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Showing 1 to 12 of 209 entries
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Drug Normalization for Cancer Therapeutic and Druggable Genome Target Discovery.

AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Jiang G, Sohn S, Zimmermann MT, Wang C, Liu H, Chute CG.
PMID: 26306243
AMIA Jt Summits Transl Sci Proc. 2015 Mar 25;2015:72-6. eCollection 2015.

Heterogeneous drug data representation among different druggable genome knowledge resources and datasets delays effective cancer therapeutic target discovery within the broad scientific community. The objective of the present paper is to describe the challenges and lessons learned from our...

Granular Quality Reporting for Cervical Cytology Testing.

AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Wagholikar KB, MacLaughlin KL, Chute CG, Greenes RA, Liu H, Chaudhry R.
PMID: 26306264
AMIA Jt Summits Transl Sci Proc. 2015 Mar 25;2015:178-82. eCollection 2015.

Quality reporting for cervical cancer prevention is focused on patients with normal cervical cytology, and excludes patients with cytological abnormalities that may be at higher risk. The major obstacles for granular reporting are the complexity of surveillance guidelines and...

Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy.

Kidney international reports

Sise ME, Wisocky J, Rosales IA, Chute D, Holmes JA, Corapi KM, Babitt JL, Tangren JS, Hashemi N, Lundquist AL, Williams WW, Mount DB, Andersson KL, Rennke HG, Smith RN, Colvin R, Thadhani RI, Chung RT.
PMID: 27990496
Kidney Int Rep. 2016 Sep;1(3):135-143. doi: 10.1016/j.ekir.2016.06.006.

Novel, all-oral interferon-free direct-acting antiviral agents have revolutionized the management of hepatitis C virus (HCV) infection by producing exceptional cure rates with minimal adverse events. While provocation or exacerbation of autoimmunity has been reported in HCV-infected patients receiving interferon,...

A Framework of Knowledge Integration and Discovery for Supporting Pharmacogenomics Target Predication of Adverse Drug Events: A Case Study of Drug-Induced Long QT Syndrome.

AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Jiang G, Wang C, Zhu Q, Chute CG.
PMID: 24303306
AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:88-92. eCollection 2013.

Knowledge-driven text mining is becoming an important research area for identifying pharmacogenomics target genes. However, few of such studies have been focused on the pharmacogenomics targets of adverse drug events (ADEs). The objective of the present study is to...

Identifying Abdominal Aortic Aneurysm Cases and Controls using Natural Language Processing of Radiology Reports.

AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Sohn S, Ye Z, Liu H, Chute CG, Kullo IJ.
PMID: 24303276
AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:249-53. eCollection 2013.

Prevalence of abdominal aortic aneurysm (AAA) is increasing due to longer life expectancy and implementation of screening programs. Patient-specific longitudinal measurements of AAA are important to understand pathophysiology of disease development and modifiers of abdominal aortic size. In this...

Practical considerations in genomic decision support: The eMERGE experience.

Journal of pathology informatics

Herr TM, Bielinski SJ, Bottinger E, Brautbar A, Brilliant M, Chute CG, Cobb BL, Denny JC, Hakonarson H, Hartzler AL, Hripcsak G, Kannry J, Kohane IS, Kullo IJ, Lin S, Manzi S, Marsolo K, Overby CL, Pathak J, Peissig P, Pulley J, Ralston J, Rasmussen L, Roden DM, Tromp G, Uphoff T, Weng C, Wolf W, Williams MS, Starren J.
PMID: 26605115
J Pathol Inform. 2015 Sep 28;6:50. doi: 10.4103/2153-3539.165999. eCollection 2015.

BACKGROUND: Genomic medicine has the potential to improve care by tailoring treatments to the individual. There is consensus in the literature that pharmacogenomics (PGx) may be an ideal starting point for real-world implementation, due to the presence of well-characterized...

Fine needle aspiration biopsy of metastatic malignant mesothelioma with myxoid change and signet ring cells: A case report and review of the literature.

CytoJournal

Mishra MM, Farver CF, Chute DJ.
PMID: 27014364
Cytojournal. 2016 Feb 22;13:4. doi: 10.4103/1742-6413.177157. eCollection 2016.

Malignant mesothelioma (MM) is a rare neoplasm, which is most commonly encountered in cytology through effusion specimens. Fine needle aspiration biopsy of MM, particularly the epithelioid subtype, can be a source of diagnostic difficulty and may mimic sampling of...

The impact of weight gain associated with atypical antipsychotic use in schizophrenia.

Acta neuropsychiatrica

Chue P, Cheung R.
PMID: 26984162
Acta Neuropsychiatr. 2004 Jun;16(3):113-23. doi: 10.1111/j.0924-2708.2004.00067.x.

BACKGROUND: Atypical antipsychotics offer clear advantages in the management of schizophrenia, compared with conventional neuroleptics, but weight gain is a significant adverse effect with some of these agents.OBJECTIVE: To review the literature on weight gain associated with atypical antipsychotic...

Partial nephectomy.

The Journal of urology

CLARK FB, CHUTE R, RUDY HA.
PMID: 13163989
J Urol. 1954 Jul;72(1):6-15. doi: 10.1016/s0022-5347(17)67534-7.

No abstract available.

Seatbelts contribute to location of lesion in moderate to severe closed head trauma.

Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

Hillary F, Moelter ST, Schatz P, Chute DL.
PMID: 14590185
Arch Clin Neuropsychol. 2001 Feb;16(2):171-81.

The relationship between seatbelt use and injury severity, brain lesion location, and functional outcome was investigated in 163 individuals who sustained traumatic brain injuries in motor vehicle collisions. Of this group, 31 were using a seatbelt at the time...

Apollo 13 lunar heat flow experiment.

Science (New York, N.Y.)

Langseth MG, Wechsler AE, Drake EM, Simmons G, Clark SP, Chute J.
PMID: 17747091
Science. 1970 Apr 10;168(3928):211-7. doi: 10.1126/science.168.3928.211.

No abstract available.

Long-acting risperidone injection: efficacy, safety, and cost-effectiveness of the first long-acting atypical antipsychotic.

Neuropsychiatric disease and treatment

Chue P.
PMID: 19300536
Neuropsychiatr Dis Treat. 2007 Feb;3(1):13-39. doi: 10.2147/nedt.2007.3.1.13.

OBJECTIVE: To review the pharmacokinetics, efficacy, safety, and cost-effectiveness of long-acting risperidone.METHODS: Studies published between January 2000 and October 2006 evaluating the pharmacokinetics, efficacy, safety, and cost-effectiveness of long-acting risperidone were reviewed, as identified from literature searches using Medline...

Showing 1 to 12 of 209 entries