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[Explanation of the graduate course in medicine and surgery in the United States. Interview granted to "Minerva Medica" by Professor J. A. DiDio].

Minerva medica

Carafa M.
PMID: 5581848
Minerva Med. 1971 Apr;62(33):5-9.

No abstract available.

pH-responsive oleic acid based nanocarriers: Melanoma treatment strategies.

International journal of pharmaceutics

Rinaldi F, Forte J, Pontecorvi G, Hanieh PN, Carè A, Bellenghi M, Tirelli V, Ammendolia MG, Mattia G, Marianecci C, Puglisi R, Carafa M.
PMID: 34923052
Int J Pharm. 2021 Dec 16;613:121391. doi: 10.1016/j.ijpharm.2021.121391. Epub 2021 Dec 16.

Numerous clinical observations indicate that, despite novel therapeutic approaches, a high percentage of melanoma patients is non-responder or suffers of severe drug-related toxicity. To overcome these problems, we considered the option of designing, preparing and characterizing nanoemulsions and niosomes...

Nanoemulsions of .

Pharmaceutics

Rinaldi F, Maurizi L, Conte AL, Marazzato M, Maccelli A, Crestoni ME, Hanieh PN, Forte J, Conte MP, Zagaglia C, Longhi C, Marianecci C, Ammendolia MG, Carafa M.
PMID: 33494240
Pharmaceutics. 2021 Jan 21;13(2). doi: 10.3390/pharmaceutics13020134.

No abstract available.

pH-responsive oleic acid based nanocarriers: Melanoma treatment strategies.

International journal of pharmaceutics

Rinaldi F, Forte J, Pontecorvi G, Hanieh PN, Carè A, Bellenghi M, Tirelli V, Ammendolia MG, Mattia G, Marianecci C, Puglisi R, Carafa M.
PMID: 34923052
Int J Pharm. 2021 Dec 16;613:121391. doi: 10.1016/j.ijpharm.2021.121391. Epub 2021 Dec 16.

Numerous clinical observations indicate that, despite novel therapeutic approaches, a high percentage of melanoma patients is non-responder or suffers of severe drug-related toxicity. To overcome these problems, we considered the option of designing, preparing and characterizing nanoemulsions and niosomes...

Decoration of Nanovesicles with pH (Low) Insertion Peptide (pHLIP) for Targeted Delivery.

Nanoscale research letters

Rinaldi F, Hanieh PN, Del Favero E, Rondelli V, Brocca P, Pereira MC, Andreev OA, Reshetnyak YK, Marianecci C, Carafa M.
PMID: 30515583
Nanoscale Res Lett. 2018 Dec 04;13(1):391. doi: 10.1186/s11671-018-2807-8.

Acidity at surface of cancer cells is a hallmark of tumor microenvironments, which does not depend on tumor perfusion, thus it may serve as a general biomarker for targeting tumor cells. We used the pH (low) insertion peptide (pHLIP)...

CCTA in the diagnosis of coronary artery disease.

La Radiologia medica

Marano R, Rovere G, Savino G, Flammia FC, Carafa MRP, Steri L, Merlino B, Natale L.
PMID: 32964325
Radiol Med. 2020 Nov;125(11):1102-1113. doi: 10.1007/s11547-020-01283-y. Epub 2020 Sep 22.

The world of cardiac imaging is proposing to physicians an ever-increasing spectrum of options and tools with the disadvantages of patients presently submitted to multiple, sequential, time-consuming, and costly diagnostic procedures and tests, sometimes with contradicting results. In the...

Chitosan Glutamate-Coated Niosomes: A Proposal for Nose-to-Brain Delivery.

Pharmaceutics

Rinaldi F, Hanieh PN, Chan LKN, Angeloni L, Passeri D, Rossi M, Wang JT, Imbriano A, Carafa M, Marianecci C.
PMID: 29565809
Pharmaceutics. 2018 Mar 22;10(2). doi: 10.3390/pharmaceutics10020038.

The aim of this in vitro study is to prepare and characterize drug free and pentamidine loaded chitosan glutamate coated niosomes for intranasal drug delivery to reach the brain through intranasal delivery. Mucoadhesive properties and stability testing in various...

Hydrophilic Silver Nanoparticles Loaded into Niosomes: Physical-Chemical Characterization in View of Biological Applications.

Nanomaterials (Basel, Switzerland)

Rinaldi F, Del Favero E, Moeller J, Hanieh PN, Passeri D, Rossi M, Angeloni L, Venditti I, Marianecci C, Carafa M, Fratoddi I.
PMID: 31426465
Nanomaterials (Basel). 2019 Aug 17;9(8). doi: 10.3390/nano9081177.

Silver nanoparticles (AgNPs) are widely used as antibacterial agents and anticancer drugs, but often their low stability limits their mass production and broad applications. The use of niosomes as a carrier to protect and envelop AgNPs gives a new...

Long-Lasting, Antinociceptive Effects of pH-Sensitive Niosomes Loaded with Ibuprofen in Acute and Chronic Models of Pain.

Pharmaceutics

Marzoli F, Marianecci C, Rinaldi F, Passeri D, Rossi M, Minosi P, Carafa M, Pieretti S.
PMID: 30717144
Pharmaceutics. 2019 Feb 01;11(2). doi: 10.3390/pharmaceutics11020062.

Ibuprofen is one of the non-steroidal anti-inflammatory drugs (NSAIDs) widely used to treat pain conditions. NSAIDs encounter several obstacles to passing across biological membranes. To overcome these constraints, we decided to study the effects of a new pH-sensitive formulation...

pH-responsive Oleic Acid based nanocarriers: melanoma treatment strategies.

International journal of pharmaceutics

Rinaldi F, Forte J, Pontecorvi G, Nadia Hanieh P, Carè A, Bellenghi M, Tirelli V, Grazia Ammendolia M, Mattia G, Marianecci C, Puglisi R, Carafa M.
PMID: 34923052
Int J Pharm. 2021 Dec 16;121391. doi: 10.1016/j.ijpharm.2021.121391. Epub 2021 Dec 16.

Numerous clinical observations indicate that, despite novel therapeutic approaches, a high percentage of melanoma patients is non-responder or suffers of severe drug-related toxicity. To overcome these problems, we considered the option of designing, preparing and characterizing nanoemulsions and niosomes...

pH-responsive oleic acid based nanocarriers: Melanoma treatment strategies.

International journal of pharmaceutics

Rinaldi F, Forte J, Pontecorvi G, Hanieh PN, Carè A, Bellenghi M, Tirelli V, Ammendolia MG, Mattia G, Marianecci C, Puglisi R, Carafa M.
PMID: 34923052
Int J Pharm. 2021 Dec 16;613:121391. doi: 10.1016/j.ijpharm.2021.121391. Epub 2021 Dec 16.

Numerous clinical observations indicate that, despite novel therapeutic approaches, a high percentage of melanoma patients is non-responder or suffers of severe drug-related toxicity. To overcome these problems, we considered the option of designing, preparing and characterizing nanoemulsions and niosomes...

Surfactants, Nanomedicines and Nanocarriers: A Critical Evaluation on Clinical Trials.

Pharmaceutics

Dri DA, Marianecci C, Carafa M, Gaucci E, Gramaglia D.
PMID: 33805639
Pharmaceutics. 2021 Mar 13;13(3). doi: 10.3390/pharmaceutics13030381.

Advances, perspectives and innovation in drug delivery have increased in recent years; however, there is limited information available regarding the actual presence of surfactants, nanomedicines and nanocarriers in investigational medicinal products submitted as part of a request for authorization...

Showing 1 to 12 of 31 entries