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Fragment Binding to β-Secretase 1 without Catalytic Aspartate Interactions Identified via Orthogonal Screening Approaches.

ACS omega

Rombouts FJR, Alexander R, Cleiren E, De Groot A, Carpentier M, Dijkmans J, Fierens K, Masure S, Moechars D, Palomino-Schätzlein M, Pineda-Lucena A, Trabanco AA, Van Glabbeek D, Vos A, Tresadern G.
PMID: 28626832
ACS Omega. 2017 Feb 28;2(2):685-697. doi: 10.1021/acsomega.6b00482. Epub 2017 Feb 24.

An approach to identify β-secretase 1 (BACE1) fragment binders that do not interact with the catalytic aspartate dyad is presented. A ThermoFluor (thermal shift) and a fluorescence resonance energy transfer enzymatic screen on the soluble domain of BACE1, together...

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Rombouts FJR, Alexander R, Cleiren E, et al. Fragment Binding to β-Secretase 1 without Catalytic Aspartate Interactions Identified via Orthogonal Screening Approaches. ACS Omega. 2017;2(2):685-697doi: 10.1021/acsomega.6b00482.
Rombouts, F. J. R., Alexander, R., Cleiren, E., De Groot, A., Carpentier, M., Dijkmans, J., Fierens, K., Masure, S., Moechars, D., Palomino-Schätzlein, M., Pineda-Lucena, A., Trabanco, A. A., Van Glabbeek, D., Vos, A., & Tresadern, G. (2017). Fragment Binding to β-Secretase 1 without Catalytic Aspartate Interactions Identified via Orthogonal Screening Approaches. ACS omega, 2(2), 685-697. https://doi.org/10.1021/acsomega.6b00482
Rombouts, Frederik J R, et al. "Fragment Binding to β-Secretase 1 without Catalytic Aspartate Interactions Identified via Orthogonal Screening Approaches." ACS omega vol. 2,2 (2017): 685-697. doi: https://doi.org/10.1021/acsomega.6b00482
Rombouts FJR, Alexander R, Cleiren E, De Groot A, Carpentier M, Dijkmans J, Fierens K, Masure S, Moechars D, Palomino-Schätzlein M, Pineda-Lucena A, Trabanco AA, Van Glabbeek D, Vos A, Tresadern G. Fragment Binding to β-Secretase 1 without Catalytic Aspartate Interactions Identified via Orthogonal Screening Approaches. ACS Omega. 2017 Feb 28;2(2):685-697. doi: 10.1021/acsomega.6b00482. Epub 2017 Feb 24. PMID: 28626832; PMCID: PMC5472370.
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Traffic model with an absorbing-state phase transition.

Physical review. E

Iannini ML, Dickman R.
PMID: 28297966
Phys Rev E. 2017 Feb;95(2):022106. doi: 10.1103/PhysRevE.95.022106. Epub 2017 Feb 06.

We consider a modified Nagel-Schreckenberg (NS) model in which drivers do not decelerate if their speed is smaller than the headway (number of empty sites to the car ahead). (In the original NS model, such a reduction in speed...

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Iannini ML, Dickman R. Traffic model with an absorbing-state phase transition. Phys Rev E. 2017;95(2):022106doi: 10.1103/PhysRevE.95.022106.
Iannini, M. L., & Dickman, R. (2017). Traffic model with an absorbing-state phase transition. Physical review. E, 95(2), 022106. https://doi.org/10.1103/PhysRevE.95.022106
Iannini, M L L, and Dickman, Ronald. "Traffic model with an absorbing-state phase transition." Physical review. E vol. 95,2 (2017): 022106. doi: https://doi.org/10.1103/PhysRevE.95.022106
Iannini ML, Dickman R. Traffic model with an absorbing-state phase transition. Phys Rev E. 2017 Feb;95(2):022106. doi: 10.1103/PhysRevE.95.022106. Epub 2017 Feb 06. PMID: 28297966.
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Correction: Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950)

Haanstra KG, Dijkman K, Bashir N, Bauer J, Mary C, Poirier N, Baker P, Scobie L, 't Hart BA, Vanhove B.
PMID: 26138639
J Immunol. 2015 Jul 15;195(2):749. doi: 10.4049/jimmunol.1501150.

