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Unmet needs in the diagnosis and treatment of mood disorders in later life

classroom interventions

Charney DS.
GSID: qHKWqf1D2EkJ
CF Reynolds, DS Charney - Biological Psychiatry, 2002 - biologicalpsychiatryjournal.com

Mood disorders in later life are now recognized as a major public health problem. Depression is prevalent, persistent, disabling, and sometimes fatal, entailing the highest …

Commonly Measured Clinical Variables Are Not Associated With Burden of Complications in Long-standing Type 1 Diabetes: Results From the Canadian Study of Longevity in Diabetes.

Diabetes care

Weisman A, Rovinski R, Farooqi MA, Lovblom LE, Halpern EM, Boulet G, Eldelekli D, Keenan HA, Brent MH, Paul N, Bril V, Cherney DZ, Perkins BA.
PMID: 27006509
Diabetes Care. 2016 May;39(5):e67-8. doi: 10.2337/dc16-0102. Epub 2016 Mar 22.

No abstract available.

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Weisman A, Rovinski R, Farooqi MA, et al. Commonly Measured Clinical Variables Are Not Associated With Burden of Complications in Long-standing Type 1 Diabetes: Results From the Canadian Study of Longevity in Diabetes. Diabetes Care. 2016;39(5):e67-8doi: 10.2337/dc16-0102.
Weisman, A., Rovinski, R., Farooqi, M. A., Lovblom, L. E., Halpern, E. M., Boulet, G., Eldelekli, D., Keenan, H. A., Brent, M. H., Paul, N., Bril, V., Cherney, D. Z., & Perkins, B. A. (2016). Commonly Measured Clinical Variables Are Not Associated With Burden of Complications in Long-standing Type 1 Diabetes: Results From the Canadian Study of Longevity in Diabetes. Diabetes care, 39(5), e67-8. https://doi.org/10.2337/dc16-0102
Weisman, Alanna, et al. "Commonly Measured Clinical Variables Are Not Associated With Burden of Complications in Long-standing Type 1 Diabetes: Results From the Canadian Study of Longevity in Diabetes." Diabetes care vol. 39,5 (2016): e67-8. doi: https://doi.org/10.2337/dc16-0102
Weisman A, Rovinski R, Farooqi MA, Lovblom LE, Halpern EM, Boulet G, Eldelekli D, Keenan HA, Brent MH, Paul N, Bril V, Cherney DZ, Perkins BA. Commonly Measured Clinical Variables Are Not Associated With Burden of Complications in Long-standing Type 1 Diabetes: Results From the Canadian Study of Longevity in Diabetes. Diabetes Care. 2016 May;39(5):e67-8. doi: 10.2337/dc16-0102. Epub 2016 Mar 22. PMID: 27006509.
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Treating Swallowing Disorders following Stroke.

Topics in stroke rehabilitation

Martin-Harris B, Cherney LR.
PMID: 27681826
Top Stroke Rehabil. 1996 Sep;3(3):27-40. doi: 10.1080/10749357.1996.11754120.

The speech-language pathologist uses a combination of direct and indirect treatment techniques to manage dysphagia in the patient with a stroke. This article reviews a variety of these procedures, including patient and family education, sensory stimulation techniques such as...

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Martin-Harris B, Cherney LR. Treating Swallowing Disorders following Stroke. Top Stroke Rehabil. 1996;3(3):27-40doi: 10.1080/10749357.1996.11754120.
Martin-Harris, B., & Cherney, L. R. (1996). Treating Swallowing Disorders following Stroke. Topics in stroke rehabilitation, 3(3), 27-40. https://doi.org/10.1080/10749357.1996.11754120
Martin-Harris, Bonnie, and Cherney, Leora Reiff. "Treating Swallowing Disorders following Stroke." Topics in stroke rehabilitation vol. 3,3 (1996): 27-40. doi: https://doi.org/10.1080/10749357.1996.11754120
Martin-Harris B, Cherney LR. Treating Swallowing Disorders following Stroke. Top Stroke Rehabil. 1996 Sep;3(3):27-40. doi: 10.1080/10749357.1996.11754120. PMID: 27681826.
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Resilience: The role of accurate appraisal, thresholds, and socioenvironmental factors.

The Behavioral and brain sciences

Southwick SM, Pietrzak RH, Charney DS, Krystal JH.
PMID: 26786005
Behav Brain Sci. 2015;38:e122. doi: 10.1017/S0140525X14001708.

Adding to the resilience model of Kalisch and colleagues, we suggest that resilience is associated with accurate rather than excessively positive or negative appraisal or reappraisal styles; that complex systems do not always change in linear fashion; that linkages...

