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Nickel-Catalyzed Enantioselective Pyridone C-H Functionalizations Enabled by a Bulky N-Heterocyclic Carbene Ligand.

Journal of the American Chemical Society

Diesel J, Finogenova AM, Cramer N.
PMID: 29543449
J Am Chem Soc. 2018 Apr 04;140(13):4489-4493. doi: 10.1021/jacs.8b01181. Epub 2018 Mar 20.

Annulated pyridones are an important scaffold found in many biologically active compounds. A Ni(0)-catalyzed C-H functionalization of 2- and 4-pyridones is disclosed, providing access to annulated pyridones via enantioselective intramolecular olefin hydroarylation. Key to the success of the transformation...

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Diesel J, Finogenova AM, Cramer N. Nickel-Catalyzed Enantioselective Pyridone C-H Functionalizations Enabled by a Bulky N-Heterocyclic Carbene Ligand. J Am Chem Soc. 2018;140(13):4489-4493doi: 10.1021/jacs.8b01181.
Diesel, J., Finogenova, A. M., & Cramer, N. (2018). Nickel-Catalyzed Enantioselective Pyridone C-H Functionalizations Enabled by a Bulky N-Heterocyclic Carbene Ligand. Journal of the American Chemical Society, 140(13), 4489-4493. https://doi.org/10.1021/jacs.8b01181
Diesel, Johannes, et al. "Nickel-Catalyzed Enantioselective Pyridone C-H Functionalizations Enabled by a Bulky N-Heterocyclic Carbene Ligand." Journal of the American Chemical Society vol. 140,13 (2018): 4489-4493. doi: https://doi.org/10.1021/jacs.8b01181
Diesel J, Finogenova AM, Cramer N. Nickel-Catalyzed Enantioselective Pyridone C-H Functionalizations Enabled by a Bulky N-Heterocyclic Carbene Ligand. J Am Chem Soc. 2018 Apr 04;140(13):4489-4493. doi: 10.1021/jacs.8b01181. Epub 2018 Mar 20. PMID: 29543449.
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Medical Management of Cyclosporine-Induced Gingival Overgrowth Using Oral Azithromycin in Six Dogs.

Veterinary sciences

Diesel A, Moriello K.
PMID: 29061926
Vet Sci. 2015 Feb 05;2(1):13-22. doi: 10.3390/vetsci2010013.

Gingival overgrowth is an uncommon adverse effect of cyclosporine administration in veterinary species. In people, gingival overgrowth is a common complication of cyclosporine administration for immunosuppression, generally following transplant procedures. Azithromycin has been used successfully for managing gingival overgrowth...

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Diesel A, Moriello K. Medical Management of Cyclosporine-Induced Gingival Overgrowth Using Oral Azithromycin in Six Dogs. Vet Sci. 2015;2(1):13-22doi: 10.3390/vetsci2010013.
Diesel, A., & Moriello, K. (2015). Medical Management of Cyclosporine-Induced Gingival Overgrowth Using Oral Azithromycin in Six Dogs. Veterinary sciences, 2(1), 13-22. https://doi.org/10.3390/vetsci2010013
Diesel, Alison, and Moriello, Karen. "Medical Management of Cyclosporine-Induced Gingival Overgrowth Using Oral Azithromycin in Six Dogs." Veterinary sciences vol. 2,1 (2015): 13-22. doi: https://doi.org/10.3390/vetsci2010013
Diesel A, Moriello K. Medical Management of Cyclosporine-Induced Gingival Overgrowth Using Oral Azithromycin in Six Dogs. Vet Sci. 2015 Feb 05;2(1):13-22. doi: 10.3390/vetsci2010013. PMID: 29061926; PMCID: PMC5644608.
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Cutaneous Hypersensitivity Dermatoses in the Feline Patient: A Review of Allergic Skin Disease in Cats.

Veterinary sciences

Diesel A.
PMID: 29056684
Vet Sci. 2017 May 09;4(2). doi: 10.3390/vetsci4020025.

Feline allergic skin disease presents a unique set of challenges to the veterinary practitioner. Although there is some similarity to what is seen in the allergic canine patient, cutaneous hypersensitivity dermatoses in cats can manifest with strikingly different clinical...

