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Type 3 deiodinase: role in cancer growth, stemness, and metabolism.

Frontiers in endocrinology

Ciavardelli D, Bellomo M, Crescimanno C, Vella V.
PMID: 25566187
Front Endocrinol (Lausanne). 2014 Dec 17;5:215. doi: 10.3389/fendo.2014.00215. eCollection 2014.

Deiodinases are selenoenzymes that catalyze thyroid hormones (THs) activation (type 1 and type 2, D1 and D2, respectively) or inactivation (type 3, D3). THs are essential for proper body development and cellular differentiation. Their intra- and extra-cellular concentrations are...

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Ciavardelli D, Bellomo M, Crescimanno C, et al. Type 3 deiodinase: role in cancer growth, stemness, and metabolism. Front Endocrinol (Lausanne). 2014;5:215doi: 10.3389/fendo.2014.00215.
Ciavardelli, D., Bellomo, M., Crescimanno, C., & Vella, V. (2014). Type 3 deiodinase: role in cancer growth, stemness, and metabolism. Frontiers in endocrinology, 5215. https://doi.org/10.3389/fendo.2014.00215
Ciavardelli, Domenico, et al. "Type 3 deiodinase: role in cancer growth, stemness, and metabolism." Frontiers in endocrinology vol. 5 (2014): 215. doi: https://doi.org/10.3389/fendo.2014.00215
Ciavardelli D, Bellomo M, Crescimanno C, Vella V. Type 3 deiodinase: role in cancer growth, stemness, and metabolism. Front Endocrinol (Lausanne). 2014 Dec 17;5:215. doi: 10.3389/fendo.2014.00215. eCollection 2014. PMID: 25566187; PMCID: PMC4269192.
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Dentoskeletal modifications in Class II deep bite malocclusion treatment with anterior bite plane functional appliance.

Journal of clinical and experimental dentistry

Ciavarella D, Laurenziello M, Guida L, Montaruli G, Gallo C, Tepedino M, Lo Muzio L.
PMID: 28936295
J Clin Exp Dent. 2017 Aug 01;9(8):e1029-e1034. doi: 10.4317/jced.54092. eCollection 2017 Aug.

BACKGROUND: A treatment modality for Class II division 1 malocclusion is discussed. Orthodontic treatment of patients with deep bite and Class II malocclusion is an important challenge in clinical practice. The aim of this work is to compare the...

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Ciavarella D, Laurenziello M, Guida L, et al. Dentoskeletal modifications in Class II deep bite malocclusion treatment with anterior bite plane functional appliance. J Clin Exp Dent. 2017;9(8):e1029-e1034doi: 10.4317/jced.54092.
Ciavarella, D., Laurenziello, M., Guida, L., Montaruli, G., Gallo, C., Tepedino, M., & Lo Muzio, L. (2017). Dentoskeletal modifications in Class II deep bite malocclusion treatment with anterior bite plane functional appliance. Journal of clinical and experimental dentistry, 9(8), e1029-e1034. https://doi.org/10.4317/jced.54092
Ciavarella, Domenico, et al. "Dentoskeletal modifications in Class II deep bite malocclusion treatment with anterior bite plane functional appliance." Journal of clinical and experimental dentistry vol. 9,8 (2017): e1029-e1034. doi: https://doi.org/10.4317/jced.54092
Ciavarella D, Laurenziello M, Guida L, Montaruli G, Gallo C, Tepedino M, Lo Muzio L. Dentoskeletal modifications in Class II deep bite malocclusion treatment with anterior bite plane functional appliance. J Clin Exp Dent. 2017 Aug 01;9(8):e1029-e1034. doi: 10.4317/jced.54092. eCollection 2017 Aug. PMID: 28936295; PMCID: PMC5601104.
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Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients.

Molecular neurodegeneration

Zhong Z, Nural H, He P, Civarella G, Beach T, Sue L, Adler C, Shill H, Caviness J, Xia W, Shen Y.
PMID: 19604362
Mol Neurodegener. 2009 Jul 15;4:30. doi: 10.1186/1750-1326-4-30.

Correction to Nural H, He P, Beach T, Sue L, Xia W, Shen Y. Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients Molecular Neurodegeneration 2009, 4:23.

