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Showing 1 to 12 of 47 entries
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Draft Genome Sequence of Vibrio parahaemolyticus VH3, Isolated from an Aquaculture Environment in Greece.

Genome announcements

Castillo D, Jun JW, D'Alvise P, Middelboe M, Gram L, Liu S, Katharios P.
PMID: 26139725
Genome Announc. 2015 Jul 02;3(4). doi: 10.1128/genomeA.00731-15.

Vibrio parahaemolyticus is an important foodborne pathogen responsible for gastroenteritis outbreaks globally. It has also been identified as an important pathogen in aquatic organisms. Here, we report a draft genome sequence of V. parahaemolyticus, strain VH3, isolated from farmed...

Pediatric Motor Inflammatory Neuropathy: The Role of Antiphospholipid Antibodies.

Brain sciences

Brogna C, Luigetti M, Norcia G, Scalise R, Ferrantini G, Berti B, Romeo DM, Manna R, Mercuri E, Pane M.
PMID: 32156084
Brain Sci. 2020 Mar 07;10(3). doi: 10.3390/brainsci10030156.

We report the clinical case of a nine-year-old girl who presented with progressive motor neuropathy, revealed via the detection of a higher delay in F-wave recording using digitalized nerve conduction/electromyography. Since the lupus anticoagulant (LAC) positivity, detected using diluted...

Maximizing cancer therapy via complementary mechanisms of immune activation: PD-1 blockade, neoantigen vaccination, and Tregs depletion.

Journal for immunotherapy of cancer

D'Alise AM, Leoni G, De Lucia M, Langone F, Nocchi L, Tucci FG, Micarelli E, Cotugno G, Troise F, Garzia I, Vitale R, Bignone V, Di Matteo E, Bartolomeo R, Charych DH, Lahm A, Zalevsky J, Nicosia A, Scarselli E.
PMID: 34824160
J Immunother Cancer. 2021 Nov;9(11). doi: 10.1136/jitc-2021-003480.

BACKGROUND: A number of different immune pathways are involved in the effective killing of cancer cells, collectively named as the 'Cancer Immunity Cycle'. Anti-PD-1 checkpoint blockade (CPB) therapy is active on one of these pathways and reinvigorates anticancer T...

Selective dopaminergic effects on attention and memory in male mice exposed to Methylmercury during adolescence.

Neurotoxicology and teratology

Kendricks DR, Newland MC.
PMID: 34274440
Neurotoxicol Teratol. 2021 Sep-Oct;87:107016. doi: 10.1016/j.ntt.2021.107016. Epub 2021 Jul 16.

Gestational exposure to methylmercury disrupts dopamine-mediated behavior and produces heightened sensitivity to monoamine agonists later in life. This has been reported and replicated following both pre- and post-natal exposure. Impacts of methylmercury when exposure occurs during the sensitive period...

Movement Disorders in Children with a Mitochondrial Disease: A Cross-Sectional Survey from the Nationwide Italian Collaborative Network of Mitochondrial Diseases.

Journal of clinical medicine

Ticci C, Orsucci D, Ardissone A, Bello L, Bertini E, Bonato I, Bruno C, Carelli V, Diodato D, Doccini S, Donati MA, Dosi C, Filosto M, Fiorillo C, La Morgia C, Lamperti C, Marchet S, Martinelli D, Minetti C, Moggio M, Mongini TE, Montano V, Moroni I, Musumeci O, Pancheri E, Pegoraro E, Primiano G, Procopio E, Rubegni A, Scalise R, Sciacco M, Servidei S, Siciliano G, Simoncini C, Tolomeo D, Tonin P, Toscano A, Tubili F, Mancuso M, Battini R, Santorelli FM.
PMID: 34065803
J Clin Med. 2021 May 12;10(10). doi: 10.3390/jcm10102063.

Movement disorders are increasingly being recognized as a manifestation of childhood-onset mitochondrial diseases (MDs). However, the spectrum and characteristics of these conditions have not been studied in detail in the context of a well-defined cohort of patients. We retrospectively...

Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment.

