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Showing 1 to 12 of 22 entries
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Intravenous immune globulin suppresses angiogenesis in mice and humans.

Signal transduction and targeted therapy

Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J.
PMID: 26925256
Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.2. Epub 2016 Jan 28.

Human intravenous immune globulin (IVIg), a purified IgG fraction composed of ~ 60% IgG1 and obtained from the pooled plasma of thousands of donors, is clinically used for a wide range of diseases. The biological actions of IVIg are...

Prenatally diagnosed distal 16p11.2 microdeletion with a novel association with congenital diaphragmatic hernia: a case report.

Clinical case reports

Genesio R, Maruotti GM, Saccone G, Mormile A, Conti A, Cicatiello R, Sarnataro V, Sirico A, Izzo A, Martinelli P, Nitsch L.
PMID: 29636920
Clin Case Rep. 2018 Feb 09;6(4):592-595. doi: 10.1002/ccr3.1369. eCollection 2018 Apr.

A prenatal case presenting with congenital diaphragmatic hernia (CDH) and distal 16p11.2 microdeletion suggests two possible causative hypotheses: (1) a functional effect of chromatin loopings between the distal and the proximal 16p11.2 microdeletion traits, associated with CHD; (2) a...

Complementary Metal-Oxide-Semiconductor Potentiometric Field-Effect Transistor Array Platform Using Sensor Learning for Multi-ion Imaging.

Analytical chemistry

Moser N, Leong CL, Hu Y, Cicatiello C, Gowers S, Boutelle M, Georgiou P.
PMID: 32142259
Anal Chem. 2020 Apr 07;92(7):5276-5285. doi: 10.1021/acs.analchem.9b05836. Epub 2020 Mar 20.

This work describes an array of 1024 ion-sensitive field-effect transistors (ISFETs) using sensor-learning techniques to perform multi-ion imaging for concurrent detection of potassium, sodium, calcium, and hydrogen. Analyte-specific ionophore membranes are deposited on the surface of the ISFET array...

Thyroid Hormone Enhances Angiogenesis and the Warburg Effect in Squamous Cell Carcinomas.

Cancers

Miro C, Nappi A, Cicatiello AG, Di Cicco E, Sagliocchi S, Murolo M, Belli V, Troiani T, Albanese S, Amiranda S, Zavacki AM, Stornaiuolo M, Mancini M, Salvatore D, Dentice M.
PMID: 34205977
Cancers (Basel). 2021 Jun 01;13(11). doi: 10.3390/cancers13112743.

Cancer angiogenesis is required to support energetic demand and metabolic stress, particularly during conditions of hypoxia. Coupled to neo-vasculogenesis, cancer cells rewire metabolic programs to sustain growth, survival and long-term maintenance. Thyroid hormone (TH) signaling regulates growth and differentiation...

A Pictorial Review of the Role of Imaging in the Detection, Management, Histopathological Correlations, and Complications of COVID-19 Pneumonia.

Diagnostics (Basel, Switzerland)

Brogna B, Bignardi E, Brogna C, Volpe M, Lombardi G, Rosa A, Gagliardi G, Capasso PFM, Gravino E, Maio F, Pane F, Picariello V, Buono M, Colucci L, Musto LA.
PMID: 33806423
Diagnostics (Basel). 2021 Mar 04;11(3). doi: 10.3390/diagnostics11030437.

Imaging plays an important role in the detection of coronavirus (COVID-19) pneumonia in both managing the disease and evaluating the complications. Imaging with chest computed tomography (CT) can also have a potential predictive and prognostic role in COVID-19 patient...

Corrigendum: Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells.

Frontiers in genetics

Mollo N, Nitti M, Zerillo L, Faicchia D, Micillo T, Accarino R, Secondo A, Petrozziello T, Calì G, Cicatiello R, Bonfiglio F, Sarnataro V, Genesio R, Izzo A, Pinton P, Matarese G, Paladino S, Conti A, Nitsch L.
PMID: 32849775
Front Genet. 2020 Jul 27;11:728. doi: 10.3389/fgene.2020.00728. eCollection 2020.

[This corrects the article DOI: 10.3389/fgene.2019.00606.].

Persistence of Anti-SARS-CoV-2 Antibodies in Non-Hospitalized COVID-19 Convalescent Health Care Workers.