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Zhong Z, Nural H, He P, et al. Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients. Mol Neurodegener. 2009;4:30doi: 10.1186/1750-1326-4-30.
Zhong, Z., Nural, H., He, P., Civarella, G., Beach, T., Sue, L., Adler, C., Shill, H., Caviness, J., Xia, W., & Shen, Y. (2009). Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients. Molecular neurodegeneration, 430. https://doi.org/10.1186/1750-1326-4-30
Zhong, Zhenyu, et al. "Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients." Molecular neurodegeneration vol. 4 (2009): 30. doi: https://doi.org/10.1186/1750-1326-4-30
Zhong Z, Nural H, He P, Civarella G, Beach T, Sue L, Adler C, Shill H, Caviness J, Xia W, Shen Y. Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients. Mol Neurodegener. 2009 Jul 15;4:30. doi: 10.1186/1750-1326-4-30. PMID: 19604362; PMCID: PMC2722623.
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Blowing dust and highway safety in the southwestern United States: Characteristics of dust emission "hotspots" and management implications.

The Science of the total environment

Li J, Kandakji T, Lee JA, Tatarko J, Blackwell J, Gill TE, Collins JD, Lavezzo E, Ciavarella C.
PMID: 29102198
Sci Total Environ. 2018 Apr 15;621:1023-1032. doi: 10.1016/j.scitotenv.2017.10.124. Epub 2017 Nov 06.

Despite the widespread media attention of chain-reaction traffic incidents and property damage caused by windblown dust in the U.S. and elsewhere in the world, very few studies have provided in-depth analysis on this issue. Remote sensing and field observations...

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Li J, Kandakji T, Lee JA, et al. Blowing dust and highway safety in the southwestern United States: Characteristics of dust emission "hotspots" and management implications. Sci Total Environ. 2017;621:1023-1032doi: 10.1016/j.scitotenv.2017.10.124.
Li, J., Kandakji, T., Lee, J. A., Tatarko, J., Blackwell, J., Gill, T. E., Collins, J. D., Lavezzo, E., & Ciavarella, C. (2018). Blowing dust and highway safety in the southwestern United States: Characteristics of dust emission "hotspots" and management implications. The Science of the total environment, 6211023-1032. https://doi.org/10.1016/j.scitotenv.2017.10.124
Li, Junran, et al. "Blowing dust and highway safety in the southwestern United States: Characteristics of dust emission "hotspots" and management implications." The Science of the total environment vol. 621 (2018): 1023-1032. doi: https://doi.org/10.1016/j.scitotenv.2017.10.124
Li J, Kandakji T, Lee JA, Tatarko J, Blackwell J, Gill TE, Collins JD, Lavezzo E, Ciavarella C. Blowing dust and highway safety in the southwestern United States: Characteristics of dust emission "hotspots" and management implications. Sci Total Environ. 2018 Apr 15;621:1023-1032. doi: 10.1016/j.scitotenv.2017.10.124. Epub 2017 Nov 06. PMID: 29102198.
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Lung metastasectomy following kidney tumors: outcomes and prognostic factors from a single-center experience.

Journal of thoracic disease

Meacci E, Nachira D, Congedo MT, Porziella V, Chiappetta M, Ferretti G, Iaffaldano A, Ciavarella LP, Margaritora S.
PMID: 29119013
J Thorac Dis. 2017 Oct;9:S1267-S1272. doi: 10.21037/jtd.2017.05.04.

BACKGROUND: The lung is one of the sites most frequently affected by metastatic renal cell carcinoma (mRCC). Nonsurgical therapy for mRCC has limited efficacy, while the 5-year survival rates data published in literature after pulmonary surgery for metastasectomy, emphasize...

