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Showing 1 to 12 of 211 entries
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Germline whole exome sequencing and large-scale replication identifies .

Oncotarget

Dicks E, Song H, Ramus SJ, Oudenhove EV, Tyrer JP, Intermaggio MP, Kar S, Harrington P, Bowtell DD, Group AS, Cicek MS, Cunningham JM, Fridley BL, Alsop J, Jimenez-Linan M, Piskorz A, Goranova T, Kent E, Siddiqui N, Paul J, Crawford R, Poblete S, Lele S, Sucheston-Campbell L, Moysich KB, Sieh W, McGuire V, Lester J, Odunsi K, Whittemore AS, Bogdanova N, Dürst M, Hillemanns P, Karlan BY, Gentry-Maharaj A, Menon U, Tischkowitz M, Levine D, Brenton JD, Dörk T, Goode EL, Gayther SA, Pharoah DPP.
PMID: 28881617
Oncotarget. 2017 Mar 03;8(31):50930-50940. doi: 10.18632/oncotarget.15871. eCollection 2017 Aug 01.

We analyzed whole exome sequencing data in germline DNA from 412 high grade serous ovarian cancer (HGSOC) cases from The Cancer Genome Atlas Project and identified 5,517 genes harboring a predicted deleterious germline coding mutation in at least one...

Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition.

Oncotarget

Nguyen A, Moussallieh FM, Mackay A, Cicek AE, Coca A, Chenard MP, Weingertner N, Lhermitte B, Letouzé E, Guérin E, Pencreach E, Jannier S, Guenot D, Namer IJ, Jones C, Entz-Werlé N.
PMID: 29069732
Oncotarget. 2017 Mar 23;8(42):71597-71617. doi: 10.18632/oncotarget.16500. eCollection 2017 Sep 22.

Pediatric high grade glioma (pHGGs), including sus-tentorial and diffuse intrinsic pontine gliomas, are known to have a very dismal prognosis. For instance, even an increased knowledge on molecular biology driving this brain tumor entity, there is no treatment able...

Comparing the Effect of Different Voxel Resolutions for Assessment of Vertical Root Fracture of Permanent Teeth.

Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society

Uzun I, Gunduz K, Celenk P, Avsever H, Orhan K, Canitezer G, Ozmen B, Cicek E, Egrioglu E.
PMID: 26557279
Iran J Radiol. 2015 Jul 22;12(3):e18290. doi: 10.5812/iranjradiol.18290. eCollection 2015 Jul.

BACKGROUND: The teeth with undiagnosed vertical root fractures (VRFs) are likely to receive endodontic treatment or retreatment, leading to frustration and inappropriate endodontic therapies. Moreover, many cases of VRFs cannot be diagnosed definitively until the extraction of tooth.OBJECTIVES: This...

A new approach to determine the capture conditions of bark beetles in pheromone-baited traps.

Biotechnology, biotechnological equipment

Ozcan GE, Cicek O, Enez K, Yildiz M.
PMID: 26019592
Biotechnol Biotechnol Equip. 2014 Nov 02;28(6):1057-1064. doi: 10.1080/13102818.2014.974015. Epub 2014 Nov 12.

Forests form an organic unity with a great number of organic and inorganic components and tend to maintain the sustainability of their existing balance. However, some factors which adversely affect the balance of nature may interrupt this sustainability. The...

Is there any superiority among diagnostic methods in organizing pneumonia in terms of clinical features of the patients?.

Therapeutics and clinical risk management

Kavakli K, Ocal N, Dogan D, Cicek AF, Isik H, Gurkok S.
PMID: 27713632
Ther Clin Risk Manag. 2016 Sep 26;12:1473-1479. doi: 10.2147/TCRM.S108037. eCollection 2016.

BACKGROUND: Organizing pneumonia (OP) can be idiopathic or secondary to some clinical situations. If an etiological cause is not present, this phenomenon is called cryptogenic OP. Secondary OP is associated with various diseases that are known to induce the...

Echo-Doppler determinants of outcomes in patients with unoperated significant mitral regurgitation in current era.

