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Showing 1 to 12 of 16 entries
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e-Health standardization in Europe: lessons learned.

Studies in health technology and informatics

De Moor GJ, Claerhout B, van Maele G, Dupont D.
PMID: 15718584
Stud Health Technol Inform. 2004;100:233-7.

Challenges regarding standardization in e-Health are analyzed, and solutions for ensuring their practical implementation are proposed. Emphasis is put on new mechanisms for enhancing the collaboration between the industry and standardization bodies.

CSYseq: The first Y-chromosome sequencing tool typing a large number of Y-SNPs and Y-STRs to unravel worldwide human population genetics.

PLoS genetics

Claerhout S, Verstraete P, Warnez L, Vanpaemel S, Larmuseau M, Decorte R.
PMID: 34491993
PLoS Genet. 2021 Sep 07;17(9):e1009758. doi: 10.1371/journal.pgen.1009758. eCollection 2021 Sep.

Male-specific Y-chromosome (chrY) polymorphisms are interesting components of the DNA for population genetics. While single nucleotide polymorphisms (Y-SNPs) indicate distant evolutionary ancestry, short tandem repeats (Y-STRs) are able to identify close familial kinships. Detailed chrY analysis provides thus both...

Next generation sequencing in therapy-related myeloid neoplasms compared to .

Acta clinica Belgica

Claerhout H, Vranckx H, Lierman E, Michaux L, Boeckx N.
PMID: 34197279
Acta Clin Belg. 2021 Jul 01;1-6. doi: 10.1080/17843286.2021.1943232. Epub 2021 Jul 01.

INTRODUCTION: Therapy-related myeloid neoplasms (t-MN) are frequently categorized according to previous therapy or pattern of cytogenetic abnormalities. Our objective was to evaluate and compare the mutational profile of METHODS: Sixty-four samples from patients with t-MN, previously treated for a...

YMrCA: Improving Y-chromosomal ancestor time estimation for DNA kinship research.

Human mutation

Claerhout S, Vanpaemel S, Gill MS, Antiga LG, Baele G, Decorte R.
PMID: 34265144
Hum Mutat. 2021 Oct;42(10):1307-1320. doi: 10.1002/humu.24259. Epub 2021 Jul 29.

The Y-chromosome is a valuable kinship indicator in family history and forensic research. To reconstruct genealogies, the time to the most recent common ancestor (tMRCA) between paternal relatives can be estimated through Y-STR analysis. Existing models are the stepwise...

Malignant invasion of the cerebrospinal fluid in adult and paediatric patients with haematological and solid malignancies: a monocentric retrospective study.

Acta clinica Belgica

Smets L, Claerhout H, Van Laer C, Boeckx N.
PMID: 33729099
Acta Clin Belg. 2021 Mar 17;1-9. doi: 10.1080/17843286.2021.1900493. Epub 2021 Mar 17.

OBJECTIVES: In this study, we describe the clinical presentation, the cerebrospinal fluid (CSF) characteristics and outcome of children and adults with leptomeningeal invasion due to haematological and solid malignancies.METHODS: Routine CSF samples analyzed from 2008 to 2018 at our...

MODULATION OF AUTOPHAGY AND ITS POTENTIAL FOR CANCER THERAPY.

Drugs of the future

Claerhout S, Lorenzi PL, Weinstein JN, Mills GB.
PMID: 25419038
Drugs Future. 2011;36(12). doi: 10.1358/dof.2011.036.12.1711892.

Autophagy is a process in which cellular contents are captured in specialized, membrane-bounded vesicles and delivered to lysosomes for final degradation. Most studies support an inherent connection between autophagy and survival, but increasing evidence also suggests an association between...

ICD-10-CM extension with ICD-9 diagnosis codes to support integrated access to clinical legacy data.

International journal of medical informatics

Hernandez-Ibarburu G, Perez-Rey D, Alonso-Oset E, Alonso-Calvo R, de Schepper K, Meloni L, Claerhout B.
PMID: 31445254
Int J Med Inform. 2019 Sep;129:189-197. doi: 10.1016/j.ijmedinf.2019.06.010. Epub 2019 Jun 17.

INTRODUCTION: ICD is currently the most widely used terminology to code diagnosis and procedures. The transition from ICD-9-CM to ICD-10-CM became effective on October 1, 2015 in US and many other countries. Projects that use this codification for research...

Copper(II)-mediated cross-coupling of arylboronic acids and 2(1H)-pyrazinones facilitated by microwave irradiation with simultaneous cooling.

Organic letters

Singh BK, Appukkuttan P, Claerhout S, Parmar VS, Van der Eycken E.
PMID: 16623570
Org Lett. 2006 Apr 27;8(9):1863-6. doi: 10.1021/ol060422z.

[reaction: see text] Optimized conditions for the decoration of the 2(1H)-pyrazinone scaffold were developed by applying the Chan-Lam protocol. It was demonstrated that this Cu(II)-mediated cross-coupling reaction resulted in significantly improved yields and rates when performed under microwave irradiation...

Characterization of Methyl Transferase Activity in the Mandibular Organ of the American Lobster, Homarus americanus.

The Biological bulletin

Claerhout T, Bendena W, Tobe SS, Borst DW.
PMID: 29220231
Biol Bull. 1996 Oct;191(2):304. doi: 10.1086/BBLv191n2p304.

No abstract available.

A randomized controlled trial of misoprostol and sulprostone to end pregnancy after fetal death.

Obstetrics and gynecology international

Van Mensel K, Claerhout F, Debois P, Keirse MJ, Hanssens M.
PMID: 19960062
Obstet Gynecol Int. 2009;2009:496320. doi: 10.1155/2009/496320. Epub 2009 Sep 06.

Objective. To compare effectiveness, side effects, and patients' perception of vaginal misoprostol versus intravenous sulprostone for ending pregnancy after fetal death between 14 and 42 weeks gestation. Method. Multicenter randomized controlled trial, using block randomization, central allocation, and prior...

Laparoscopic sacrocolpopexy.

Facts, views & vision in ObGyn

Manodoro S, Werbrouck E, Veldman J, Haest K, Corona R, Claerhout F, Coremans G, De Ridder D, Spelzini F, Deprest J.
PMID: 24753860
Facts Views Vis Obgyn. 2011;3(3):151-8.

Laparoscopy offers great exposure and surgical detail, reduces blood loss and the need for excessive abdominal packing-- and bowel manipulation making it an excellent modality to perform pelvic floor surgery. Laparoscopic repair of level I or apical vaginal prolapse...

Mapping clinical procedures to the ICD-10-PCS: The German operation and procedure classification system use case.

Journal of biomedical informatics

Millan-Fernandez-Montes A, Perez-Rey D, Hernandez-Ibarburu G, Palchuk MB, Mueller C, Claerhout B.
PMID: 32717327
J Biomed Inform. 2020 Sep;109:103519. doi: 10.1016/j.jbi.2020.103519. Epub 2020 Jul 25.

Mappings among terminologies to ensure homogeneous analysis among different data sources is one of the key challenges of semantic interoperability. Concretely, mappings to the International Classification of Diseases 10th Revision Procedure Classification System (ICD-10-PCS) are especially challenging due to...

Showing 1 to 12 of 16 entries