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Meacci E, Nachira D, Congedo MT, et al. Lung metastasectomy following kidney tumors: outcomes and prognostic factors from a single-center experience. J Thorac Dis. 2017;9:S1267-S1272doi: 10.21037/jtd.2017.05.04.
Meacci, E., Nachira, D., Congedo, M. T., Porziella, V., Chiappetta, M., Ferretti, G., Iaffaldano, A., Ciavarella, L. P., & Margaritora, S. (2017). Lung metastasectomy following kidney tumors: outcomes and prognostic factors from a single-center experience. Journal of thoracic disease, 9S1267-S1272. https://doi.org/10.21037/jtd.2017.05.04
Meacci, Elisa, et al. "Lung metastasectomy following kidney tumors: outcomes and prognostic factors from a single-center experience." Journal of thoracic disease vol. 9 (2017): S1267-S1272. doi: https://doi.org/10.21037/jtd.2017.05.04
Meacci E, Nachira D, Congedo MT, Porziella V, Chiappetta M, Ferretti G, Iaffaldano A, Ciavarella LP, Margaritora S. Lung metastasectomy following kidney tumors: outcomes and prognostic factors from a single-center experience. J Thorac Dis. 2017 Oct;9:S1267-S1272. doi: 10.21037/jtd.2017.05.04. PMID: 29119013; PMCID: PMC5653499.
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Dissection of DLBCL microenvironment provides a gene expression-based predictor of survival applicable to formalin-fixed paraffin-embedded tissue.

Annals of oncology : official journal of the European Society for Medical Oncology

Ciavarella S, Vegliante MC, Fabbri M, De Summa S, Melle F, Motta G, De Iuliis V, Opinto G, Enjuanes A, Rega S, Gulino A, Agostinelli C, Scattone A, Tommasi S, Mangia A, Mele F, Simone G, Zito AF, Ingravallo G, Vitolo U, Chiappella A, Tarella C, Gianni AM, Rambaldi A, Zinzani PL, Casadei B, Derenzini E, Loseto G, Pileri A, Tabanelli V, Fiori S, Rivas-Delgado A, López-Guillermo A, Venesio T, Sapino A, Campo E, Tripodo C, Guarini A, Pileri SA.
PMID: 31539020
Ann Oncol. 2019 Dec 01;30(12):2015. doi: 10.1093/annonc/mdz386.

No abstract available.

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Ciavarella S, Vegliante MC, Fabbri M, et al. Dissection of DLBCL microenvironment provides a gene expression-based predictor of survival applicable to formalin-fixed paraffin-embedded tissue. Ann Oncol. 2019;30(12):2015doi: 10.1093/annonc/mdz386.
Ciavarella, S., Vegliante, M. C., Fabbri, M., De Summa, S., Melle, F., Motta, G., De Iuliis, V., Opinto, G., Enjuanes, A., Rega, S., Gulino, A., Agostinelli, C., Scattone, A., Tommasi, S., Mangia, A., Mele, F., Simone, G., Zito, A. F., Ingravallo, G., Vitolo, U., Chiappella, A., Tarella, C., Gianni, A. M., Rambaldi, A., Zinzani, P. L., Casadei, B., Derenzini, E., Loseto, G., Pileri, A., Tabanelli, V., Fiori, S., Rivas-Delgado, A., López-Guillermo, A., Venesio, T., Sapino, A., Campo, E., Tripodo, C., Guarini, A., & Pileri, S. A. (2019). Dissection of DLBCL microenvironment provides a gene expression-based predictor of survival applicable to formalin-fixed paraffin-embedded tissue. Annals of oncology : official journal of the European Society for Medical Oncology, 30(12), 2015. https://doi.org/10.1093/annonc/mdz386
Ciavarella, S, et al. "Dissection of DLBCL microenvironment provides a gene expression-based predictor of survival applicable to formalin-fixed paraffin-embedded tissue." Annals of oncology : official journal of the European Society for Medical Oncology vol. 30,12 (2019): 2015. doi: https://doi.org/10.1093/annonc/mdz386
Ciavarella S, Vegliante MC, Fabbri M, De Summa S, Melle F, Motta G, De Iuliis V, Opinto G, Enjuanes A, Rega S, Gulino A, Agostinelli C, Scattone A, Tommasi S, Mangia A, Mele F, Simone G, Zito AF, Ingravallo G, Vitolo U, Chiappella A, Tarella C, Gianni AM, Rambaldi A, Zinzani PL, Casadei B, Derenzini E, Loseto G, Pileri A, Tabanelli V, Fiori S, Rivas-Delgado A, López-Guillermo A, Venesio T, Sapino A, Campo E, Tripodo C, Guarini A, Pileri SA. Dissection of DLBCL microenvironment provides a gene expression-based predictor of survival applicable to formalin-fixed paraffin-embedded tissue. Ann Oncol. 2019 Dec 01;30(12):2015. doi: 10.1093/annonc/mdz386. PMID: 31539020; PMCID: PMC6938597.
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Perceptual learning improves visual functions in patients with albinistic bilateral amblyopia: A pilot study.