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Southwick SM, Pietrzak RH, Charney DS, et al. Resilience: The role of accurate appraisal, thresholds, and socioenvironmental factors. Behav Brain Sci. 2015;38:e122doi: 10.1017/S0140525X14001708.
Southwick, S. M., Pietrzak, R. H., Charney, D. S., & Krystal, J. H. (2015). Resilience: The role of accurate appraisal, thresholds, and socioenvironmental factors. The Behavioral and brain sciences, 38e122. https://doi.org/10.1017/S0140525X14001708
Southwick, Steven M, et al. "Resilience: The role of accurate appraisal, thresholds, and socioenvironmental factors." The Behavioral and brain sciences vol. 38 (2015): e122. doi: https://doi.org/10.1017/S0140525X14001708
Southwick SM, Pietrzak RH, Charney DS, Krystal JH. Resilience: The role of accurate appraisal, thresholds, and socioenvironmental factors. Behav Brain Sci. 2015;38:e122. doi: 10.1017/S0140525X14001708. PMID: 26786005.
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Two approaches to treating unilateral neglect after right hemisphere stroke: a preliminary investigation.

Topics in stroke rehabilitation

Cherney LR, Halper AS, Papachronis D.
PMID: 14523697
Top Stroke Rehabil. 2003;9(4):22-33. doi: 10.1310/BWY3-7GQL-596Y-V17J.

PURPOSE: This preliminary study assessed the efficacy of two treatment methods for persistent unilateral or hemispatial neglect following right hemisphere stroke.METHOD: Two patients received an intervention focusing on the underlying impairment of attention during visual scanning. Two other participants...

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Cherney LR, Halper AS, Papachronis D. Two approaches to treating unilateral neglect after right hemisphere stroke: a preliminary investigation. Top Stroke Rehabil. 2003;9(4):22-33doi: 10.1310/BWY3-7GQL-596Y-V17J.
Cherney, L. R., Halper, A. S., & Papachronis, D. (2003). Two approaches to treating unilateral neglect after right hemisphere stroke: a preliminary investigation. Topics in stroke rehabilitation, 9(4), 22-33. https://doi.org/10.1310/BWY3-7GQL-596Y-V17J
Cherney, Leora R, et al. "Two approaches to treating unilateral neglect after right hemisphere stroke: a preliminary investigation." Topics in stroke rehabilitation vol. 9,4 (2003): 22-33. doi: https://doi.org/10.1310/BWY3-7GQL-596Y-V17J
Cherney LR, Halper AS, Papachronis D. Two approaches to treating unilateral neglect after right hemisphere stroke: a preliminary investigation. Top Stroke Rehabil. 2003;9(4):22-33. doi: 10.1310/BWY3-7GQL-596Y-V17J. PMID: 14523697.
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Comparison of discrete and continuous motion in scanning probe microscopy monitored via confocal Raman microspectroscopy.

Applied spectroscopy

Cherney DP, Winesett DA.
PMID: 18559148
Appl Spectrosc. 2008 Jun;62(6):617-23. doi: 10.1366/000370208784657959.

Confocal Raman imaging is a relatively new analytical technique that combines the strengths of Raman microspectroscopy and confocal optics. The images collected by the microscope are obtained by monitoring specific bands in the Raman spectra that are collected at...

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Cherney DP, Winesett DA. Comparison of discrete and continuous motion in scanning probe microscopy monitored via confocal Raman microspectroscopy. Appl Spectrosc. 2008;62(6):617-23doi: 10.1366/000370208784657959.
Cherney, D. P., & Winesett, D. A. (2008). Comparison of discrete and continuous motion in scanning probe microscopy monitored via confocal Raman microspectroscopy. Applied spectroscopy, 62(6), 617-23. https://doi.org/10.1366/000370208784657959
Cherney, Daniel P, and Winesett, Donald A. "Comparison of discrete and continuous motion in scanning probe microscopy monitored via confocal Raman microspectroscopy." Applied spectroscopy vol. 62,6 (2008): 617-23. doi: https://doi.org/10.1366/000370208784657959
Cherney DP, Winesett DA. Comparison of discrete and continuous motion in scanning probe microscopy monitored via confocal Raman microspectroscopy. Appl Spectrosc. 2008 Jun;62(6):617-23. doi: 10.1366/000370208784657959. PMID: 18559148.
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Cellular plasticity and resilience and the pathophysiology of severe mood disorders.

Dialogues in clinical neuroscience

Charney DS, Dejesus G, Manji HK.
PMID: 22033657
Dialogues Clin Neurosci. 2004 Jun;6(2):217-25.

Recent advances in the identification of the neural circuits, neurochemicals, and signal transduction mechanisms involved in the pathophysiology and treatment of mood disorders have led to much progress toward understanding the roles of genetic factors and psychosocial stressors. The...

