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Showing 1 to 12 of 16 entries
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Evidence supporting a 1,2-dioxetanone as an intermediate in the benzofuran-2(3H)-one chemiluminescence.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

Ciscato LF, Bartoloni FH, Colavite AS, Weiss D, Beckert R, Schramm S.
PMID: 24162255
Photochem Photobiol Sci. 2014 Jan;13(1):32-7. doi: 10.1039/c3pp50345c. Epub 2013 Oct 28.

The mechanism of the chemiluminescent reaction of ethyl (5-fluoro-2-oxo-2,3-dihydrobenzofuran-3-yl) carbamate (a 2-coumaranone derivative) with a base and molecular oxygen was investigated. New evidence from the reaction kinetics and absorption/emission profiles was obtained, supporting the existence of a 1,2-dioxetanone as...

Metabolic Plasticity of Tumor Cell Mitochondria.

Frontiers in oncology

Cannino G, Ciscato F, Masgras I, Sánchez-Martín C, Rasola A.
PMID: 30197878
Front Oncol. 2018 Aug 24;8:333. doi: 10.3389/fonc.2018.00333. eCollection 2018.

Mitochondria are dynamic organelles that exchange a multiplicity of signals with other cell compartments, in order to finely adjust key biological routines to the fluctuating metabolic needs of the cell. During neoplastic transformation, cells must provide an adequate supply...

Surveillance of neo-squamous epithelium after ablation of Barrett's esophagus: is it better to use jumbo over standard biopsy forceps?.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

Duvvuri A, Desai M, Srinivasan S, Chandrashekar VT, Vennelaganti S, Vennalaganti P, Jani B, Lim D, Ciscato C, Spaggiari P, Consolo P, Porter J, Ferrara E, Kennedy K, Gupta N, Mathur S, Sharma P, Repici A.
PMID: 32462180
Dis Esophagus. 2020 May 28; doi: 10.1093/dote/doaa044. Epub 2020 May 28.

BACKGROUND AND AIMS: As obtaining adequate tissue on biopsy is critical for the detection of residual and recurrent intestinal metaplasia/dysplasia in Barrett's esophagus (BE) patients undergone Barrett's endoscopic eradication therapy (BET), we decided to compare the adequacy of biopsy...

Analysis of the Effects of Hexokinase 2 Detachment From Mitochondria-Associated Membranes with the Highly Selective Peptide HK2pep.

Bio-protocol

Ciscato F, Chiara F, Filadi R, Rasola A.
PMID: 34395726
Bio Protoc. 2021 Jul 20;11(14):e4087. doi: 10.21769/BioProtoc.4087. eCollection 2021 Jul 20.

The crucial role of hexokinase 2 (HK2) in the metabolic rewiring of tumors is now well established, which makes it a suitable target for the design of novel therapies. However, hexokinase activity is central to glucose utilization in all...

Resolution of Cyclicity After Pasireotide LAR in a Patient With Cushing Disease.

AACE clinical case reports

Machado MC, Cescato VAS, Fragoso MCBV, Bronstein MD.
PMID: 34307853
AACE Clin Case Rep. 2021 Mar 09;7(4):277-281. doi: 10.1016/j.aace.2021.02.007. eCollection 2021.

OBJECTIVE: The cyclicity (CIC) of cortisol spontaneously occurs in a minority of patients with Cushing syndrome (CS). When it arises, diagnostic and therapeutic approaches become more challenging. This study aimed to report a patient with Cushing disease (CD) who...

Cushing disease due to a somatic .

Archives of endocrinology and metabolism

Labello JH, Benedetti AFF, Azevedo BV, de Lima Jorge AA, Cescato VAS, Rosemberg S, Frasseto FP, Arnhold IJP, de Carvalho LRS.
PMID: 35029852
Arch Endocrinol Metab. 2022 Jan 13; doi: 10.20945/2359-3997000000428. Epub 2022 Jan 13.

We present the unique case of an adult Brazilian woman with severe short stature due to growth hormone deficiency with a heterozygous G to T substitution in the donor splice site of intron 3 of the growth hormone 1...

Revision of singlet quantum yields in the catalyzed decomposition of cyclic peroxides.

