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Cometary science. Subsurface properties and early activity of comet 67P/Churyumov-Gerasimenko.

Science (New York, N.Y.)

Gulkis S, Allen M, von Allmen P, Beaudin G, Biver N, Bockelée-Morvan D, Choukroun M, Crovisier J, Davidsson BJ, Encrenaz P, Encrenaz T, Frerking M, Hartogh P, Hofstadter M, Ip WH, Janssen M, Jarchow C, Keihm S, Lee S, Lellouch E, Leyrat C, Rezac L, Schloerb FP, Spilker T.
PMID: 25613896
Science. 2015 Jan 23;347(6220):aaa0709. doi: 10.1126/science.aaa0709.

Heat transport and ice sublimation in comets are interrelated processes reflecting properties acquired at the time of formation and during subsequent evolution. The Microwave Instrument on the Rosetta Orbiter (MIRO) acquired maps of the subsurface temperature of comet 67P/Churyumov-Gerasimenko,...

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Gulkis S, Allen M, von Allmen P, et al. Cometary science. Subsurface properties and early activity of comet 67P/Churyumov-Gerasimenko. Science. 2015;347(6220):aaa0709doi: 10.1126/science.aaa0709.
Gulkis, S., Allen, M., von Allmen, P., Beaudin, G., Biver, N., Bockelée-Morvan, D., Choukroun, M., Crovisier, J., Davidsson, B. J., Encrenaz, P., Encrenaz, T., Frerking, M., Hartogh, P., Hofstadter, M., Ip, W. H., Janssen, M., Jarchow, C., Keihm, S., Lee, S., Lellouch, E., Leyrat, C., Rezac, L., Schloerb, F. P., & Spilker, T. (2015). Cometary science. Subsurface properties and early activity of comet 67P/Churyumov-Gerasimenko. Science (New York, N.Y.), 347(6220), aaa0709. https://doi.org/10.1126/science.aaa0709
Gulkis, Samuel, et al. "Cometary science. Subsurface properties and early activity of comet 67P/Churyumov-Gerasimenko." Science (New York, N.Y.) vol. 347,6220 (2015): aaa0709. doi: https://doi.org/10.1126/science.aaa0709
Gulkis S, Allen M, von Allmen P, Beaudin G, Biver N, Bockelée-Morvan D, Choukroun M, Crovisier J, Davidsson BJ, Encrenaz P, Encrenaz T, Frerking M, Hartogh P, Hofstadter M, Ip WH, Janssen M, Jarchow C, Keihm S, Lee S, Lellouch E, Leyrat C, Rezac L, Schloerb FP, Spilker T. Cometary science. Subsurface properties and early activity of comet 67P/Churyumov-Gerasimenko. Science. 2015 Jan 23;347(6220):aaa0709. doi: 10.1126/science.aaa0709. PMID: 25613896.
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G-computation and doubly robust standardisation for continuous-time data: A comparison with inverse probability weighting.

Statistical methods in medical research

Chatton A, Borgne FL, Leyrat C, Foucher Y.
PMID: 34861799
Stat Methods Med Res. 2021 Dec 03;9622802211047345. doi: 10.1177/09622802211047345. Epub 2021 Dec 03.

In time-to-event settings, g-computation and doubly robust estimators are based on discrete-time data. However, many biological processes are evolving continuously over time. In this paper, we extend the g-computation and the doubly robust standardisation procedures to a continuous-time context....

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Chatton A, Borgne FL, Leyrat C, et al. G-computation and doubly robust standardisation for continuous-time data: A comparison with inverse probability weighting. Stat Methods Med Res. 2021;9622802211047345doi: 10.1177/09622802211047345.
Chatton, A., Borgne, F. L., Leyrat, C., & Foucher, Y. (2021). G-computation and doubly robust standardisation for continuous-time data: A comparison with inverse probability weighting. Statistical methods in medical research, 9622802211047345. https://doi.org/10.1177/09622802211047345
Chatton, Arthur, et al. "G-computation and doubly robust standardisation for continuous-time data: A comparison with inverse probability weighting." Statistical methods in medical research vol. (2021): 9622802211047345. doi: https://doi.org/10.1177/09622802211047345
Chatton A, Borgne FL, Leyrat C, Foucher Y. G-computation and doubly robust standardisation for continuous-time data: A comparison with inverse probability weighting. Stat Methods Med Res. 2021 Dec 03;9622802211047345. doi: 10.1177/09622802211047345. Epub 2021 Dec 03. PMID: 34861799.
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Re: Subramanian and Kumar. Vaccination rates and COVID-19 cases.

