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Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome.

Frontiers in immunology

O'Connell AE, Volpi S, Dobbs K, Fiorini C, Tsitsikov E, de Boer H, Barlan IB, Despotovic JM, Espinosa-Rosales FJ, Hanson IC, Kanariou MG, Martínez-Beckerat R, Mayorga-Sirera A, Mejia-Carvajal C, Radwan N, Weiss AR, Pai SY, Lee YN, Notarangelo LD.
PMID: 25101082
Front Immunol. 2014 Jul 18;5:340. doi: 10.3389/fimmu.2014.00340. eCollection 2014.

The Wiskott-Aldrich syndrome (WAS) is due to mutations of the WAS gene encoding for the cytoskeletal WAS protein, leading to abnormal downstream signaling from the T cell and B cell antigen receptors (TCR and BCR). We hypothesized that the...

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O'Connell AE, Volpi S, Dobbs K, et al. Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome. Front Immunol. 2014;5:340doi: 10.3389/fimmu.2014.00340.
O'Connell, A. E., Volpi, S., Dobbs, K., Fiorini, C., Tsitsikov, E., de Boer, H., Barlan, I. B., Despotovic, J. M., Espinosa-Rosales, F. J., Hanson, I. C., Kanariou, M. G., Martínez-Beckerat, R., Mayorga-Sirera, A., Mejia-Carvajal, C., Radwan, N., Weiss, A. R., Pai, S. Y., Lee, Y. N., & Notarangelo, L. D. (2014). Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome. Frontiers in immunology, 5340. https://doi.org/10.3389/fimmu.2014.00340
O'Connell, Amy E, et al. "Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome." Frontiers in immunology vol. 5 (2014): 340. doi: https://doi.org/10.3389/fimmu.2014.00340
O'Connell AE, Volpi S, Dobbs K, Fiorini C, Tsitsikov E, de Boer H, Barlan IB, Despotovic JM, Espinosa-Rosales FJ, Hanson IC, Kanariou MG, Martínez-Beckerat R, Mayorga-Sirera A, Mejia-Carvajal C, Radwan N, Weiss AR, Pai SY, Lee YN, Notarangelo LD. Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome. Front Immunol. 2014 Jul 18;5:340. doi: 10.3389/fimmu.2014.00340. eCollection 2014. PMID: 25101082; PMCID: PMC4102881.
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Computational Characterization of Metal Binding Groups for Metalloenzyme Inhibitors.

Journal of chemical theory and computation

Dobbs KD, Rinehart AM, Howard MH, Zheng YJ, Kleier DA.
PMID: 26633058
J Chem Theory Comput. 2006 Jul;2(4):990-6. doi: 10.1021/ct050192u.

The mode of action of many pest or disease control agents involves inhibition of some metalloenzyme that is essential for the survival of the target organism. These inhibitors typically consist of a functional group that is capable of a...

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Dobbs KD, Rinehart AM, Howard MH, et al. Computational Characterization of Metal Binding Groups for Metalloenzyme Inhibitors. J Chem Theory Comput. 2006;2(4):990-6doi: 10.1021/ct050192u.
Dobbs, K. D., Rinehart, A. M., Howard, M. H., Zheng, Y. J., & Kleier, D. A. (2006). Computational Characterization of Metal Binding Groups for Metalloenzyme Inhibitors. Journal of chemical theory and computation, 2(4), 990-6. https://doi.org/10.1021/ct050192u
Dobbs, Kerwin D, et al. "Computational Characterization of Metal Binding Groups for Metalloenzyme Inhibitors." Journal of chemical theory and computation vol. 2,4 (2006): 990-6. doi: https://doi.org/10.1021/ct050192u
Dobbs KD, Rinehart AM, Howard MH, Zheng YJ, Kleier DA. Computational Characterization of Metal Binding Groups for Metalloenzyme Inhibitors. J Chem Theory Comput. 2006 Jul;2(4):990-6. doi: 10.1021/ct050192u. PMID: 26633058.
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Geriatric core competencies for family medicine curriculum and enhanced skills: care of elderly.

