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Showing 1 to 12 of 26 entries
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[[Current approaches to diagnosing and treating nonalcoholic fatty liver disease].

Terapevticheskii arkhiv

Drapkina OM, Deeva TA, Volkova NP, Ivashkin VT.
PMID: 25509904
Ter Arkh. 2014;86(10):116-23.

Nonalcoholic fatty liver disease (NAFLD) is associated with major cardiovascular risk factors, such as type 2 diabetes mellitus, obesity, dyslipidemia, hypertension, and insulin resistance, and has been recently considered to be a new component of metabolic syndrome and it...

Cell-Free Circulating Nucleic Acids as Early Biomarkers for NAFLD and NAFLD-Associated Disorders.

Frontiers in physiology

Turchinovich A, Baranova A, Drapkina O, Tonevitsky A.
PMID: 30294278
Front Physiol. 2018 Sep 20;9:1256. doi: 10.3389/fphys.2018.01256. eCollection 2018.

Non-alcoholic fatty liver disease (NAFLD) is the worldwide most common cause of chronic liver pathology, which prevalence strongly correlates with the increasing incidence of diabetes, obesity and metabolic syndrome in the general population. Simple steatosis, the earliest NAFLD stage,...

Case Report: Hypertriglyceridemia and Premature Atherosclerosis in a Patient With Apolipoprotein E Gene ε.

Frontiers in cardiovascular medicine

Limonova AS, Ershova AI, Meshkov AN, Kiseleva AV, Divashuk MG, Kutsenko VA, Drapkina OM.
PMID: 33537346
Front Cardiovasc Med. 2021 Jan 18;7:585779. doi: 10.3389/fcvm.2020.585779. eCollection 2020.

We present a case of a 40-year-old male with premature atherosclerosis, with evidence of both eruptive and tendinous xanthomas, which could imply an increase in both low-density lipoprotein (LDL) and triglyceride (TG) levels. However, his LDL was 2.08 mmol/l,...

A Data-Driven Approach to Carrier Screening for Common Recessive Diseases.

Journal of personalized medicine

Kiseleva AV, Klimushina MV, Sotnikova EA, Divashuk MG, Ershova AI, Skirko OP, Kurilova OV, Zharikova AA, Khlebus EY, Efimova IA, Pokrovskaya MS, Slominsky PA, Shalnova SA, Meshkov AN, Drapkina OM.
PMID: 32971794
J Pers Med. 2020 Sep 22;10(3). doi: 10.3390/jpm10030140.

Genetic screening is an advanced tool for reducing recessive disease burden. Nowadays, it is still unclear as to the number of genes or their variants that are necessary for effective screening. This paper describes the development of a carrier...

[Nutrition status and obesity paradox in chronic obstructive pulmonary disease].

Voprosy pitaniia

Drapkina OM, Avdeev SN, Budnevsky AV, Ovsyannikov ES, Kontsevaya AV, Drobysheva ES.
PMID: 35032123
Vopr Pitan. 2021;90(6):42-49. doi: 10.33029/0042-8833-2021-90-6-42-49. Epub 2021 Oct 26.

Chronic obstructive pulmonary disease (COPD) is one of the main causes of increasing morbidity and mortality worldwide, and therefore is becoming a major public health problem.

[Place of vitamin D in the prevention of premature aging and the development of age-associated diseases].

Terapevticheskii arkhiv

Drapkina OM, Shepel RN, Fomin VV, Svistunov AA.
PMID: 32598654
Ter Arkh. 2018 Jan 15;90(1):69-75. doi: 10.17116/terarkh201890169-75.

There is an ongoing search for the molecular and biochemical mechanisms underlying the development of aging and age-associated diseases. At the same time there is growing evidence geroprotective properties of vitamin D.In this review, described in detail the possible...

[Optimal Control Strategy Allies in Blood Pressure].

Kardiologiia

Drapkina O M, Eliashevich S O.
PMID: 28294850
Kardiologiia. 2015 Mar;55(3):106-114. doi: 10.18565/cardio.2015.3.106-114.

OBJECTIVE: to review the available results of clinical trials on the efficacy and safety of a fixed combination of an angiotensin-converting enzyme (ACE) inhibitor lisinopril and the calcium antagonist amlodipine, including an analysis of the actual antihypertensive effect and...

Parameters of cutaneous microvasculature in men of working age with newly diagnosed arterial hypertension.

Clinical hemorheology and microcirculation

Korolev AI, Fedorovich AA, Gorshkov AY, Dadaeva VA, Kim OT, Omelyanenko KV, Mikhaylova MA, Vasilyev DK, Dzhioeva ON, Akasheva DU, Drapkina OM.
PMID: 34719487
Clin Hemorheol Microcirc. 2021 Oct 24; doi: 10.3233/CH-211292. Epub 2021 Oct 24.

OBJECTIVE: To investigate structural and functional features of cutaneous microvasculature in men of working age with newly diagnosed arterial hypertension (AH).MATERIALS AND METHODS: The study included 161 apparently healthy men from 30 to 60 years, who underwent a comprehensive...

Sudden gains among women receiving treatment for alcohol use disorders.

Addiction research & theory

Drapkin M, Epstein EE, McCrady B, Eddie D.
PMID: 33568968
Addict Res Theory. 2015;23(4):273-279. doi: 10.3109/16066359.2014.981809. Epub 2014 Nov 21.

Understanding the timing and types of change during treatment for mental health disorders is an important step toward elucidating possible mechanisms of behaviour change in response to therapeutic interventions, yet these issues have not been adequately addressed in the...

The Prevalence of Heterozygous Familial Hypercholesterolemia in Selected Regions of the Russian Federation: The FH-ESSE-RF Study.

Journal of personalized medicine

Meshkov AN, Ershova AI, Kiseleva AV, Shalnova SA, Drapkina OM, Boytsov SA, On Behalf Of The Fh-Esse-Rf Investigators.
PMID: 34074024
J Pers Med. 2021 May 24;11(6). doi: 10.3390/jpm11060464.

Heterozygous familial hypercholesterolemia (HeFH) is one of the most common genetic conditions but remains substantially underdiagnosed. The aim of our study was to investigate the prevalence of HeFH in the population of 11 different regions of Russia. Individuals were...

[Efficacy and Safety of Rosuvastatin in Patients of Different Risk Groups of Developing Cardiovascular].

Kardiologiia

Drapkina OM, Eliashevich SO.
PMID: 28294815
Kardiologiia. 2015 Feb;55(2):72-81.

The purpose of the review - analysis of randomized clinical trials to evaluate the efficacy and safety of rosuvastatin in respect of primary and secondary prevention of cardiovascular events, as well as in patients with acute coronary syndrome. As...

Treatment choices and subsequent attendance by substance-dependent patients who disengage from intensive outpatient treatment.

Addiction research & theory

Van Horn DH, Drapkin M, Lynch KG, Rennert L, Goodman JD, Thomas T, Ivey M, McKay JR.
PMID: 27667970
Addict Res Theory. 2015;23(5):391-403. doi: 10.3109/16066359.2015.1017570. Epub 2015 Apr 22.

In an effort to increase engagement in effective treatment, we offered a choice of alternate evidence-based treatments to 137 alcohol- or cocaine-dependent adults (110 males, 27 females) who entered an intensive outpatient program (IOP) but disengaged within the first...

Showing 1 to 12 of 26 entries