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Diverse Immunological Factors Influencing Pathogenesis in Patients with COVID-19: A Review on Viral Dissemination, Immunotherapeutic Options to Counter Cytokine Storm and Inflammatory Responses.

Pathogens (Basel, Switzerland)

Rabaan AA, Al-Ahmed SH, Garout MA, Al-Qaaneh AM, Sule AA, Tirupathi R, Mutair AA, Alhumaid S, Hasan A, Dhawan M, Tiwari R, Sharun K, Mohapatra RK, Mitra S, Emran TB, Bilal M, Singh R, Alyami SA, Moni MA, Dhama K.
PMID: 34066983
Pathogens. 2021 May 07;10(5). doi: 10.3390/pathogens10050565.

The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though preventive vaccines and treatment methods are out on the market, a specific cure for the disease has...

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Rabaan AA, Al-Ahmed SH, Garout MA, et al. Diverse Immunological Factors Influencing Pathogenesis in Patients with COVID-19: A Review on Viral Dissemination, Immunotherapeutic Options to Counter Cytokine Storm and Inflammatory Responses. Pathogens. 2021;10(5)doi: 10.3390/pathogens10050565.
Rabaan, A. A., Al-Ahmed, S. H., Garout, M. A., Al-Qaaneh, A. M., Sule, A. A., Tirupathi, R., Mutair, A. A., Alhumaid, S., Hasan, A., Dhawan, M., Tiwari, R., Sharun, K., Mohapatra, R. K., Mitra, S., Emran, T. B., Bilal, M., Singh, R., Alyami, S. A., Moni, M. A., & Dhama, K. (2021). Diverse Immunological Factors Influencing Pathogenesis in Patients with COVID-19: A Review on Viral Dissemination, Immunotherapeutic Options to Counter Cytokine Storm and Inflammatory Responses. Pathogens (Basel, Switzerland), 10(5), . https://doi.org/10.3390/pathogens10050565
Rabaan, Ali A, et al. "Diverse Immunological Factors Influencing Pathogenesis in Patients with COVID-19: A Review on Viral Dissemination, Immunotherapeutic Options to Counter Cytokine Storm and Inflammatory Responses." Pathogens (Basel, Switzerland) vol. 10,5 (2021). doi: https://doi.org/10.3390/pathogens10050565
Rabaan AA, Al-Ahmed SH, Garout MA, Al-Qaaneh AM, Sule AA, Tirupathi R, Mutair AA, Alhumaid S, Hasan A, Dhawan M, Tiwari R, Sharun K, Mohapatra RK, Mitra S, Emran TB, Bilal M, Singh R, Alyami SA, Moni MA, Dhama K. Diverse Immunological Factors Influencing Pathogenesis in Patients with COVID-19: A Review on Viral Dissemination, Immunotherapeutic Options to Counter Cytokine Storm and Inflammatory Responses. Pathogens. 2021 May 07;10(5). doi: 10.3390/pathogens10050565. PMID: 34066983; PMCID: PMC8150955.
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Peak Systolic Blood Pressure During the Exercise Test: Reference Values by Sex and Age and Association With Mortality.

Hypertension (Dallas, Tex. : 1979)

Assaf Y, Barout A, Alhamid A, Al-Mouakeh A, Barillas-Lara MI, Fortin-Gamero S, Bonikowske AR, Pepine CJ, Allison TG.
PMID: 33866799
Hypertension. 2021 Jun;77(6):1906-1914. doi: 10.1161/HYPERTENSIONAHA.120.16570. Epub 2021 Apr 19.

[Figure: see text].

