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Showing 1 to 10 of 10 entries
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5'RUNX1-3'USP42 chimeric gene in acute myeloid leukemia can occur through an insertion mechanism rather than translocation and may be mediated by genomic segmental duplications.

Molecular cytogenetics

Zagaria A, Anelli L, Coccaro N, Tota G, Casieri P, Cellamare A, Minervini A, Minervini CF, Brunetti C, Cumbo C, Specchia G, Albano F.
PMID: 25298786
Mol Cytogenet. 2014 Oct 01;7(1):66. doi: 10.1186/s13039-014-0066-7. eCollection 2014.

BACKGROUND: The runt-related transcription factor 1 (RUNX1) gene is a transcription factor that acts as a master regulator of hematopoiesis and represents one of the most frequent targets of chromosomal rearrangements in human leukemias. The t(7;21)(p22;q22) rearrangement generating a...

Synthesis and Biological Evaluation of Dantrolene-Like Hydrazide and Hydrazone Analogues as Multitarget Agents for Neurodegenerative Diseases.

ChemMedChem

Bolognino I, Giangregorio N, Tonazzi A, Martínez AL, Altomare CD, Loza MI, Sablone S, Cellamare S, Catto M.
PMID: 34047061
ChemMedChem. 2021 Sep 16;16(18):2807-2816. doi: 10.1002/cmdc.202100209. Epub 2021 Jun 22.

Dantrolene, a drug used for the management of malignant hyperthermia, had been recently evaluated for prospective repurposing as multitarget agent for neurodegenerative syndromes, including Alzheimer's disease (AD). Herein, twenty-one dantrolene-like hydrazide and hydrazone analogues were synthesized with the aim...

Regiodivergent synthesis of functionalized pyrimidines and imidazoles through phenacyl azides in deep eutectic solvents.

Beilstein journal of organic chemistry

Vitale P, Cicco L, Cellamare I, Perna FM, Salomone A, Capriati V.
PMID: 32802208
Beilstein J Org Chem. 2020 Aug 05;16:1915-1923. doi: 10.3762/bjoc.16.158. eCollection 2020.

We report that phenacyl azides are key compounds for a regiodivergent synthesis of valuable, functionalized imidazole (32-98% yield) and pyrimidine derivatives (45-88% yield), with a broad substrate scope, when using deep eutectic solvents [choline chloride (ChCl)/glycerol (1:2 mol/mol) and...

Cytogenetic and Array-CGH Characterization of a Simple Case of Reciprocal t(3;10) Translocation Reveals a Hidden Deletion at 5q12.

Genes

Cellamare A, Coccaro N, Nuzzi MC, Casieri P, Tampoia M, Maggiolini FAM, Gentile M, Ficarella R, Ponzi E, Conserva MR, Cardarelli L, Panarese A, Antonacci F, Gesario A.
PMID: 34200357
Genes (Basel). 2021 Jun 07;12(6). doi: 10.3390/genes12060877.

Chromosome deletions, including band 5q12, have rarely been reported and have been associated with a wide range of clinical manifestations, such as postnatal growth retardation, intellectual disability, hyperactivity, nonspecific ocular defects, facial dysmorphism, and epilepsy. In this study, we...

Oncology letters

Coccaro N, Tota G, Anelli L, Zagaria A, Casieri P, Cellamare A, Minervini CF, Minervini A, Cumbo C, Impera L, Brunetti C, Orsini P, Parciante E, Mestice A, Specchia G, Albano F.
PMID: 27446453
Oncol Lett. 2016 Aug;12(2):1460-1464. doi: 10.3892/ol.2016.4759. Epub 2016 Jun 22.

Primary plasma cell leukemia (pPCL) is an uncommon form of plasma cell dyscrasia, and the most aggressive of the human monoclonal gammopathies. The t(11;14)(q13;q32) rearrangement is the most common alteration in pPCL, promoting

Left ventricular reverse remodeling after transcatheter aortic valve implantation complicated by paroxysmal complete atrioventricular block.

Journal of cardiology cases

Segreti L, Ujka K, Cellamaro T, Zucchelli G, Di Cori A, Soldati E, Bongiorni MG.
PMID: 30279890
J Cardiol Cases. 2018 Mar 08;17(6):194-196. doi: 10.1016/j.jccase.2018.01.010. eCollection 2018 Jun.

An 86-year-old man with unremarkable clinical history complaining of asthenia and dyspnea was diagnosed with low-flow low-gradient aortic stenosis [LFLG-AS; left ventricular ejection fraction (LVEF) 40% and transaortic mean gradient 37 mmHg, increasing to 52% and 55 mmHg after...

Lower Extremity Kinematics of the Y-Balance Test in Healthy and ACL Injured Adolescent Females.

International journal of sports physical therapy

Bulow A, Bellemare A, Anderson JE, Leiter JRS, MacDonald PB, Peeler JD.
PMID: 33842034
Int J Sports Phys Ther. 2021 Apr 01;16(2):381-392. doi: 10.26603/001c.21529.

BACKGROUND: Adolescent females are at significant risk for sustaining an ACL injury. The Y-Balance Test (YBT) is frequently used to evaluate neuromuscular control and lower extremity function. However, few studies have quantified 2D lower extremity kinematics during performance of...

Comparison of Common Methodologies for the Determination of Knee Flexor Muscle Strength.

International journal of sports physical therapy

Ogborn DI, Bellemare A, Bruinooge B, Brown H, McRae S, Leiter J.
PMID: 33842031
Int J Sports Phys Ther. 2021 Apr 01;16(2):350-359. doi: 10.26603/001c.21311.

BACKGROUND: Knee flexion strength may hold important clinical implications for the determination of injury risk and readiness to return to sport following injury and orthopedic surgery. A wide array of testing methodologies and positioning options are available that require...

Correction to: The Italian validation of the communicative effectiveness index questionnaire: a multicentric study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Moretta P, Lanzillo A, Lo Sapio MD, Spaccavento S, Cellamare F, Nisoli F, Ianni A, Pain D, Feroldi S, Forlani CA, Boccola S, Madonia F, Volanti P, Pierobon A, Scola I, Manera M, Bertolotti G, Trojano L.
PMID: 33856583
Neurol Sci. 2021 Jun;42(6):2601. doi: 10.1007/s10072-021-05256-5.

No abstract available.

Effects of computer-based therapy versus therapist-mediated therapy in stroke-related aphasia: Pilot non-inferiority study.

Journal of communication disorders

Spaccavento S, Falcone R, Cellamare F, Picciola E, Glueckauf RL.
PMID: 34673449
J Commun Disord. 2021 Nov-Dec;94:106158. doi: 10.1016/j.jcomdis.2021.106158. Epub 2021 Oct 08.

PURPOSE: The burgeoning growth of computer-based rehabilitation technologies has led to a paradigm shift in the delivery of aphasia intervention. The aim of this study was to conduct a pilot non-inferiority study comparing computer-based training for people with aphasia...

Showing 1 to 10 of 10 entries