Restorative neurology and neuroscience

Battaglini L, Oletto CM, Contemori G, Barollo M, Ciavarelli A, Casco C.
PMID: 33554927
Restor Neurol Neurosci. 2021;39(1):45-59. doi: 10.3233/RNN-201043.

BACKGROUND: Several visual functions are impaired in patients with oculocutaneous albinism (OCA) associated to albinistic bilateral amblyopia (ABA).OBJECTIVE: In this study, we aimed at exploring whether perceptual learning (PL) can improve visual functions in albinism.METHOD: Six patients and six...

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Battaglini L, Oletto CM, Contemori G, et al. Perceptual learning improves visual functions in patients with albinistic bilateral amblyopia: A pilot study. Restor Neurol Neurosci. 2021;39(1):45-59doi: 10.3233/RNN-201043.
Battaglini, L., Oletto, C. M., Contemori, G., Barollo, M., Ciavarelli, A., & Casco, C. (2021). Perceptual learning improves visual functions in patients with albinistic bilateral amblyopia: A pilot study. Restorative neurology and neuroscience, 39(1), 45-59. https://doi.org/10.3233/RNN-201043
Battaglini, Luca, et al. "Perceptual learning improves visual functions in patients with albinistic bilateral amblyopia: A pilot study." Restorative neurology and neuroscience vol. 39,1 (2021): 45-59. doi: https://doi.org/10.3233/RNN-201043
Battaglini L, Oletto CM, Contemori G, Barollo M, Ciavarelli A, Casco C. Perceptual learning improves visual functions in patients with albinistic bilateral amblyopia: A pilot study. Restor Neurol Neurosci. 2021;39(1):45-59. doi: 10.3233/RNN-201043. PMID: 33554927.
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MicroRNA profiles of human peripheral arteries and abdominal aorta in normal conditions: MicroRNAs-27a-5p, -139-5p and -155-5p emerge and in atheroma too.

Mechanisms of ageing and development

Collura S, Ciavarella C, Morsiani C, Motta I, Valente S, Gallitto E, Abualhin M, Pini R, Vasuri F, Franceschi C, Capri M, Gargiulo M, Pasquinelli G.
PMID: 34329656
Mech Ageing Dev. 2021 Sep;198:111547. doi: 10.1016/j.mad.2021.111547. Epub 2021 Jul 28.

Atherosclerosis may starts early in life and each artery has peculiar characteristics likely affecting atherogenesis. The primary objective of the work was to underpin the microRNA (miR)-profiling differences in human normal femoral, abdominal aortic, and carotid arteries. The secondary...

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Collura S, Ciavarella C, Morsiani C, et al. MicroRNA profiles of human peripheral arteries and abdominal aorta in normal conditions: MicroRNAs-27a-5p, -139-5p and -155-5p emerge and in atheroma too. Mech Ageing Dev. 2021;198:111547doi: 10.1016/j.mad.2021.111547.
Collura, S., Ciavarella, C., Morsiani, C., Motta, I., Valente, S., Gallitto, E., Abualhin, M., Pini, R., Vasuri, F., Franceschi, C., Capri, M., Gargiulo, M., & Pasquinelli, G. (2021). MicroRNA profiles of human peripheral arteries and abdominal aorta in normal conditions: MicroRNAs-27a-5p, -139-5p and -155-5p emerge and in atheroma too. Mechanisms of ageing and development, 198111547. https://doi.org/10.1016/j.mad.2021.111547
Collura, Salvatore, et al. "MicroRNA profiles of human peripheral arteries and abdominal aorta in normal conditions: MicroRNAs-27a-5p, -139-5p and -155-5p emerge and in atheroma too." Mechanisms of ageing and development vol. 198 (2021): 111547. doi: https://doi.org/10.1016/j.mad.2021.111547
Collura S, Ciavarella C, Morsiani C, Motta I, Valente S, Gallitto E, Abualhin M, Pini R, Vasuri F, Franceschi C, Capri M, Gargiulo M, Pasquinelli G. MicroRNA profiles of human peripheral arteries and abdominal aorta in normal conditions: MicroRNAs-27a-5p, -139-5p and -155-5p emerge and in atheroma too. Mech Ageing Dev. 2021 Sep;198:111547. doi: 10.1016/j.mad.2021.111547. Epub 2021 Jul 28. PMID: 34329656.
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Taxonomic Analysis of Oral Microbiome during Orthodontic Treatment.