Cite
Assaf Y, Barout A, Alhamid A, et al. Peak Systolic Blood Pressure During the Exercise Test: Reference Values by Sex and Age and Association With Mortality. Hypertension. 2021;77(6):1906-1914doi: 10.1161/HYPERTENSIONAHA.120.16570.
Assaf, Y., Barout, A., Alhamid, A., Al-Mouakeh, A., Barillas-Lara, M. I., Fortin-Gamero, S., Bonikowske, A. R., Pepine, C. J., & Allison, T. G. (2021). Peak Systolic Blood Pressure During the Exercise Test: Reference Values by Sex and Age and Association With Mortality. Hypertension (Dallas, Tex. : 1979), 77(6), 1906-1914. https://doi.org/10.1161/HYPERTENSIONAHA.120.16570
Assaf, Yazan, et al. "Peak Systolic Blood Pressure During the Exercise Test: Reference Values by Sex and Age and Association With Mortality." Hypertension (Dallas, Tex. : 1979) vol. 77,6 (2021): 1906-1914. doi: https://doi.org/10.1161/HYPERTENSIONAHA.120.16570
Assaf Y, Barout A, Alhamid A, Al-Mouakeh A, Barillas-Lara MI, Fortin-Gamero S, Bonikowske AR, Pepine CJ, Allison TG. Peak Systolic Blood Pressure During the Exercise Test: Reference Values by Sex and Age and Association With Mortality. Hypertension. 2021 Jun;77(6):1906-1914. doi: 10.1161/HYPERTENSIONAHA.120.16570. Epub 2021 Apr 19. PMID: 33866799.
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5HT-2C agonist lorcaserin decreases cannabis self-administration in daily cannabis smokers.

Addiction biology

Arout CA, Cooper ZD, Reed SC, Foltin RW, Comer SD, Levin FR, Haney M.
PMID: 33389797
Addict Biol. 2021 Jul;26(4):e12993. doi: 10.1111/adb.12993. Epub 2021 Jan 03.

There are no FDA-approved treatments for cannabis use disorder (CUD). Preclinical research has shown that the 5HT-2C agonist lorcaserin attenuates cue-induced reinstatement of THC seeking and self-administration. The goal of this placebo-controlled, counterbalanced, within-subject human laboratory study was to...

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Arout CA, Cooper ZD, Reed SC, et al. 5HT-2C agonist lorcaserin decreases cannabis self-administration in daily cannabis smokers. Addict Biol. 2021;26(4):e12993doi: 10.1111/adb.12993.
Arout, C. A., Cooper, Z. D., Reed, S. C., Foltin, R. W., Comer, S. D., Levin, F. R., & Haney, M. (2021). 5HT-2C agonist lorcaserin decreases cannabis self-administration in daily cannabis smokers. Addiction biology, 26(4), e12993. https://doi.org/10.1111/adb.12993
Arout, Caroline A, et al. "5HT-2C agonist lorcaserin decreases cannabis self-administration in daily cannabis smokers." Addiction biology vol. 26,4 (2021): e12993. doi: https://doi.org/10.1111/adb.12993
Arout CA, Cooper ZD, Reed SC, Foltin RW, Comer SD, Levin FR, Haney M. 5HT-2C agonist lorcaserin decreases cannabis self-administration in daily cannabis smokers. Addict Biol. 2021 Jul;26(4):e12993. doi: 10.1111/adb.12993. Epub 2021 Jan 03. PMID: 33389797; PMCID: PMC8225547.
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A placebo-controlled investigation of the analgesic effects, abuse liability, safety and tolerability of a range of oral cannabidiol doses in healthy humans.

British journal of clinical pharmacology

Arout CA, Haney M, Herrmann ES, Bedi G, Cooper ZD.
PMID: 34223660
Br J Clin Pharmacol. 2021 Jul 05; doi: 10.1111/bcp.14973. Epub 2021 Jul 05.

AIMS: Preclinical studies demonstrate that cannabidiol (CBD) elicits an antinociceptive response in animal models of neuropathic pain; in humans, limited data are available to support such analgesic effects. Few studies have examined CBD's analgesic effects when administered without other...

