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Developing a prototype system for integrating pharmacogenomics findings into clinical practice.

Journal of personalized medicine

Overby CL, Tarczy-Hornoch P, Kalet IJ, Thummel KE, Smith JW, Del Fiol G, Fenstermacher D, Devine EB.
PMID: 23741623
J Pers Med. 2012 Nov 20;2(4):241-56. doi: 10.3390/jpm2040241.

Findings from pharmacogenomics (PGx) studies have the potential to be applied to individualize drug therapy to improve efficacy and reduce adverse drug events. Researchers have identified factors influencing uptake of genomics in medicine, but little is known about the...

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Overby CL, Tarczy-Hornoch P, Kalet IJ, et al. Developing a prototype system for integrating pharmacogenomics findings into clinical practice. J Pers Med. 2012;2(4):241-56doi: 10.3390/jpm2040241.
Overby, C. L., Tarczy-Hornoch, P., Kalet, I. J., Thummel, K. E., Smith, J. W., Del Fiol, G., Fenstermacher, D., & Devine, E. B. (2012). Developing a prototype system for integrating pharmacogenomics findings into clinical practice. Journal of personalized medicine, 2(4), 241-56. https://doi.org/10.3390/jpm2040241
Overby, Casey Lynnette, et al. "Developing a prototype system for integrating pharmacogenomics findings into clinical practice." Journal of personalized medicine vol. 2,4 (2012): 241-56. doi: https://doi.org/10.3390/jpm2040241
Overby CL, Tarczy-Hornoch P, Kalet IJ, Thummel KE, Smith JW, Del Fiol G, Fenstermacher D, Devine EB. Developing a prototype system for integrating pharmacogenomics findings into clinical practice. J Pers Med. 2012 Nov 20;2(4):241-56. doi: 10.3390/jpm2040241. PMID: 23741623; PMCID: PMC3670105.
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The knowledge authoring tool: an XML-based knowledge acquisition environment.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

Hulse NC, Rocha RA, Del Fiol G, Bradshaw RL, Hanna TP, Roemer LK.
PMID: 17271000
Conf Proc IEEE Eng Med Biol Soc. 2004;2004:3350-3. doi: 10.1109/IEMBS.2004.1403941.

As part of an enterprise effort to develop new clinical information systems at Intermountain Health Care, we are developing a Knowledge Authoring Tool that facilitates the development of medical knowledge. At present, users of the application can compose order...

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Hulse NC, Rocha RA, Del Fiol G, et al. The knowledge authoring tool: an XML-based knowledge acquisition environment. Conf Proc IEEE Eng Med Biol Soc. 2004;2004:3350-3doi: 10.1109/IEMBS.2004.1403941.
Hulse, N. C., Rocha, R. A., Del Fiol, G., Bradshaw, R. L., Hanna, T. P., & Roemer, L. K. (2004). The knowledge authoring tool: an XML-based knowledge acquisition environment. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 20043350-3. https://doi.org/10.1109/IEMBS.2004.1403941
Hulse, N C, et al. "The knowledge authoring tool: an XML-based knowledge acquisition environment." Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference vol. 2004 (2004): 3350-3. doi: https://doi.org/10.1109/IEMBS.2004.1403941
Hulse NC, Rocha RA, Del Fiol G, Bradshaw RL, Hanna TP, Roemer LK. The knowledge authoring tool: an XML-based knowledge acquisition environment. Conf Proc IEEE Eng Med Biol Soc. 2004;2004:3350-3. doi: 10.1109/IEMBS.2004.1403941. PMID: 17271000.
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"On-demand" access to a multi-purpose collection of best practice standards.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

Del Fiol G, Rocha RA, Washburn J, Rhodes J, Hulse N, Bradshaw RL, Roemer LK.
PMID: 17270998
Conf Proc IEEE Eng Med Biol Soc. 2004;2004:3342-5. doi: 10.1109/IEMBS.2004.1403939.

On-demand" information has been chosen by clinicians as one of their preferred modes of interaction with computers when in need of information about evidence-based practices. However, most of the clinicians' information needs remain unmet, especially due to a lack...