International journal of dentistry

Campobasso A, Lo Muzio E, Battista G, Ciavarella D, Crincoli V, Lo Muzio L.
PMID: 34745264
Int J Dent. 2021 Oct 28;2021:8275181. doi: 10.1155/2021/8275181. eCollection 2021.

BACKGROUND: Orthodontic appliances induce significant changes in the oral microbiome, but this shift in microbial composition has not been well established by the available evidence yet.OBJECTIVES: To perform a systematic review of existing literature in order to assess the...

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Campobasso A, Lo Muzio E, Battista G, et al. Taxonomic Analysis of Oral Microbiome during Orthodontic Treatment. Int J Dent. 2021;2021:8275181doi: 10.1155/2021/8275181.
Campobasso, A., Lo Muzio, E., Battista, G., Ciavarella, D., Crincoli, V., & Lo Muzio, L. (2021). Taxonomic Analysis of Oral Microbiome during Orthodontic Treatment. International journal of dentistry, 20218275181. https://doi.org/10.1155/2021/8275181
Campobasso, Alessandra, et al. "Taxonomic Analysis of Oral Microbiome during Orthodontic Treatment." International journal of dentistry vol. 2021 (2021): 8275181. doi: https://doi.org/10.1155/2021/8275181
Campobasso A, Lo Muzio E, Battista G, Ciavarella D, Crincoli V, Lo Muzio L. Taxonomic Analysis of Oral Microbiome during Orthodontic Treatment. Int J Dent. 2021 Oct 28;2021:8275181. doi: 10.1155/2021/8275181. eCollection 2021. PMID: 34745264; PMCID: PMC8568516.
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Hodgkin Lymphoma: A Special Microenvironment.

Journal of clinical medicine

Opinto G, Agostinelli C, Ciavarella S, Guarini A, Maiorano E, Ingravallo G.
PMID: 34682791
J Clin Med. 2021 Oct 12;10(20). doi: 10.3390/jcm10204665.

Classical Hodgkin's lymphoma (cHL) is one of the most particular lymphomas for the few tumor cells surrounded by an inflammatory microenvironment. Reed-Sternberg (RS) and Hodgkin (H) cells reprogram and evade antitumor mechanisms of the normal cells present in the...

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Opinto G, Agostinelli C, Ciavarella S, et al. Hodgkin Lymphoma: A Special Microenvironment. J Clin Med. 2021;10(20)doi: 10.3390/jcm10204665.
Opinto, G., Agostinelli, C., Ciavarella, S., Guarini, A., Maiorano, E., & Ingravallo, G. (2021). Hodgkin Lymphoma: A Special Microenvironment. Journal of clinical medicine, 10(20), . https://doi.org/10.3390/jcm10204665
Opinto, Giuseppina, et al. "Hodgkin Lymphoma: A Special Microenvironment." Journal of clinical medicine vol. 10,20 (2021). doi: https://doi.org/10.3390/jcm10204665
Opinto G, Agostinelli C, Ciavarella S, Guarini A, Maiorano E, Ingravallo G. Hodgkin Lymphoma: A Special Microenvironment. J Clin Med. 2021 Oct 12;10(20). doi: 10.3390/jcm10204665. PMID: 34682791; PMCID: PMC8541076.
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Prolonged Siberian heat of 2020 almost impossible without human influence.

