabalier D, et al. Palliative Care in SMA Type 1: A Prospective Multicenter French Study Based on Parents' Reports. Front Pediatr. 2020;8:4doi: 10.3389/fped.2020.00004.
Hully, M., Barnerias, C., Chabalier, D., Le Guen, S., Germa, V., Deladriere, E., Vanhulle, C., Cuisset, J. M., Chabrol, B., Cances, C., Vuillerot, C., Espil, C., Mayer, M., Nougues, M. C., Sabouraud, P., Lefranc, J., Laugel, V., Rivier, F., Louvier, U. W., Durigneux, J., Napuri, S., Sarret, C., Renouil, M., Masurel, A., Viallard, M. L., & Desguerre, I. (2020). Palliative Care in SMA Type 1: A Prospective Multicenter French Study Based on Parents' Reports. Frontiers in pediatrics, 84. https://doi.org/10.3389/fped.2020.00004
Hully, Marie, et al. "Palliative Care in SMA Type 1: A Prospective Multicenter French Study Based on Parents' Reports." Frontiers in pediatrics vol. 8 (2020): 4. doi: https://doi.org/10.3389/fped.2020.00004
Hully M, Barnerias C, Chabalier D, Le Guen S, Germa V, Deladriere E, Vanhulle C, Cuisset JM, Chabrol B, Cances C, Vuillerot C, Espil C, Mayer M, Nougues MC, Sabouraud P, Lefranc J, Laugel V, Rivier F, Louvier UW, Durigneux J, Napuri S, Sarret C, Renouil M, Masurel A, Viallard ML, Desguerre I. Palliative Care in SMA Type 1: A Prospective Multicenter French Study Based on Parents' Reports. Front Pediatr. 2020 Feb 18;8:4. doi: 10.3389/fped.2020.00004. eCollection 2020. PMID: 32133329; PMCID: PMC7039815.
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Correction to: In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study.

BMC medicine

Sermet-Gaudelus I, Renouil M, Fajac A, Bidou L, Parbaille B, Pierrot S, Davy N, Bismuth E, Reinert P, Lenoir G, Lesure JF, Rousset JP, Edelman A.
PMID: 30143037
BMC Med. 2018 Aug 25;16(1):159. doi: 10.1186/s12916-018-1138-z.

The original article [1] contains errors in Table 1 affecting some of the presented oligonucleotide sequences and readthrough values in Table 1.

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Sermet-Gaudelus I, Renouil M, Fajac A, et al. Correction to: In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study. BMC Med. 2018;16(1):159doi: 10.1186/s12916-018-1138-z.
Sermet-Gaudelus, I., Renouil, M., Fajac, A., Bidou, L., Parbaille, B., Pierrot, S., Davy, N., Bismuth, E., Reinert, P., Lenoir, G., Lesure, J. F., Rousset, J. P., & Edelman, A. (2018). Correction to: In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study. BMC medicine, 16(1), 159. https://doi.org/10.1186/s12916-018-1138-z
Sermet-Gaudelus, I, et al. "Correction to: In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study." BMC medicine vol. 16,1 (2018): 159. doi: https://doi.org/10.1186/s12916-018-1138-z
Sermet-Gaudelus I, Renouil M, Fajac A, Bidou L, Parbaille B, Pierrot S, Davy N, Bismuth E, Reinert P, Lenoir G, Lesure JF, Rousset JP, Edelman A. Correction to: In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study. BMC Med. 2018 Aug 25;16(1):159. doi: 10.1186/s12916-018-1138-z. PMID: 30143037; PMCID: PMC6109304.
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Reversible electronic energy transfer: a means to govern excited-state properties of supramolecular systems.

Chemical Society reviews

Lavie-Cambot A, Lincheneau C, Cantuel M, Leydet Y, McClenaghan ND.
PMID: 20111775
Chem Soc Rev. 2010 Feb;39(2):506-15. doi: 10.1039/b810669j. Epub 2009 Sep 30.

A strategy to manage energy, following light absorption, and modulate excited-state properties, including luminescence lifetimes of multicomponent photoactive systems, is presented. The intervening mechanism, which is illustrated through the use of bi-/multi-chromophoric molecules, relies on energy shuttling between different...

