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Showing 1 to 12 of 32 entries
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New melanocortin-like peptide of .

NPJ biofilms and microbiomes

Qiang X, Liotta AS, Shiloach J, Gutierrez JC, Wang H, Ochani M, Ochani K, Yang H, Rabin A, LeRoith D, Lesniak MA, Böhm M, Maaser C, Kannengiesser K, Donowitz M, Rabizadeh S, Czura CJ, Tracey KJ, Westlake M, Zarfeshani A, Mehdi SF, Danoff A, Ge X, Sanyal S, Schwartz GJ, Roth J.
PMID: 29152323
NPJ Biofilms Microbiomes. 2017 Nov 13;3:31. doi: 10.1038/s41522-017-0039-9. eCollection 2017.

No abstract available.

A NHE3-related pseudogene is on human Chromosome 10; the functional gene maps to 5pl5.3.

Mammalian genome : official journal of the International Mammalian Genome Society

Kokke FT, Elsawy T, Bengtsson U, Wasmuth JJ, Wang Jabs E, Tse CM, Donowitz M, Brant SR.
PMID: 27517869
Mamm Genome. 1996 Mar;7(3):235-6. doi: 10.1007/s003359900066.

No abstract available.

Small Intestine Bacterial Overgrowth in Bangladeshi Infants Is Associated With Growth Stunting in a Longitudinal Cohort.

The American journal of gastroenterology

Donowitz JR, Pu Z, Lin Y, Alam M, Ferdous T, Shama T, Taniuchi M, Islam MO, Kabir M, Nayak U, Faruque ASG, Haque R, Ma JZ, Petri WA.
PMID: 34693912
Am J Gastroenterol. 2021 Oct 25; doi: 10.14309/ajg.0000000000001535. Epub 2021 Oct 25.

INTRODUCTION: Small intestine bacterial overgrowth (SIBO) is common in children from low-income countries and has been cross-sectionally associated with growth stunting. We sought to determine whether SIBO was associated with poor growth and neurodevelopmental in a longitudinal analysis.METHODS: We...

Chronic Inflammation in Ulcerative Colitis Causes Long-Term Changes in Goblet Cell Function.

Cellular and molecular gastroenterology and hepatology

Singh V, Johnson K, Yin J, Lee S, Lin R, Yu H, In J, Foulke-Abel J, Zachos NC, Donowitz M, Rong Y.
PMID: 34418586
Cell Mol Gastroenterol Hepatol. 2022;13(1):219-232. doi: 10.1016/j.jcmgh.2021.08.010. Epub 2021 Aug 18.

BACKGROUND & AIMS: One of the features of ulcerative colitis (UC) is a defect in the protective mucus layer. This has been attributed to a reduced number of goblet cells (GCs). However, it is not known whether abnormal GC...

SARS-COV-2 induced Diarrhea is inflammatory, Ca .

bioRxiv : the preprint server for biology

Donowitz M, Tse CM, Dokladny K, Rawat M, Horwitz I, Ye C, Kell A, Lin R, Lee S, Guo C, Tsai SJ, Cox A, Gould S, In J, Bradfute S, Zachos NC, Kovbasnjuk O.
PMID: 33948596
bioRxiv. 2021 Apr 28; doi: 10.1101/2021.04.27.441695.

Diarrhea occurs in 2-50% of cases of COVID-19 (∼8% is average across series). The diarrhea does not appear to account for the disease mortality and its contribution to the morbidity has not been defined, even though it is a...

Chronic Inflammation in Ulcerative Colitis Causes Long-Term Changes in Goblet Cell Function.

Cellular and molecular gastroenterology and hepatology

Singh V, Johnson K, Yin J, Lee S, Lin R, Yu H, In J, Foulke-Abel J, Zachos NC, Donowitz M, Rong Y.
PMID: 34418586
Cell Mol Gastroenterol Hepatol. 2022;13(1):219-232. doi: 10.1016/j.jcmgh.2021.08.010. Epub 2021 Aug 18.