No abstract available.

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Haanstra KG, Dijkman K, Bashir N, et al. Correction: Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis. J Immunol. 2015;195(2):749doi: 10.4049/jimmunol.1501150.
Haanstra, K. G., Dijkman, K., Bashir, N., Bauer, J., Mary, C., Poirier, N., Baker, P., Scobie, L., 't Hart, B. A., & Vanhove, B. (2015). Correction: Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950), 195(2), 749. https://doi.org/10.4049/jimmunol.1501150
Haanstra, Krista G, et al. "Correction: Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis." Journal of immunology (Baltimore, Md. : 1950) vol. 195,2 (2015): 749. doi: https://doi.org/10.4049/jimmunol.1501150
Haanstra KG, Dijkman K, Bashir N, Bauer J, Mary C, Poirier N, Baker P, Scobie L, 't Hart BA, Vanhove B. Correction: Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis. J Immunol. 2015 Jul 15;195(2):749. doi: 10.4049/jimmunol.1501150. PMID: 26138639.
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Nonuniversality in the pair contact process with diffusion.

Physical review. E, Statistical, nonlinear, and soft matter physics

Dickman R, De Menezes MA.
PMID: 12443242
Phys Rev E Stat Nonlin Soft Matter Phys. 2002 Oct;66(4):045101. doi: 10.1103/PhysRevE.66.045101. Epub 2002 Oct 09.

We study the static and dynamic behavior of the one dimensional pair contact process with diffusion. Several critical exponents are found to vary with the diffusion rate, while the order-parameter moment ratio m=rho(2);/rho;(2) grows logarithmically with system size. The...

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Dickman R, De Menezes MA. Nonuniversality in the pair contact process with diffusion. Phys Rev E Stat Nonlin Soft Matter Phys. 2002;66(4):045101doi: 10.1103/PhysRevE.66.045101.
Dickman, R., & De Menezes, M. A. (2002). Nonuniversality in the pair contact process with diffusion. Physical review. E, Statistical, nonlinear, and soft matter physics, 66(4), 045101. https://doi.org/10.1103/PhysRevE.66.045101
Dickman, Ronald, and De Menezes, Marcio Argollo Ferreira. "Nonuniversality in the pair contact process with diffusion." Physical review. E, Statistical, nonlinear, and soft matter physics vol. 66,4 (2002): 045101. doi: https://doi.org/10.1103/PhysRevE.66.045101
Dickman R, De Menezes MA. Nonuniversality in the pair contact process with diffusion. Phys Rev E Stat Nonlin Soft Matter Phys. 2002 Oct;66(4):045101. doi: 10.1103/PhysRevE.66.045101. Epub 2002 Oct 09. PMID: 12443242.
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Colloids in a periodic potential: driven lattice gas in continuous space.

Physical review. E, Statistical, nonlinear, and soft matter physics

Potiguar FQ, Dickman R.
PMID: 17930195
Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Sep;76(3):031103. doi: 10.1103/PhysRevE.76.031103. Epub 2007 Sep 07.

Motivated by recent studies of colloidal particles in optical-tweezer arrays, we study a two-dimensional model of a colloidal suspension in a periodic potential. The particles tend to stay near potential minima, approximating a lattice gas. The interparticle interaction, a...