Climatic change

Ciavarella A, Cotterill D, Stott P, Kew S, Philip S, van Oldenborgh GJ, Skålevåg A, Lorenz P, Robin Y, Otto F, Hauser M, Seneviratne SI, Lehner F, Zolina O.
PMID: 34720262
Clim Change. 2021;166(1):9. doi: 10.1007/s10584-021-03052-w. Epub 2021 May 06.

Over the first half of 2020, Siberia experienced the warmest period from January to June since records began and on the 20th of June the weather station at Verkhoyansk reported 38 °C, the highest daily maximum temperature recorded north...

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Ciavarella A, Cotterill D, Stott P, et al. Prolonged Siberian heat of 2020 almost impossible without human influence. Clim Change. 2021;166(1):9doi: 10.1007/s10584-021-03052-w.
Ciavarella, A., Cotterill, D., Stott, P., Kew, S., Philip, S., van Oldenborgh, G. J., Skålevåg, A., Lorenz, P., Robin, Y., Otto, F., Hauser, M., Seneviratne, S. I., Lehner, F., & Zolina, O. (2021). Prolonged Siberian heat of 2020 almost impossible without human influence. Climatic change, 166(1), 9. https://doi.org/10.1007/s10584-021-03052-w
Ciavarella, Andrew, et al. "Prolonged Siberian heat of 2020 almost impossible without human influence." Climatic change vol. 166,1 (2021): 9. doi: https://doi.org/10.1007/s10584-021-03052-w
Ciavarella A, Cotterill D, Stott P, Kew S, Philip S, van Oldenborgh GJ, Skålevåg A, Lorenz P, Robin Y, Otto F, Hauser M, Seneviratne SI, Lehner F, Zolina O. Prolonged Siberian heat of 2020 almost impossible without human influence. Clim Change. 2021;166(1):9. doi: 10.1007/s10584-021-03052-w. Epub 2021 May 06. PMID: 34720262; PMCID: PMC8550097.
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De Novo Inverted Duplication Deletion of 4p in a 14-Week-Old Male Fetus Aborted Due to Multiple Anomalies.

Journal of pediatric genetics

Fontana P, Bernardini L, Lombardi C, Giuffrida MG, Ciavarella M, Capalbo A, Maioli M, Scarano F, Cantalupo G, Falco M, Scarano G, Lonardo F.
PMID: 34504730
J Pediatr Genet. 2021 Sep;10(3):245-249. doi: 10.1055/s-0040-1713156. Epub 2020 Jun 19.

Inverted duplications deletions are rare, complex, and nonrecurrent chromosomal rearrangements associated with a variable phenotype. In this case report, we described the phenotype and genotype of a 14-week-old male fetus, who was aborted after discovery of multiple anomalies (septal...

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Fontana P, Bernardini L, Lombardi C, et al. De Novo Inverted Duplication Deletion of 4p in a 14-Week-Old Male Fetus Aborted Due to Multiple Anomalies. J Pediatr Genet. 2020;10(3):245-249doi: 10.1055/s-0040-1713156.
Fontana, P., Bernardini, L., Lombardi, C., Giuffrida, M. G., Ciavarella, M., Capalbo, A., Maioli, M., Scarano, F., Cantalupo, G., Falco, M., Scarano, G., & Lonardo, F. (2021). De Novo Inverted Duplication Deletion of 4p in a 14-Week-Old Male Fetus Aborted Due to Multiple Anomalies. Journal of pediatric genetics, 10(3), 245-249. https://doi.org/10.1055/s-0040-1713156
Fontana, Paolo, et al. "De Novo Inverted Duplication Deletion of 4p in a 14-Week-Old Male Fetus Aborted Due to Multiple Anomalies." Journal of pediatric genetics vol. 10,3 (2021): 245-249. doi: https://doi.org/10.1055/s-0040-1713156
Fontana P, Bernardini L, Lombardi C, Giuffrida MG, Ciavarella M, Capalbo A, Maioli M, Scarano F, Cantalupo G, Falco M, Scarano G, Lonardo F. De Novo Inverted Duplication Deletion of 4p in a 14-Week-Old Male Fetus Aborted Due to Multiple Anomalies. J Pediatr Genet. 2021 Sep;10(3):245-249. doi: 10.1055/s-0040-1713156. Epub 2020 Jun 19. PMID: 34504730; PMCID: PMC8416190.
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