BACKGROUND & AIMS: One of the features of ulcerative colitis (UC) is a defect in the protective mucus layer. This has been attributed to a reduced number of goblet cells (GCs). However, it is not known whether abnormal GC...

Practical Advice From a Basic and Translational Researcher at a Major Medical School.

Cellular and molecular gastroenterology and hepatology

Donowitz M.
PMID: 28174742
Cell Mol Gastroenterol Hepatol. 2016 Sep 06;2(6):707-709. doi: 10.1016/j.jcmgh.2016.08.002. eCollection 2016 Nov.

No abstract available.

The uncertain state of work in the U.S.: Profiles of decent work and precarious work.

Journal of vocational behavior

Blustein DL, Perera HN, Diamonti AJ, Gutowski E, Meerkins T, Davila A, Erby W, Konowitz L.
PMID: 32868953
J Vocat Behav. 2020 Oct;122:103481. doi: 10.1016/j.jvb.2020.103481. Epub 2020 Aug 26.

This research utilized a person-centered approach to identify profiles of decent work and precarious work, which were explored due to their centrality in current debates about the uncertain state of work conditions in the U.S. Using the Decent Work...

Microfluidics platform for measurement of volume changes in immobilized intestinal enteroids.

Biomicrofluidics

Jin BJ, Battula S, Zachos N, Kovbasnjuk O, Fawlke-Abel J, In J, Donowitz M, Verkman AS.
PMID: 24738013
Biomicrofluidics. 2014 Apr 01;8(2):024106. doi: 10.1063/1.4870400. eCollection 2014 Mar.

Intestinal enteroids are ex vivo primary cultured single-layer epithelial cell spheroids of average diameter ∼150 μm with luminal surface facing inward. Measurement of enteroid swelling in response to secretagogues has been applied to genetic testing in cystic fibrosis and...

Chronic Inflammation in Ulcerative Colitis Causes Long-Term Changes in Goblet Cell Function.

Cellular and molecular gastroenterology and hepatology

Singh V, Johnson K, Yin J, Lee S, Lin R, Yu H, In J, Foulke-Abel J, Zachos NC, Donowitz M, Rong Y.
PMID: 34418586
Cell Mol Gastroenterol Hepatol. 2022;13(1):219-232. doi: 10.1016/j.jcmgh.2021.08.010. Epub 2021 Aug 18.

BACKGROUND & AIMS: One of the features of ulcerative colitis (UC) is a defect in the protective mucus layer. This has been attributed to a reduced number of goblet cells (GCs). However, it is not known whether abnormal GC...

Increased Fecal .

Open forum infectious diseases

Donowitz JR, Parikh HI, Taniuchi M, Gilchrist CA, Haque R, Kirkpatrick BD, Alam M, Kakon SH, Islam BZ, Afreen S, Kabir M, Nayak U, Colgate ER, Carmolli MP, Petri WA.
PMID: 31281862
Open Forum Infect Dis. 2019 Jun 01;6(7):ofz266. doi: 10.1093/ofid/ofz266. eCollection 2019 Jul.

BACKGROUND: Glucose hydrogen breath testing is a noninvasive test for small intestine bacterial overgrowth (SIBO). A positive glucose hydrogen breath test is common in children from low-income countries and has been found to be associated with malnutrition as measured...

Patients' perspectives on the derivation and use of organoids.

Stem cell reports

Bollinger J, May E, Mathews D, Donowitz M, Sugarman J.
PMID: 34329595
Stem Cell Reports. 2021 Aug 10;16(8):1874-1883. doi: 10.1016/j.stemcr.2021.07.004. Epub 2021 Jul 29.

Organoid research is enhancing understanding of human development and diseases as well as aiding in medication development and selection, raising hopes for even more future therapeutic options. Nevertheless, this work raises important ethical issues and there is a paucity...

Showing 1 to 12 of 32 entries