Journal of clinical medicine

Bruni M, Cecatiello V, Diaz-Basabe A, Lattanzi G, Mileti E, Monzani S, Pirovano L, Rizzelli F, Visintin C, Bonizzi G, Giani M, Lavitrano M, Faravelli S, Forneris F, Caprioli F, Pelicci PG, Natoli G, Pasqualato S, Mapelli M, Facciotti F.
PMID: 33019628
J Clin Med. 2020 Oct 01;9(10). doi: 10.3390/jcm9103188.

Although antibody response to SARS-CoV-2 can be detected early during the infection, several outstanding questions remain to be addressed regarding the magnitude and persistence of antibody titer against different viral proteins and their correlation with the strength of the...

Chromosomal Microarray Analysis versus Karyotyping in Fetuses with Increased Nuchal Translucency.

Medical sciences (Basel, Switzerland)

Cicatiello R, Pignataro P, Izzo A, Mollo N, Pezone L, Maruotti GM, Sarno L, Sglavo G, Conti A, Genesio R, Nitsch L.
PMID: 30818867
Med Sci (Basel). 2019 Feb 27;7(3). doi: 10.3390/medsci7030040.

We have carried out a retrospective study of chromosome anomalies associated with increased nuchal translucency (NT) in order to compare yield rates of karyotype, chromosome microarray analysis (CMA), and non-invasive prenatal testing (NIPT) in this condition. Presenting with increased...

Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells.

Frontiers in genetics

Mollo N, Nitti M, Zerillo L, Faicchia D, Micillo T, Accarino R, Secondo A, Petrozziello T, Calì G, Cicatiello R, Bonfiglio F, Sarnataro V, Genesio R, Izzo A, Pinton P, Matarese G, Paladino S, Conti A, Nitsch L.
PMID: 31316549
Front Genet. 2019 Jun 28;10:606. doi: 10.3389/fgene.2019.00606. eCollection 2019.

Mitochondrial dysfunction plays a primary role in neurodevelopmental anomalies and neurodegeneration of Down syndrome (DS) subjects. For this reason, targeting mitochondrial key genes, such as

The growth of marine fungi on seaweed polysaccharides produces cerato-platanin and hydrophobin self-assembling proteins.

Microbiological research

Landeta-Salgado C, Cicatiello P, Stanzione I, Medina D, Berlanga Mora I, Gomez C, Lienqueo ME.
PMID: 34399103
Microbiol Res. 2021 Oct;251:126835. doi: 10.1016/j.micres.2021.126835. Epub 2021 Aug 05.

The marine fungi Paradendryphiela salina and Talaromyces pinophilus degrade and assimilate complex substrates from plants and seaweed. Additionally, these fungi secrete surface-active proteins, identified as cerato-platanins and hydrophobins. These hydrophobic proteins have the ability to self-assemble forming amyloid-like aggregates...

Molecular bases of copper and iron deficiency-associated dyslipidemia: a microarray analysis of the rat intestinal transcriptome.

Genes & nutrition

Tosco A, Fontanella B, Danise R, Cicatiello L, Grober OM, Ravo M, Weisz A, Marzullo L.
PMID: 19821111
Genes Nutr. 2010 Mar;5(1):1-8. doi: 10.1007/s12263-009-0153-2. Epub 2009 Oct 11.

As essential cofactor in many proteins and redox enzymes, copper and iron are involved in a wide range of biological processes. Mild dietary deficiency of metals represents an underestimated problem for human health, because it does not cause clear...

Overexpression of Chromosome 21 miRNAs May Affect Mitochondrial Function in the Hearts of Down Syndrome Fetuses.

International journal of genomics

Izzo A, Manco R, de Cristofaro T, Bonfiglio F, Cicatiello R, Mollo N, De Martino M, Genesio R, Zannini M, Conti A, Nitsch L.
PMID: 29057256
Int J Genomics. 2017;2017:8737649. doi: 10.1155/2017/8737649. Epub 2017 Sep 05.

Dosage-dependent upregulation of most of chromosome 21 (Hsa21) genes has been demonstrated in heart tissues of fetuses with Down syndrome (DS). Also miRNAs might play important roles in the cardiac phenotype as they are highly expressed in the heart...

Showing 1 to 12 of 22 entries