European journal of epidemiology

Mulot M, Segalas C, Leyrat C, Besançon L.
PMID: 34951674
Eur J Epidemiol. 2021 Dec 24; doi: 10.1007/s10654-021-00817-6. Epub 2021 Dec 24.

No abstract available.

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Mulot M, Segalas C, Leyrat C, et al. Re: Subramanian and Kumar. Vaccination rates and COVID-19 cases. Eur J Epidemiol. 2021;doi: 10.1007/s10654-021-00817-6.
Mulot, M., Segalas, C., Leyrat, C., & Besançon, L. (2021). Re: Subramanian and Kumar. Vaccination rates and COVID-19 cases. European journal of epidemiology, . https://doi.org/10.1007/s10654-021-00817-6
Mulot, Matthieu, et al. "Re: Subramanian and Kumar. Vaccination rates and COVID-19 cases." European journal of epidemiology vol. (2021). doi: https://doi.org/10.1007/s10654-021-00817-6
Mulot M, Segalas C, Leyrat C, Besançon L. Re: Subramanian and Kumar. Vaccination rates and COVID-19 cases. Eur J Epidemiol. 2021 Dec 24; doi: 10.1007/s10654-021-00817-6. Epub 2021 Dec 24. PMID: 34951674.
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Is there an association between long-term antibiotics for acne and subsequent infection sequelae and antimicrobial resistance? A systematic review.

BJGP open

Bhate K, Lin LY, Barbieri JS, Leyrat C, Hopkins S, Stabler R, Shallcross L, Smeeth L, Francis N, Mathur R, Langan SM, Sinnott SJ.
PMID: 33687983
BJGP Open. 2021 Jun 30;5(3). doi: 10.3399/BJGPO.2020.0181. Print 2021 Jun.

BACKGROUND: Antimicrobial resistance (AMR) is a global health priority. Acne vulgaris is a common skin condition for which antibiotic use ranges from a few months to years of daily exposure.AIM: To systemically search for and synthesise evidence on the...

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Bhate K, Lin LY, Barbieri JS, et al. Is there an association between long-term antibiotics for acne and subsequent infection sequelae and antimicrobial resistance? A systematic review. BJGP Open. 2021;5(3)doi: 10.3399/BJGPO.2020.0181.
Bhate, K., Lin, L. Y., Barbieri, J. S., Leyrat, C., Hopkins, S., Stabler, R., Shallcross, L., Smeeth, L., Francis, N., Mathur, R., Langan, S. M., & Sinnott, S. J. (2021). Is there an association between long-term antibiotics for acne and subsequent infection sequelae and antimicrobial resistance? A systematic review. BJGP open, 5(3), . https://doi.org/10.3399/BJGPO.2020.0181
Bhate, Ketaki, et al. "Is there an association between long-term antibiotics for acne and subsequent infection sequelae and antimicrobial resistance? A systematic review." BJGP open vol. 5,3 (2021). doi: https://doi.org/10.3399/BJGPO.2020.0181
Bhate K, Lin LY, Barbieri JS, Leyrat C, Hopkins S, Stabler R, Shallcross L, Smeeth L, Francis N, Mathur R, Langan SM, Sinnott SJ. Is there an association between long-term antibiotics for acne and subsequent infection sequelae and antimicrobial resistance? A systematic review. BJGP Open. 2021 Jun 30;5(3). doi: 10.3399/BJGPO.2020.0181. Print 2021 Jun. PMID: 33687983; PMCID: PMC8278499.
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Projecting the impact of triple CFTR modulator therapy on intravenous antibiotic requirements in cystic fibrosis using patient registry data combined with treatment effects from randomised trials.