Canadian geriatrics journal : CGJ

Charles L, Triscott JA, Dobbs BM, McKay R.
PMID: 24883163
Can Geriatr J. 2014 Jun 03;17(2):53-62. doi: 10.5770/cgj.17.95. eCollection 2014 Jun.

BACKGROUND: There is a growing mandate for Family Medicine residency programs to directly assess residents' clinical competence in Care of the Elderly (COE). The objectives of this paper are to describe the development and implementation of incremental core competencies...

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Charles L, Triscott JA, Dobbs BM, et al. Geriatric core competencies for family medicine curriculum and enhanced skills: care of elderly. Can Geriatr J. 2014;17(2):53-62doi: 10.5770/cgj.17.95.
Charles, L., Triscott, J. A., Dobbs, B. M., & McKay, R. (2014). Geriatric core competencies for family medicine curriculum and enhanced skills: care of elderly. Canadian geriatrics journal : CGJ, 17(2), 53-62. https://doi.org/10.5770/cgj.17.95
Charles, Lesley, et al. "Geriatric core competencies for family medicine curriculum and enhanced skills: care of elderly." Canadian geriatrics journal : CGJ vol. 17,2 (2014): 53-62. doi: https://doi.org/10.5770/cgj.17.95
Charles L, Triscott JA, Dobbs BM, McKay R. Geriatric core competencies for family medicine curriculum and enhanced skills: care of elderly. Can Geriatr J. 2014 Jun 03;17(2):53-62. doi: 10.5770/cgj.17.95. eCollection 2014 Jun. PMID: 24883163; PMCID: PMC4038536.
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Capillary-wave effects at critical wetting in type-I superconductors.

Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics

Dobbs HT, Blossey R.
PMID: 11088347
Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 2000 Jun;61(6):R6049-51. doi: 10.1103/physreve.61.r6049.

We discuss the effect of fluctuations of the superconductor-normal (SC/N) interface on the (short-range) critical wetting transition in type-I superconductors. Functional renormalization of a standard effective interface Hamiltonian shows that the fluctuation regimes found for short-range critical wetting in...

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Dobbs HT, Blossey R. Capillary-wave effects at critical wetting in type-I superconductors. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 2000;61(6):R6049-51doi: 10.1103/physreve.61.r6049.
Dobbs, H. T., & Blossey, R. (2000). Capillary-wave effects at critical wetting in type-I superconductors. Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics, 61(6), R6049-51. https://doi.org/10.1103/physreve.61.r6049
Dobbs, and Blossey. "Capillary-wave effects at critical wetting in type-I superconductors." Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics vol. 61,6 (2000): R6049-51. doi: https://doi.org/10.1103/physreve.61.r6049
Dobbs HT, Blossey R. Capillary-wave effects at critical wetting in type-I superconductors. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 2000 Jun;61(6):R6049-51. doi: 10.1103/physreve.61.r6049. PMID: 11088347.
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A Versatile and High-Yield Route to Active and Well-Defined Catalysts.

Angewandte Chemie (International ed. in English)

Wiles JA, Bergens SH, Vanhessche KP, Dobbs DA, Rautenstrauch V.
PMID: 11353464
Angew Chem Int Ed Engl. 2001 May 04;40(9):1573. doi: 10.1002/1521-3773(20010504)40:9<1573::aid-anie15731>3.3.co;2-a.

No abstract available.