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Diesel A. Cutaneous Hypersensitivity Dermatoses in the Feline Patient: A Review of Allergic Skin Disease in Cats. Vet Sci. 2017;4(2)doi: 10.3390/vetsci4020025.
Diesel, A. (2017). Cutaneous Hypersensitivity Dermatoses in the Feline Patient: A Review of Allergic Skin Disease in Cats. Veterinary sciences, 4(2), . https://doi.org/10.3390/vetsci4020025
Diesel, Alison. "Cutaneous Hypersensitivity Dermatoses in the Feline Patient: A Review of Allergic Skin Disease in Cats." Veterinary sciences vol. 4,2 (2017). doi: https://doi.org/10.3390/vetsci4020025
Diesel A. Cutaneous Hypersensitivity Dermatoses in the Feline Patient: A Review of Allergic Skin Disease in Cats. Vet Sci. 2017 May 09;4(2). doi: 10.3390/vetsci4020025. PMID: 29056684; PMCID: PMC5606602.
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A global dataset of crowdsourced land cover and land use reference data.

Scientific data

Fritz S, See L, Perger C, McCallum I, Schill C, Schepaschenko D, Duerauer M, Karner M, Dresel C, Laso-Bayas JC, Lesiv M, Moorthy I, Salk CF, Danylo O, Sturn T, Albrecht F, You L, Kraxner F, Obersteiner M.
PMID: 28608851
Sci Data. 2017 Jun 13;4:170075. doi: 10.1038/sdata.2017.75.

Global land cover is an essential climate variable and a key biophysical driver for earth system models. While remote sensing technology, particularly satellites, have played a key role in providing land cover datasets, large discrepancies have been noted among...

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Fritz S, See L, Perger C, et al. A global dataset of crowdsourced land cover and land use reference data. Sci Data. 2017;4:170075doi: 10.1038/sdata.2017.75.
Fritz, S., See, L., Perger, C., McCallum, I., Schill, C., Schepaschenko, D., Duerauer, M., Karner, M., Dresel, C., Laso-Bayas, J. C., Lesiv, M., Moorthy, I., Salk, C. F., Danylo, O., Sturn, T., Albrecht, F., You, L., Kraxner, F., & Obersteiner, M. (2017). A global dataset of crowdsourced land cover and land use reference data. Scientific data, 4170075. https://doi.org/10.1038/sdata.2017.75
Fritz, Steffen, et al. "A global dataset of crowdsourced land cover and land use reference data." Scientific data vol. 4 (2017): 170075. doi: https://doi.org/10.1038/sdata.2017.75
Fritz S, See L, Perger C, McCallum I, Schill C, Schepaschenko D, Duerauer M, Karner M, Dresel C, Laso-Bayas JC, Lesiv M, Moorthy I, Salk CF, Danylo O, Sturn T, Albrecht F, You L, Kraxner F, Obersteiner M. A global dataset of crowdsourced land cover and land use reference data. Sci Data. 2017 Jun 13;4:170075. doi: 10.1038/sdata.2017.75. PMID: 28608851; PMCID: PMC5469313.
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Neuronal Oscillations in Various Frequency Bands Differ between Pain and Touch.

Frontiers in human neuroscience

Michail G, Dresel C, Witkovský V, Stankewitz A, Schulz E.
PMID: 27199705
Front Hum Neurosci. 2016 Apr 29;10:182. doi: 10.3389/fnhum.2016.00182. eCollection 2016.

Although humans are generally capable of distinguishing single events of pain or touch, recent research suggested that both modalities activate a network of similar brain regions. By contrast, less attention has been paid to which processes uniquely contribute to...

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Michail G, Dresel C, Witkovský V, et al. Neuronal Oscillations in Various Frequency Bands Differ between Pain and Touch. Front Hum Neurosci. 2016;10:182doi: 10.3389/fnhum.2016.00182.
Michail, G., Dresel, C., Witkovský, V., Stankewitz, A., & Schulz, E. (2016). Neuronal Oscillations in Various Frequency Bands Differ between Pain and Touch. Frontiers in human neuroscience, 10182. https://doi.org/10.3389/fnhum.2016.00182
Michail, Georgios, et al. "Neuronal Oscillations in Various Frequency Bands Differ between Pain and Touch." Frontiers in human neuroscience vol. 10 (2016): 182. doi: https://doi.org/10.3389/fnhum.2016.00182
Michail G, Dresel C, Witkovský V, Stankewitz A, Schulz E. Neuronal Oscillations in Various Frequency Bands Differ between Pain and Touch. Front Hum Neurosci. 2016 Apr 29;10:182. doi: 10.3389/fnhum.2016.00182. eCollection 2016. PMID: 27199705; PMCID: PMC4850848.
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Antibacterial activities and structure-activity relationships of a panel of 48 compounds from Kenyan plants against multidrug resistant phenotypes.

