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Showing 1 to 12 of 539 entries
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Micro RNAs in the development of non-alcoholic fatty liver disease.

World journal of hepatology

Gerhard GS, DiStefano JK.
PMID: 25729477
World J Hepatol. 2015 Feb 27;7(2):226-34. doi: 10.4254/wjh.v7.i2.226.

Nonalcoholic fatty liver disease or nonalcoholic fatty liver disease (NAFLD) refers to a group of disorders that arise from the accrual of fat in hepatocytes. Although various factors have been associated with the development of NAFLD, including genetic predisposition...

Point-of-Use Mixing of Influenza H5N1 Vaccine and MF59 Adjuvant for Pandemic Vaccination Preparedness: Antibody Responses and Safety. A Phase 1 Clinical Trial.

Open forum infectious diseases

Mulligan MJ, Bernstein DI, Frey S, Winokur P, Rouphael N, Dickey M, Edupuganti S, Spearman P, Anderson E, Graham I, Noah DL, Mangal B, Kim S, Hill H, Whitaker J, Emery W, Beck A, Stephens K, Hartwell B, Ogilvie M, Rimann N, Osinski E, Destefano E, Gajadhar T, Strudwick A, Pierce K, Lai L, Yue L, Wang D, Ying C, Cline A, Foltz T, Wagner N, Dull G, Pacatte T, Taggart B, Johnson V, Haller L, Looney C, Li S, May M, Myers B, May R, Parker L, Cochran N, Bowen D, Bell M, Scoggins J, Burns A, Stablein C, Wolff M, Jolles B, Leung B, Lambert L, Shorer S, Buchanan W, Murray S, Chang S, Gorman R.
PMID: 25734170
Open Forum Infect Dis. 2014 Nov 18;1(3):ofu102. doi: 10.1093/ofid/ofu102. eCollection 2014 Dec.

BACKGROUND: Avian influenza A/H5N1 has threatened human health for nearly 2 decades. Avian influenza A vaccine without adjuvant is poorly immunogenic. A flexible rapid tactic for mass vaccination will be needed if a pandemic occurs.METHODS: A multicenter, randomized, blinded...

Statistical Ring Catenation under Thermodynamic Control: Should the Jacobson-Stockmayer Cyclization Theory Take into Account Catenane Formation?.

The journal of physical chemistry. B

Di Stefano S, Ercolani G.
PMID: 28045521
J Phys Chem B. 2017 Jan 26;121(3):649-656. doi: 10.1021/acs.jpcb.6b12323. Epub 2017 Jan 12.

An extension of the Jacobson-Stockmayer theory is presented to include the reversible formation of [2]catenanes in a ring-chain system under thermodynamic control. The extended theory is based on the molar catenation constant, measuring the ease of catenation of two...

C-H Bond Oxidation Catalyzed by an Imine-Based Iron Complex: A Mechanistic Insight.

Inorganic chemistry

Olivo G, Nardi M, Vìdal D, Barbieri A, Lapi A, Gómez L, Lanzalunga O, Costas M, Di Stefano S.
PMID: 26457760
Inorg Chem. 2015 Nov 02;54(21):10141-52. doi: 10.1021/acs.inorgchem.5b01500. Epub 2015 Oct 12.

A family of imine-based nonheme iron(II) complexes (LX)2Fe(OTf)2 has been prepared, characterized, and employed as C-H oxidation catalysts. Ligands LX (X = 1, 2, 3, and 4) stand for tridentate imine ligands resulting from spontaneous condensation of 2-pycolyl-amine and...

Evidence-based leadership council - a national collaborative.

Frontiers in public health

Haynes M, Hughes S, Lorig K, Simmons J, Snyder SJ, Steinman L, Wilson N, DiStefano R, Raymond J, FallCreek S, Pelaez MB, Smith D.
PMID: 25964895
Front Public Health. 2015 Apr 27;2:136. doi: 10.3389/fpubh.2014.00136. eCollection 2014.

No abstract available.

Copper(I)-induced amplification of a [2]catenane in a virtual dynamic library of macrocyclic alkenes.

Organic & biomolecular chemistry

Berrocal JA, Nieuwenhuizen MM, Mandolini L, Meijer EW, Di Stefano S.
PMID: 24995844
Org Biomol Chem. 2014 Aug 28;12(32):6167-74. doi: 10.1039/c4ob01009d. Epub 2014 Jul 04.

Olefin cross-metathesis of diluted dichloromethane solutions (≤0.15 M) of the 28-membered macrocyclic alkene C1, featuring a 1,10-phenanthroline moiety in the backbone, as well as of catenand 1, composed of two identical interlocked C1 units, generates families of noninterlocked oligomers...

