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Cytotoxicity testing of beta-lactam antibiotics, non-steroidal anti-inflammatory drugs and sulfonamides in primary human keratinocyte cultures.

Toxicology in vitro : an international journal published in association with BIBRA

Patoux-Pibouin M, Hirel B, Chesne C, Watier E, Chevrant-Breton J, Guillouzo A.
PMID: 20650118
Toxicol In Vitro. 1995 Aug;9(4):493-7. doi: 10.1016/0887-2333(95)00020-9.

We have studied the cytotoxity to human keratinocytes of three main classes of drugs known to induce cutaneous adverse reactions, namely beta-lactam antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs) and sulfonamides, using the neutral red uptake as an endpoint. IC(50) values...

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