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Showing 1 to 12 of 137 entries
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Explanation of low efficiency droop in semipolar (202¯1¯) InGaN/GaN LEDs through evaluation of carrier recombination coefficients.

Optics express

Monavarian M, Rashidi A, Aragon A, Oh SH, Nami M, DenBaars SP, Feezell D.
PMID: 29041128
Opt Express. 2017 Aug 07;25(16):19343-19353. doi: 10.1364/OE.25.019343.

We report the carrier dynamics and recombination coefficients in single-quantum-well semipolar (202¯1¯) InGaN/GaN light-emitting diodes emitting at 440 nm with 93% peak internal quantum efficiency. The differential carrier lifetime is analyzed for various injection current densities from 5 A/cm

Desirable Characteristics of Hepatitis C Treatment Regimens: A Review of What We Have and What We Need.

Infectious diseases and therapy

Bidell MR, McLaughlin M, Faragon J, Morse C, Patel N.
PMID: 27384319
Infect Dis Ther. 2016 Sep;5(3):299-312. doi: 10.1007/s40121-016-0118-x. Epub 2016 Jul 06.

There have been dramatic advancements in the treatment of chronic hepatitis C (HCV) infection. This is largely due to the approval of several direct-acting antiviral agents (DAAs) from a variety of medication classes with novel mechanisms of action. These...

Systematics of the Carex aquatilis and C. lenticularis lineages: Geographically and ecologically divergent sister clades of Carex section Phacocystis (Cyperaceae).

American journal of botany

Dragon JA, Barrington DS.
PMID: 21622311
Am J Bot. 2009 Oct;96(10):1896-906. doi: 10.3732/ajb.0800404.

Carex aquatilis is a highly diverse and geographically widespread member of one of the largest genera of flowering plants, Carex, and is ideally suited for the study of the role of hybridization and niche partitioning in ecological speciation. Phylogenetic...

Quantitative Intracellular pH Determinations in Single Live Mammalian Spermatozoa Using the Ratiometric Dye SNARF-5F.

Frontiers in cell and developmental biology

Chávez JC, Darszon A, Treviño CL, Nishigaki T.
PMID: 32010689
Front Cell Dev Biol. 2020 Jan 17;7:366. doi: 10.3389/fcell.2019.00366. eCollection 2019.

Intracellular pH (pH

Design and Characterization of an "All-in-One" Lentiviral Vector System Combining Constitutive Anti-G.

Cancers

Zimmermann K, Kuehle J, Dragon AC, Galla M, Kloth C, Rudek LS, Sandalcioglu IE, Neyazi B, Moritz T, Meyer J, Rossig C, Altvater B, Eiz-Vesper B, Morgan MA, Abken H, Schambach A.
PMID: 32041222
Cancers (Basel). 2020 Feb 06;12(2). doi: 10.3390/cancers12020375.

Genetically modified T cells expressing chimeric antigen receptors (CARs) so far have mostly failed in the treatment of solid tumors owing to a number of limitations, including an immunosuppressive tumor microenvironment and insufficient CAR T cell activation and persistence....

Elevated Choroidal Thickness and Central Serous Chorioretinopathy in the Fellow Eyes of Patients with Circumscribed Choroidal Hemangioma.

Ocular oncology and pathology

Kim RS, Jain RR, Brown DM, Bretana ME, Kegley EN, Singer MA, Aragon AV, Schefler AC.
PMID: 30574490
Ocul Oncol Pathol. 2018 Nov;4(6):375-380. doi: 10.1159/000486864. Epub 2018 Apr 20.

OBJECTIVE: To determine whether increased choroidal thickness (CT) is associated with circumscribed choroidal hemangioma (CCH) and whether patients with CCH are predisposed to central serous chorioretinopathy (CSCR).METHODS: We performed a retrospective consecutive observational study of 15 fellow eyes of...

Impact of assessment of bone status before corrective surgery of lumbar spine in patients over 50 years old.

Open access rheumatology : research and reviews

Banse C, Ould-Slimane M, Foulongne E, Perez A, Avenel G, Daragon A, Vittecoq O.
PMID: 31123425
Open Access Rheumatol. 2019 May 06;11:111-115. doi: 10.2147/OARRR.S197218. eCollection 2019.

No abstract available.

Case series of massive direct oral anticoagulant ingestion - treatment and pharmacokinetics data.

European journal of clinical investigation

Delrue M, Chevillard L, Stépanian A, Dragoni A, Camoin-Jau L, Voicu S, Malissin I, Deye N, Gainnier M, Siguret V, Mégarbane B.
PMID: 35000196
Eur J Clin Invest. 2022 Jan 09;e13746. doi: 10.1111/eci.13746. Epub 2022 Jan 09.

BACKGROUND: Direct oral anticoagulants (DOAC) are widely used due to favourable benefit/risk ratio. However, consequences of massive ingestion have been poorly investigated.OBJECTIVES: We aimed to report outcome and pharmacokinetic parameters in patients who massively ingested DOACs.METHODS: We conducted a...

Mathematical model reveals that heterogeneity in the number of ion transporters regulates the fraction of mouse sperm capacitation.

PloS one

Aguado-García A, Priego-Espinosa DA, Aldana A, Darszon A, Martínez-Mekler G.
PMID: 34793454
PLoS One. 2021 Nov 18;16(11):e0245816. doi: 10.1371/journal.pone.0245816. eCollection 2021.

Capacitation is a complex maturation process mammalian sperm must undergo in the female genital tract to be able to fertilize an egg. This process involves, amongst others, physiological changes in flagellar beating pattern, membrane potential, intracellular ion concentrations and...

Epac activation induces an extracellular Ca.

Andrology

Mata-Martínez E, Sánchez-Tusie AA, Darszon A, Mayorga LS, Treviño CL, De Blas GA.
PMID: 33609309
Andrology. 2021 Jul;9(4):1227-1241. doi: 10.1111/andr.12989. Epub 2021 Mar 09.

BACKGROUND: The signaling pathways of the intracellular second messengers cAMP and CaOBJECTIVE: To identify the molecular entities involved in the CaMATERIALS AND METHODS: In capacitated human spermatozoa, we monitored CaRESULTS: Epac activation by 2'-O-Me-cAMP induced a CaDISCUSSION: Our results...

Caught in motion: human NTHL1 undergoes interdomain rearrangement necessary for catalysis.

Nucleic acids research

Carroll BL, Zahn KE, Hanley JP, Wallace SS, Dragon JA, Doublié S.
PMID: 34871433
Nucleic Acids Res. 2021 Dec 06; doi: 10.1093/nar/gkab1162. Epub 2021 Dec 06.

Base excision repair (BER) is the main pathway protecting cells from the continuous damage to DNA inflicted by reactive oxygen species. BER is initiated by DNA glycosylases, each of which repairs a particular class of base damage. NTHL1, a...

The evolution of mean arterial pressure in critically ill patients on vasopressors before and during a trial comparing a specific mean arterial pressure target to usual care.

BMC anesthesiology

Masse MH, Adhikari NKJ, Théroux X, Battista MC, D'Aragon F, Pinto R, Cohen A, Mayette M, St-Arnaud C, Kho M, Chassé M, Lebrasseur M, Watpool I, Porteous R, Wilcox ME, Lamontagne F.
PMID: 34979938
BMC Anesthesiol. 2022 Jan 03;22(1):6. doi: 10.1186/s12871-021-01529-w.

BACKGROUND: In randomized clinical controlled trials, the choice of usual care as the comparator may be associated with better clinician uptake of the study protocol and lead to more generalizable results. However, if care processes evolve to resemble the...

Showing 1 to 12 of 137 entries