SpringerPlus

Omosa LK, Midiwo JO, Mbaveng AT, Tankeo SB, Seukep JA, Voukeng IK, Dzotam JK, Isemeki J, Derese S, Omolle RA, Efferth T, Kuete V.
PMID: 27386347
Springerplus. 2016 Jun 27;5(1):901. doi: 10.1186/s40064-016-2599-1. eCollection 2016.

In the current study forty eight compounds belonging to anthraquinones, naphthoquinones, benzoquinones, flavonoids (chalcones and polymethoxylated flavones) and diterpenoids (clerodanes and kauranes) were explored for their antimicrobial potential against a panel of sensitive and multi-drug resistant Gram-negative and Gram-positive...

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Omosa LK, Midiwo JO, Mbaveng AT, et al. Antibacterial activities and structure-activity relationships of a panel of 48 compounds from Kenyan plants against multidrug resistant phenotypes. Springerplus. 2016;5(1):901doi: 10.1186/s40064-016-2599-1.
Omosa, L. K., Midiwo, J. O., Mbaveng, A. T., Tankeo, S. B., Seukep, J. A., Voukeng, I. K., Dzotam, J. K., Isemeki, J., Derese, S., Omolle, R. A., Efferth, T., & Kuete, V. (2016). Antibacterial activities and structure-activity relationships of a panel of 48 compounds from Kenyan plants against multidrug resistant phenotypes. SpringerPlus, 5(1), 901. https://doi.org/10.1186/s40064-016-2599-1
Omosa, Leonidah K, et al. "Antibacterial activities and structure-activity relationships of a panel of 48 compounds from Kenyan plants against multidrug resistant phenotypes." SpringerPlus vol. 5,1 (2016): 901. doi: https://doi.org/10.1186/s40064-016-2599-1
Omosa LK, Midiwo JO, Mbaveng AT, Tankeo SB, Seukep JA, Voukeng IK, Dzotam JK, Isemeki J, Derese S, Omolle RA, Efferth T, Kuete V. Antibacterial activities and structure-activity relationships of a panel of 48 compounds from Kenyan plants against multidrug resistant phenotypes. Springerplus. 2016 Jun 27;5(1):901. doi: 10.1186/s40064-016-2599-1. eCollection 2016. PMID: 27386347; PMCID: PMC4923020.
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International collaboration to enhance the fight against HIV/AIDS: report of a consultative meeting between the University of Buea in Cameroon and the Goldfarb School of Nursing in the USA.

Journal of public health in Africa

Nsagha DS, Rosenburg N, Diesel H, Sab CM, Taliaferro D.
PMID: 28299063
J Public Health Afr. 2011 Sep 05;2(2):e22. doi: 10.4081/jphia.2011.e22. eCollection 2011 Sep 05.

HIV/AIDS is a major public health pandemic affecting the development, survival and life of young people both in Cameroon and the USA. Youths are more adaptive to change and less hindered by prejudice than adults. Student-to-student peer mentoring is...

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Nsagha DS, Rosenburg N, Diesel H, et al. International collaboration to enhance the fight against HIV/AIDS: report of a consultative meeting between the University of Buea in Cameroon and the Goldfarb School of Nursing in the USA. J Public Health Afr. 2011;2(2):e22doi: 10.4081/jphia.2011.e22.
Nsagha, D. S., Rosenburg, N., Diesel, H., Sab, C. M., & Taliaferro, D. (2011). International collaboration to enhance the fight against HIV/AIDS: report of a consultative meeting between the University of Buea in Cameroon and the Goldfarb School of Nursing in the USA. Journal of public health in Africa, 2(2), e22. https://doi.org/10.4081/jphia.2011.e22
Nsagha, Dickson S, et al. "International collaboration to enhance the fight against HIV/AIDS: report of a consultative meeting between the University of Buea in Cameroon and the Goldfarb School of Nursing in the USA." Journal of public health in Africa vol. 2,2 (2011): e22. doi: https://doi.org/10.4081/jphia.2011.e22
Nsagha DS, Rosenburg N, Diesel H, Sab CM, Taliaferro D. International collaboration to enhance the fight against HIV/AIDS: report of a consultative meeting between the University of Buea in Cameroon and the Goldfarb School of Nursing in the USA. J Public Health Afr. 2011 Sep 05;2(2):e22. doi: 10.4081/jphia.2011.e22. eCollection 2011 Sep 05. PMID: 28299063; PMCID: PMC5345495.
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Electrospray-ionization MS/MS library of drugs as database for method development and drug identification.