Thorax

Keogh RH, Cosgriff R, Andrinopoulou ER, Brownlee KG, Carr SB, Diaz-Ordaz K, Granger E, Jewell NP, Lewin A, Leyrat C, Schlüter DK, van Smeden M, Szczesniak RD, Connett GJ.
PMID: 34556554
Thorax. 2021 Sep 23; doi: 10.1136/thoraxjnl-2020-216265. Epub 2021 Sep 23.

BACKGROUND: Cystic fibrosis (CF) is a life-threatening genetic disease, affecting around 10 500 people in the UK. Precision medicines have been developed to treat specific CF-gene mutations. The newest, elexacaftor/tezacaftor/ivacaftor (ELEX/TEZ/IVA), has been found to be highly effective in...

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Keogh RH, Cosgriff R, Andrinopoulou ER, et al. Projecting the impact of triple CFTR modulator therapy on intravenous antibiotic requirements in cystic fibrosis using patient registry data combined with treatment effects from randomised trials. Thorax. 2021;doi: 10.1136/thoraxjnl-2020-216265.
Keogh, R. H., Cosgriff, R., Andrinopoulou, E. R., Brownlee, K. G., Carr, S. B., Diaz-Ordaz, K., Granger, E., Jewell, N. P., Lewin, A., Leyrat, C., Schlüter, D. K., van Smeden, M., Szczesniak, R. D., & Connett, G. J. (2021). Projecting the impact of triple CFTR modulator therapy on intravenous antibiotic requirements in cystic fibrosis using patient registry data combined with treatment effects from randomised trials. Thorax, . https://doi.org/10.1136/thoraxjnl-2020-216265
Keogh, Ruth H, et al. "Projecting the impact of triple CFTR modulator therapy on intravenous antibiotic requirements in cystic fibrosis using patient registry data combined with treatment effects from randomised trials." Thorax vol. (2021). doi: https://doi.org/10.1136/thoraxjnl-2020-216265
Keogh RH, Cosgriff R, Andrinopoulou ER, Brownlee KG, Carr SB, Diaz-Ordaz K, Granger E, Jewell NP, Lewin A, Leyrat C, Schlüter DK, van Smeden M, Szczesniak RD, Connett GJ. Projecting the impact of triple CFTR modulator therapy on intravenous antibiotic requirements in cystic fibrosis using patient registry data combined with treatment effects from randomised trials. Thorax. 2021 Sep 23; doi: 10.1136/thoraxjnl-2020-216265. Epub 2021 Sep 23. PMID: 34556554.
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Three dimensional time-gated tracking of non-blinking quantum dots in live cells.

Proceedings of SPIE--the International Society for Optical Engineering

DeVore MS, Stich DG, Keller AM, Ghosh Y, Goodwin PM, Phipps ME, Stewart MH, Cleyrat C, Wilson BS, Lidke DS, Hollingsworth JA, Werner JH.
PMID: 25932286
Proc SPIE Int Soc Opt Eng. 2015 Mar 12;9338. doi: 10.1117/12.2082943.

Single particle tracking has provided a wealth of information about biophysical processes such as motor protein transport and diffusion in cell membranes. However, motion out of the plane of the microscope or blinking of the fluorescent probe used as...