Molecular therapy oncolytics

De Lucia M, Cotugno G, Bignone V, Garzia I, Nocchi L, Langone F, Petrovic B, Sasso E, Pepe S, Froechlich G, Gentile C, Zambrano N, Campadelli-Fiume G, Nicosia A, Scarselli E, D'Alise AM.
PMID: 33209980
Mol Ther Oncolytics. 2020 Oct 14;19:253-264. doi: 10.1016/j.omto.2020.10.006. eCollection 2020 Dec 16.

Oncolytic viruses (OVs) are novel anti-tumor agents with the ability to selectively infect and kill tumor cells while sparing normal tissue. Beyond tumor cytolysis, OVs are capable of priming an anti-tumor immune response via lysis and cross-presentation of locally...

A Retrospective Longitudinal Study in a Cohort of Children With Dyskinetic Cerebral Palsy Treated With Tetrabenazine.

Frontiers in neurology

Scalise R, Sgandurra G, Menici V, Capodagli N, Di Pietro R, Romeo DM, Sini F, Pagliano E, Foscan M, Cioni G, Battini R.
PMID: 33716922
Front Neurol. 2021 Feb 26;12:612429. doi: 10.3389/fneur.2021.612429. eCollection 2021.

Tetrabenazine has been studied with a variety of hyperkinetic movement disorders, but there is limited and empirical literature on the potential efficacy of tetrabenazine in children with dyskinetic cerebral palsy (DCP). The purpose of this study was to evaluate...

How Does Stroke Affect Skeletal Muscle? State of the Art and Rehabilitation Perspective.

Frontiers in neurology

Azzollini V, Dalise S, Chisari C.
PMID: 35002937
Front Neurol. 2021 Dec 23;12:797559. doi: 10.3389/fneur.2021.797559. eCollection 2021.

Long-term disability caused by stroke is largely due to an impairment of motor function. The functional consequences after stroke are caused by central nervous system adaptations and modifications, but also by the peripheral skeletal muscle changes. The nervous and...

How Does Stroke Affect Skeletal Muscle? State of the Art and Rehabilitation Perspective.

Frontiers in neurology

Azzollini V, Dalise S, Chisari C.
PMID: 35002937
Front Neurol. 2021 Dec 23;12:797559. doi: 10.3389/fneur.2021.797559. eCollection 2021.

Long-term disability caused by stroke is largely due to an impairment of motor function. The functional consequences after stroke are caused by central nervous system adaptations and modifications, but also by the peripheral skeletal muscle changes. The nervous and...

Empiric ablation of polymorphic ventricular tachycardia/fibrillation in the absence of a mappable trigger: Prospective feasibility and efficacy of pacemap matching to defibrillator electrograms.

Heart rhythm

Salazar P, Beaser A, Upadhyay G, Aziz Z, Besser S, Shatz DY, Nayak H, Tung R.
PMID: 34757186
Heart Rhythm. 2021 Oct 30; doi: 10.1016/j.hrthm.2021.10.025. Epub 2021 Oct 30.

BACKGROUND: Catheter ablation strategies for ventricular fibrillation (VF) and polymorphic ventricular tachycardia (PMVT) are not established when spontaneous triggers are rare or absent.OBJECTIVE: The purpose of this study was to report the feasibility and efficacy of a novel empiric...

Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells.

Cancers

Passariello M, Vetrei C, Sasso E, Froechlich G, Gentile C, D'Alise AM, Zambrano N, Scarselli E, Nicosia A, De Lorenzo C.
PMID: 32781690
Cancers (Basel). 2020 Aug 06;12(8). doi: 10.3390/cancers12082204.

The cytotoxic T lymphocyte-antigen 4 (CTLA-4) has been considered an IC exclusively expressed on T cells, where it counteracts the co-stimulatory CD28 receptor, by competing for its binding to CD-80 and CD-86. We recently found that it is expressed...

Global occurrence and heterogeneity of the Roseobacter-clade species Ruegeria mobilis.

The ISME journal

Sonnenschein EC, Nielsen KF, D'Alvise P, Porsby CH, Melchiorsen J, Heilmann J, Kalatzis PG, López-Pérez M, Bunk B, Spröer C, Middelboe M, Gram L.
PMID: 28117449
ISME J. 2017 Feb;11(2):588. doi: 10.1038/ismej.2016.125.

No abstract available.

Showing 1 to 12 of 47 entries