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Showing 1 to 12 of 34 entries
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14th St. Gallen International Breast Cancer Conference 2015: Evidence, Controversies, Consensus - Primary Therapy of Early Breast Cancer: Opinions Expressed by German Experts.

Breast care (Basel, Switzerland)

Jackisch C, Harbeck N, Huober J, von Minckwitz G, Gerber B, Kreipe HH, Liedtke C, Marschner N, Möbus V, Scheithauer H, Schneeweiss A, Thomssen C, Loibl S, Beckmann MW, Blohmer JU, Costa SD, Decker T, Diel I, Fasching PA, Fehm T, Janni W, Lück HJ, Maass N, Scharl A, Untch M.
PMID: 26557827
Breast Care (Basel). 2015 Jul;10(3):211-9. doi: 10.1159/000433590. Epub 2015 Jun 23.

The key topics of this year's 14th St. Gallen Consensus Conference on the diagnosis and therapy of primary breast cancer were again questions about breast surgery and axillary surgery, radio-oncology and systemic therapy options in consideration of tumor biology,...

Cobalt(III) diazabutadiene precursors for metal deposition: nanoparticle and thin film growth.

Inorganic chemistry

Pugh T, Cosham SD, Hamilton JA, Kingsley AJ, Johnson AL.
PMID: 24236689
Inorg Chem. 2013 Dec 02;52(23):13719-29. doi: 10.1021/ic402317g. Epub 2013 Nov 15.

We report the synthesis and characterization of a family of cobalt(III) metal precursors, based around cyclopentadienyl and diazabutadiene ligands. The molecular structure of the complexes cyclopentadienyl-Cobalt(III)(N,N'-dicyclohexyl-diazabutadiene) (2c) and cyclopentadienyl-Cobalt(III)(N,N'-dimesityl-diazabutadiene) (2d) are described, as determined by single crystal X-ray diffraction...

B cells: the old new players in reproductive immunology.

Frontiers in immunology

Fettke F, Schumacher A, Costa SD, Zenclussen AC.
PMID: 25002862
Front Immunol. 2014 Jun 23;5:285. doi: 10.3389/fimmu.2014.00285. eCollection 2014.

Reproductive immunology research has long focused on T cell responses to paternal antigens and tolerance mechanisms supporting fetal well-being. The participation of B cells herein was not widely studied. Because of the fascinating immunological uniqueness of pregnancy, it is...

Structural tungsten-imido chemistry: the gas-phase structure of W(NBut)2(NHBut)2 and the solid-state structures of novel heterobimetallic W/N/M (M = Rh, Pd, Zn) species.

Inorganic chemistry

Choujaa H, Cosham SD, Johnson AL, Kafka GR, Mahon MF, Masters SL, Molloy KC, Rankin DW, Robertson HE, Wann DA.
PMID: 19166314
Inorg Chem. 2009 Mar 02;48(5):2289-99. doi: 10.1021/ic8021134.

The gas-phase (electron diffraction) and solid-state (X-ray) structures of W(NBut)2(NHBut)2 (1) have been determined. In the gas phase, 1 adopts both C1 and C2 conformations in a 69:31 ratio. The solid-state structure is disordered over two equal sites, both...

Enhanced S100B expression in T and B lymphocytes in spontaneous preterm birth and preeclampsia.

Journal of perinatal medicine

Busse M, Scharm M, Oettel A, Redlich A, Costa SD, Zenclussen AC.
PMID: 34717052
J Perinat Med. 2021 Nov 01; doi: 10.1515/jpm-2021-0326. Epub 2021 Nov 01.

OBJECTIVES: S100B belongs to the family of danger signaling proteins. It is mainly expressed by glial-specific cells in the brain. However, S100B was also detected in other cell likewise immune cells. This molecule was suggested as biomarker for inflammation...

Maternal and Fetal Mechanisms of B Cell Regulation during Pregnancy: Human Chorionic Gonadotropin Stimulates B Cells to Produce IL-10 While Alpha-Fetoprotein Drives Them into Apoptosis.

Frontiers in immunology

Fettke F, Schumacher A, Canellada A, Toledo N, Bekeredjian-Ding I, Bondt A, Wuhrer M, Costa SD, Zenclussen AC.
PMID: 28008329
Front Immunol. 2016 Dec 08;7:495. doi: 10.3389/fimmu.2016.00495. eCollection 2016.

Maternal immune tolerance toward the fetus is an essential requisite for pregnancy. While T cell functions are well documented, little is known about the participation of B cells. We have previously suggested that IL-10-producing B cells are involved in...

Imbalance between inflammatory and regulatory cord blood B cells following pre-term birth.