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Potiguar FQ, Dickman R. Colloids in a periodic potential: driven lattice gas in continuous space. Phys Rev E Stat Nonlin Soft Matter Phys. 2007;76(3):031103doi: 10.1103/PhysRevE.76.031103.
Potiguar, F. Q., & Dickman, R. (2007). Colloids in a periodic potential: driven lattice gas in continuous space. Physical review. E, Statistical, nonlinear, and soft matter physics, 76(3), 031103. https://doi.org/10.1103/PhysRevE.76.031103
Potiguar, Fabricio Q, and Dickman, Ronald. "Colloids in a periodic potential: driven lattice gas in continuous space." Physical review. E, Statistical, nonlinear, and soft matter physics vol. 76,3 (2007): 031103. doi: https://doi.org/10.1103/PhysRevE.76.031103
Potiguar FQ, Dickman R. Colloids in a periodic potential: driven lattice gas in continuous space. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Sep;76(3):031103. doi: 10.1103/PhysRevE.76.031103. Epub 2007 Sep 07. PMID: 17930195.
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[Newly graduated veterinarians].

Tijdschrift voor diergeneeskunde

Dijkman H.
PMID: 17263025
Tijdschr Diergeneeskd. 2006 Nov 15;131(22):848.

No abstract available.

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Dijkman H. Pas afgestudeerde dierenartsen. [Newly graduated veterinarians]. Tijdschr Diergeneeskd. 2006;131(22):848
Dijkman, H. (2006). Pas afgestudeerde dierenartsen. [Newly graduated veterinarians]. Tijdschrift voor diergeneeskunde, 131(22), 848.
Dijkman, Henry. "Pas afgestudeerde dierenartsen." [Newly graduated veterinarians]. Tijdschrift voor diergeneeskunde vol. 131,22 (2006): 848.
Dijkman H. Pas afgestudeerde dierenartsen. [Newly graduated veterinarians]. Tijdschr Diergeneeskd. 2006 Nov 15;131(22):848. Dutch. PMID: 17263025.
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Asymmetric exclusion process in a system of interacting Brownian particles.

Physical review. E, Statistical, nonlinear, and soft matter physics

Eduardo de Oliveira Rodrigues J, Dickman R.
PMID: 20866379
Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Jun;81(6):061108. doi: 10.1103/PhysRevE.81.061108. Epub 2010 Jun 04.

We study a continuous-space version of the totally asymmetric simple exclusion process (TASEP), consisting of interacting Brownian particles subject to a driving force in a periodic array of potential wells. Particles are inserted into the leftmost well at rate...

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Eduardo de Oliveira Rodrigues J, Dickman R. Asymmetric exclusion process in a system of interacting Brownian particles. Phys Rev E Stat Nonlin Soft Matter Phys. 2010;81(6):061108doi: 10.1103/PhysRevE.81.061108.
Eduardo de Oliveira Rodrigues, J., & Dickman, R. (2010). Asymmetric exclusion process in a system of interacting Brownian particles. Physical review. E, Statistical, nonlinear, and soft matter physics, 81(6), 061108. https://doi.org/10.1103/PhysRevE.81.061108
Eduardo de Oliveira Rodrigues, José, and Dickman, Ronald. "Asymmetric exclusion process in a system of interacting Brownian particles." Physical review. E, Statistical, nonlinear, and soft matter physics vol. 81,6 (2010): 061108. doi: https://doi.org/10.1103/PhysRevE.81.061108
Eduardo de Oliveira Rodrigues J, Dickman R. Asymmetric exclusion process in a system of interacting Brownian particles. Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Jun;81(6):061108. doi: 10.1103/PhysRevE.81.061108. Epub 2010 Jun 04. PMID: 20866379.
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Herbivory induces systemic production of plant volatiles that attract predators of the herbivore: Extraction of endogenous elicitor.

Journal of chemical ecology

Dicke M, Van Baarlen P, Wessels R, Dijkman H.
PMID: 24248958
J Chem Ecol. 1993 Mar;19(3):581-99. doi: 10.1007/BF00994327.

It was previously shown that in response to infestation by spider mites (Tetranychus urticae), lima bean plants produce a volatile herbivoreinduced synomone that attracts phytoseiid mites (Phytoseiulus persimilis) that are predators of the spider mites. The production of predator-attracting...

