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Showing 1 to 12 of 111 entries
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Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening. Summary and recommendations.

European journal of human genetics : EJHG

Dondorp W, de Wert G, Bombard Y, Bianchi DW, Bergmann C, Borry P, Chitty LS, Fellmann F, Forzano F, Hall A, Henneman L, Howard HC, Lucassen A, Ormond K, Peterlin B, Radojkovic D, Rogowski W, Soller M, Tibben A, Tranebjærg L, van El CG, Cornel MC, Berggren KF.
PMID: 25828867
Eur J Hum Genet. 2015 Apr 01; doi: 10.1038/ejhg.2015.56. Epub 2015 Apr 01.

No abstract available.

Corrigendum: Sustainable, Rapid Synthesis of Bright-Luminescent CuInS2-ZnS Alloyed Nanocrystals: Multistage Nano-xenotoxicity Assessment and Intravital Fluorescence Bioimaging in Zebrafish-Embryos.

Scientific reports

Chetty SS, Praneetha S, Basu S, Sachidanandan C, Murugan AV.
PMID: 27345563
Sci Rep. 2016 Jun 27;6:28607. doi: 10.1038/srep28607.

No abstract available.

The differential diagnosis of enlarged hyperechogenic kidneys with normal or increased liquor volume: report of five cases and review of the literature.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology

Chitty LS, Griffin DR, Johnson P, Neales K.
PMID: 12797085
Ultrasound Obstet Gynecol. 1991 Mar 01;1(2):115-21. doi: 10.1046/j.1469-0705.1991.01020115.x.

We report five cases of enlarged, hyperechogenic kidneys detected prenatally where the liquor volume was normal or increased. The etiology was different in all cases and included infantile and adult polycystic kidney disease, Perlman syndrome, trisomy 13 and cystic...

Lead neurotoxicity: heme oxygenase and nitric oxide synthase activities in developing rat brain.

Neurotoxicity research

Reddy GR, Suresh A, Murthy KS, Chetty CS.
PMID: 12826491
Neurotox Res. 2002 Feb;4(1):33-9. doi: 10.1080/10298420290007600.

Chronic lead (Pb) exposure has been shown to result in cognitive deficits in children. Diffusible nitric oxide (NO) is a biological messenger known to regulate long-term potentiation (LTP) in the developing nervous system. Carbon monoxide (CO), as in the...

A HOSPITAL SHIP IN THE MEDITERRANEAN.

British medical journal

Chitty H.
PMID: 20767844
Br Med J. 1915 Oct 09;2(2858):529-31. doi: 10.1136/bmj.2.2858.529.

No abstract available.

Theoretical study of multispectral structured illumination for depth resolved imaging of non-stationary objects: focus on retinal imaging.

Biomedical optics express

Gruppetta S, Chetty S.
PMID: 21339871
Biomed Opt Express. 2011 Jan 05;2(2):255-63. doi: 10.1364/BOE.1.000255.

Current implementations of structured illumination microscopy for depth-resolved (three-dimensional) imaging have limitations that restrict its use; specifically, they are not applicable to non-stationary objects imaged with relatively poor condenser optics and in non-fluorescent mode. This includes in-vivo retinal imaging....

Updates in the Development of ImmunoRNases for the Selective Killing of Tumor Cells.

Biomedicines

Jordaan S, Akinrinmade OA, Nachreiner T, Cremer C, Naran K, Chetty S, Barth S.
PMID: 29510557
Biomedicines. 2018 Mar 05;6(1). doi: 10.3390/biomedicines6010028.

Targeted cancer therapy includes, amongst others, antibody-based delivery of toxic payloads to selectively eliminate tumor cells. This payload can be either a synthetic small molecule drug composing an antibody-drug conjugate (ADC) or a cytotoxic protein composing an immunotoxin (IT)....

Designing the Sniper: Improving Targeted Human Cytolytic Fusion Proteins for Anti-Cancer Therapy via Molecular Simulation.

Biomedicines

Bochicchio A, Jordaan S, Losasso V, Chetty S, Perera RC, Ippoliti E, Barth S, Carloni P.
PMID: 28536352
Biomedicines. 2017 Feb 17;5(1). doi: 10.3390/biomedicines5010009.

Targeted human cytolytic fusion proteins (hCFPs) are humanized immunotoxins for selective treatment of different diseases including cancer. They are composed of a ligand specifically binding to target cells genetically linked to a human apoptosis-inducing enzyme. hCFPs target cancer cells...

Human Granzyme B Based Targeted Cytolytic Fusion Proteins.

Biomedicines

Hlongwane P, Mungra N, Madheswaran S, Akinrinmade OA, Chetty S, Barth S.
PMID: 29925790
Biomedicines. 2018 Jun 20;6(2). doi: 10.3390/biomedicines6020072.

Cancer immunotherapy aims to selectively target and kill tumor cells whilst limiting the damage to healthy tissues. Controlled delivery of plant, bacterial and human toxins or enzymes has been shown to promote the induction of apoptosis in cancerous cells....

Acute Epiglottitis with Concurrent Pneumonia and Septic Shock in an Alcoholic Adult Patient.

Clinical practice and cases in emergency medicine

Chitty A, Taylor K.
PMID: 30443621
Clin Pract Cases Emerg Med. 2018 Oct 16;2(4):338-340. doi: 10.5811/cpcem.2018.9.39280. eCollection 2018 Nov.

Historically epiglottitis has been considered a childhood disease. However, the introduction of the

Aflibercept in Diabetic Macular Oedema Previously Refractory to Standard Intravitreal Therapy: An Irish Retrospective Study.

Ophthalmology and therapy

McCloskey CF, Mongan AM, Chetty S, McAteer DMJ, Quinn SM.
PMID: 29508370
Ophthalmol Ther. 2018 Jun;7(1):173-183. doi: 10.1007/s40123-018-0123-0. Epub 2018 Mar 05.

INTRODUCTION: To determine visual and anatomical outcomes of diabetic macular oedema (DMO) patients in a tertiary centre following conversion to aflibercept having been refractory to previous treatment with bevacizumab/ranibizumab.METHODS: A retrospective case series of patients with a diagnosis of...

A new way of teaching an old subject: Pharmacy Law and Ethics.

African journal of health professions education

Chetty S, Bangalee V, Oosthuizen F.
PMID: 30473874
Afr J Health Prof Educ. 2018;10(1):61-65. doi: 10.7196/AJHPE.2018.v10i1.714. Epub 2018 Apr 09.

BACKGROUND: Pharmacy educators are responsible for ensuring that students are equipped with the necessary regulatory knowledge required to deal with ethical challenges that arise in practice. Teaching methods have a strong impact on student learning, making it essential to...

Showing 1 to 12 of 111 entries