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CYP3A5 is the major cytochrome P450 3A expressed in human colon and colonic cell lines.

Environmental toxicology and pharmacology

Gervot L, Carrière V, Costet P, Cugnenc PH, Berger A, Beaune PH, de Waziers I.
PMID: 21781746
Environ Toxicol Pharmacol. 1996 Dec 20;2(4):381-8. doi: 10.1016/s1382-6689(96)00075-0.

CYP3A is known to be expressed in liver, small intestine and colon. However, its isoform distribution (CYP3A4, 3A5 and 3A7) and inducibility have not been clearly elucidated in the colon. Therefore, we analyzed CYP3A in human colon and compared...

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