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Showing 1 to 10 of 10 entries
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Reciprocal Induction of MDM2 and MYCN in Neural and Neuroendocrine Cancers.

Frontiers in oncology

Tran HN, Singh HP, Guo W, Cambier L, Riggan L, Shackleford GM, Thornton ME, Grubbs BH, Erdreich-Epstein A, Qi DL, Cobrinik D.
PMID: 33425720
Front Oncol. 2020 Dec 23;10:563156. doi: 10.3389/fonc.2020.563156. eCollection 2020.

MYC family oncoproteins MYC, MYCN, and MYCL are deregulated in diverse cancers and via diverse mechanisms. Recent studies established a novel form of MYCN regulation in MYCN-overexpressing retinoblastoma and neuroblastoma cells in which the MDM2 oncoprotein promotes MYCN translation...

Characterization and staging of outer plexiform layer development in human retina and retinal organoids.

Development (Cambridge, England)

Prameela Bharathan S, Ferrario A, Stepanian K, Fernandez GE, Reid MW, Kim JS, Hutchens C, Harutyunyan N, Marks C, Thornton ME, Grubbs BH, Cobrinik D, Aparicio JG, Nagiel A.
PMID: 34738615
Development. 2021 Dec 01;148(23). doi: 10.1242/dev.199551. Epub 2021 Dec 08.

The development of the first synapse of the visual system between photoreceptors and bipolar cells in the outer plexiform layer (OPL) of the human retina is crucial for visual processing but poorly understood. By studying the maturation state and...

Detection and Intraretinal Localization of an 'Invisible' Retinoblastoma Using Optical Coherence Tomography.

Ocular oncology and pathology

Berry JL, Cobrinik D, Kim JW.
PMID: 27239455
Ocul Oncol Pathol. 2016 Apr;2(3):148-52. doi: 10.1159/000442167. Epub 2015 Nov 27.

PURPOSE: To report the use of handheld spectral-domain optical coherence tomography (HHSD OCT) to identify and define the intraretinal location of a small retinoblastoma that was not detectable by indirect ophthalmoscopy.METHODS: This is a retrospective case report of a...

Characterization and staging of outer plexiform layer development in human retina and retinal organoids.

Development (Cambridge, England)

Prameela Bharathan S, Ferrario A, Stepanian K, Fernandez GE, Reid MW, Kim JS, Hutchens C, Harutyunyan N, Marks C, Thornton ME, Grubbs BH, Cobrinik D, Aparicio JG, Nagiel A.
PMID: 34738615
Development. 2021 Dec 01;148(23). doi: 10.1242/dev.199551. Epub 2021 Dec 08.

The development of the first synapse of the visual system between photoreceptors and bipolar cells in the outer plexiform layer (OPL) of the human retina is crucial for visual processing but poorly understood. By studying the maturation state and...

Characterization and staging of outer plexiform layer development in human retina and retinal organoids.

Development (Cambridge, England)

Prameela Bharathan S, Ferrario A, Stepanian K, Fernandez GE, Reid MW, Kim JS, Hutchens C, Harutyunyan N, Marks C, Thornton ME, Grubbs BH, Cobrinik D, Aparicio JG, Nagiel A.
PMID: 34738615
Development. 2021 Dec 01;148(23). doi: 10.1242/dev.199551. Epub 2021 Dec 08.

The development of the first synapse of the visual system between photoreceptors and bipolar cells in the outer plexiform layer (OPL) of the human retina is crucial for visual processing but poorly understood. By studying the maturation state and...

Corrigendum to "Conservative management of retinoblastoma: Challenging orthodoxy without compromising the state of metastatic grace. "Alive, with good vision and no comorbidity"" [Prog. Retina Eye Res. 73 (2019) 100764].

Progress in retinal and eye research

Munier FL, Beck-Popovic M, Chantada GL, Cobrinik D, Kivelä TT, Lohmann D, Maeder P, Moll AC, Carcaboso AM, Moulin A, Schaiquevich P, Bergin C, Dyson PJ, Houghton S, Puccinelli F, Vial Y, Gaillard MC, Stathopoulos C.
PMID: 32278633
Prog Retin Eye Res. 2020 Apr 08;100857. doi: 10.1016/j.preteyeres.2020.100857. Epub 2020 Apr 08.

No abstract available.

Characterization and staging of outer plexiform layer development in human retina and retinal organoids.

Development (Cambridge, England)

Prameela Bharathan S, Ferrario A, Stepanian K, Fernandez GE, Reid MW, Kim JS, Hutchens C, Harutyunyan N, Marks C, Thornton ME, Grubbs BH, Cobrinik D, Aparicio JG, Nagiel A.
PMID: 34738615
Development. 2021 Dec 01;148(23). doi: 10.1242/dev.199551. Epub 2021 Dec 08.

The development of the first synapse of the visual system between photoreceptors and bipolar cells in the outer plexiform layer (OPL) of the human retina is crucial for visual processing but poorly understood. By studying the maturation state and...

Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma.

Cancers

Kim ME, Polski A, Xu L, Prabakar RK, Peng CC, Reid MW, Shah R, Kuhn P, Cobrinik D, Hicks J, Berry JL.
PMID: 34283049
Cancers (Basel). 2021 Jul 03;13(13). doi: 10.3390/cancers13133340.

Aqueous humor (AH) liquid biopsy has been established as a surrogate tumor biopsy for retinoblastoma (RB). Previous AH studies have focused on highly recurrent RB somatic copy number alterations (SCNAs) including gain of 1q, 2p, 6p, and loss of...

Establishing the Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid Biopsy.

Cancers

Xu L, Kim ME, Polski A, Prabakar RK, Shen L, Peng CC, Reid MW, Chévez-Barrios P, Kim JW, Shah R, Jubran R, Kuhn P, Cobrinik D, Biegel JA, Gai X, Hicks J, Berry JL.
PMID: 33805776
Cancers (Basel). 2021 Mar 13;13(6). doi: 10.3390/cancers13061282.

Because direct tumor biopsy is prohibited for retinoblastoma (RB), eye-specific molecular biomarkers are not used in clinical practice for RB. Recently, we demonstrated that the aqueous humor (AH) is a rich liquid biopsy source of cell-free tumor DNA. Herein,...

Characterization and staging of outer plexiform layer development in human retina and retinal organoids.

Development (Cambridge, England)

Prameela Bharathan S, Ferrario A, Stepanian K, Fernandez GE, Reid MW, Kim JS, Hutchens C, Harutyunyan N, Marks C, Thornton ME, Grubbs BH, Cobrinik D, Aparicio JG, Nagiel A.
PMID: 34738615
Development. 2021 Dec 01;148(23). doi: 10.1242/dev.199551. Epub 2021 Dec 08.

The development of the first synapse of the visual system between photoreceptors and bipolar cells in the outer plexiform layer (OPL) of the human retina is crucial for visual processing but poorly understood. By studying the maturation state and...

Showing 1 to 10 of 10 entries