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Arout CA, Haney M, Herrmann ES, et al. A placebo-controlled investigation of the analgesic effects, abuse liability, safety and tolerability of a range of oral cannabidiol doses in healthy humans. Br J Clin Pharmacol. 2021;doi: 10.1111/bcp.14973.
Arout, C. A., Haney, M., Herrmann, E. S., Bedi, G., & Cooper, Z. D. (2021). A placebo-controlled investigation of the analgesic effects, abuse liability, safety and tolerability of a range of oral cannabidiol doses in healthy humans. British journal of clinical pharmacology, . https://doi.org/10.1111/bcp.14973
Arout, Caroline A, et al. "A placebo-controlled investigation of the analgesic effects, abuse liability, safety and tolerability of a range of oral cannabidiol doses in healthy humans." British journal of clinical pharmacology vol. (2021). doi: https://doi.org/10.1111/bcp.14973
Arout CA, Haney M, Herrmann ES, Bedi G, Cooper ZD. A placebo-controlled investigation of the analgesic effects, abuse liability, safety and tolerability of a range of oral cannabidiol doses in healthy humans. Br J Clin Pharmacol. 2021 Jul 05; doi: 10.1111/bcp.14973. Epub 2021 Jul 05. PMID: 34223660.
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Lignocellulose Improves Protein and Amino Acid Digestibility in Roosters and Egg Hatchability in Broiler Breeders.

The journal of poultry science

Farran MT, Akilian HA, Hamoud AM, Barbour GW, Saoud IP.
PMID: 32908426
J Poult Sci. 2017 Jul 25;54(3):197-204. doi: 10.2141/jpsa.0160095.

The present work assessed the effect of supplementation of 0.8% dietary Arbocel

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Farran MT, Akilian HA, Hamoud AM, et al. Lignocellulose Improves Protein and Amino Acid Digestibility in Roosters and Egg Hatchability in Broiler Breeders. J Poult Sci. 2017;54(3):197-204doi: 10.2141/jpsa.0160095.
Farran, M. T., Akilian, H. A., Hamoud, A. M., Barbour, G. W., & Saoud, I. P. (2017). Lignocellulose Improves Protein and Amino Acid Digestibility in Roosters and Egg Hatchability in Broiler Breeders. The journal of poultry science, 54(3), 197-204. https://doi.org/10.2141/jpsa.0160095
Farran, Mohamad T, et al. "Lignocellulose Improves Protein and Amino Acid Digestibility in Roosters and Egg Hatchability in Broiler Breeders." The journal of poultry science vol. 54,3 (2017): 197-204. doi: https://doi.org/10.2141/jpsa.0160095
Farran MT, Akilian HA, Hamoud AM, Barbour GW, Saoud IP. Lignocellulose Improves Protein and Amino Acid Digestibility in Roosters and Egg Hatchability in Broiler Breeders. J Poult Sci. 2017 Jul 25;54(3):197-204. doi: 10.2141/jpsa.0160095. PMID: 32908426; PMCID: PMC7477211.
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Two-dimensional phase unwrapping using a hybrid genetic algorithm.

Applied optics

Karout SA, Gdeisat MA, Burton DR, Lalor MJ.
PMID: 17279161
Appl Opt. 2007 Feb 10;46(5):730-43. doi: 10.1364/ao.46.000730.

A novel hybrid genetic algorithm (HGA) is proposed to solve the branch-cut phase unwrapping problem. It employs both local and global search methods. The local search is implemented by using the nearest-neighbor method, whereas the global search is performed...