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Dicke M, Van Baarlen P, Wessels R, et al. Herbivory induces systemic production of plant volatiles that attract predators of the herbivore: Extraction of endogenous elicitor. J Chem Ecol. 1993;19(3):581-99doi: 10.1007/BF00994327.
Dicke, M., Van Baarlen, P., Wessels, R., & Dijkman, H. (1993). Herbivory induces systemic production of plant volatiles that attract predators of the herbivore: Extraction of endogenous elicitor. Journal of chemical ecology, 19(3), 581-99. https://doi.org/10.1007/BF00994327
Dicke, M, et al. "Herbivory induces systemic production of plant volatiles that attract predators of the herbivore: Extraction of endogenous elicitor." Journal of chemical ecology vol. 19,3 (1993): 581-99. doi: https://doi.org/10.1007/BF00994327
Dicke M, Van Baarlen P, Wessels R, Dijkman H. Herbivory induces systemic production of plant volatiles that attract predators of the herbivore: Extraction of endogenous elicitor. J Chem Ecol. 1993 Mar;19(3):581-99. doi: 10.1007/BF00994327. PMID: 24248958.
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Comparison of clinical characteristics of patients with gastroesophageal reflux disease who failed proton pump inhibitor therapy versus those who fully responded.

Journal of neurogastroenterology and motility

Dickman R, Boaz M, Aizic S, Beniashvili Z, Fass R, Niv Y.
PMID: 22148108
J Neurogastroenterol Motil. 2011 Oct;17(4):387-94. doi: 10.5056/jnm.2011.17.4.387. Epub 2011 Oct 31.

BACKGROUND/AIMS: Refractory gastroesophageal reflux disease (GERD) is very common, affecting up to 40% of the patients receiving proton pump inhibitor (PPI) therapy. However, there is not much information about the clinical characteristics of these patients. The aim of the...

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Dickman R, Boaz M, Aizic S, et al. Comparison of clinical characteristics of patients with gastroesophageal reflux disease who failed proton pump inhibitor therapy versus those who fully responded. J Neurogastroenterol Motil. 2011;17(4):387-94doi: 10.5056/jnm.2011.17.4.387.
Dickman, R., Boaz, M., Aizic, S., Beniashvili, Z., Fass, R., & Niv, Y. (2011). Comparison of clinical characteristics of patients with gastroesophageal reflux disease who failed proton pump inhibitor therapy versus those who fully responded. Journal of neurogastroenterology and motility, 17(4), 387-94. https://doi.org/10.5056/jnm.2011.17.4.387
Dickman, Ram, et al. "Comparison of clinical characteristics of patients with gastroesophageal reflux disease who failed proton pump inhibitor therapy versus those who fully responded." Journal of neurogastroenterology and motility vol. 17,4 (2011): 387-94. doi: https://doi.org/10.5056/jnm.2011.17.4.387
Dickman R, Boaz M, Aizic S, Beniashvili Z, Fass R, Niv Y. Comparison of clinical characteristics of patients with gastroesophageal reflux disease who failed proton pump inhibitor therapy versus those who fully responded. J Neurogastroenterol Motil. 2011 Oct;17(4):387-94. doi: 10.5056/jnm.2011.17.4.387. Epub 2011 Oct 31. PMID: 22148108; PMCID: PMC3228979.
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Wigner-distribution- and Green's-function approach to quantum corrections and implications for the melting temperature of two-dimensional Wigner crystals.

Physical review. B, Condensed matter

Dickman R, O'Connell RF.
PMID: 9936689
Phys Rev B Condens Matter. 1985 Jul 01;32(1):471-473. doi: 10.1103/physrevb.32.471.

No abstract available.

