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Showing 1 to 12 of 24 entries
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Densely PEGylated Polybenzofulvene Brushes for Potential Applications in Drug Encapsulation.

Pharmaceutics

Paolino M, Grisci G, Castriconi F, Reale A, Giuliani G, Donati A, Bonechi C, Giorgi G, Mendichi R, Piovani D, Boccia AC, Canetti M, Samperi F, Dattilo S, Scialabba C, Licciardi M, Paccagnini E, Gentile M, Cappelli A.
PMID: 30445768
Pharmaceutics. 2018 Nov 15;10(4). doi: 10.3390/pharmaceutics10040234.

The technique of grafting side chains onto a linear polymeric backbone is commonly used to confer to the new polymeric material with desired properties, such as tunable solubility, ionic charge, biocompatibility, or specific interactions with biological systems. In this...

Multivalent ligands for the serotonin 5-HT.

MedChemComm

Castriconi F, Paolino M, Donati A, Giuliani G, Anzini M, Mennuni L, Sabatini C, Lanza M, Caselli G, Makovec F, Sbraccia M, Molinari P, Costa T, Cappelli A.
PMID: 30108781
Medchemcomm. 2017 Feb 09;8(3):647-651. doi: 10.1039/c6md00458j. eCollection 2017 Mar 01.

5-HT

Non-Operative Management of Blunt Liver Trauma: Safety, Efficacy and Complications of a Standardized Treatment Protocol.

Bulletin of emergency and trauma

Brillantino A, Iacobellis F, Festa P, Mottola A, Acampora C, Corvino F, Del Giudice S, Lanza M, Armellino M, Niola R, Romano L, Castriconi M, De Palma M, Noschese G.
PMID: 30719466
Bull Emerg Trauma. 2019 Jan;7(1):49-54. doi: 10.29252/beat-070107.

OBJECTIVE: To evaluate the safety and effectiveness of NOM (non-operative management) in the treatment of blunt liver trauma, following a standardized treatment protocol.METHODS: All the hemodynamically stable patients with computed tomography (CT) diagnosis of blunt liver trauma underwent NOM....

Replacing Manual Planning of Whole Breast Irradiation With Knowledge-Based Automatic Optimization by Virtual Tangential-Fields Arc Therapy.

Frontiers in oncology

Castriconi R, Esposito PG, Tudda A, Mangili P, Broggi S, Fodor A, Deantoni CL, Longobardi B, Pasetti M, Perna L, Del Vecchio A, Di Muzio NG, Fiorino C.
PMID: 34504790
Front Oncol. 2021 Aug 24;11:712423. doi: 10.3389/fonc.2021.712423. eCollection 2021.

PURPOSE: To implement Knowledge Based (KB) automatic planning for right and left-sided whole breast treatment through a new volumetric technique (ViTAT, Virtual Tangential-fields Arc Therapy) mimicking conventional tangential fields (TF) irradiation.MATERIALS AND METHOD: A total of 193 clinical plans...

Local Autologous Stem Cells Application in Rotator Cuff Repairs: "LASCA" Technique.

Arthroscopy techniques

Dei Giudici L, Castricini R.
PMID: 33134062
Arthrosc Tech. 2020 Oct 16;9(10):e1571-e1575. doi: 10.1016/j.eats.2020.06.022. eCollection 2020 Oct.

Rotator cuff tears are among the most common orthopaedic conditions, with a very high social impact. A major concern is failure rates. To reduce these rates, recent years have seen increased attention to the biological augmentation of rotator cuff...

Usefulness of damage control approach in patients with limited acute mesenteric ischemia: a prospective study of 85 patients.

Updates in surgery

Brillantino A, Lanza M, Antropoli M, Amendola A, Squillante S, Bottino V, Renzi A, Castriconi M.
PMID: 34686970
Updates Surg. 2021 Oct 22; doi: 10.1007/s13304-021-01192-3. Epub 2021 Oct 22.

To evaluate the efficacy of the damage control approach by two-step surgical procedure in not critical patients (without sepsis or septic shock) with peritonitis from limited acute mesenteric ischemia. From April 2013 to April 2020, 85 patients [49 (57.7%)...