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Lavie-Cambot A, Lincheneau C, Cantuel M, et al. Reversible electronic energy transfer: a means to govern excited-state properties of supramolecular systems. Chem Soc Rev. 2009;39(2):506-15doi: 10.1039/b810669j.
Lavie-Cambot, A., Lincheneau, C., Cantuel, M., Leydet, Y., & McClenaghan, N. D. (2010). Reversible electronic energy transfer: a means to govern excited-state properties of supramolecular systems. Chemical Society reviews, 39(2), 506-15. https://doi.org/10.1039/b810669j
Lavie-Cambot, Aurélie, et al. "Reversible electronic energy transfer: a means to govern excited-state properties of supramolecular systems." Chemical Society reviews vol. 39,2 (2010): 506-15. doi: https://doi.org/10.1039/b810669j
Lavie-Cambot A, Lincheneau C, Cantuel M, Leydet Y, McClenaghan ND. Reversible electronic energy transfer: a means to govern excited-state properties of supramolecular systems. Chem Soc Rev. 2010 Feb;39(2):506-15. doi: 10.1039/b810669j. Epub 2009 Sep 30. PMID: 20111775.
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GM3 synthase deficiency in non-Amish patients.

Genetics in medicine : official journal of the American College of Medical Genetics

Heide S, Jacquemont ML, Cheillan D, Renouil M, Tallot M, Schwartz CE, Miquel J, Bintner M, Rodriguez D, Darcel F, Buratti J, Haye D, Passemard S, Gras D, Perrin L, Capri Y, Gérard B, Piton A, Keren B, Thauvin-Robinet C, Duffourd Y, Faivre L, Poe C, Pervillé A, Héron D, Thévenon J, Arnaud L, LeGuern E, La Selva L, Vetro A, Guerrini R, Nava C, Mignot C.
PMID: 34906476
Genet Med. 2021 Nov 30; doi: 10.1016/j.gim.2021.10.007. Epub 2021 Nov 30.

PURPOSE: Biallelic loss-of-function variants in ST3GAL5 cause GM3 synthase deficiency (GM3SD) responsible for Amish infantile epilepsy syndrome. All Amish patients carry the homozygous p.(Arg288Ter) variant arising from a founder effect. To date only 10 patients from 4 non-Amish families...

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Heide S, Jacquemont ML, Cheillan D, et al. GM3 synthase deficiency in non-Amish patients. Genet Med. 2021;doi: 10.1016/j.gim.2021.10.007.
Heide, S., Jacquemont, M. L., Cheillan, D., Renouil, M., Tallot, M., Schwartz, C. E., Miquel, J., Bintner, M., Rodriguez, D., Darcel, F., Buratti, J., Haye, D., Passemard, S., Gras, D., Perrin, L., Capri, Y., Gérard, B., Piton, A., Keren, B., Thauvin-Robinet, C., Duffourd, Y., Faivre, L., Poe, C., Pervillé, A., Héron, D., Thévenon, J., Arnaud, L., LeGuern, E., La Selva, L., Vetro, A., Guerrini, R., Nava, C., & Mignot, C. (2021). GM3 synthase deficiency in non-Amish patients. Genetics in medicine : official journal of the American College of Medical Genetics, . https://doi.org/10.1016/j.gim.2021.10.007
Heide, Solveig, et al. "GM3 synthase deficiency in non-Amish patients." Genetics in medicine : official journal of the American College of Medical Genetics vol. (2021). doi: https://doi.org/10.1016/j.gim.2021.10.007
Heide S, Jacquemont ML, Cheillan D, Renouil M, Tallot M, Schwartz CE, Miquel J, Bintner M, Rodriguez D, Darcel F, Buratti J, Haye D, Passemard S, Gras D, Perrin L, Capri Y, Gérard B, Piton A, Keren B, Thauvin-Robinet C, Duffourd Y, Faivre L, Poe C, Pervillé A, Héron D, Thévenon J, Arnaud L, LeGuern E, La Selva L, Vetro A, Guerrini R, Nava C, Mignot C. GM3 synthase deficiency in non-Amish patients. Genet Med. 2021 Nov 30; doi: 10.1016/j.gim.2021.10.007. Epub 2021 Nov 30. PMID: 34906476.
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Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion.

Cell reports

Hu M, Cebola I, Carrat G, Jiang S, Nawaz S, Khamis A, Canouil M, Froguel P, Schulte A, Solimena M, Ibberson M, Marchetti P, Cardenas-Diaz FL, Gadue PJ, Hastoy B, Almeida-Souza L, McMahon H, Rutter GA.
PMID: 33730570
Cell Rep. 2021 Mar 16;34(11):108881. doi: 10.1016/j.celrep.2021.108881.

No abstract available.