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Del Fiol G, Rocha RA, Washburn J, et al. "On-demand" access to a multi-purpose collection of best practice standards. Conf Proc IEEE Eng Med Biol Soc. 2004;2004:3342-5doi: 10.1109/IEMBS.2004.1403939.
Del Fiol, G., Rocha, R. A., Washburn, J., Rhodes, J., Hulse, N., Bradshaw, R. L., & Roemer, L. K. (2004). "On-demand" access to a multi-purpose collection of best practice standards. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 20043342-5. https://doi.org/10.1109/IEMBS.2004.1403939
Del Fiol, G, et al. ""On-demand" access to a multi-purpose collection of best practice standards." Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference vol. 2004 (2004): 3342-5. doi: https://doi.org/10.1109/IEMBS.2004.1403939
Del Fiol G, Rocha RA, Washburn J, Rhodes J, Hulse N, Bradshaw RL, Roemer LK. "On-demand" access to a multi-purpose collection of best practice standards. Conf Proc IEEE Eng Med Biol Soc. 2004;2004:3342-5. doi: 10.1109/IEMBS.2004.1403939. PMID: 17270998.
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Prospects for the Use of New Technologies to Combat Multidrug-Resistant Bacteria.

Frontiers in pharmacology

Lima R, Del Fiol FS, Balcão VM.
PMID: 31293420
Front Pharmacol. 2019 Jun 21;10:692. doi: 10.3389/fphar.2019.00692. eCollection 2019.

The increasing use of antibiotics is being driven by factors such as the aging of the population, increased occurrence of infections, and greater prevalence of chronic diseases that require antimicrobial treatment. The excessive and unnecessary use of antibiotics in...

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Lima R, Del Fiol FS, Balcão VM. Prospects for the Use of New Technologies to Combat Multidrug-Resistant Bacteria. Front Pharmacol. 2019;10:692doi: 10.3389/fphar.2019.00692.
Lima, R., Del Fiol, F. S., & Balcão, V. M. (2019). Prospects for the Use of New Technologies to Combat Multidrug-Resistant Bacteria. Frontiers in pharmacology, 10692. https://doi.org/10.3389/fphar.2019.00692
Lima, Renata, et al. "Prospects for the Use of New Technologies to Combat Multidrug-Resistant Bacteria." Frontiers in pharmacology vol. 10 (2019): 692. doi: https://doi.org/10.3389/fphar.2019.00692
Lima R, Del Fiol FS, Balcão VM. Prospects for the Use of New Technologies to Combat Multidrug-Resistant Bacteria. Front Pharmacol. 2019 Jun 21;10:692. doi: 10.3389/fphar.2019.00692. eCollection 2019. PMID: 31293420; PMCID: PMC6598392.
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Data standards for interoperability of care team information to support care coordination of complex pediatric patients.

Journal of biomedical informatics

Ranade-Kharkar P, Narus SP, Anderson GL, Conway T, Del Fiol G.
PMID: 30017975
J Biomed Inform. 2018 Sep;85:1-9. doi: 10.1016/j.jbi.2018.07.009. Epub 2018 Jul 12.

OBJECTIVE: Seamless access to information about the individuals and organizations involved in the care of a specific patient ("care teams") is crucial to effective and efficient care coordination. This is especially true for vulnerable and complex patient populations such...

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Ranade-Kharkar P, Narus SP, Anderson GL, et al. Data standards for interoperability of care team information to support care coordination of complex pediatric patients. J Biomed Inform. 2018;85:1-9doi: 10.1016/j.jbi.2018.07.009.
Ranade-Kharkar, P., Narus, S. P., Anderson, G. L., Conway, T., & Del Fiol, G. (2018). Data standards for interoperability of care team information to support care coordination of complex pediatric patients. Journal of biomedical informatics, 851-9. https://doi.org/10.1016/j.jbi.2018.07.009
Ranade-Kharkar, Pallavi, et al. "Data standards for interoperability of care team information to support care coordination of complex pediatric patients." Journal of biomedical informatics vol. 85 (2018): 1-9. doi: https://doi.org/10.1016/j.jbi.2018.07.009
Ranade-Kharkar P, Narus SP, Anderson GL, Conway T, Del Fiol G. Data standards for interoperability of care team information to support care coordination of complex pediatric patients. J Biomed Inform. 2018 Sep;85:1-9. doi: 10.1016/j.jbi.2018.07.009. Epub 2018 Jul 12. PMID: 30017975.
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The potential for leveraging machine learning to filter medication alerts.

