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Showing 1 to 12 of 152 entries
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Unraveling Unprecedented Charge Carrier Mobility through Structure Property Relationship of Four Isomers of Didodecyl[1]benzothieno[3,2-b][1]benzothiophene.

Advanced materials (Deerfield Beach, Fla.)

Tsutsui Y, Schweicher G, Chattopadhyay B, Sakurai T, Arlin JB, Ruzié C, Aliev A, Ciesielski A, Colella S, Kennedy AR, Lemaur V, Olivier Y, Hadji R, Sanguinet L, Castet F, Osella S, Dudenko D, Beljonne D, Cornil J, Samorì P, Seki S, Geerts YH.
PMID: 27226066
Adv Mater. 2016 Sep;28(33):7106-14. doi: 10.1002/adma.201601285. Epub 2016 May 25.

The structural and electronic properties of four isomers of didodecyl[1]-benzothieno[3,2-b][1]benzothiophene (C12-BTBT) have been investigated. Results show the strong impact of the molecular packing on charge carrier transport and electronic polarization properties. Field-induced time-resolved microwave conductivity measurements unravel an unprecedented...

Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatment.

Molecular & cellular oncology

Castel P, Toska E, Zumsteg ZS, Carmona FJ, Elkabets M, Bosch A, Scaltriti M.
PMID: 27308344
Mol Cell Oncol. 2014 Oct 29;1(3):e963447. doi: 10.4161/23723548.2014.963447. eCollection 2014.

The PI3K/AKT/mTOR signaling is important for cell proliferation, survival, and metabolism. Hyperactivation of this pathway is one of the most common signaling abnormalities observed in cancer and a substantial effort has recently been made to develop molecules targeting this...

Combination of Cyanine Behaviour and Giant Hyperpolarisability in Novel Merocyanine Dyes: Beyond the Bond Length Alternation (BLA) Paradigm.

Chemistry (Weinheim an der Bergstrasse, Germany)

Parthasarathy V, Pandey R, Stolte M, Ghosh S, Castet F, Würthner F, Das PK, Blanchard-Desce M.
PMID: 26249759
Chemistry. 2015 Sep 28;21(40):14211-7. doi: 10.1002/chem.201501800. Epub 2015 Aug 06.

Merocyanine dyes that exhibit antithetic cyanine-like behaviour and giant first-order hyperpolarisability (β) values have been designed. These cyanine-type dyes open up an intriguing route towards molecular-based electro-optic materials as well as new second-harmonic generation dyes for imaging.

A multistate pH-triggered nonlinear optical switch.

Chemphyschem : a European journal of chemical physics and physical chemistry

Castet F, Champagne B, Pina F, Rodriguez V.
PMID: 24863552
Chemphyschem. 2014 Aug 04;15(11):2221-4. doi: 10.1002/cphc.201402190. Epub 2014 May 23.

By using hyper-Rayleigh scattering experiments and quantum-chemical calculations, we demonstrate that nonlinear optics can be used to probe unequivocally, within a non-destructive process, the multiple electronic states that are activated upon pH- and light-triggered transformations of the 4'-hydroxyflavylium ion....

Theoretical investigation of the second-order nonlinear optical properties of helical pyridine-pyrimidine oligomers.

Chemistry (Weinheim an der Bergstrasse, Germany)

Botek E, Castet F, Champagne B.
PMID: 17048283
Chemistry. 2006 Nov 24;12(34):8687-95. doi: 10.1002/chem.200600551.

The structure and second-order nonlinear optical properties of a series of helical pyridine-pyrimidine oligomers recently synthesized by Barboiu and Lehn have been investigated theoretically by combining molecular mechanics and quantum chemistry approaches. In the absence of substituents, the hyper-Rayleigh...

Acidoswitchable NLO-phores: benzimidazolo[2,3-b]oxazolidines.

The journal of physical chemistry. B

Sanguinet L, Pozzo JL, Guillaume M, Champagne B, Castet F, Ducasse L, Maury E, Soulié J, Mançois F, Adamietz F, Rodriguez V.
PMID: 16771313
J Phys Chem B. 2006 Jun 08;110(22):10672-82. doi: 10.1021/jp060825g.

This paper presents a series of acidoswitchable NLO-phores combining the 9-methylbenzimidazolo[2,3-b]oxazolidine core with various pi systems such as phenylethenyl, phenylethynyl, and naphthylethenyl. All the prepared derivatives are shown to display acidochromic behavior at ambient temperature. The remarkable contrast in...