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Karout SA, Gdeisat MA, Burton DR, et al. Two-dimensional phase unwrapping using a hybrid genetic algorithm. Appl Opt. 2007;46(5):730-43doi: 10.1364/ao.46.000730.
Karout, S. A., Gdeisat, M. A., Burton, D. R., & Lalor, M. J. (2007). Two-dimensional phase unwrapping using a hybrid genetic algorithm. Applied optics, 46(5), 730-43. https://doi.org/10.1364/ao.46.000730
Karout, Salah A, et al. "Two-dimensional phase unwrapping using a hybrid genetic algorithm." Applied optics vol. 46,5 (2007): 730-43. doi: https://doi.org/10.1364/ao.46.000730
Karout SA, Gdeisat MA, Burton DR, Lalor MJ. Two-dimensional phase unwrapping using a hybrid genetic algorithm. Appl Opt. 2007 Feb 10;46(5):730-43. doi: 10.1364/ao.46.000730. PMID: 17279161.
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Residue vector, an approach to branch-cut placement in phase unwrapping: theoretical study.

Applied optics

Karout SA, Gdeisat MA, Burton DR, Lalor MJ.
PMID: 17609719
Appl Opt. 2007 Jul 20;46(21):4712-27. doi: 10.1364/ao.46.004712.

What we believe to be a novel technique of branch-cut placement in the phase unwrapping is proposed. This approach is based on what we named residue vector, which is generated by a residue in a wrapped phase map and...

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Karout SA, Gdeisat MA, Burton DR, et al. Residue vector, an approach to branch-cut placement in phase unwrapping: theoretical study. Appl Opt. 2007;46(21):4712-27doi: 10.1364/ao.46.004712.
Karout, S. A., Gdeisat, M. A., Burton, D. R., & Lalor, M. J. (2007). Residue vector, an approach to branch-cut placement in phase unwrapping: theoretical study. Applied optics, 46(21), 4712-27. https://doi.org/10.1364/ao.46.004712
Karout, Salah A, et al. "Residue vector, an approach to branch-cut placement in phase unwrapping: theoretical study." Applied optics vol. 46,21 (2007): 4712-27. doi: https://doi.org/10.1364/ao.46.004712
Karout SA, Gdeisat MA, Burton DR, Lalor MJ. Residue vector, an approach to branch-cut placement in phase unwrapping: theoretical study. Appl Opt. 2007 Jul 20;46(21):4712-27. doi: 10.1364/ao.46.004712. PMID: 17609719.
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Current vaccine approaches and emerging strategies against herpes simplex virus (HSV).

Expert review of vaccines

Wijesinghe VN, Farouk IA, Zabidi NZ, Puniyamurti A, Choo WS, Lal SK.
PMID: 34296960
Expert Rev Vaccines. 2021 Sep;20(9):1077-1096. doi: 10.1080/14760584.2021.1960162. Epub 2021 Aug 09.

No abstract available.

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Wijesinghe VN, Farouk IA, Zabidi NZ, et al. Current vaccine approaches and emerging strategies against herpes simplex virus (HSV). Expert Rev Vaccines. 2021;20(9):1077-1096doi: 10.1080/14760584.2021.1960162.
Wijesinghe, V. N., Farouk, I. A., Zabidi, N. Z., Puniyamurti, A., Choo, W. S., & Lal, S. K. (2021). Current vaccine approaches and emerging strategies against herpes simplex virus (HSV). Expert review of vaccines, 20(9), 1077-1096. https://doi.org/10.1080/14760584.2021.1960162
Wijesinghe, Vindya Nilakshi, et al. "Current vaccine approaches and emerging strategies against herpes simplex virus (HSV)." Expert review of vaccines vol. 20,9 (2021): 1077-1096. doi: https://doi.org/10.1080/14760584.2021.1960162
Wijesinghe VN, Farouk IA, Zabidi NZ, Puniyamurti A, Choo WS, Lal SK. Current vaccine approaches and emerging strategies against herpes simplex virus (HSV). Expert Rev Vaccines. 2021 Sep;20(9):1077-1096. doi: 10.1080/14760584.2021.1960162. Epub 2021 Aug 09. PMID: 34296960.
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Multisystem Inflammatory Syndrome in an Adult (MIS-A) Successfully Treated with Anakinra and Glucocorticoids.