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DeVore MS, Stich DG, Keller AM, et al. Three dimensional time-gated tracking of non-blinking quantum dots in live cells. Proc SPIE Int Soc Opt Eng. 2015;9338doi: 10.1117/12.2082943.
DeVore, M. S., Stich, D. G., Keller, A. M., Ghosh, Y., Goodwin, P. M., Phipps, M. E., Stewart, M. H., Cleyrat, C., Wilson, B. S., Lidke, D. S., Hollingsworth, J. A., & Werner, J. H. (2015). Three dimensional time-gated tracking of non-blinking quantum dots in live cells. Proceedings of SPIE--the International Society for Optical Engineering, 9338. https://doi.org/10.1117/12.2082943
DeVore, Matthew S, et al. "Three dimensional time-gated tracking of non-blinking quantum dots in live cells." Proceedings of SPIE--the International Society for Optical Engineering vol. 9338 (2015). doi: https://doi.org/10.1117/12.2082943
DeVore MS, Stich DG, Keller AM, Ghosh Y, Goodwin PM, Phipps ME, Stewart MH, Cleyrat C, Wilson BS, Lidke DS, Hollingsworth JA, Werner JH. Three dimensional time-gated tracking of non-blinking quantum dots in live cells. Proc SPIE Int Soc Opt Eng. 2015 Mar 12;9338. doi: 10.1117/12.2082943. PMID: 25932286; PMCID: PMC4412170.
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Introduction to computational causal inference using reproducible Stata, R, and Python code: A tutorial.

Statistics in medicine

Smith MJ, Mansournia MA, Maringe C, Zivich PN, Cole SR, Leyrat C, Belot A, Rachet B, Luque-Fernandez MA.
PMID: 34713468
Stat Med. 2022 Jan 30;41(2):407-432. doi: 10.1002/sim.9234. Epub 2021 Oct 28.

The main purpose of many medical studies is to estimate the effects of a treatment or exposure on an outcome. However, it is not always possible to randomize the study participants to a particular treatment, therefore observational study designs...

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Smith MJ, Mansournia MA, Maringe C, et al. Introduction to computational causal inference using reproducible Stata, R, and Python code: A tutorial. Stat Med. 2021;41(2):407-432doi: 10.1002/sim.9234.
Smith, M. J., Mansournia, M. A., Maringe, C., Zivich, P. N., Cole, S. R., Leyrat, C., Belot, A., Rachet, B., & Luque-Fernandez, M. A. (2022). Introduction to computational causal inference using reproducible Stata, R, and Python code: A tutorial. Statistics in medicine, 41(2), 407-432. https://doi.org/10.1002/sim.9234
Smith, Matthew J, et al. "Introduction to computational causal inference using reproducible Stata, R, and Python code: A tutorial." Statistics in medicine vol. 41,2 (2022): 407-432. doi: https://doi.org/10.1002/sim.9234
Smith MJ, Mansournia MA, Maringe C, Zivich PN, Cole SR, Leyrat C, Belot A, Rachet B, Luque-Fernandez MA. Introduction to computational causal inference using reproducible Stata, R, and Python code: A tutorial. Stat Med. 2022 Jan 30;41(2):407-432. doi: 10.1002/sim.9234. Epub 2021 Oct 28. PMID: 34713468.
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Comparative evaluation of the impact of the COVID-19 lockdown on perinatal experience: a prospective multicentre study.

BJOG : an international journal of obstetrics and gynaecology

Bertholdt C, Epstein J, Alleyrat C, Ambroise G, Claudel L, Banasiak C, Morel O.
PMID: 34954895
BJOG. 2021 Dec 26; doi: 10.1111/1471-0528.17082. Epub 2021 Dec 26.

OBJECTIVES: To compare in the early postpartum the perinatal experience during a COVID-19 related lockdown ("lockdown" group) and a pandemic control group subject to looser restrictions.DESIGN & SETTING: This national multicentre prospective cohort study took place in four French...

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Bertholdt C, Epstein J, Alleyrat C, et al. Comparative evaluation of the impact of the COVID-19 lockdown on perinatal experience: a prospective multicentre study. BJOG. 2021;doi: 10.1111/1471-0528.17082.
Bertholdt, C., Epstein, J., Alleyrat, C., Ambroise, G., Claudel, L., Banasiak, C., & Morel, O. (2021). Comparative evaluation of the impact of the COVID-19 lockdown on perinatal experience: a prospective multicentre study. BJOG : an international journal of obstetrics and gynaecology, . https://doi.org/10.1111/1471-0528.17082
Bertholdt, C, et al. "Comparative evaluation of the impact of the COVID-19 lockdown on perinatal experience: a prospective multicentre study." BJOG : an international journal of obstetrics and gynaecology vol. (2021). doi: https://doi.org/10.1111/1471-0528.17082
Bertholdt C, Epstein J, Alleyrat C, Ambroise G, Claudel L, Banasiak C, Morel O. Comparative evaluation of the impact of the COVID-19 lockdown on perinatal experience: a prospective multicentre study. BJOG. 2021 Dec 26; doi: 10.1111/1471-0528.17082. Epub 2021 Dec 26. PMID: 34954895.
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Myocardial blood flows and reserves on solid state camera: Correlations with coronary history and cardiovascular risk factors.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Ferenczi P, Couffinhal T, Mamou A, Mamou Y, Ceyrat Q, Bordenave L, Coste P, Pinaquy JB.
PMID: 34036528
J Nucl Cardiol. 2021 May 25; doi: 10.1007/s12350-021-02659-x. Epub 2021 May 25.