Journal of the American Medical Informatics Association : JAMIA

Liu S, Kawamoto K, Del Fiol G, Weir C, Malone DC, Reese TJ, Morgan K, ElHalta D, Abdelrahman S.
PMID: 34990507
J Am Med Inform Assoc. 2022 Jan 05; doi: 10.1093/jamia/ocab292. Epub 2022 Jan 05.

OBJECTIVE: To evaluate the potential for machine learning to predict medication alerts that might be ignored by a user, and intelligently filter out those alerts from the user's view.MATERIALS AND METHODS: We identified features (eg, patient and provider characteristics)...

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Liu S, Kawamoto K, Del Fiol G, et al. The potential for leveraging machine learning to filter medication alerts. J Am Med Inform Assoc. 2022;doi: 10.1093/jamia/ocab292.
Liu, S., Kawamoto, K., Del Fiol, G., Weir, C., Malone, D. C., Reese, T. J., Morgan, K., ElHalta, D., & Abdelrahman, S. (2022). The potential for leveraging machine learning to filter medication alerts. Journal of the American Medical Informatics Association : JAMIA, . https://doi.org/10.1093/jamia/ocab292
Liu, Siru, et al. "The potential for leveraging machine learning to filter medication alerts." Journal of the American Medical Informatics Association : JAMIA vol. (2022). doi: https://doi.org/10.1093/jamia/ocab292
Liu S, Kawamoto K, Del Fiol G, Weir C, Malone DC, Reese TJ, Morgan K, ElHalta D, Abdelrahman S. The potential for leveraging machine learning to filter medication alerts. J Am Med Inform Assoc. 2022 Jan 05; doi: 10.1093/jamia/ocab292. Epub 2022 Jan 05. PMID: 34990507.
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Successful Multi-Level HPV Vaccination Intervention at a Rural Healthcare Center in the Era of COVID-19.

Frontiers in digital health

Kepka D, Christini K, McGough E, Wagner A, Del Fiol G, Gibson B, Ayres S, Brandt HM, Mann S, Petrik AF, Coronado GD.
PMID: 34713184
Front Digit Health. 2021 Aug 19;3:719138. doi: 10.3389/fdgth.2021.719138. eCollection 2021.

No abstract available.

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Kepka D, Christini K, McGough E, et al. Successful Multi-Level HPV Vaccination Intervention at a Rural Healthcare Center in the Era of COVID-19. Front Digit Health. 2021;3:719138doi: 10.3389/fdgth.2021.719138.
Kepka, D., Christini, K., McGough, E., Wagner, A., Del Fiol, G., Gibson, B., Ayres, S., Brandt, H. M., Mann, S., Petrik, A. F., & Coronado, G. D. (2021). Successful Multi-Level HPV Vaccination Intervention at a Rural Healthcare Center in the Era of COVID-19. Frontiers in digital health, 3719138. https://doi.org/10.3389/fdgth.2021.719138
Kepka, Deanna, et al. "Successful Multi-Level HPV Vaccination Intervention at a Rural Healthcare Center in the Era of COVID-19." Frontiers in digital health vol. 3 (2021): 719138. doi: https://doi.org/10.3389/fdgth.2021.719138
Kepka D, Christini K, McGough E, Wagner A, Del Fiol G, Gibson B, Ayres S, Brandt HM, Mann S, Petrik AF, Coronado GD. Successful Multi-Level HPV Vaccination Intervention at a Rural Healthcare Center in the Era of COVID-19. Front Digit Health. 2021 Aug 19;3:719138. doi: 10.3389/fdgth.2021.719138. eCollection 2021. PMID: 34713184; PMCID: PMC8521914.
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Residue Cluster Classes: A Unified Protein Representation for Efficient Structural and Functional Classification.

Entropy (Basel, Switzerland)

Fontove F, Del Rio G.
PMID: 33286246
Entropy (Basel). 2020 Apr 20;22(4). doi: 10.3390/e22040472.

Proteins are characterized by their structures and functions, and these two fundamental aspects of proteins are assumed to be related. To model such a relationship, a single representation to model both protein structure and function would be convenient, yet...