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Hu M, Cebola I, Carrat G, et al. Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion. Cell Rep. 2021;34(11):108881doi: 10.1016/j.celrep.2021.108881.
Hu, M., Cebola, I., Carrat, G., Jiang, S., Nawaz, S., Khamis, A., Canouil, M., Froguel, P., Schulte, A., Solimena, M., Ibberson, M., Marchetti, P., Cardenas-Diaz, F. L., Gadue, P. J., Hastoy, B., Almeida-Souza, L., McMahon, H., & Rutter, G. A. (2021). Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion. Cell reports, 34(11), 108881. https://doi.org/10.1016/j.celrep.2021.108881
Hu, Ming, et al. "Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion." Cell reports vol. 34,11 (2021): 108881. doi: https://doi.org/10.1016/j.celrep.2021.108881
Hu M, Cebola I, Carrat G, Jiang S, Nawaz S, Khamis A, Canouil M, Froguel P, Schulte A, Solimena M, Ibberson M, Marchetti P, Cardenas-Diaz FL, Gadue PJ, Hastoy B, Almeida-Souza L, McMahon H, Rutter GA. Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion. Cell Rep. 2021 Mar 16;34(11):108881. doi: 10.1016/j.celrep.2021.108881. PMID: 33730570; PMCID: PMC7972990.
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Elevated circulating follistatin associates with an increased risk of type 2 diabetes.

Nature communications

Wu C, Borné Y, Gao R, López Rodriguez M, Roell WC, Wilson JM, Regmi A, Luan C, Aly DM, Peter A, Machann J, Staiger H, Fritsche A, Birkenfeld AL, Tao R, Wagner R, Canouil M, Hong MG, Schwenk JM, Ahlqvist E, Kaikkonen MU, Nilsson P, Shore AC, Khan F, Natali A, Melander O, Orho-Melander M, Nilsson J, Häring HU, Renström E, Wollheim CB, Engström G, Weng J, Pearson ER, Franks PW, White MF, Duffin KL, Vaag AA, Laakso M, Stefan N, Groop L, De Marinis Y.
PMID: 34759311
Nat Commun. 2021 Nov 10;12(1):6486. doi: 10.1038/s41467-021-26536-w.

The hepatokine follistatin is elevated in patients with type 2 diabetes (T2D) and promotes hyperglycemia in mice. Here we explore the relationship of plasma follistatin levels with incident T2D and mechanisms involved. Adjusted hazard ratio (HR) per standard deviation...

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Wu C, Borné Y, Gao R, et al. Elevated circulating follistatin associates with an increased risk of type 2 diabetes. Nat Commun. 2021;12(1):6486doi: 10.1038/s41467-021-26536-w.
Wu, C., Borné, Y., Gao, R., López Rodriguez, M., Roell, W. C., Wilson, J. M., Regmi, A., Luan, C., Aly, D. M., Peter, A., Machann, J., Staiger, H., Fritsche, A., Birkenfeld, A. L., Tao, R., Wagner, R., Canouil, M., Hong, M. G., Schwenk, J. M., Ahlqvist, E., Kaikkonen, M. U., Nilsson, P., Shore, A. C., Khan, F., Natali, A., Melander, O., Orho-Melander, M., Nilsson, J., Häring, H. U., Renström, E., Wollheim, C. B., Engström, G., Weng, J., Pearson, E. R., Franks, P. W., White, M. F., Duffin, K. L., Vaag, A. A., Laakso, M., Stefan, N., Groop, L., & De Marinis, Y. (2021). Elevated circulating follistatin associates with an increased risk of type 2 diabetes. Nature communications, 12(1), 6486. https://doi.org/10.1038/s41467-021-26536-w
Wu, Chuanyan, et al. "Elevated circulating follistatin associates with an increased risk of type 2 diabetes." Nature communications vol. 12,1 (2021): 6486. doi: https://doi.org/10.1038/s41467-021-26536-w
Wu C, Borné Y, Gao R, López Rodriguez M, Roell WC, Wilson JM, Regmi A, Luan C, Aly DM, Peter A, Machann J, Staiger H, Fritsche A, Birkenfeld AL, Tao R, Wagner R, Canouil M, Hong MG, Schwenk JM, Ahlqvist E, Kaikkonen MU, Nilsson P, Shore AC, Khan F, Natali A, Melander O, Orho-Melander M, Nilsson J, Häring HU, Renström E, Wollheim CB, Engström G, Weng J, Pearson ER, Franks PW, White MF, Duffin KL, Vaag AA, Laakso M, Stefan N, Groop L, De Marinis Y. Elevated circulating follistatin associates with an increased risk of type 2 diabetes. Nat Commun. 2021 Nov 10;12(1):6486. doi: 10.1038/s41467-021-26536-w. PMID: 34759311; PMCID: PMC8580990.
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