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Showing 1 to 4 of 4 entries
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Nanobioengineering and Characterization of a Novel Estrogen Receptor Biosensor.

Sensors (Basel, Switzerland)

Berthier A, Elie-Caille C, Lesniewska E, Delage-Mourroux R, Boireau W.
PMID: 27879944
Sensors (Basel). 2008 Jul 28;8(7):4413-4428. doi: 10.3390/s8074413.

We constructed an original supramolecular assembly on a surface of sensor composed of an innovative combination of an engineered cytochrome b5 and a modified nucleic acid bound to a synthetic lipid hemimembrane. The protein/DNA block, called (PDNA) 2, was...

EZH2 and KDM6B Expressions Are Associated with Specific Epigenetic Signatures during EMT in Non Small Cell Lung Carcinomas.

Cancers

Lachat C, Bruyère D, Etcheverry A, Aubry M, Mosser J, Warda W, Herfs M, Hendrick E, Ferrand C, Borg C, Delage-Mourroux R, Feugeas JP, Guittaut M, Hervouet E, Peixoto P.
PMID: 33291363
Cancers (Basel). 2020 Dec 05;12(12). doi: 10.3390/cancers12123649.

The role of Epigenetics in Epithelial Mesenchymal Transition (EMT) has recently emerged. Two epigenetic enzymes with paradoxical roles have previously been associated to EMT, EZH2 (Enhancer of Zeste 2 Polycomb Repressive Complex 2 (PRC2) Subunit), a lysine methyltranserase able...

Cells

Claude-Taupin A, Fonderflick L, Gauthier T, Mansi L, Pallandre JR, Borg C, Perez V, Monnien F, Algros MP, Vigneron M, Adami P, Delage-Mourroux R, Peixoto P, Herfs M, Boyer-Guittaut M, Hervouet E.
PMID: 30563263
Cells. 2018 Dec 06;7(12). doi: 10.3390/cells7120248.

Early detection and targeted treatments have led to a significant decrease in mortality linked to breast cancer (BC), however, important issues need to be addressed in the future. One of them will be to find new triple negative breast...

GABARAPL1 tumor suppressive function is independent of its conjugation to autophagosomes in MCF-7 breast cancer cells.

Oncotarget

Poillet-Perez L, Jacquet M, Hervouet E, Gauthier T, Fraichard A, Borg C, Pallandre JR, Gonzalez BJ, Ramdani Y, Boyer-Guittaut M, Delage-Mourroux R, Despouy G.
PMID: 28915569
Oncotarget. 2017 Jul 27;8(34):55998-56020. doi: 10.18632/oncotarget.19639. eCollection 2017 Aug 22.

The GABARAPL1 protein belongs to the ATG8 family whose members are involved in autophagy. Our laboratory previously demonstrated that GABARAPL1 associates with autophagic vesicles, regulates autophagic flux and acts as a tumor suppressor protein in breast cancer. In this...

Showing 1 to 4 of 4 entries