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Association study on the DUSP6 gene, an affective disorder candidate gene on 12q23, performed by using fluorescence resonance energy transfer-based melting curve analysis on the LightCycler.

Molecular psychiatry

Toyota T, Watanabe A, Shibuya H, Nankai M, Hattori E, Yamada K, Kurumaji A, Karkera JD, Detera-Wadleigh SD, Yoshikawa T.
PMID: 11035444
Mol Psychiatry. 2000 Sep;5(5):489-494. doi: 10.1038/sj.mp.4000748.

We introduced a new genotyping method, fluorescence resonance energy transfer-based melting curve analysis on the LightCycler, for the analysis of the gene, DUSP6 (dual specificity MAP kinase phosphatase 6), in affective disorder patients. The DUSP6 gene is located on...

Common variations in ALG9 are not associated with bipolar I disorder: a family-based study.

Behavioral and brain functions : BBF

Baysal BE, Willett-Brozick JE, Bacanu SA, Detera-Wadleigh S, Nimgaonkar VL.
PMID: 16859551
Behav Brain Funct. 2006 Jul 21;2:25. doi: 10.1186/1744-9081-2-25.

BACKGROUND: A mannosyltransferase gene (ALG9, DIBD1) at chromosome band 11q23 was previously identified to be disrupted by a balanced chromosomal translocation t(9;11)(p24;q23) co-segregating with bipolar affective disorder in a small family. Inborn ALG9 deficiency (congenital disorders of glycosylation type...

Mutation screening of two candidate genes from 13q32 in families affected with Bipolar disorder: human peptide transporter (SLC15A1) and human glypican5 (GPC5).

BMC genomics

Maheshwari M, Christian SL, Liu C, Badner JA, Detera-Wadleigh S, Gershon ES, Gibbs RA.
PMID: 12392603
BMC Genomics. 2002 Oct 22;3(1):30. doi: 10.1186/1471-2164-3-30. Epub 2002 Oct 22.

BACKGROUND: Multiple candidate regions as sites for Schizophrenia and Bipolar susceptibility genes have been reported, suggesting heterogeneity of susceptibility genes or oligogenic inheritance. Linkage analysis has suggested chromosome 13q32 as one of the regions with evidence of linkage to...

Showing 1 to 3 of 3 entries