OBJECTIVES: Study designed to test association between stress-induced myocardial blood flow (sMBF), resting MBF (rMBF), and MBF reserve (MFR) and coronary artery disease (CAD) in a population of CAD and non-coronary patients. Secondary objectives were to confront visual analysis...

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Ferenczi P, Couffinhal T, Mamou A, et al. Myocardial blood flows and reserves on solid state camera: Correlations with coronary history and cardiovascular risk factors. J Nucl Cardiol. 2021;doi: 10.1007/s12350-021-02659-x.
Ferenczi, P., Couffinhal, T., Mamou, A., Mamou, Y., Ceyrat, Q., Bordenave, L., Coste, P., & Pinaquy, J. B. (2021). Myocardial blood flows and reserves on solid state camera: Correlations with coronary history and cardiovascular risk factors. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, . https://doi.org/10.1007/s12350-021-02659-x
Ferenczi, Paul, et al. "Myocardial blood flows and reserves on solid state camera: Correlations with coronary history and cardiovascular risk factors." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology vol. (2021). doi: https://doi.org/10.1007/s12350-021-02659-x
Ferenczi P, Couffinhal T, Mamou A, Mamou Y, Ceyrat Q, Bordenave L, Coste P, Pinaquy JB. Myocardial blood flows and reserves on solid state camera: Correlations with coronary history and cardiovascular risk factors. J Nucl Cardiol. 2021 May 25; doi: 10.1007/s12350-021-02659-x. Epub 2021 May 25. PMID: 34036528.
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Open science saves lives: lessons from the COVID-19 pandemic.

BMC medical research methodology

Besançon L, Peiffer-Smadja N, Segalas C, Jiang H, Masuzzo P, Smout C, Billy E, Deforet M, Leyrat C.
PMID: 34090351
BMC Med Res Methodol. 2021 Jun 05;21(1):117. doi: 10.1186/s12874-021-01304-y.

In the last decade Open Science principles have been successfully advocated for and are being slowly adopted in different research communities. In response to the COVID-19 pandemic many publishers and researchers have sped up their adoption of Open Science...

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Besançon L, Peiffer-Smadja N, Segalas C, et al. Open science saves lives: lessons from the COVID-19 pandemic. BMC Med Res Methodol. 2021;21(1):117doi: 10.1186/s12874-021-01304-y.
Besançon, L., Peiffer-Smadja, N., Segalas, C., Jiang, H., Masuzzo, P., Smout, C., Billy, E., Deforet, M., & Leyrat, C. (2021). Open science saves lives: lessons from the COVID-19 pandemic. BMC medical research methodology, 21(1), 117. https://doi.org/10.1186/s12874-021-01304-y
Besançon, Lonni, et al. "Open science saves lives: lessons from the COVID-19 pandemic." BMC medical research methodology vol. 21,1 (2021): 117. doi: https://doi.org/10.1186/s12874-021-01304-y
Besançon L, Peiffer-Smadja N, Segalas C, Jiang H, Masuzzo P, Smout C, Billy E, Deforet M, Leyrat C. Open science saves lives: lessons from the COVID-19 pandemic. BMC Med Res Methodol. 2021 Jun 05;21(1):117. doi: 10.1186/s12874-021-01304-y. PMID: 34090351; PMCID: PMC8179078.
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Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases*.

