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Showing 1 to 12 of 68 entries
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Practical recommendations for the use of therapeutic drug monitoring of biopharmaceuticals in inflammatory diseases.

Clinical pharmacology : advances and applications

Dreesen E, Bossuyt P, Mulleman D, Gils A, Pascual-Salcedo D.
PMID: 29042821
Clin Pharmacol. 2017 Oct 03;9:101-111. doi: 10.2147/CPAA.S138414. eCollection 2017.

Biopharmaceuticals directed against tumor necrosis factor-alpha, integrins, interleukins, interferons and their receptors have become key agents for the management of inflammatory diseases in the fields of gastroenterology, rheumatology, dermatology and neurology. However, response to these treatments is far from...

Partial purification and characterization of a Ca(2+)-stimulated lipoxygenase from soybean seeds.

Lipids

Dreesen TD, Dickens M, Koch RB.
PMID: 27519438
Lipids. 1982 Dec;17(12):964-9. doi: 10.1007/BF02534593.

A highly purified Ca(2+)-stimulated lipoxygenase was isolated from the Hill variety of soybean seeds. Separation of Ca(2+)-stimulated lipoxygenase from lipoxygenase active in the absence of Ca(2+) (lipoxygenase-1) was readily obtained using a DEAE-cellulose column. Sample size applied to the...

Glass Microparticulate Ingestion: An Unusual and Difficult-to-Diagnose Cause of Chronic Abdominal Pain.

ACG case reports journal

Vance RB, Mühlbauer M, Dreesen EB, Bagnell CR, Dent GA, Herfarth H, Jobin C, Dellon ES.
PMID: 26157853
ACG Case Rep J. 2014 Apr 04;1(3):137-9. doi: 10.14309/crj.2014.29. eCollection 2014 Apr.

In the absence of overt structural abnormalities, the diagnostic approach to chronic abdominal pain can be challenging. Occupational particulate inhalation causing injury to an organ other than the lung is rare. We report a case of inadvertent glass microparticulate...

Picosecond laser for performance of efficient nonlinear spectroscopy from 10 to 21 microm.

Optics letters

Mani AA, Schultz ZD, Gewirth AA, White JO, Caudano Y, Humbert C, Dreesen L, Thiry PA, Peremans A.
PMID: 14759049
Opt Lett. 2004 Feb 01;29(3):274-6. doi: 10.1364/ol.29.000274.

Laser tunability from 10 to 21 microm is obtained by use of an optical parametric oscillator based on a KTP crystal followed by a difference-frequency stage with a CdSe crystal. An all-solid-state picosecond Nd:YAG oscillator mode locked by a...

Prediction of Functional Outcome After Acute Ischemic Stroke: Comparison of the CT-DRAGON Score and a Reduced Features Set.

Frontiers in neurology

Lesenne A, Grieten J, Ernon L, Wibail A, Stockx L, Wouters PF, Dreesen L, Vandermeulen E, Van Boxstael S, Vanelderen P, Van Poucke S, Vundelinckx J, Van Cauter S, Mesotten D.
PMID: 32849196
Front Neurol. 2020 Jul 31;11:718. doi: 10.3389/fneur.2020.00718. eCollection 2020.

No abstract available.

Vital Signs Prediction for COVID-19 Patients in ICU.

Sensors (Basel, Switzerland)

Youssef Ali Amer A, Wouters F, Vranken J, Dreesen P, de Korte-de Boer D, van Rosmalen F, van Bussel BCT, Smit-Fun V, Duflot P, Guiot J, van der Horst ICC, Mesotten D, Vandervoort P, Aerts JM, Vanrumste B.
PMID: 34884136
Sensors (Basel). 2021 Dec 05;21(23). doi: 10.3390/s21238131.

This study introduces machine learning predictive models to predict the future values of the monitored vital signs of COVID-19 ICU patients. The main vital sign predictors include heart rate, respiration rate, and oxygen saturation. We investigated the performances of...

Potential effects of COVID-19 school closures on foundational skills and Country responses for mitigating learning loss.

International journal of educational development

Alban Conto C, Akseer S, Dreesen T, Kamei A, Mizunoya S, Rigole A.
PMID: 34658500
Int J Educ Dev. 2021 Nov;87:102434. doi: 10.1016/j.ijedudev.2021.102434. Epub 2021 Oct 11.

This article investigates to what extent disrupted schooling and dropout affects children's acquisition of foundational skills prior to and during the COVID-19 pandemic. Using household survey data from thirteen low- and lower-middle-income countries, we find that missing or dropping...

Ustekinumab Dosing Individualization in Crohn's Disease Guided by a Population Pharmacokinetic-Pharmacodynamic Model.

Pharmaceutics

Aguiar Zdovc J, Hanžel J, Kurent T, Sever N, Koželj M, Smrekar N, Novak G, Štabuc B, Dreesen E, Thomas D, Vovk T, Ostanek B, Drobne D, Grabnar I.
PMID: 34683880
Pharmaceutics. 2021 Sep 30;13(10). doi: 10.3390/pharmaceutics13101587.

Ustekinumab is a monoclonal antibody used in Crohn's disease (CD). Dose optimization in case of non-response and the role of pharmacokinetic-pharmacodynamic (PK-PD) monitoring remain unresolved dilemmas in clinical practice. We aimed to develop a population PK-PD model for ustekinumab...

P53 induces senescence in the unstable progeny of aneuploid cells.

Cell cycle (Georgetown, Tex.)

Giam M, Wong CK, Low JS, Sinelli M, Dreesen O, Rancati G.
PMID: 33305692
Cell Cycle. 2020 Dec;19(24):3508-3520. doi: 10.1080/15384101.2020.1850968. Epub 2020 Dec 11.

Aneuploidy is the condition of having an imbalanced karyotype, which is associated with tumor initiation, evolution, and acquisition of drug-resistant features, possibly by generating heterogeneous populations of cells with distinct genotypes and phenotypes. Multicellular eukaryotes have therefore evolved a...

Discrepancies between ePrescriptions and dispensing in Belgium, 6 years after the launch of the electronic prescribing - a mixed-method study.

Acta clinica Belgica

Van Laere S, Tommelein E, Dreesen E, Buyl R, Cornu P.
PMID: 33586629
Acta Clin Belg. 2021 Feb 13;1-10. doi: 10.1080/17843286.2021.1885884. Epub 2021 Feb 13.

No abstract available.

Should Anesthesiologists and Surgeons Take Breaks During Cases?.

AMA journal of ethics

Scarlet S, Dreesen EB.
PMID: 32345424
AMA J Ethics. 2020 Apr 01;22(4):E312-318. doi: 10.1001/amajethics.2020.312.

Anesthesiologists regularly take breaks during operations, whereas surgeons do so more rarely. This article considers the origins of this difference in practice in relation to different characteristics of the work of these 2 specialties as well as differences in...

Sub-millisecond time-resolved small-angle neutron scattering measurements at NIST.

Journal of applied crystallography

Glinka C, Bleuel M, Tsai P, Zákutná D, Honecker D, Dresen D, Mees F, Disch S.
PMID: 32684874
J Appl Crystallogr. 2020 Apr 14;53:598-604. doi: 10.1107/S1600576720004367. eCollection 2020 Jun 01.

Instrumentation for time-resolved small-angle neutron scattering measurements with sub-millisecond time resolution, based on Gähler's TISANE (time-involved small-angle neutron experiments) concept, is in operation at NIST's Center for Neutron Research. This implementation of the technique includes novel electronics for synchronizing...

Showing 1 to 12 of 68 entries