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Fontove F, Del Rio G. Residue Cluster Classes: A Unified Protein Representation for Efficient Structural and Functional Classification. Entropy (Basel). 2020;22(4)doi: 10.3390/e22040472.
Fontove, F., & Del Rio, G. (2020). Residue Cluster Classes: A Unified Protein Representation for Efficient Structural and Functional Classification. Entropy (Basel, Switzerland), 22(4), . https://doi.org/10.3390/e22040472
Fontove, Fernando, and Del Rio, Gabriel. "Residue Cluster Classes: A Unified Protein Representation for Efficient Structural and Functional Classification." Entropy (Basel, Switzerland) vol. 22,4 (2020). doi: https://doi.org/10.3390/e22040472
Fontove F, Del Rio G. Residue Cluster Classes: A Unified Protein Representation for Efficient Structural and Functional Classification. Entropy (Basel). 2020 Apr 20;22(4). doi: 10.3390/e22040472. PMID: 33286246; PMCID: PMC7516957.
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An automatic representation of peptides for effective antimicrobial activity classification.

Computational and structural biotechnology journal

Beltran JA, Del Rio G, Brizuela CA.
PMID: 32180904
Comput Struct Biotechnol J. 2020 Feb 26;18:455-463. doi: 10.1016/j.csbj.2020.02.002. eCollection 2020.

Antimicrobial peptides (AMPs) are a promising alternative to small-molecules-based antibiotics. These peptides are part of most living organisms' innate defense system. In order to computationally identify new AMPs within the peptides these organisms produce, an automatic AMP/non-AMP classifier is...

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Beltran JA, Del Rio G, Brizuela CA. An automatic representation of peptides for effective antimicrobial activity classification. Comput Struct Biotechnol J. 2020;18:455-463doi: 10.1016/j.csbj.2020.02.002.
Beltran, J. A., Del Rio, G., & Brizuela, C. A. (2020). An automatic representation of peptides for effective antimicrobial activity classification. Computational and structural biotechnology journal, 18455-463. https://doi.org/10.1016/j.csbj.2020.02.002
Beltran, Jesus A, et al. "An automatic representation of peptides for effective antimicrobial activity classification." Computational and structural biotechnology journal vol. 18 (2020): 455-463. doi: https://doi.org/10.1016/j.csbj.2020.02.002
Beltran JA, Del Rio G, Brizuela CA. An automatic representation of peptides for effective antimicrobial activity classification. Comput Struct Biotechnol J. 2020 Feb 26;18:455-463. doi: 10.1016/j.csbj.2020.02.002. eCollection 2020. PMID: 32180904; PMCID: PMC7063200.
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Temporal Pattern Detection to Predict Adverse Events in Critical Care: Case Study With Acute Kidney Injury.

JMIR medical informatics

Morid MA, Sheng ORL, Del Fiol G, Facelli JC, Bray BE, Abdelrahman S.
PMID: 32181753
JMIR Med Inform. 2020 Mar 17;8(3):e14272. doi: 10.2196/14272.

BACKGROUND: More than 20% of patients admitted to the intensive care unit (ICU) develop an adverse event (AE). No previous study has leveraged patients' data to extract the temporal features using their structural temporal patterns, that is, trends.OBJECTIVE: This...

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Morid MA, Sheng ORL, Del Fiol G, et al. Temporal Pattern Detection to Predict Adverse Events in Critical Care: Case Study With Acute Kidney Injury. JMIR Med Inform. 2020;8(3):e14272doi: 10.2196/14272.
Morid, M. A., Sheng, O. R. L., Del Fiol, G., Facelli, J. C., Bray, B. E., & Abdelrahman, S. (2020). Temporal Pattern Detection to Predict Adverse Events in Critical Care: Case Study With Acute Kidney Injury. JMIR medical informatics, 8(3), e14272. https://doi.org/10.2196/14272
Morid, Mohammad Amin, et al. "Temporal Pattern Detection to Predict Adverse Events in Critical Care: Case Study With Acute Kidney Injury." JMIR medical informatics vol. 8,3 (2020): e14272. doi: https://doi.org/10.2196/14272
Morid MA, Sheng ORL, Del Fiol G, Facelli JC, Bray BE, Abdelrahman S. Temporal Pattern Detection to Predict Adverse Events in Critical Care: Case Study With Acute Kidney Injury. JMIR Med Inform. 2020 Mar 17;8(3):e14272. doi: 10.2196/14272. PMID: 32181753; PMCID: PMC7109618.
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Increasing Complexity in Rule-Based Clinical Decision Support: The Symptom Assessment and Management Intervention.