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Charney DS, Dejesus G, Manji HK. Cellular plasticity and resilience and the pathophysiology of severe mood disorders. Dialogues Clin Neurosci. 2004;6(2):217-25
Charney, D. S., Dejesus, G., & Manji, H. K. (2004). Cellular plasticity and resilience and the pathophysiology of severe mood disorders. Dialogues in clinical neuroscience, 6(2), 217-25.
Charney, Dennis S, et al. "Cellular plasticity and resilience and the pathophysiology of severe mood disorders." Dialogues in clinical neuroscience vol. 6,2 (2004): 217-25.
Charney DS, Dejesus G, Manji HK. Cellular plasticity and resilience and the pathophysiology of severe mood disorders. Dialogues Clin Neurosci. 2004 Jun;6(2):217-25. PMID: 22033657; PMCID: PMC3181794.
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Epidural cortical stimulation and aphasia therapy.

Aphasiology

Cherney LR, Harvey RL, Babbitt EM, Hurwitz R, Kaye RC, Lee JB, Small SL.
PMID: 23667287
Aphasiology. 2012 Sep 01;26(9):1192-1217. doi: 10.1080/02687038.2011.603719.

BACKGROUND: There are several methods of delivering cortical brain stimulation to modulate cortical excitability and interest in their application as an adjuvant strategy in aphasia rehabilitation after stroke is growing. Epidural cortical stimulation, although more invasive than other methods,...

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Cherney LR, Harvey RL, Babbitt EM, et al. Epidural cortical stimulation and aphasia therapy. Aphasiology. 2012;26(9):1192-1217doi: 10.1080/02687038.2011.603719.
Cherney, L. R., Harvey, R. L., Babbitt, E. M., Hurwitz, R., Kaye, R. C., Lee, J. B., & Small, S. L. (2012). Epidural cortical stimulation and aphasia therapy. Aphasiology, 26(9), 1192-1217. https://doi.org/10.1080/02687038.2011.603719
Cherney, Leora R, et al. "Epidural cortical stimulation and aphasia therapy." Aphasiology vol. 26,9 (2012): 1192-1217. doi: https://doi.org/10.1080/02687038.2011.603719
Cherney LR, Harvey RL, Babbitt EM, Hurwitz R, Kaye RC, Lee JB, Small SL. Epidural cortical stimulation and aphasia therapy. Aphasiology. 2012 Sep 01;26(9):1192-1217. doi: 10.1080/02687038.2011.603719. PMID: 23667287; PMCID: PMC3647471.
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The psychobiology of resilience and vulnerability to anxiety disorders: implications for prevention and treatment.

Dialogues in clinical neuroscience

Charney DS.
PMID: 22034473
Dialogues Clin Neurosci. 2003 Sep;5(3):207-21.

Much of the research on the neurobiology of human anxiety disorders has focused on psychopaihological abnormalities in patients with anxiety disorders. While this line of research is obviously important, more investigation is needed to elucidate the psychobiology of resilience...

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Charney DS. The psychobiology of resilience and vulnerability to anxiety disorders: implications for prevention and treatment. Dialogues Clin Neurosci. 2003;5(3):207-21
Charney, D. S. (2003). The psychobiology of resilience and vulnerability to anxiety disorders: implications for prevention and treatment. Dialogues in clinical neuroscience, 5(3), 207-21.
Charney, Dennis S. "The psychobiology of resilience and vulnerability to anxiety disorders: implications for prevention and treatment." Dialogues in clinical neuroscience vol. 5,3 (2003): 207-21.
Charney DS. The psychobiology of resilience and vulnerability to anxiety disorders: implications for prevention and treatment. Dialogues Clin Neurosci. 2003 Sep;5(3):207-21. PMID: 22034473; PMCID: PMC3181630.
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In Response.

Anesthesia and analgesia

Peacock SC, Lovshin JA, Cherney DZI.
PMID: 29624534
Anesth Analg. 2018 Jul;127(1):307-308. doi: 10.1213/ANE.0000000000003350.

No abstract available.

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Peacock SC, Lovshin JA, Cherney DZI. In Response. Anesth Analg. 2018;127(1):307-308doi: 10.1213/ANE.0000000000003350.
Peacock, S. C., Lovshin, J. A., & Cherney, D. Z. I. (2018). In Response. Anesthesia and analgesia, 127(1), 307-308. https://doi.org/10.1213/ANE.0000000000003350
Peacock, Sharon C, et al. "In Response." Anesthesia and analgesia vol. 127,1 (2018): 307-308. doi: https://doi.org/10.1213/ANE.0000000000003350
Peacock SC, Lovshin JA, Cherney DZI. In Response. Anesth Analg. 2018 Jul;127(1):307-308. doi: 10.1213/ANE.0000000000003350. PMID: 29624534.
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Increasing aphasia treatment intensity in an acute inpatient rehabilitation program: A feasibility study.