The Relationship between Older Drivers' Performance on the Driving Observation Schedule (eDOS) and Cognitive Performance.

Annals of advances in automotive medicine. Association for the Advancement of Automotive Medicine. Annual Scientific Conference

Koppel S, Charlton J, Langford J, Vlahodimitrakou Z, Di Stefano M, Macdonald W, Mazer B, Gelinas I, Vrkljan B, Marshall S.
PMID: 24406947
Ann Adv Automot Med. 2013;57:67-76.

RESEARCH QUESTION/OBJECTIVE: The Driving Observation Schedule (eDOS) was developed for use in the Candrive/Ozcandrive five-year prospective study of older drivers to observe the driving behavior of older drivers and monitor changes in driving behaviors over time. The aim of...

Mediterranean circulation perturbations over the last five centuries: Relevance to past Eastern Mediterranean Transient-type events.

Scientific reports

Incarbona A, Martrat B, Mortyn PG, Sprovieri M, Ziveri P, Gogou A, Jordà G, Xoplaki E, Luterbacher J, Langone L, Marino G, Rodríguez-Sanz L, Triantaphyllou M, Di Stefano E, Grimalt JO, Tranchida G, Sprovieri R, Mazzola S.
PMID: 27412622
Sci Rep. 2016 Jul 14;6:29623. doi: 10.1038/srep29623.

The Eastern Mediterranean Transient (EMT) occurred in the Aegean Sea from 1988 to 1995 and is the most significant intermediate-to-deep Mediterranean overturning perturbation reported by instrumental records. The EMT was likely caused by accumulation of high salinity waters in...

Electrospray ion mobility mass spectrometry of positively and negatively charged (1R,2S)-dodecyl(2-hydroxy-1-methyl-2-phenylethyl)dimethylammonium bromide aggregates.

Rapid communications in mass spectrometry : RCM

Indelicato S, Bongiorno D, Ceraulo L, Calabrese V, Piazzese D, Napoli A, Mazzotti F, Avellone G, Di Stefano V, Turco Liveri V.
PMID: 26661990
Rapid Commun Mass Spectrom. 2016 Jan 15;30(1):230-8. doi: 10.1002/rcm.7422.

RATIONALE: Self-assembling processes of surfactants in the gas phase constitute a developing research field of interest since they allow information to be gained on the peculiar structural organization of these aggregates, on their ability to incorporate from small molecules...

Contribution of non-reference alleles in mtDNA of Alzheimer's disease patients.

Annals of clinical and translational neurology

Casoli T, Di Stefano G, Spazzafumo L, Balietti M, Giorgetti B, Giuli C, Postacchini D, Fattoretti P, Conti F.
PMID: 25590040
Ann Clin Transl Neurol. 2014 Apr;1(4):284-9. doi: 10.1002/acn3.42. Epub 2014 Mar 11.

Many observations suggest that mutations of mitochondrial DNA (mtDNA) could be responsible for the neurodegenerative changes of Alzheimer's disease (AD). Here we examined the signal intensity of the four alleles of each mtDNA nucleotide position (np) in whole blood...

Expression of HER-2/neu oncoprotein, DNA-ploidy and S-phase fraction in advanced ovarian cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Scambia G, Benedetti Panici P, Ferrandina G, Battaglia F, Baiocchi G, Di Stefano P, Tinari N, Coronetta F, Piantelli M, Natali P, Iacobelli S, Mancuso S.
PMID: 11578357
Int J Gynecol Cancer. 1993 Sep;3(5):271-278. doi: 10.1046/j.1525-1438.1993.03050271.x.

The immunohistochemical expression of HER-2/neu and cytofluorimetric data were retrospectively analyzed in a group of primary advanced ovarian cancers. Thirty-three out of 94 (35%) cases showed a specific p185/neu immunoreaction. No correlation between p185/neu expression and any of the...

Elusive 6-exo-Hydroxybicyclo[2.2.2]octan-2-ones from the corresponding acetates by methanolysis in the presence of CH(3)ONa/La(OTf)(3).

Organic letters

Di Stefano S, Leonelli F, Garofalo B, Mandolini L, Marini Bettolo R, Migneco LM.
PMID: 12153234
Org Lett. 2002 Aug 08;4(16):2783-5. doi: 10.1021/ol026326p.

[reaction: see text] A series of 6-exo-acetoxybicyclo[2.2.2]octan-2-ones were converted into the corresponding 6-exo-hydroxybicyclo[2.2.2]octan-2-ones by methanolysis in the presence of CH(3)ONa/La(OTf)(3). Under the given conditions, epimerization at C(6) of the latter led in the least favorable cases only to traces...

Showing 1 to 12 of 539 entries