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Relationships between the constructs of a theory of curriculum implementation

Science education

Aldous C.
GSID: FOEkQxdna6MJ
J Rogan, C Aldous - Journal of Research in Science Teaching …, 2005 - Wiley Online Library

Planned educational change occurs regularly throughout the world. With the enormous political change the 1994 elections brought to South Africa, a complete change in education …

Understanding the experiences of doctors who undertake elective surgery on HIV/AIDS patients in an area of high incidence in South Africa.

African journal of AIDS research : AJAR

Gwala-Ngozo J, Taylor M, Aldous C.
PMID: 25860408
Afr J AIDS Res. 2010 Apr;9(1):11-6. doi: 10.2989/16085906.2010.484536.

This study investigates the experiences of doctors who perform elective surgical procedures in an area of South Africa with a high incidence of HIV and AIDS. A qualitative study approach was adopted. Interviews were individually conducted with 15 doctors....

Bound electronic and free carrier nonlinearities in Silicon nanocrystals at 1550nm.

Optics express

Spano R, Daldosso N, Cazzanelli M, Ferraioli L, Tartara L, Yu J, Degiorgio V, Giordana E, Fedeli JM, Pavesi L.
PMID: 19259235
Opt Express. 2009 Mar 02;17(5):3941-50. doi: 10.1364/oe.17.003941.

We present a detailed investigation of the different processes responsible for the optical nonlinearities of silicon nanocrystals at 1550 nm. Through z-scan measurements, the bound-electronic and excited carrier contributions to the nonlinear refraction were measured in presence of two-photon...

Optical Study of Diamine Coupling on Carboxyl-Functionalized Mesoporous Silicon.

Journal of nanoscience and nanotechnology

Ghafarinazzari A, Paterlini V, Cortelletti P, Bettotti P, Scarpa M, Daldosso N.
PMID: 29683298
J Nanosci Nanotechnol. 2017 Feb;17(2):1240-246. doi: 10.1166/jnn.2017.12807.

A functionalization strategy, consisting of a silylation reaction by acrylic acid followed by diamine coupling, preserves and stabilizes the photoluminescence (PL) of porous silicon (pSi) microparticles suspended in ethanol. We found that under the condition of efficient amine coupling,...

Donor derived leukemia in allogeneic transplantation.

Leukemia & lymphoma

Aldoss I, Clark M, Marcucci G, Forman SJ.
PMID: 34713775
Leuk Lymphoma. 2021 Dec;62(12):2823-2830. doi: 10.1080/10428194.2021.1929966. Epub 2021 Oct 29.

Allogeneic hematopoietic cell transplantation (alloHCT) is a curative option for the treatment of eligible patients with hematological malignancies. This modality confers a risk for life-threatening complications, including the rare and underdiagnosed complication of donor-derived leukemia (DDL). DDL differs from...

Outcomes of Stevens-Johnson syndrome and toxic epidermal necrolysis in HIV-infected patients when using systemic steroids and/or intravenous immunoglobulins in Pietermaritzburg, South Africa.

Southern African journal of HIV medicine

Chateau AV, Dlova NC, Dawood H, Aldous C.
PMID: 31308970
South Afr J HIV Med. 2019 Jul 04;20(1):944. doi: 10.4102/sajhivmed.v20i1.944. eCollection 2019.

BACKGROUND: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe life-threatening mucocutaneous reactions. There is an ongoing controversy regarding the use of systemic corticosteroids and intravenous immunoglobulin (IVIG) in SJS/TEN and their utility in HIV-infected patients.OBJECTIVES: The objective...

Venetoclax and hypomethylating agents in FLT3-mutated acute myeloid leukemia.

American journal of hematology

Aldoss I, Zhang J, Mei M, Al Malki MM, Arslan S, Ngo D, Aribi A, Ali H, Sandhu K, Salhotra A, Koller P, Khaled S, Artz A, Snyder D, Nakamura R, Forman SJ, Stein AS, Marcucci G, Pullarkat V.
PMID: 32628327
Am J Hematol. 2020 Jul 06; doi: 10.1002/ajh.25929. Epub 2020 Jul 06.

FMS-like tyrosine kinase 3 (FLT3) mutations are prevalent in acute myeloid leukemia (AML), and their presence confers adverse risk. FLT3-mutated (FLT3m) AML is a challenging leukemia to manage, particularly in older and unfit patients as well as patients with...

Venetoclax and hypomethylating agents yield high response rates and favourable transplant outcomes in patients with newly diagnosed acute myeloid leukaemia.

British journal of haematology

Salhotra A, Tsai NC, Zhang J, Ngo D, Aribi A, Sandhu K, Ball B, Al-Malki M, Ali H, Koller P, Artz A, Forman S, Nakamura R, Stein A, Marcucci G, Aldoss I, Pullarkat V.
PMID: 34931310
Br J Haematol. 2021 Dec 21; doi: 10.1111/bjh.17996. Epub 2021 Dec 21.

No abstract available.

Modelled epidemiological data for selected congenital disorders in South Africa.

Journal of community genetics

Malherbe HL, Aldous C, Christianson AL, Darlison MW, Modell B.
PMID: 33674966
J Community Genet. 2021 Jul;12(3):357-376. doi: 10.1007/s12687-021-00513-8. Epub 2021 Mar 05.

Congenital disorders (CD) remain an unprioritized health care issue in South Africa with national surveillance underreporting by > 95%. This lack of empiric data contributes to an underestimation of the CD disease burden, resulting in a lack of services...

Have any strategies in Ph-like ALL been shown to be effective?.

Best practice & research. Clinical haematology

Aldoss I, Advani AS.
PMID: 33762097
Best Pract Res Clin Haematol. 2021 Mar;34(1):101242. doi: 10.1016/j.beha.2021.101242. Epub 2021 Jan 11.

Philadelphia-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk subset of B-cell ALL characterized by high rates of treatment failure. Unsatisfactory outcomes with frontline therapy in adults with Ph-like ALL have been observed irrespective of the employed regimen, including...

Mutations of mtDNA polymerase-γ and hyperlactataemia in the HIV-infected Zulu population of South Africa.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

Ojwach DB, Aldous C, Kochleff P, Sartorius B.
PMID: 27917773
S Afr Med J. 2016 Dec 01;106(12):1254-1259. doi: 10.7196/SAMJ.2016.v106.i12.10818.

BACKGROUND: Mitochondrial toxicity, particularly symptomatic hyperlactataemia or lactic acidosis (SHL/LA), has been attributed to the use of nucleoside reverse transcriptase inhibitors (NRTIs), possibly because of their capacity to impede human mitochondrial DNA polymerase-γ (POLG), which is responsible for the...

Congenital disorders in South Africa: A review of Child Healthcare Problem Identification Programme (Child PIP) mortality data, 2005 - 2017.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

Patrick M, Malherbe H, Stephen C, Woods D, Aldous C.
PMID: 30182880
S Afr Med J. 2018 Jul 25;108(8):647-653. doi: 10.7196/SAMJ.2018.v108i8.12980.

BACKGROUND: Congenital disorders (CDs) form a major challenge for those affected, and for the structuring of services around their health needs. In South Africa (SA) the size and nature of the problem are unknown because reporting of CDs has...

Showing 1 to 12 of 74 entries