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Wiles JA, Bergens SH, Vanhessche KP, et al. A Versatile and High-Yield Route to Active and Well-Defined Catalysts. Angew Chem Int Ed Engl. 2001;40(9):1573doi: 10.1002/1521-3773(20010504)40:9<1573::aid-anie15731>3.3.co;2-a.
Wiles, J. A., Bergens, S. H., Vanhessche, K. P., Dobbs, D. A., & Rautenstrauch, V. (2001). A Versatile and High-Yield Route to Active and Well-Defined Catalysts. Angewandte Chemie (International ed. in English), 40(9), 1573. https://doi.org/10.1002/1521-3773(20010504)40:9<1573::aid-anie15731>3.3.co;2-a
Wiles, Jason A., et al. "A Versatile and High-Yield Route to Active and Well-Defined Catalysts." Angewandte Chemie (International ed. in English) vol. 40,9 (2001): 1573. doi: https://doi.org/10.1002/1521-3773(20010504)40:9<1573::aid-anie15731>3.3.co;2-a
Wiles JA, Bergens SH, Vanhessche KP, Dobbs DA, Rautenstrauch V. A Versatile and High-Yield Route to Active and Well-Defined Catalysts. Angew Chem Int Ed Engl. 2001 May 04;40(9):1573. doi: 10.1002/1521-3773(20010504)40:9<1573::aid-anie15731>3.3.co;2-a. PMID: 11353464.
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Evaluation and management of the driver with dementia.

The neurologist

Dobbs BM, Carr DB, Morris JC.
PMID: 12803692
Neurologist. 2002 Mar;8(2):61-70. doi: 10.1097/00127893-200203000-00001.

BACKGROUND: The number of older adult drivers with dementia is expected to increase over the next few decades. This increase raises public and personal safety concerns given the higher crash rates of drivers with a dementing illness. However, the...

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Dobbs BM, Carr DB, Morris JC. Evaluation and management of the driver with dementia. Neurologist. 2002;8(2):61-70doi: 10.1097/00127893-200203000-00001.
Dobbs, B. M., Carr, D. B., & Morris, J. C. (2002). Evaluation and management of the driver with dementia. The neurologist, 8(2), 61-70. https://doi.org/10.1097/00127893-200203000-00001
Dobbs, Bonnie M, et al. "Evaluation and management of the driver with dementia." The neurologist vol. 8,2 (2002): 61-70. doi: https://doi.org/10.1097/00127893-200203000-00001
Dobbs BM, Carr DB, Morris JC. Evaluation and management of the driver with dementia. Neurologist. 2002 Mar;8(2):61-70. doi: 10.1097/00127893-200203000-00001. PMID: 12803692.
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Ambiguities in the scientific revolution: occult and scientific mentalities in the renaissance.

Science (New York, N.Y.)

Dobbs BJ.
PMID: 17770985
Science. 1984 Dec 07;226(4679):1185-6. doi: 10.1126/science.226.4679.1185.

No abstract available.

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Dobbs BJ. Ambiguities in the scientific revolution: occult and scientific mentalities in the renaissance. Science. 1984;226(4679):1185-6doi: 10.1126/science.226.4679.1185.
Dobbs, B. J. (1984). Ambiguities in the scientific revolution: occult and scientific mentalities in the renaissance. Science (New York, N.Y.), 226(4679), 1185-6. https://doi.org/10.1126/science.226.4679.1185
Dobbs, B J. "Ambiguities in the scientific revolution: occult and scientific mentalities in the renaissance." Science (New York, N.Y.) vol. 226,4679 (1984): 1185-6. doi: https://doi.org/10.1126/science.226.4679.1185
Dobbs BJ. Ambiguities in the scientific revolution: occult and scientific mentalities in the renaissance. Science. 1984 Dec 07;226(4679):1185-6. doi: 10.1126/science.226.4679.1185. PMID: 17770985.
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2,6-Bis[2-(4-pentylphenyl)vinyl]anthracene: a stable and high charge mobility organic semiconductor with densely packed crystal structure.

Journal of the American Chemical Society

Meng H, Sun F, Goldfinger MB, Gao F, Londono DJ, Marshal WJ, Blackman GS, Dobbs KD, Keys DE.
PMID: 16848445
J Am Chem Soc. 2006 Jul 26;128(29):9304-5. doi: 10.1021/ja062683+.

