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Showing 1 to 12 of 276 entries
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Sox3 Is Required for Gonadal Function, but Not Sex Determination, in Males and Females

STEM and males

Meeks JJ, Raverot G.
GSID: x-bGRcxqnxQJ
J Weiss, JJ Meeks, L Hurley, G Raverot… - … and Cellular Biology, 2003 - Am Soc Microbiol

… The targeting vector was electroporated into R1 embryonic stem (… Males were housed with pairs of female mice for 14 to 20 … For sperm collection, proven breeder males were sacrificed, …

Validity of indirect comparison for estimating efficacy of competing interventions: empirical evidence from published meta-analyses

interventions

Altman DG, Deeks JJ, Song F.
GSID: DP63FMqMs68J
F Song, DG Altman, AM Glenny, JJ Deeks - Bmj, 2003 - bmj.com

Objective: To determine the validity of adjusted indirect comparisons by using data from published meta-analyses of randomised trials. Design: Direct comparison of different …

Raising the Bar: Further Improvement is Required to Make More Test Accuracy Research Fit for Decision-making.

Clinical chemistry

Deeks JJ.
PMID: 28606914
Clin Chem. 2017 Aug;63(8):1315-1317. doi: 10.1373/clinchem.2017.274431. Epub 2017 Jun 12.

No abstract available.

Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial.

PLoS pathogens

Serrano-Villar S, Sainz T, Ma ZM, Utay NS, Chun TW, Mann S, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Deeks SG, Landay A, Pollard RB, Miller CJ, Moreno S, Asmuth DM.
PMID: 27015639
PLoS Pathog. 2016 Mar 25;12(3):e1005540. doi: 10.1371/journal.ppat.1005540. eCollection 2016 Mar.

No abstract available.

A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals.

Pathogens & immunity

Cockerham LR, Yukl SA, Harvill K, Somsouk M, Joshi SK, Sinclair E, Liegler T, Hoh R, Lyons S, Hunt PW, Rupert A, Sereti I, Morcock DR, Rhodes A, Emson C, Hellerstein MK, Estes JD, Lewin S, Deeks SG, Hatano H.
PMID: 28936485
Pathog Immun. 2017;2(3):310-334. doi: 10.20411/pai.v2i3.207. Epub 2017 Aug 02.

BACKGROUND: In HIV infection, lymphoid tissue is disrupted by fibrosis. Angiotensin converting enzyme inhibitors have anti-fibrotic properties. We completed a pilot study to assess whether the addition of lisinopril to antiretroviral therapy (ART) reverses fibrosis of gut tissue, and...

Issues relating to study design and risk of bias when including non-randomized studies in systematic reviews on the effects of interventions.

Research synthesis methods

Higgins JP, Ramsay C, Reeves BC, Deeks JJ, Shea B, Valentine JC, Tugwell P, Wells G.
PMID: 26053536
Res Synth Methods. 2013 Mar;4(1):12-25. doi: 10.1002/jrsm.1056. Epub 2012 Sep 25.

Non-randomized studies may provide valuable evidence on the effects of interventions. They are the main source of evidence on the intended effects of some types of interventions and often provide the only evidence about the effects of interventions on...

Spatial and temporal regulation of the pesticide dieldrin within industrial catchments.

The Science of the total environment

Mehar AA, Wright J, Leeks GJ, Wass P, Osborn D.
PMID: 10847166
Sci Total Environ. 2000 May 05;251:255-63. doi: 10.1016/s0048-9697(00)00388-0.

The river catchments of south Yorkshire support a very high density of wool processing industries. Dieldrin was once used as a moth proofing agent, as a sheep dip, and as a pesticide to protect wool fleeces during storage and...

Initial Organic Products of Fixation of [N]Dinitrogen by Root Nodules of Soybean (Glycine max).

Plant physiology

Meeks JC, Wolk CP, Schilling N, Shaffer PW.
PMID: 16660438
Plant Physiol. 1978 Jun;61(6):980-3. doi: 10.1104/pp.61.6.980.

When detached soybean Glycine max (L.) Merr. cv. Hark, nodules assimilate [(13)N]N(2), the initial organic product of fixation is glutamine; glutamate becomes more highly radioactive than glutamine within 1 minute; (13)N in alanine becoms detectable at 1 minute of...

Two-way Bayesian hierarchical phylogenetic models: An application to the co-evolution of gp120 and gp41 during and after enfuvirtide treatment.

Computational statistics & data analysis

Kitchen CM, Kroll J, Kuritzkes DR, Bloomquist E, Deeks SG, Suchard MA.
PMID: 20442796
Comput Stat Data Anal. 2009 Jan 15;53(3):766-775. doi: 10.1016/j.csda.2008.06.007.

Enfuvirtide (ENF) is a fusion inhibitor that prevents the entry of HIV virions into target cells. Studying the characteristics of viral evolution during treatment and after a treatment interruption can lend insight into the mechanisms of viral evolution and...

Carotid Intima-Media Thickness Progression in HIV-Infected Adults Occurs Preferentially at the Carotid Bifurcation and Is Predicted by Inflammation.

Journal of the American Heart Association

Hsue PY, Scherzer R, Hunt PW, Schnell A, Bolger AF, Kalapus SC, Maka K, Martin JN, Ganz P, Deeks SG.
PMID: 23130122
J Am Heart Assoc. 2012 Apr;1(2). doi: 10.1161/JAHA.111.000422. Epub 2012 Apr 24.

BACKGROUND: Shear stress gradients and inflammation have been causally associated with atherosclerosis development in carotid bifurcation regions. The mechanism underlying higher levels of carotid intima-media thickness observed among HIV-infected individuals remains unknown.METHODS AND RESULTS: We measured carotid intima-media thickness...

Summary of the National Advisory Committee on Immunization's updated recommendations on human papillomavirus (HPV) vaccines: Nine-valent human papillomavirus (HPV) of minimum intervals between doses in the HPV immunization schedule.

Canada communicable disease report = Releve des maladies transmissibles au Canada

Tunis MC, Deeks SL.
PMID: 29770021
Can Commun Dis Rep. 2016 Jul 07;42(7):149-151. doi: 10.14745/ccdr.v42i07a03. eCollection 2016 Jul 07.

BACKGROUND: Human papillomavirus (HPV) infections are the most common sexually transmitted infections, and in the absence of vaccination it is estimated that 75 percent of sexually active Canadians will have an HPV infection at some point in their lives....

Assessing vaccine safety within Ontario's Universal Influenza Immunization Program, 2012-2013 to 2014-2015.

Canada communicable disease report = Releve des maladies transmissibles au Canada

Harris T, Wong K, Nair J, Fediurek J, Deeks SL.
PMID: 29770028
Can Commun Dis Rep. 2016 Sep 01;42(9):181-186. doi: 10.14745/ccdr.v42i09a04. eCollection 2016 Sep 01.

BACKGROUND: Influenza vaccine is recommended to prevent influenza-related morbidity and mortality. Post-marketing surveillance of adverse events following influenza vaccine is essential to monitor vaccine safety, inform immunization program planning and evaluation, and build confidence in immunization.OBJECTIVE: To summarize adverse...

Showing 1 to 12 of 276 entries