Microorganisms

Cattaneo P, Volpe A, Cardellino CS, Riccardi N, Bertoli G, Ursini T, Ustalli A, Lodi G, Daroui I, Angheben A.
PMID: 34203277
Microorganisms. 2021 Jun 28;9(7). doi: 10.3390/microorganisms9071393.

During the current SARS-CoV-2 pandemic, a novel syndrome termed "multisystem inflammatory syndrome in children" (MIS-C) has emerged. MIS-C was linked to COVID-19 and shared some features with Kawasaki disease and Toxic Shock Syndrome, with a common pathogenetic substrate of...

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Cattaneo P, Volpe A, Cardellino CS, et al. Multisystem Inflammatory Syndrome in an Adult (MIS-A) Successfully Treated with Anakinra and Glucocorticoids. Microorganisms. 2021;9(7)doi: 10.3390/microorganisms9071393.
Cattaneo, P., Volpe, A., Cardellino, C. S., Riccardi, N., Bertoli, G., Ursini, T., Ustalli, A., Lodi, G., Daroui, I., & Angheben, A. (2021). Multisystem Inflammatory Syndrome in an Adult (MIS-A) Successfully Treated with Anakinra and Glucocorticoids. Microorganisms, 9(7), . https://doi.org/10.3390/microorganisms9071393
Cattaneo, Paolo, et al. "Multisystem Inflammatory Syndrome in an Adult (MIS-A) Successfully Treated with Anakinra and Glucocorticoids." Microorganisms vol. 9,7 (2021). doi: https://doi.org/10.3390/microorganisms9071393
Cattaneo P, Volpe A, Cardellino CS, Riccardi N, Bertoli G, Ursini T, Ustalli A, Lodi G, Daroui I, Angheben A. Multisystem Inflammatory Syndrome in an Adult (MIS-A) Successfully Treated with Anakinra and Glucocorticoids. Microorganisms. 2021 Jun 28;9(7). doi: 10.3390/microorganisms9071393. PMID: 34203277; PMCID: PMC8305807.
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Impetigo herpetiformis during the puerperium triggered by secondary hypoparathyroidism: a case report.

Cases journal

Fouda UM, Fouda RM, Ammar HM, Salem M, Darouti ME.
PMID: 20072676
Cases J. 2009 Dec 16;2:9338. doi: 10.1186/1757-1626-2-9338.

A 38-year-old multiparous woman with post thyroidectomy hypoparathyroidism developed pruritic erythematous patches with multiple pustules on its margins on her thighs and groin accompanied by fever few days after delivery by caesarean section. Impetigo herpetiformis was diagnosed based on...

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Fouda UM, Fouda RM, Ammar HM, et al. Impetigo herpetiformis during the puerperium triggered by secondary hypoparathyroidism: a case report. Cases J. 2009;2:9338doi: 10.1186/1757-1626-2-9338.
Fouda, U. M., Fouda, R. M., Ammar, H. M., Salem, M., & Darouti, M. E. (2009). Impetigo herpetiformis during the puerperium triggered by secondary hypoparathyroidism: a case report. Cases journal, 29338. https://doi.org/10.1186/1757-1626-2-9338
Fouda, Usama M, et al. "Impetigo herpetiformis during the puerperium triggered by secondary hypoparathyroidism: a case report." Cases journal vol. 2 (2009): 9338. doi: https://doi.org/10.1186/1757-1626-2-9338
Fouda UM, Fouda RM, Ammar HM, Salem M, Darouti ME. Impetigo herpetiformis during the puerperium triggered by secondary hypoparathyroidism: a case report. Cases J. 2009 Dec 16;2:9338. doi: 10.1186/1757-1626-2-9338. PMID: 20072676; PMCID: PMC2806392.
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A Health Education Intervention Study on Tobacco Consumption Among the Urban Slum Residents of Central India.