Open heart

Rafique AM, Zarrini P, Singh N, Beigel R, Tadwalkar R, Chonde M, Slipczuk L, Cercek B, Kar S, Siegel RJ.
PMID: 27547425
Open Heart. 2016 Aug 01;3(2):e000378. doi: 10.1136/openhrt-2015-000378. eCollection 2016.

OBJECTIVE: One-half of patients with severe symptomatic mitral regurgitation (MR) do not undergo surgery due to comorbidities. We evaluated prognosticators of outcomes in patients with unoperated significant MR.METHODS: In this observational study, we retrospectively evaluated medical records of 75...

Food consumption and the actual statistics of cardiovascular diseases: an epidemiological comparison of 42 European countries.

Food & nutrition research

Grasgruber P, Sebera M, Hrazdira E, Hrebickova S, Cacek J.
PMID: 27680091
Food Nutr Res. 2016 Sep 27;60:31694. doi: 10.3402/fnr.v60.31694. eCollection 2016.

BACKGROUND: The aim of this ecological study was to identify the main nutritional factors related to the prevalence of cardiovascular diseases (CVDs) in Europe, based on a comparison of international statistics.DESIGN: The mean consumption of 62 food items from...

Hepatitis C virus positive patient diagnosed after detection of atypical cryoglobulin.

World journal of clinical cases

Ongen B, Aksungar FB, Cicek B, Akyar I, Coskun A, Serteser M, Unsal I.
PMID: 26989673
World J Clin Cases. 2016 Mar 16;4(3):81-7. doi: 10.12998/wjcc.v4.i3.81.

A 60-year-old male patient presented with jaundice and dark urine for three days, icteric sclerae and skin rash on his legs for six months. Laboratory investigations revealed an atypical cryoglobulinemia with high hepatitis C virus (HCV)-RNA levels. Imaging studies...

Osteolipoma independent of bone tissue: a case report.

Cases journal

Demiralp B, Alderete JF, Kose O, Ozcan A, Cicek I, Basbozkurt M.
PMID: 19918398
Cases J. 2009 Sep 01;2:8711. doi: 10.4076/1757-1626-2-8711.

INTRODUCTION: Lipomas are the most common benign soft tissue tumors and appear in any part of the body. They typically consist of mature adipose tissue. Osteolipoma is an extremely rare histologic variant of lipoma that contains mature lamellar bone...

rf-SQUID-mediated coherent tunable coupling between a superconducting phase qubit and a lumped-element resonator.

Physical review letters

Allman MS, Altomare F, Whittaker JD, Cicak K, Li D, Sirois A, Strong J, Teufel JD, Simmonds RW.
PMID: 20482130
Phys Rev Lett. 2010 Apr 30;104(17):177004. doi: 10.1103/PhysRevLett.104.177004. Epub 2010 Apr 29.

We demonstrate coherent tunable coupling between a superconducting phase qubit and a lumped-element resonator. The coupling strength is mediated by a flux-biased rf SQUID operated in the nonhysteretic regime. By tuning the applied flux bias to the rf SQUID...

Pyruvate catabolism and hydrogen synthesis pathway genes of Clostridium thermocellum ATCC 27405.

Indian journal of microbiology

Carere CR, Kalia V, Sparling R, Cicek N, Levin DB.
PMID: 23100718
Indian J Microbiol. 2008 Jun;48(2):252-66. doi: 10.1007/s12088-008-0036-z. Epub 2008 Jul 27.

Clostridium thermocellum is a gram-positive, acetogenic, thermophilic, anaerobic bacterium that degrades cellulose and carries out mixed product fermentation, catabolising cellulose to acetate, lactate, and ethanol under various growth conditions, with the concomitant release of H(2) and CO(2). Very little...

Fentanyl transmucosal tablets: current status in the management of cancer-related breakthrough pain.

Patient preference and adherence

Prommer E, Ficek B.
PMID: 22791984
Patient Prefer Adherence. 2012;6:465-75. doi: 10.2147/PPA.S20655. Epub 2012 Jun 25.

Breakthrough pain is a newly recognized pain category that was first described by Portenoy and Hagen in 1990. The term describes pain that increases in intensity to "break through" chronic pain that is being controlled by a scheduled opioid...

Showing 1 to 12 of 211 entries