The development of new organic semiconductors with improved electrical performance and enhanced environmental stability is the focus of considerable research activity. This paper presents the design, synthesis, optical and electrochemical characterization, crystal packing, modeling and thin film morphology, and...

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Meng H, Sun F, Goldfinger MB, et al. 2,6-Bis[2-(4-pentylphenyl)vinyl]anthracene: a stable and high charge mobility organic semiconductor with densely packed crystal structure. J Am Chem Soc. 2006;128(29):9304-5doi: 10.1021/ja062683+.
Meng, H., Sun, F., Goldfinger, M. B., Gao, F., Londono, D. J., Marshal, W. J., Blackman, G. S., Dobbs, K. D., & Keys, D. E. (2006). 2,6-Bis[2-(4-pentylphenyl)vinyl]anthracene: a stable and high charge mobility organic semiconductor with densely packed crystal structure. Journal of the American Chemical Society, 128(29), 9304-5. https://doi.org/10.1021/ja062683+
Meng, Hong, et al. "2,6-Bis[2-(4-pentylphenyl)vinyl]anthracene: a stable and high charge mobility organic semiconductor with densely packed crystal structure." Journal of the American Chemical Society vol. 128,29 (2006): 9304-5. doi: https://doi.org/10.1021/ja062683+
Meng H, Sun F, Goldfinger MB, Gao F, Londono DJ, Marshal WJ, Blackman GS, Dobbs KD, Keys DE. 2,6-Bis[2-(4-pentylphenyl)vinyl]anthracene: a stable and high charge mobility organic semiconductor with densely packed crystal structure. J Am Chem Soc. 2006 Jul 26;128(29):9304-5. doi: 10.1021/ja062683+. PMID: 16848445.
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Hyperbaric oxygen for carbon monoxide poisoning.

The Western journal of medicine

Kizer KW, Kram JA, Dobbs LG, Herskowitz F.
PMID: 18749037
West J Med. 1982 Feb;136(2):163-4.

No abstract available.

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Kizer KW, Kram JA, Dobbs LG, et al. Hyperbaric oxygen for carbon monoxide poisoning. West J Med. 1982;136(2):163-4
Kizer, K. W., Kram, J. A., Dobbs, L. G., & Herskowitz, F. (1982). Hyperbaric oxygen for carbon monoxide poisoning. The Western journal of medicine, 136(2), 163-4.
Kizer, K W, et al. "Hyperbaric oxygen for carbon monoxide poisoning." The Western journal of medicine vol. 136,2 (1982): 163-4.
Kizer KW, Kram JA, Dobbs LG, Herskowitz F. Hyperbaric oxygen for carbon monoxide poisoning. West J Med. 1982 Feb;136(2):163-4. PMID: 18749037; PMCID: PMC1273563.
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How large a training set is needed to develop a classifier for microarray data?.

Clinical cancer research : an official journal of the American Association for Cancer Research

Dobbin KK, Zhao Y, Simon RM.
PMID: 18172259
Clin Cancer Res. 2008 Jan 01;14(1):108-14. doi: 10.1158/1078-0432.CCR-07-0443.

PURPOSE: A common goal of gene expression microarray studies is the development of a classifier that can be used to divide patients into groups with different prognoses, or with different expected responses to a therapy. These types of classifiers...