Implementation of automatic plan optimization in Italy: Status and perspectives.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

Pallotta S, Marrazzo L, Calusi S, Castriconi R, Fiorino C, Loi G, Fiandra C.
PMID: 34875426
Phys Med. 2021 Dec 04;92:86-94. doi: 10.1016/j.ejmp.2021.11.013. Epub 2021 Dec 04.

PURPOSE: To investigate and report on the diffusion and clinical use of automated radiotherapy planning systems in Italy and to assess the perspectives of the community of Italian medical physicists involved in radiotherapy on the use of these tools.MATERIALS...

Multiparametric flow cytometry highlights B7-H3 as a novel diagnostic/therapeutic target in GD2neg/low neuroblastoma variants.

Journal for immunotherapy of cancer

Dondero A, Morini M, Cangelosi D, Mazzocco K, Serra M, Spaggiari GM, Rotta G, Tondo A, Locatelli F, Castellano A, Scuderi F, Sementa AR, Eva A, Conte M, Garaventa A, Bottino C, Castriconi R.
PMID: 33795387
J Immunother Cancer. 2021 Apr;9(4). doi: 10.1136/jitc-2020-002293.

BACKGROUND: High-risk neuroblastomas (HR-NBs) are rare, aggressive pediatric cancers characterized by resistance to therapy and relapse in more than 30% of cases, despite using an aggressive therapeutic protocol including targeting of GD2. The mechanisms responsible for therapy resistance are...

Arthroscopic Latarjet Procedure: A Technique Using Double Round ENDOBUTTONs and Specific Glenoid and Coracoid Guides.

Arthroscopy techniques

Castricini R, Taverna E, Guarrella V, De Benedetto M, Galasso O.
PMID: 32714810
Arthrosc Tech. 2020 Jun 25;9(7):e995-e1001. doi: 10.1016/j.eats.2020.03.019. eCollection 2020 Jul.

The Latarjet procedure is a method used for the treatment of shoulder instability in the presence of bone loss. A decade after the first description of the fully arthroscopic Latarjet procedure, modifications to the technique were reported to decrease...

TGF-β1 Downregulates the Expression of CX.

Frontiers in immunology

Regis S, Caliendo F, Dondero A, Casu B, Romano F, Loiacono F, Moretta A, Bottino C, Castriconi R.
PMID: 28791023
Front Immunol. 2017 Jul 25;8:868. doi: 10.3389/fimmu.2017.00868. eCollection 2017.

Activity of human natural killer (NK) cells against cancer cells is deeply suppressed by TGF-β1, an immunomodulatory cytokine that is released and activated in the tumor microenvironment. Moreover, our previous data showed that TGF-β1 modifies the chemokine receptor repertoire...

Toxicity of Hypofractionated Whole Breast Radiotherapy Without Boost and Timescale of Late Skin Responses in a Large Cohort of Early-Stage Breast Cancer Patients.

Clinical breast cancer

Fodor A, Brombin C, Mangili P, Tummineri R, Pasetti M, Zerbetto F, Longobardi B, Galvan AS, Deantoni CL, Dell'Oca I, Castriconi R, Esposito PG, Deli AM, Rancoita PMV, Fiorino C, Vecchio AD, Di Serio MS, Di Muzio NG.
PMID: 34955430
Clin Breast Cancer. 2021 Dec 01; doi: 10.1016/j.clbc.2021.11.008. Epub 2021 Dec 01.

AIM: To report toxicity of hypofractionated whole-breast radiotherapy in a large cohort of early-stage breast cancer (BCaients.MATERIALS AND METHODS: From 02/2009-05/2017, 1325 consecutive BCa patients were treated with 40.05 Gy/15 fractions, without boost. Median age was 62 (IQR:51.1-70.5) years....

Novel Immunoregulatory Functions of IL-18, an Accomplice of TGF-β1.

Cancers

Casu B, Dondero A, Regis S, Caliendo F, Petretto A, Bartolucci M, Bellora F, Bottino C, Castriconi R.
PMID: 30641867
Cancers (Basel). 2019 Jan 11;11(1). doi: 10.3390/cancers11010075.

TGF-β1 is a pleiotropic factor exerting a strong regulatory role in several cell types, including immune cells. In NK cells it profoundly alters the surface expression of crucial activating and chemokine receptors. To understand which soluble signals might better...

Showing 1 to 12 of 24 entries