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Effects of mitotane treatment on human steroid metabolism: implications for patient management.

Endocrine connections

Ghataore L, Chakraborti I, Aylwin SJ, Schulte KM, Dworakowska D, Coskeran P, Taylor NF.
PMID: 23781302
Endocr Connect. 2012 Jul 21;1(1):37-47. doi: 10.1530/EC-12-0028. Print 2012 Jul 01.

Mitotane (o,p'-DDD), an oral adrenolytic agent for treatment of advanced adrenocortical carcinoma (ACC), is reported to inhibit cortisol biosynthesis in vitro and enhance production from exogenous cortisol of urinary 6β-hydroxycortisol and unidentified polar unconjugated metabolites. We examined urinary steroid...

Cite
Ghataore L, Chakraborti I, Aylwin SJ, et al. Effects of mitotane treatment on human steroid metabolism: implications for patient management. Endocr Connect. 2012;1(1):37-47doi: 10.1530/EC-12-0028.
Ghataore, L., Chakraborti, I., Aylwin, S. J., Schulte, K. M., Dworakowska, D., Coskeran, P., & Taylor, N. F. (2012). Effects of mitotane treatment on human steroid metabolism: implications for patient management. Endocrine connections, 1(1), 37-47. https://doi.org/10.1530/EC-12-0028
Ghataore, L, et al. "Effects of mitotane treatment on human steroid metabolism: implications for patient management." Endocrine connections vol. 1,1 (2012): 37-47. doi: https://doi.org/10.1530/EC-12-0028
Ghataore L, Chakraborti I, Aylwin SJ, Schulte KM, Dworakowska D, Coskeran P, Taylor NF. Effects of mitotane treatment on human steroid metabolism: implications for patient management. Endocr Connect. 2012 Jul 21;1(1):37-47. doi: 10.1530/EC-12-0028. Print 2012 Jul 01. PMID: 23781302; PMCID: PMC3682235.
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