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Rombouts FJR, Kusakabe KI, Alexander R, et al. JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate. J Med Chem. 2021;64(19):14175-14191doi: 10.1021/acs.jmedchem.1c00935.
Rombouts, F. J. R., Kusakabe, K. I., Alexander, R., Austin, N., Borghys, H., De Cleyn, M., Dhuyvetter, D., Gijsen, H. J. M., Hrupka, B., Jacobs, T., Jerhaoui, S., Lammens, L., Leclercq, L., Tsubone, K., Ueno, T., Morimoto, K., Einaru, S., Sumiyoshi, H., Van den Bergh, A., Vos, A., Surkyn, M., Teisman, A., & Moechars, D. (2021). JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate. Journal of medicinal chemistry, 64(19), 14175-14191. https://doi.org/10.1021/acs.jmedchem.1c00935
Rombouts, Frederik J R, et al. "JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate." Journal of medicinal chemistry vol. 64,19 (2021): 14175-14191. doi: https://doi.org/10.1021/acs.jmedchem.1c00935
Rombouts FJR, Kusakabe KI, Alexander R, Austin N, Borghys H, De Cleyn M, Dhuyvetter D, Gijsen HJM, Hrupka B, Jacobs T, Jerhaoui S, Lammens L, Leclercq L, Tsubone K, Ueno T, Morimoto K, Einaru S, Sumiyoshi H, Van den Bergh A, Vos A, Surkyn M, Teisman A, Moechars D. JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate. J Med Chem. 2021 Oct 14;64(19):14175-14191. doi: 10.1021/acs.jmedchem.1c00935. Epub 2021 Sep 23. PMID: 34553934.
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