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Dobbin KK, Zhao Y, Simon RM. How large a training set is needed to develop a classifier for microarray data?. Clin Cancer Res. 2008;14(1):108-14doi: 10.1158/1078-0432.CCR-07-0443.
Dobbin, K. K., Zhao, Y., & Simon, R. M. (2008). How large a training set is needed to develop a classifier for microarray data?. Clinical cancer research : an official journal of the American Association for Cancer Research, 14(1), 108-14. https://doi.org/10.1158/1078-0432.CCR-07-0443
Dobbin, Kevin K, et al. "How large a training set is needed to develop a classifier for microarray data?." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 14,1 (2008): 108-14. doi: https://doi.org/10.1158/1078-0432.CCR-07-0443
Dobbin KK, Zhao Y, Simon RM. How large a training set is needed to develop a classifier for microarray data?. Clin Cancer Res. 2008 Jan 01;14(1):108-14. doi: 10.1158/1078-0432.CCR-07-0443. PMID: 18172259.
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Use of the Ponseti method for recurrent clubfoot following posteromedial release.

Indian journal of orthopaedics

Garg S, Dobbs MB.
PMID: 19823658
Indian J Orthop. 2008 Jan;42(1):68-72. doi: 10.4103/0019-5413.38584.

BACKGROUND: A child with recurrent or incompletely corrected clubfoot after previous extensive soft tissue release is treated frequently with revision surgery. This leads to further scarring, pain and limitations in range of motion. We have utilized the Ponseti method...

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Garg S, Dobbs MB. Use of the Ponseti method for recurrent clubfoot following posteromedial release. Indian J Orthop. 2008;42(1):68-72doi: 10.4103/0019-5413.38584.
Garg, S., & Dobbs, M. B. (2008). Use of the Ponseti method for recurrent clubfoot following posteromedial release. Indian journal of orthopaedics, 42(1), 68-72. https://doi.org/10.4103/0019-5413.38584
Garg, Sumeet, and Dobbs, Matthew B. "Use of the Ponseti method for recurrent clubfoot following posteromedial release." Indian journal of orthopaedics vol. 42,1 (2008): 68-72. doi: https://doi.org/10.4103/0019-5413.38584
Garg S, Dobbs MB. Use of the Ponseti method for recurrent clubfoot following posteromedial release. Indian J Orthop. 2008 Jan;42(1):68-72. doi: 10.4103/0019-5413.38584. PMID: 19823658; PMCID: PMC2759586.
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Three-dimensional structure of cytochrome c' from two Alcaligenes species and the implications for four-helix bundle structures.

Acta crystallographica. Section D, Biological crystallography

Dobbs AJ, Anderson BF, Faber HR, Baker EN.
PMID: 15299707
Acta Crystallogr D Biol Crystallogr. 1996 Mar 01;52:356-68. doi: 10.1107/S0907444995008328.

The three-dimensional structures of two cytochromes c' have been determined in order to analyse the common features of proteins of this family and their relationship with other four-helix bundle structures. The structure of cytochrome c' from Alcaligenes sp was...

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Dobbs AJ, Anderson BF, Faber HR, et al. Three-dimensional structure of cytochrome c' from two Alcaligenes species and the implications for four-helix bundle structures. Acta Crystallogr D Biol Crystallogr. 1996;52:356-68doi: 10.1107/S0907444995008328.
Dobbs, A. J., Anderson, B. F., Faber, H. R., & Baker, E. N. (1996). Three-dimensional structure of cytochrome c' from two Alcaligenes species and the implications for four-helix bundle structures. Acta crystallographica. Section D, Biological crystallography, 52356-68. https://doi.org/10.1107/S0907444995008328
Dobbs, A J, et al. "Three-dimensional structure of cytochrome c' from two Alcaligenes species and the implications for four-helix bundle structures." Acta crystallographica. Section D, Biological crystallography vol. 52 (1996): 356-68. doi: https://doi.org/10.1107/S0907444995008328
Dobbs AJ, Anderson BF, Faber HR, Baker EN. Three-dimensional structure of cytochrome c' from two Alcaligenes species and the implications for four-helix bundle structures. Acta Crystallogr D Biol Crystallogr. 1996 Mar 01;52:356-68. doi: 10.1107/S0907444995008328. PMID: 15299707.
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Showing 1 to 12 of 140 entries