JMIR medical informatics

Lobach DF, Johns EB, Halpenny B, Saunders TA, Brzozowski J, Del Fiol G, Berry DL, Braun IM, Finn K, Wolfe J, Abrahm JL, Cooley ME.
PMID: 27826132
JMIR Med Inform. 2016 Nov 08;4(4):e36. doi: 10.2196/medinform.5728.

BACKGROUND: Management of uncontrolled symptoms is an important component of quality cancer care. Clinical guidelines are available for optimal symptom management, but are not often integrated into the front lines of care. The use of clinical decision support (CDS)...

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Lobach DF, Johns EB, Halpenny B, et al. Increasing Complexity in Rule-Based Clinical Decision Support: The Symptom Assessment and Management Intervention. JMIR Med Inform. 2016;4(4):e36doi: 10.2196/medinform.5728.
Lobach, D. F., Johns, E. B., Halpenny, B., Saunders, T. A., Brzozowski, J., Del Fiol, G., Berry, D. L., Braun, I. M., Finn, K., Wolfe, J., Abrahm, J. L., & Cooley, M. E. (2016). Increasing Complexity in Rule-Based Clinical Decision Support: The Symptom Assessment and Management Intervention. JMIR medical informatics, 4(4), e36. https://doi.org/10.2196/medinform.5728
Lobach, David F, et al. "Increasing Complexity in Rule-Based Clinical Decision Support: The Symptom Assessment and Management Intervention." JMIR medical informatics vol. 4,4 (2016): e36. doi: https://doi.org/10.2196/medinform.5728
Lobach DF, Johns EB, Halpenny B, Saunders TA, Brzozowski J, Del Fiol G, Berry DL, Braun IM, Finn K, Wolfe J, Abrahm JL, Cooley ME. Increasing Complexity in Rule-Based Clinical Decision Support: The Symptom Assessment and Management Intervention. JMIR Med Inform. 2016 Nov 08;4(4):e36. doi: 10.2196/medinform.5728. PMID: 27826132; PMCID: PMC5120240.
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User interface approaches implemented with automated patient deterioration surveillance tools: protocol for a scoping review.

BMJ open

Wan YJ, Del Fiol G, McFarland MM, Wright MC.
PMID: 35027423
BMJ Open. 2022 Jan 13;12(1):e055525. doi: 10.1136/bmjopen-2021-055525.

INTRODUCTION: Early identification of patients who may suffer from unexpected adverse events (eg, sepsis, sudden cardiac arrest) gives bedside staff valuable lead time to care for these patients appropriately. Consequently, many machine learning algorithms have been developed to predict...

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Wan YJ, Del Fiol G, McFarland MM, et al. User interface approaches implemented with automated patient deterioration surveillance tools: protocol for a scoping review. BMJ Open. 2022;12(1):e055525doi: 10.1136/bmjopen-2021-055525.
Wan, Y. J., Del Fiol, G., McFarland, M. M., & Wright, M. C. (2022). User interface approaches implemented with automated patient deterioration surveillance tools: protocol for a scoping review. BMJ open, 12(1), e055525. https://doi.org/10.1136/bmjopen-2021-055525
Wan, Yik-Ki Jacob, et al. "User interface approaches implemented with automated patient deterioration surveillance tools: protocol for a scoping review." BMJ open vol. 12,1 (2022): e055525. doi: https://doi.org/10.1136/bmjopen-2021-055525
Wan YJ, Del Fiol G, McFarland MM, Wright MC. User interface approaches implemented with automated patient deterioration surveillance tools: protocol for a scoping review. BMJ Open. 2022 Jan 13;12(1):e055525. doi: 10.1136/bmjopen-2021-055525. PMID: 35027423.
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Showing 1 to 12 of 55 entries