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Dickman R, O'Connell RF. Wigner-distribution- and Green's-function approach to quantum corrections and implications for the melting temperature of two-dimensional Wigner crystals. Phys Rev B Condens Matter. 1985;32(1):471-473doi: 10.1103/physrevb.32.471.
Dickman, R., & O'Connell, R. F. (1985). Wigner-distribution- and Green's-function approach to quantum corrections and implications for the melting temperature of two-dimensional Wigner crystals. Physical review. B, Condensed matter, 32(1), 471-473. https://doi.org/10.1103/physrevb.32.471
Dickman, and O'Connell. "Wigner-distribution- and Green's-function approach to quantum corrections and implications for the melting temperature of two-dimensional Wigner crystals." Physical review. B, Condensed matter vol. 32,1 (1985): 471-473. doi: https://doi.org/10.1103/physrevb.32.471
Dickman R, O'Connell RF. Wigner-distribution- and Green's-function approach to quantum corrections and implications for the melting temperature of two-dimensional Wigner crystals. Phys Rev B Condens Matter. 1985 Jul 01;32(1):471-473. doi: 10.1103/physrevb.32.471. PMID: 9936689.
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Integrating the Rabinowitz rarity framework with a National Plant Inventory in South Korea.

Ecology and evolution

Choe H, Thorne JH, Hijmans R, Seo C.
PMID: 30805165
Ecol Evol. 2019 Jan 13;9(3):1353-1363. doi: 10.1002/ece3.4851. eCollection 2019 Feb.

Increasingly large presence-only survey datasets are becoming available for use in conservation assessments. Potentially, these records could be used to determine spatial patterns of plant species rarity and endemism. We test the integration of a large South Korean species...

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Choe H, Thorne JH, Hijmans R, et al. Integrating the Rabinowitz rarity framework with a National Plant Inventory in South Korea. Ecol Evol. 2019;9(3):1353-1363doi: 10.1002/ece3.4851.
Choe, H., Thorne, J. H., Hijmans, R., & Seo, C. (2019). Integrating the Rabinowitz rarity framework with a National Plant Inventory in South Korea. Ecology and evolution, 9(3), 1353-1363. https://doi.org/10.1002/ece3.4851
Choe, Hyeyeong, et al. "Integrating the Rabinowitz rarity framework with a National Plant Inventory in South Korea." Ecology and evolution vol. 9,3 (2019): 1353-1363. doi: https://doi.org/10.1002/ece3.4851
Choe H, Thorne JH, Hijmans R, Seo C. Integrating the Rabinowitz rarity framework with a National Plant Inventory in South Korea. Ecol Evol. 2019 Jan 13;9(3):1353-1363. doi: 10.1002/ece3.4851. eCollection 2019 Feb. PMID: 30805165; PMCID: PMC6374650.
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Comparison of strategies and goals for treatment of chronic constipation among gastroenterologists and general practitioners.

Annals of gastroenterology

Carter D, Bardan E, Dickman R.
PMID: 29333069
Ann Gastroenterol. 2018 Jan-Feb;31(1):71-76. doi: 10.20524/aog.2017.0214. Epub 2017 Nov 16.

BACKGROUND: Although guidelines have been published for the treatment of chronic constipation, little is known about the actual treatment strategies, the definitions of drug efficacy, the parameters for drug selection, and the conceived limitations of the available treatments. The...

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Carter D, Bardan E, Dickman R. Comparison of strategies and goals for treatment of chronic constipation among gastroenterologists and general practitioners. Ann Gastroenterol. 2017;31(1):71-76doi: 10.20524/aog.2017.0214.
Carter, D., Bardan, E., & Dickman, R. (2018). Comparison of strategies and goals for treatment of chronic constipation among gastroenterologists and general practitioners. Annals of gastroenterology, 31(1), 71-76. https://doi.org/10.20524/aog.2017.0214
Carter, Dan, et al. "Comparison of strategies and goals for treatment of chronic constipation among gastroenterologists and general practitioners." Annals of gastroenterology vol. 31,1 (2018): 71-76. doi: https://doi.org/10.20524/aog.2017.0214
Carter D, Bardan E, Dickman R. Comparison of strategies and goals for treatment of chronic constipation among gastroenterologists and general practitioners. Ann Gastroenterol. 2018 Jan-Feb;31(1):71-76. doi: 10.20524/aog.2017.0214. Epub 2017 Nov 16. PMID: 29333069; PMCID: PMC5760770.
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Showing 1 to 12 of 178 entries