Journal of reproductive immunology

Busse M, Redlich A, Hartig R, Costa SD, Rathert H, Fest S, Zenclussen AC.
PMID: 33848896
J Reprod Immunol. 2021 Jun;145:103319. doi: 10.1016/j.jri.2021.103319. Epub 2021 Apr 08.

Preterm birth (PTB) is one of the most frequent pregnancy complications. It affects millions of babies each year worldwide and is associated with increased morbidity and mortality. PTB-associated alterations in the maternal immune response may have a direct effect...

Combining single source chemical vapour deposition precursors to explore the phase space of titanium oxynitride thin films.

Dalton transactions (Cambridge, England : 2003)

Rees K, Lorusso E, Cosham SD, Kulak AN, Hyett G.
PMID: 29441374
Dalton Trans. 2018 Aug 07;47(31):10536-10543. doi: 10.1039/c7dt04694d.

In this paper we report on a novel chemical vapour deposition approach to the formation and control of composition of mixed anion materials, as applied to titanium oxynitride thin films. The method used is the aerosol assisted chemical vapour...

Future Roles of Lapatinib in ErbB2-Positive Breast Cancer: Adjuvant and Neoadjuvant Trials.

Breast care (Basel, Switzerland)

Costa SD, Jackisch C, Thomssen C.
PMID: 20847929
Breast Care (Basel). 2010;5:22-24. doi: 10.1159/000285778. Epub 2010 Apr 26.

SUMMARY: Lapatinib is potentially an ideal therapy for the adjuvant and neoadjuvant treatment of women with breast cancer due to its convenience of use (oral, once-daily administration) and because it has shown activity in the first-line and refractory metastatic...

Tailoring precursors for deposition: synthesis, structure, and thermal studies of cyclopentadienylcopper(i) isocyanide complexes.

Inorganic chemistry

Willcocks AM, Pugh T, Cosham SD, Hamilton J, Sung SL, Heil T, Chalker PR, Williams PA, Kociok-Köhn G, Johnson AL.
PMID: 25938738
Inorg Chem. 2015 May 18;54(10):4869-81. doi: 10.1021/acs.inorgchem.5b00448. Epub 2015 May 04.

We report here the synthesis and characterization of a family of copper(I) metal precursors based around cyclopentadienyl and isocyanide ligands. The molecular structures of several cyclopentadienylcopper(I) isocyanide complexes have been unambiguously determined by single-crystal X-ray diffraction analysis. Thermogravimetric analysis...

Primary Therapy of Patients with Early Breast Cancer: Evidence, Controversies, Consensus: Opinions of German Specialists to the 14th St. Gallen International Breast Cancer Conference 2015 (Vienna 2015).

Geburtshilfe und Frauenheilkunde

Untch M, Harbeck N, Huober J, von Minckwitz G, Gerber B, Kreipe HH, Liedtke C, Marschner N, Möbus V, Scheithauer H, Schneeweiss A, Thomssen C, Jackisch C, Beckmann MW, Blohmer JU, Costa SD, Decker T, Diel I, Fasching PA, Fehm T, Janni W, Lück HJ, Maass N, Scharl A, Loibl S.
PMID: 26166836
Geburtshilfe Frauenheilkd. 2015 Jun;75(6):556-565. doi: 10.1055/s-0035-1546120. Epub 2015 Jun 17.

For the first time, this year's St. Gallen International Consensus Conference on the treatment of patients with primary breast cancer, which takes place every two years, was held not in St. Gallen (Switzerland) but - for logistical reasons -...

13th st. Gallen international breast cancer conference 2013: primary therapy of early breast cancer evidence, controversies, consensus - opinion of a german team of experts (zurich 2013).

Breast care (Basel, Switzerland)

Untch M, Gerber B, Harbeck N, Jackisch C, Marschner N, Möbus V, von Minckwitz G, Loibl S, Beckmann MW, Blohmer JU, Costa SD, Decker T, Diel I, Dimpfl T, Eiermann W, Fehm T, Friese K, Jänicke F, Janni W, Jonat W, Kiechle M, Köhler U, Lück HJ, Maass N, Possinger K, Rody A, Scharl A, Schneeweiss A, Thomssen C, Wallwiener D, Welt A.
PMID: 24415975
Breast Care (Basel). 2013 Jun;8(3):221-9. doi: 10.1159/000351692.

The International Consensus Conference on the treatment of primary breast cancer takes place every two years in St. Gallen, Switzerland. The panel in St. Gallen is composed of international experts from different countries. From a German perspective, it seems...

Showing 1 to 12 of 34 entries