International journal of preventive medicine

Sharma A, Gupta SK, Agrawal S, Gupta SK, Sarouthia S.
PMID: 31360343
Int J Prev Med. 2019 Jun 07;10:96. doi: 10.4103/ijpvm.IJPVM_141_18. eCollection 2019.

BACKGROUND: Tobacco is one of the world's leading avoidable causes of premature death, disease, and disability. According to the World Health Organization (WHO) survey 2020, there are about 120 million tobacco users in India, and WHO estimates that about...

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Sharma A, Gupta SK, Agrawal S, et al. A Health Education Intervention Study on Tobacco Consumption Among the Urban Slum Residents of Central India. Int J Prev Med. 2019;10:96doi: 10.4103/ijpvm.IJPVM_141_18.
Sharma, A., Gupta, S. K., Agrawal, S., Gupta, S. K., & Sarouthia, S. (2019). A Health Education Intervention Study on Tobacco Consumption Among the Urban Slum Residents of Central India. International journal of preventive medicine, 1096. https://doi.org/10.4103/ijpvm.IJPVM_141_18
Sharma, Anshuman, et al. "A Health Education Intervention Study on Tobacco Consumption Among the Urban Slum Residents of Central India." International journal of preventive medicine vol. 10 (2019): 96. doi: https://doi.org/10.4103/ijpvm.IJPVM_141_18
Sharma A, Gupta SK, Agrawal S, Gupta SK, Sarouthia S. A Health Education Intervention Study on Tobacco Consumption Among the Urban Slum Residents of Central India. Int J Prev Med. 2019 Jun 07;10:96. doi: 10.4103/ijpvm.IJPVM_141_18. eCollection 2019. PMID: 31360343; PMCID: PMC6592133.
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Peak Systolic Blood Pressure During the Exercise Test: Reference Values by Sex and Age and Association With Mortality.

Hypertension (Dallas, Tex. : 1979)

Assaf Y, Barout A, Alhamid A, Al-Mouakeh A, Barillas-Lara MI, Fortin-Gamero S, Bonikowske AR, Pepine CJ, Allison TG.
PMID: 33866799
Hypertension. 2021 Jun;77(6):1906-1914. doi: 10.1161/HYPERTENSIONAHA.120.16570. Epub 2021 Apr 19.

[Figure: see text].

Cite
Assaf Y, Barout A, Alhamid A, et al. Peak Systolic Blood Pressure During the Exercise Test: Reference Values by Sex and Age and Association With Mortality. Hypertension. 2021;77(6):1906-1914doi: 10.1161/HYPERTENSIONAHA.120.16570.
Assaf, Y., Barout, A., Alhamid, A., Al-Mouakeh, A., Barillas-Lara, M. I., Fortin-Gamero, S., Bonikowske, A. R., Pepine, C. J., & Allison, T. G. (2021). Peak Systolic Blood Pressure During the Exercise Test: Reference Values by Sex and Age and Association With Mortality. Hypertension (Dallas, Tex. : 1979), 77(6), 1906-1914. https://doi.org/10.1161/HYPERTENSIONAHA.120.16570
Assaf, Yazan, et al. "Peak Systolic Blood Pressure During the Exercise Test: Reference Values by Sex and Age and Association With Mortality." Hypertension (Dallas, Tex. : 1979) vol. 77,6 (2021): 1906-1914. doi: https://doi.org/10.1161/HYPERTENSIONAHA.120.16570
Assaf Y, Barout A, Alhamid A, Al-Mouakeh A, Barillas-Lara MI, Fortin-Gamero S, Bonikowske AR, Pepine CJ, Allison TG. Peak Systolic Blood Pressure During the Exercise Test: Reference Values by Sex and Age and Association With Mortality. Hypertension. 2021 Jun;77(6):1906-1914. doi: 10.1161/HYPERTENSIONAHA.120.16570. Epub 2021 Apr 19. PMID: 33866799.
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