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Showing 1 to 12 of 294 entries
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Sputum Gene Expression of IL-13 Receptor α2 Chain Correlates with Airflow Obstruction and Helper T-Cell Type 2 Inflammation in Asthma.

Annals of the American Thoracic Society

Nezgovorova V, Liu Q, Hu B, Villalobos JL, Yan X, Niu N, Holm C, Grant NP, Marone S, Ravage-Mass L, Lee CG, Elias JA, Cohn L, Chupp GL.
PMID: 27027964
Ann Am Thorac Soc. 2016 Mar;13:S96-7. doi: 10.1513/AnnalsATS.201509-611MG.

BACKGROUND: BRP-39/YKL-40 is a chitinase-like protein that plays a critical role in IL-13-induced inflammation. It correlates positively with asthma severity and airway remodeling ( 1 ) via binding to IL-13 receptor α2 chain (IL-13Rα2). Because the relationship of IL-13Rα2...

Substance use disorders in military veterans: prevalence and treatment challenges.

Substance abuse and rehabilitation

Teeters JB, Lancaster CL, Brown DG, Back SE.
PMID: 28919834
Subst Abuse Rehabil. 2017 Aug 30;8:69-77. doi: 10.2147/SAR.S116720. eCollection 2017.

Substance use disorders (SUDs) are a significant problem among our nation's military veterans. In the following overview, we provide information on the prevalence of SUDs among military veterans, clinical characteristics of SUDs, options for screening and evidence-based treatment, as...

Sodium-glucose cotransporter-2 inhibition and acidosis in patients with type 2 diabetes: a review of US FDA data and possible conclusions.

International journal of nephrology and renovascular disease

D'Elia JA, Segal AR, Bayliss GP, Weinrauch LA.
PMID: 28670136
Int J Nephrol Renovasc Dis. 2017 Jun 15;10:153-158. doi: 10.2147/IJNRD.S135899. eCollection 2017.

OBJECTIVE: To evaluate whether adverse event reports to the US Food and Drug Administration on incidents of ketoacidosis from use of sodium glucose cotransport inhibitors (SGLT2 inhibitors) provide insight into ways this new class of drugs is being prescribed...

Certifying and measuring competency in the United States.

Archives of physical medicine and rehabilitation

DeLisa JA.
PMID: 10987169
Arch Phys Med Rehabil. 2000 Sep;81(9):1236-41. doi: 10.1053/apmr.2000.17876.

No abstract available.

Peer review of clinical research applications: leveling the playing field.

The journal of spinal cord medicine

DeLisa JA.
PMID: 11944779
J Spinal Cord Med. 2001;24(4):229. doi: 10.1080/10790268.2001.11753578.

No abstract available.

Diabetic microvascular complications: possible targets for improved macrovascular outcomes.

International journal of nephrology and renovascular disease

D'Elia JA, Bayliss G, Roshan B, Maski M, Gleason RE, Weinrauch LA.
PMID: 21694944
Int J Nephrol Renovasc Dis. 2011;4:1-15. doi: 10.2147/IJNRD.S14716. Epub 2010 Dec 22.

The results of recent outcome trials challenge hypotheses that tight control of both glycohemoglobin and blood pressure diminishes macrovascular events and survival among type 2 diabetic patients. Relevant questions exist regarding the adequacy of glycohemoglobin alone as a measure...

Commentary: More implications of the 2008 amendments to the Americans with Disabilities Act: influencing institutional policies, practices, and procedures.

Academic medicine : journal of the Association of American Medical Colleges

DeLisa J, Silverstein R, Thomas P.
PMID: 21613889
Acad Med. 2011 Jun;86(6):677-9. doi: 10.1097/ACM.0b013e318217ee74.

The Americans with Disabilities Act (ADA) is a civil rights law designed to ensure that qualified individuals with disabilities are not discriminated against by covered entities. Under the ADA, colleges of medicine were expected to focus their attention on...

Smoking and outcomes in kidney transplant recipients: a post hoc survival analysis of the FAVORIT trial.

International journal of nephrology and renovascular disease

Weinrauch LA, Claggett B, Liu J, Finn PV, Weir MR, Weiner DE, D'Elia JA.
PMID: 29760559
Int J Nephrol Renovasc Dis. 2018 Apr 27;11:155-164. doi: 10.2147/IJNRD.S161001. eCollection 2018.

BACKGROUND: Tobacco use remains an international health problem with between 10% and 40% of adults currently using tobacco. Given the rising number of patients either awaiting or having received a kidney transplant and the absence of smoking cessation as...

Stable Isotope-Resolved Metabolomic Differences between Hormone-Responsive and Triple-Negative Breast Cancer Cell Lines.

International journal of breast cancer

Winnike JH, Stewart DA, Pathmasiri WW, McRitchie SL, Sumner SJ.
PMID: 30363973
Int J Breast Cancer. 2018 Sep 30;2018:2063540. doi: 10.1155/2018/2063540. eCollection 2018.

PURPOSE: To conduct an exploratory study to identify mechanisms that differentiate Luminal A (BT474 and MCF-7) and triple-negative (MDA-MB-231 and MDA-MB-468) breast cancer (BCa) cell lines to potentially provide novel therapeutic targets based on differences in energy utilization.METHODS: Cells...

Author Correction: Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.

Nature communications

Jaroentomeechai T, Stark JC, Natarajan A, Glasscock CJ, Yates LE, Hsu KJ, Mrksich M, Jewett MC, DeLisa MP.
PMID: 30127449
Nat Commun. 2018 Aug 20;9(1):3396. doi: 10.1038/s41467-018-05620-8.

The original version of this Article contained an error in Figure 2, wherein the bottom right western blot panel in Figure 2a was blank. This has now been corrected in both the PDF and HTML versions of the Article.

Proposed roadmap to stepwise integration of genetics in family medicine and clinical research.

Clinical and translational medicine

Houwink EJ, Sollie AW, Numans ME, Cornel MC.
PMID: 23415259
Clin Transl Med. 2013 Feb 16;2(1):5. doi: 10.1186/2001-1326-2-5.

We propose A step-by-step roadmap to integrate genetics in the Electronic Patient Record in Family Medicine and clinical research. This could make urgent operationalization of readily available genetic knowledge feasible in clinical research and consequently improved medical care.Improving genomic...

Engineering a new generation of carbohydrate-based vaccines.

Current opinion in chemical engineering

Weyant KB, Mills DC, DeLisa MP.
PMID: 30568873
Curr Opin Chem Eng. 2018 Mar;19:77-85. doi: 10.1016/j.coche.2017.12.009. Epub 2018 Jan 11.

Recent advances in chemical synthesis, conjugation chemistry, engineered biosynthesis, and formulation design have spawned a new generation of vaccines that incorporate carbohydrate antigens. By providing better immunity against a variety of pathogens or malignant cells and lowering the cost...

Showing 1 to 12 of 294 entries