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Showing 1 to 12 of 102 entries
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Novel Preclinical and Radiopharmaceutical Aspects of [68Ga]Ga-PSMA-HBED-CC: A New PET Tracer for Imaging of Prostate Cancer.

Pharmaceuticals (Basel, Switzerland)

Eder M, Neels O, Müller M, Bauder-Wüst U, Remde Y, Schäfer M, Hennrich U, Eisenhut M, Afshar-Oromieh A, Haberkorn U, Kopka K.
PMID: 24983957
Pharmaceuticals (Basel). 2014 Jun 30;7(7):779-96. doi: 10.3390/ph7070779.

The detection of prostate cancer lesions by PET imaging of the prostate-specific membrane antigen (PSMA) has gained highest clinical impact during the last years. 68Ga-labelled Glu-urea-Lys(Ahx)-HBED-CC ([68Ga]Ga-PSMA-HBED-CC) represents a successful novel PSMA inhibitor radiotracer which has recently demonstrated its...

The role of protease-activated receptors in regulating other ion channels.

Annals of gastroenterology

Eisenhut M.
PMID: 25330914
Ann Gastroenterol. 2014;27(4):429.

No abstract available.

Determination of boron isotopic variations in aquatic systems with negative thermal ionization mass spectrometry as a tracer for anthropogenic influences.

Analytical and bioanalytical chemistry

Eisenhut S, Heumann KG, Vengosh A.
PMID: 15048414
Anal Bioanal Chem. 1996 Mar;354(7):903-9. doi: 10.1007/s0021663540903.

A technique for precise boron isotope ratio measurements with a high detection power has been developed by negative thermal ionization mass spectrometry (NTIMS). Relative standard deviations in the range of 0.03-0.3% have been obtained for the determination of the...

Characteristic abnormalities in cerebrospinal fluid biochemistry in children with cerebral malaria compared to viral encephalitis.

Cerebrospinal fluid research

Jakka SR, Veena S, Atmakuri RM, Eisenhut M.
PMID: 16764711
Cerebrospinal Fluid Res. 2006 Jun 09;3:8. doi: 10.1186/1743-8454-3-8.

BACKGROUND: In developing countries where Plasmodium falciparum malaria is endemic, viral encephalitis and cerebral malaria are found in the same population, and parasitemia with Plasmodium falciparum is common in asymptomatic children. The objective of this study was to investigate...

On-surface synthesis of nitrogen-doped nanographenes with 5-7 membered rings.

Chemical communications (Cambridge, England)

Skidin D, Eisenhut F, Richter M, Nikipar S, Krüger J, Ryndyk DA, Berger R, Cuniberti G, Feng X, Moresco F.
PMID: 30942792
Chem Commun (Camb). 2019 Apr 16;55(32):4731-4734. doi: 10.1039/c9cc00276f.

We report on the formation of nitrogen-doped nanographenes containing five- and seven-membered rings by thermally induced cyclodehydrogenation on the Au(111) surface. Using scanning tunneling microscopy and supported by calculations, we investigated the structure of the precursor and targets, as...

Tuning the conductance of a molecular wire by the interplay of donor and acceptor units.

Nanoscale

Skidin D, Erdmann T, Nikipar S, Eisenhut F, Krüger J, Günther F, Gemming S, Kiriy A, Voit B, Ryndyk DA, Joachim C, Moresco F, Cuniberti G.
PMID: 30182095
Nanoscale. 2018 Sep 20;10(36):17131-17139. doi: 10.1039/c8nr05031g.

We investigate the conductance of optimized donor-acceptor-donor molecular wires obtained by on-surface synthesis on the Au(111) surface. A careful balance between acceptors and donors is achieved using a diketopyrrolopyrrole acceptor and two thiophene donors per unit along the wire....

Commentary: Cytokine-Regulation of Na.

Frontiers in immunology

Eisenhut M.
PMID: 29163549
Front Immunol. 2017 Nov 06;8:1490. doi: 10.3389/fimmu.2017.01490. eCollection 2017.

No abstract available.

Endogenous Na/K ATPase inhibitor ouabain in critically ill children with lung injury.

Pathophysiology : the official journal of the International Society for Pathophysiology

Eisenhut M, Leppäluoto J.
PMID: 21414760
Pathophysiology. 2011 Jun;18(3):243-5. doi: 10.1016/j.pathophys.2011.02.002. Epub 2011 Mar 17.

OBJECTIVES: To measure ouabain, an endogenous adrenocortical Na/K ATPase inhibitor, in critically ill children with acute lung injury and relate it to parameters reflecting epithelial sodium transport.DESIGN: Prospective observational study.SETTING: Paediatric Intensive Care Unit of Royal Liverpool Children's Hospital.SUBJECTS:...

Neurodisability with Severe Restriction of Mobility Is Associated with Reduced Serum Creatinine Values.

International journal of pediatrics

Lim C, Phillips M, Watson L, Eisenhut M.
PMID: 31316567
Int J Pediatr. 2019 Jun 16;2019:3598123. doi: 10.1155/2019/3598123. eCollection 2019.

INTRODUCTION: We investigated whether reduced mobility is associated with a reduction in serum creatinine in otherwise well children with neurodisability.MATERIALS AND METHODS: This was a record based retrospective study and creatinine levels of children in groups with Gross Motor...

Directed evolution approach to enhance efficiency and speed of outgrowth during single cell subcloning of Chinese Hamster Ovary cells.

Computational and structural biotechnology journal

Weinguny M, Klanert G, Eisenhut P, Jonsson A, Ivansson D, Lövgren A, Borth N.
PMID: 32612755
Comput Struct Biotechnol J. 2020 Jun 02;18:1320-1329. doi: 10.1016/j.csbj.2020.05.020. eCollection 2020.

Chinese Hamster Ovary (CHO) cells are the working horse of the pharmaceutical industry. To obtain high producing cell clones and to satisfy regulatory requirements single cell cloning is a necessary step in cell line development. However, it is also...

Efficacy of Cancer Immunotherapy: An Umbrella Review of Meta-analyses of Randomized Controlled Trials.

Cancers

Kim JY, Lee KH, Eisenhut M, van der Vliet HJ, Kronbichler A, Jeong GH, Shin JI, Gamerith G.
PMID: 31731818
Cancers (Basel). 2019 Nov 15;11(11). doi: 10.3390/cancers11111801.

We conducted a systematic review for evidence of the clinical efficacy of cancer immunotherapies. We searched PubMed from inception to 14 February 2018 for meta-analyses of randomized controlled trials (RCTs) of cancer immunotherapies. Re-analyses were performed to estimate the...

Hexacene generated on passivated silicon.

Nanoscale

Eisenhut F, Krüger J, Skidin D, Nikipar S, Alonso JM, Guitián E, Pérez D, Ryndyk DA, Peña D, Moresco F, Cuniberti G.
PMID: 29938293
Nanoscale. 2018 Jul 09;10(26):12582-12587. doi: 10.1039/c8nr03422b.

On-surface synthesis represents a successful strategy to obtain designed molecular structures on an ultra-clean metal substrate. While metal surfaces are known to favor adsorption, diffusion, and chemical bonding between molecular groups, on-surface synthesis on non-metallic substrates would allow the...

Showing 1 to 12 of 102 entries