Theoretical investigation of the linear and second-order nonlinear susceptibilities of the 3-methyl-4-nitropyridine-1-oxyde (POM) crystal.

The Journal of chemical physics

Guillaume M, Botek E, Champagne B, Castet F, Ducasse L.
PMID: 15473810
J Chem Phys. 2004 Oct 15;121(15):7390-400. doi: 10.1063/1.1790952.

The linear and nonlinear optical properties of the 3-methyl-4-nitropyridine-1-oxyde (POM) crystal have been evaluated using semiempirical quantum chemistry techniques. The scheme includes (i) the evaluation of the polarizability and first hyperpolarizability of increasingly large one-dimensional, two-dimensional, and three-dimensional clusters...

Two-way molecular switches with large nonlinear optical contrast.

Chemistry (Weinheim an der Bergstrasse, Germany)

Mançois F, Pozzo JL, Pan J, Adamietz F, Rodriguez V, Ducasse L, Castet F, Plaquet A, Champagne B.
PMID: 19180595
Chemistry. 2009 Mar 02;15(11):2560-71. doi: 10.1002/chem.200801967.

Molecular switches: Highly efficient acido- and photoswitchable frequency doublers (see scheme) based on the indolinooxazolidine core are studied by means of hyper-Rayleigh experiments and quantum-chemical calculations.To optimize the nonlinear optical (NLO) contrast, a series of indolinooxazolidine derivatives with electron-withdrawing...

Plasma PCSK9 concentrations during an oral fat load and after short term high-fat, high-fat high-protein and high-fructose diets.

Nutrition & metabolism

Cariou B, Langhi C, Le Bras M, Bortolotti M, Lê KA, Theytaz F, Le May C, Guyomarc'h-Delasalle B, Zaïr Y, Kreis R, Boesch C, Krempf M, Tappy L, Costet P.
PMID: 23298392
Nutr Metab (Lond). 2013 Jan 08;10(1):4. doi: 10.1186/1743-7075-10-4.

BACKGROUND: PCSK9 (Proprotein Convertase Subtilisin Kexin type 9) is a circulating protein that promotes hypercholesterolemia by decreasing hepatic LDL receptor protein. Under non interventional conditions, its expression is driven by sterol response element binding protein 2 (SREBP2) and follows...

Charge dissociation at interfaces between discotic liquid crystals: the surprising role of column mismatch.

Journal of the American Chemical Society

Idé J, Méreau R, Ducasse L, Castet F, Bock H, Olivier Y, Cornil J, Beljonne D, D'Avino G, Roscioni OM, Muccioli L, Zannoni C.
PMID: 24456296
J Am Chem Soc. 2014 Feb 19;136(7):2911-20. doi: 10.1021/ja4114769. Epub 2014 Feb 10.

The semiconducting and self-assembling properties of columnar discotic liquid crystals have stimulated intense research toward their application in organic solar cells, although with a rather disappointing outcome to date in terms of efficiencies. These failures call for a rational...

Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy.

Skeletal muscle

Bentzinger CF, Lin S, Romanino K, Castets P, Guridi M, Summermatter S, Handschin C, Tintignac LA, Hall MN, Rüegg MA.
PMID: 23497627
Skelet Muscle. 2013 Mar 06;3(1):6. doi: 10.1186/2044-5040-3-6.

BACKGROUND: Skeletal muscle mass is determined by the balance between protein synthesis and degradation. Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of protein translation and has been implicated in the control of muscle mass. Inactivation...

Characterization of the role of phosphogypsum foam in the transport of metals and radionuclides in the Southern Mediterranean Sea.

Journal of hazardous materials

El Zrelli R, Rabaoui L, Abda H, Daghbouj N, Pérez-López R, Castet S, Aigouy T, Bejaoui N, Courjault-Radé P.
PMID: 30308365
J Hazard Mater. 2019 Feb 05;363:258-267. doi: 10.1016/j.jhazmat.2018.09.083. Epub 2018 Oct 02.

The Gabes Gulf had received huge quantities of phosphogypsum discharged from fertilizer plants. Dumping phosphogypsum in coastal waters leads to the formation of foam layers which can float on the surface and be passively transported to distant areas. This...

Showing 1 to 12 of 152 entries