Aphasiology

Carpenter J, Cherney LR.
PMID: 27026751
Aphasiology. 2016 May 01;30(5):542-565. doi: 10.1080/02687038.2015.1023695. Epub 2015 Mar 19.

BACKGROUND: Intensity of therapy is a critical factor influencing outcomes in aphasia. However, there are many barriers to increasing treatment intensity for those with acute/subacute aphasia including the demands of the inpatient medical facilities and the endurance of the...

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Carpenter J, Cherney LR. Increasing aphasia treatment intensity in an acute inpatient rehabilitation program: A feasibility study. Aphasiology. 2015;30(5):542-565doi: 10.1080/02687038.2015.1023695.
Carpenter, J., & Cherney, L. R. (2016). Increasing aphasia treatment intensity in an acute inpatient rehabilitation program: A feasibility study. Aphasiology, 30(5), 542-565. https://doi.org/10.1080/02687038.2015.1023695
Carpenter, Julia, and Cherney, Leora R. "Increasing aphasia treatment intensity in an acute inpatient rehabilitation program: A feasibility study." Aphasiology vol. 30,5 (2016): 542-565. doi: https://doi.org/10.1080/02687038.2015.1023695
Carpenter J, Cherney LR. Increasing aphasia treatment intensity in an acute inpatient rehabilitation program: A feasibility study. Aphasiology. 2016 May 01;30(5):542-565. doi: 10.1080/02687038.2015.1023695. Epub 2015 Mar 19. PMID: 27026751; PMCID: PMC4808295.
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Use of a Conformational-Switching Mechanism to Modulate Exposed Polarity: Discovery of CCR2 Antagonist BMS-741672.

ACS medicinal chemistry letters

Yang MG, Xiao Z, Cherney RJ, Tebben AJ, Batt DG, Brown GD, Chen J, Cvijic ME, Dabros M, Duncia JV, Galella M, Gardner DS, Khandelwal P, Ko SS, Malley MF, Mo R, Pang J, Rose AV, Santella JB, Shi H, Srivastava A, Traeger SC, Wang B, Xu S, Zhao R, Barrish JC, Mandlekar S, Zhao Q, Carter PH.
PMID: 30891130
ACS Med Chem Lett. 2019 Jan 16;10(3):300-305. doi: 10.1021/acsmedchemlett.8b00439. eCollection 2019 Mar 14.

We encountered a dilemma in the course of studying a series of antagonists of the G-protein coupled receptor CC chemokine receptor-2 (CCR2): compounds with polar C3 side chains exhibited good ion channel selectivity but poor oral bioavailability, whereas compounds...

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Yang MG, Xiao Z, Cherney RJ, et al. Use of a Conformational-Switching Mechanism to Modulate Exposed Polarity: Discovery of CCR2 Antagonist BMS-741672. ACS Med Chem Lett. 2019;10(3):300-305doi: 10.1021/acsmedchemlett.8b00439.
Yang, M. G., Xiao, Z., Cherney, R. J., Tebben, A. J., Batt, D. G., Brown, G. D., Chen, J., Cvijic, M. E., Dabros, M., Duncia, J. V., Galella, M., Gardner, D. S., Khandelwal, P., Ko, S. S., Malley, M. F., Mo, R., Pang, J., Rose, A. V., Santella, J. B., Shi, H., Srivastava, A., Traeger, S. C., Wang, B., Xu, S., Zhao, R., Barrish, J. C., Mandlekar, S., Zhao, Q., & Carter, P. H. (2019). Use of a Conformational-Switching Mechanism to Modulate Exposed Polarity: Discovery of CCR2 Antagonist BMS-741672. ACS medicinal chemistry letters, 10(3), 300-305. https://doi.org/10.1021/acsmedchemlett.8b00439
Yang, Michael G, et al. "Use of a Conformational-Switching Mechanism to Modulate Exposed Polarity: Discovery of CCR2 Antagonist BMS-741672." ACS medicinal chemistry letters vol. 10,3 (2019): 300-305. doi: https://doi.org/10.1021/acsmedchemlett.8b00439
Yang MG, Xiao Z, Cherney RJ, Tebben AJ, Batt DG, Brown GD, Chen J, Cvijic ME, Dabros M, Duncia JV, Galella M, Gardner DS, Khandelwal P, Ko SS, Malley MF, Mo R, Pang J, Rose AV, Santella JB, Shi H, Srivastava A, Traeger SC, Wang B, Xu S, Zhao R, Barrish JC, Mandlekar S, Zhao Q, Carter PH. Use of a Conformational-Switching Mechanism to Modulate Exposed Polarity: Discovery of CCR2 Antagonist BMS-741672. ACS Med Chem Lett. 2019 Jan 16;10(3):300-305. doi: 10.1021/acsmedchemlett.8b00439. eCollection 2019 Mar 14. PMID: 30891130; PMCID: PMC6421546.
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Showing 1 to 12 of 313 entries