Forensic science international

Dresen S, Kempf J, Weinmann W.
PMID: 16860958
Forensic Sci Int. 2006 Sep 12;161(2):86-91. doi: 10.1016/j.forsciint.2006.02.053. Epub 2006 Jul 24.

An ESI MS/MS library of 800 compounds has been developed and a collection of data is now available for Analyst 1.4 and higher. Compounds include forensically important drugs, such as illegal drugs, some deuterated analogues, hypnotics, amphetamines, benzodiazepines, neuroleptics,...

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Dresen S, Kempf J, Weinmann W. Electrospray-ionization MS/MS library of drugs as database for method development and drug identification. Forensic Sci Int. 2006;161(2):86-91doi: 10.1016/j.forsciint.2006.02.053.
Dresen, S., Kempf, J., & Weinmann, W. (2006). Electrospray-ionization MS/MS library of drugs as database for method development and drug identification. Forensic science international, 161(2), 86-91. https://doi.org/10.1016/j.forsciint.2006.02.053
Dresen, Sebastian, et al. "Electrospray-ionization MS/MS library of drugs as database for method development and drug identification." Forensic science international vol. 161,2 (2006): 86-91. doi: https://doi.org/10.1016/j.forsciint.2006.02.053
Dresen S, Kempf J, Weinmann W. Electrospray-ionization MS/MS library of drugs as database for method development and drug identification. Forensic Sci Int. 2006 Sep 12;161(2):86-91. doi: 10.1016/j.forsciint.2006.02.053. Epub 2006 Jul 24. PMID: 16860958.
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Testing of rod objects by grazing-incidence interferometry: experiment.

Applied optics

Brinkmann S, Dresel T, Schreiner R, Schwider J.
PMID: 18305594
Appl Opt. 1999 Jan 01;38(1):121-5. doi: 10.1364/ao.38.000121.

A grazing-incidence interferometer for the testing of technical surfaces for macroscopic surface deviations is described. Computer-generated holograms serve as beam splitters and references for the workpieces tested. The sensitivity of the interferometer depends on the period of the computer-generated...

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Brinkmann S, Dresel T, Schreiner R, et al. Testing of rod objects by grazing-incidence interferometry: experiment. Appl Opt. 1999;38(1):121-5doi: 10.1364/ao.38.000121.
Brinkmann, S., Dresel, T., Schreiner, R., & Schwider, J. (1999). Testing of rod objects by grazing-incidence interferometry: experiment. Applied optics, 38(1), 121-5. https://doi.org/10.1364/ao.38.000121
Brinkmann, S, et al. "Testing of rod objects by grazing-incidence interferometry: experiment." Applied optics vol. 38,1 (1999): 121-5. doi: https://doi.org/10.1364/ao.38.000121
Brinkmann S, Dresel T, Schreiner R, Schwider J. Testing of rod objects by grazing-incidence interferometry: experiment. Appl Opt. 1999 Jan 01;38(1):121-5. doi: 10.1364/ao.38.000121. PMID: 18305594.
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Design of computer-generated beam-shaping holograms by iterative finite-element mesh adaption.

Applied optics

Dresel T, Beyerlein M, Schwider J.
PMID: 21151284
Appl Opt. 1996 Dec 10;35(35):6865-74. doi: 10.1364/AO.35.006865.

Computer-generated phase-only holograms can be used for laser beam shaping, i.e., for focusing a given aperture with intensity and phase distributions into a pregiven intensity pattern in their focal planes. A numerical approach based on iterative finite-element mesh adaption...

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Dresel T, Beyerlein M, Schwider J. Design of computer-generated beam-shaping holograms by iterative finite-element mesh adaption. Appl Opt. 1996;35(35):6865-74doi: 10.1364/AO.35.006865.
Dresel, T., Beyerlein, M., & Schwider, J. (1996). Design of computer-generated beam-shaping holograms by iterative finite-element mesh adaption. Applied optics, 35(35), 6865-74. https://doi.org/10.1364/AO.35.006865
Dresel, T, et al. "Design of computer-generated beam-shaping holograms by iterative finite-element mesh adaption." Applied optics vol. 35,35 (1996): 6865-74. doi: https://doi.org/10.1364/AO.35.006865
Dresel T, Beyerlein M, Schwider J. Design of computer-generated beam-shaping holograms by iterative finite-element mesh adaption. Appl Opt. 1996 Dec 10;35(35):6865-74. doi: 10.1364/AO.35.006865. PMID: 21151284.
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Combining Engineered U1 snRNA and Antisense Oligonucleotides to Improve the Treatment of a BBS1 Splice Site Mutation.