Angewandte Chemie (International ed. in English)

Healey RD, Saied EM, Cong X, Karsai G, Gabellier L, Saint-Paul J, Del Nero E, Jeannot S, Drapeau M, Fontanel S, Maurel D, Basu S, Leyrat C, Golebiowski J, Bossis G, Bechara C, Hornemann T, Arenz C, Granier S.
PMID: 34668624
Angew Chem Int Ed Engl. 2021 Oct 20; doi: 10.1002/anie.202109967. Epub 2021 Oct 20.

Sphingolipid metabolism is tightly controlled by enzymes to regulate essential processes in human physiology. The central metabolite is ceramide, a pro-apoptotic lipid catabolized by ceramidase enzymes to produce pro-proliferative sphingosine-1-phosphate. Alkaline ceramidases are transmembrane enzymes that recently attracted attention...

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Healey RD, Saied EM, Cong X, et al. Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases*. Angew Chem Int Ed Engl. 2021;doi: 10.1002/anie.202109967.
Healey, R. D., Saied, E. M., Cong, X., Karsai, G., Gabellier, L., Saint-Paul, J., Del Nero, E., Jeannot, S., Drapeau, M., Fontanel, S., Maurel, D., Basu, S., Leyrat, C., Golebiowski, J., Bossis, G., Bechara, C., Hornemann, T., Arenz, C., & Granier, S. (2021). Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases*. Angewandte Chemie (International ed. in English), . https://doi.org/10.1002/anie.202109967
Healey, Robert D, et al. "Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases*." Angewandte Chemie (International ed. in English) vol. (2021). doi: https://doi.org/10.1002/anie.202109967
Healey RD, Saied EM, Cong X, Karsai G, Gabellier L, Saint-Paul J, Del Nero E, Jeannot S, Drapeau M, Fontanel S, Maurel D, Basu S, Leyrat C, Golebiowski J, Bossis G, Bechara C, Hornemann T, Arenz C, Granier S. Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases*. Angew Chem Int Ed Engl. 2021 Oct 20; doi: 10.1002/anie.202109967. Epub 2021 Oct 20. PMID: 34668624.
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Proactive case detection of common childhood illnesses by community health workers: a systematic review.

BMJ global health

Whidden C, Thwing J, Gutman J, Wohl E, Leyrat C, Kayentao K, Johnson AD, Greenwood B, Chandramohan D.
PMID: 31908858
BMJ Glob Health. 2019 Dec 15;4(6):e001799. doi: 10.1136/bmjgh-2019-001799. eCollection 2019.

INTRODUCTION: Identifying design features and implementation strategies to optimise community health worker (CHW) programmes is important in the context of mixed results at scale. We systematically reviewed evidence of the effects of proactive case detection by CHWs in low-income...

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Whidden C, Thwing J, Gutman J, et al. Proactive case detection of common childhood illnesses by community health workers: a systematic review. BMJ Glob Health. 2019;4(6):e001799doi: 10.1136/bmjgh-2019-001799.
Whidden, C., Thwing, J., Gutman, J., Wohl, E., Leyrat, C., Kayentao, K., Johnson, A. D., Greenwood, B., & Chandramohan, D. (2019). Proactive case detection of common childhood illnesses by community health workers: a systematic review. BMJ global health, 4(6), e001799. https://doi.org/10.1136/bmjgh-2019-001799
Whidden, Caroline, et al. "Proactive case detection of common childhood illnesses by community health workers: a systematic review." BMJ global health vol. 4,6 (2019): e001799. doi: https://doi.org/10.1136/bmjgh-2019-001799
Whidden C, Thwing J, Gutman J, Wohl E, Leyrat C, Kayentao K, Johnson AD, Greenwood B, Chandramohan D. Proactive case detection of common childhood illnesses by community health workers: a systematic review. BMJ Glob Health. 2019 Dec 15;4(6):e001799. doi: 10.1136/bmjgh-2019-001799. eCollection 2019. PMID: 31908858; PMCID: PMC6936477.
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