The Journal of organic chemistry

Almeida de Oliveira M, Bartoloni FH, Augusto FA, Ciscato LF, Bastos EL, Baader WJ.
PMID: 22852861
J Org Chem. 2012 Dec 07;77(23):10537-44. doi: 10.1021/jo301309v. Epub 2012 Aug 10.

The chemiluminescence of cyclic peroxides activated by oxidizable fluorescent dyes is an example of chemically initiated electron exchange luminescence (CIEEL), which has been used also to explain the efficient bioluminescence of fireflies. Diphenoyl peroxide and dimethyl-1,2-dioxetanone were used as...

Solvent viscosity influence on the chemiexcitation efficiency of inter and intramolecular chemiluminescence systems.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

Khalid M, Souza SP, Ciscato LF, Bartoloni FH, Baader WJ.
PMID: 26067192
Photochem Photobiol Sci. 2015 Jul;14(7):1296-305. doi: 10.1039/c5pp00152h.

The effects of the medium viscosity on the chemiexcitation quantum yields of the induced decomposition of 1,2-dioxetanes (highly efficient intramolecular CIEEL system) and the catalyzed decomposition of diphenoyl peroxide and a 1,2-dioxetanone derivative (model systems for the intermolecular CIEEL...

Direct kinetic observation of the chemiexcitation step in peroxyoxalate chemiluminescence.

The Journal of organic chemistry

Ciscato LF, Bartoloni FH, Bastos EL, Baader WJ.
PMID: 19711973
J Org Chem. 2009 Dec 04;74(23):8974-9. doi: 10.1021/jo901402k.

A high-energy intermediate in the peroxyoxalate reaction can be accumulated at room temperature under specific reaction conditions and in the absence of any reducing agent in up to micromolar concentrations. Bimolecular interaction of this intermediate, accumulated in the reaction...

Thickened Pituitary Stalk Associated with a Mass in the Sphenoidal Sinus: An Alarm to Suspect Hypophysitis by Immunoglobulin G4?.

International archives of otorhinolaryngology

Batista RL, Ramos LS, Cescato VA, Musolino NR, Borba CG, Silva GO, Moreno LH, Cunha Neto MB.
PMID: 26157505
Int Arch Otorhinolaryngol. 2015 Jul;19(3):273-6. doi: 10.1055/s-0034-1397333. Epub 2015 Mar 05.

Introduction Hypophysitis is a chronic inflammation of the pituitary gland of complex and still incompletely defined pathogenesis. It belongs to the group of non-hormone-secreting sellar masses, sharing with them comparable clinical presentation and radiographic appearance. Objectives Describe the case...

Stormorken Syndrome Caused by a p.R304W .

Frontiers in neurology

Borsani O, Piga D, Costa S, Govoni A, Magri F, Artoni A, Cinnante CM, Fagiolari G, Ciscato P, Moggio M, Bresolin N, Comi GP, Corti S.
PMID: 30374325
Front Neurol. 2018 Oct 15;9:859. doi: 10.3389/fneur.2018.00859. eCollection 2018.

Stormorken syndrome is a rare autosomal dominant disease that is characterized by a complex phenotype that includes tubular aggregate myopathy (TAM), bleeding diathesis, hyposplenism, mild hypocalcemia and additional features, such as miosis and a mild intellectual disability (dyslexia). Stormorken...

First Evidence of In Vitro Effects of C6O4-A Substitute of PFOA-On Haemocytes of the Clam .

Toxics

Fabrello J, Targhetta F, Ciscato M, Asnicar D, Bernardini I, Milan M, Patarnello T, Marin MG, Matozzo V.
PMID: 34437509
Toxics. 2021 Aug 19;9(8). doi: 10.3390/toxics9080191.

Alternative chemicals to per- and poly-fluoroalkyl substances have recently been introduced in various industrial processes. C6O4 (difluoro{[2,2,4,5-tetrafluoro-5-(trifluoromethoxy)-1,3-dioxolan-4-yl]oxy}acetic acid) is a new surfactant and emulsifier used as a replacement for perfluorooctanoic acid (PFOA). From an ecotoxicological point of view, in...

Showing 1 to 12 of 16 entries