Molecular therapy. Nucleic acids

Breuel S, Vorm M, Bräuer AU, Owczarek-Lipska M, Neidhardt J.
PMID: 31541798
Mol Ther Nucleic Acids. 2019 Dec 06;18:123-130. doi: 10.1016/j.omtn.2019.08.014. Epub 2019 Aug 16.

Manipulation of pre-mRNA processing is a promising approach toward overcoming disease-causing mutations and treating human diseases. We show that a combined treatment applying two splice-manipulating technologies improves therapeutic efficacies to correct mutation-induced splice defects. Previously, we identified a family...

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Breuel S, Vorm M, Bräuer AU, et al. Combining Engineered U1 snRNA and Antisense Oligonucleotides to Improve the Treatment of a BBS1 Splice Site Mutation. Mol Ther Nucleic Acids. 2019;18:123-130doi: 10.1016/j.omtn.2019.08.014.
Breuel, S., Vorm, M., Bräuer, A. U., Owczarek-Lipska, M., & Neidhardt, J. (2019). Combining Engineered U1 snRNA and Antisense Oligonucleotides to Improve the Treatment of a BBS1 Splice Site Mutation. Molecular therapy. Nucleic acids, 18123-130. https://doi.org/10.1016/j.omtn.2019.08.014
Breuel, Saskia, et al. "Combining Engineered U1 snRNA and Antisense Oligonucleotides to Improve the Treatment of a BBS1 Splice Site Mutation." Molecular therapy. Nucleic acids vol. 18 (2019): 123-130. doi: https://doi.org/10.1016/j.omtn.2019.08.014
Breuel S, Vorm M, Bräuer AU, Owczarek-Lipska M, Neidhardt J. Combining Engineered U1 snRNA and Antisense Oligonucleotides to Improve the Treatment of a BBS1 Splice Site Mutation. Mol Ther Nucleic Acids. 2019 Dec 06;18:123-130. doi: 10.1016/j.omtn.2019.08.014. Epub 2019 Aug 16. PMID: 31541798; PMCID: PMC6796732.
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Paucimannosidic glycoepitopes inhibit tumorigenic processes in glioblastoma multiforme.

Oncotarget

Becker Y, Förster S, Gielen GH, Loke I, Thaysen-Andersen M, Laurini C, Wehrand K, Pietsch T, Diestel S.
PMID: 31320997
Oncotarget. 2019 Jul 09;10(43):4449-4465. doi: 10.18632/oncotarget.27056. eCollection 2019 Jul 09.

Glioblastoma multiforme is an aggressive cancer type with poor patient outcomes. Interestingly, we reported previously a novel association between the little studied paucimannosidic

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Becker Y, Förster S, Gielen GH, et al. Paucimannosidic glycoepitopes inhibit tumorigenic processes in glioblastoma multiforme. Oncotarget. 2019;10(43):4449-4465doi: 10.18632/oncotarget.27056.
Becker, Y., Förster, S., Gielen, G. H., Loke, I., Thaysen-Andersen, M., Laurini, C., Wehrand, K., Pietsch, T., & Diestel, S. (2019). Paucimannosidic glycoepitopes inhibit tumorigenic processes in glioblastoma multiforme. Oncotarget, 10(43), 4449-4465. https://doi.org/10.18632/oncotarget.27056
Becker, Yvonne, et al. "Paucimannosidic glycoepitopes inhibit tumorigenic processes in glioblastoma multiforme." Oncotarget vol. 10,43 (2019): 4449-4465. doi: https://doi.org/10.18632/oncotarget.27056
Becker Y, Förster S, Gielen GH, Loke I, Thaysen-Andersen M, Laurini C, Wehrand K, Pietsch T, Diestel S. Paucimannosidic glycoepitopes inhibit tumorigenic processes in glioblastoma multiforme. Oncotarget. 2019 Jul 09;10(43):4449-4465. doi: 10.18632/oncotarget.27056. eCollection 2019 Jul 09. PMID: 31320997; PMCID: PMC6633888.
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Showing 1 to 12 of 99 entries