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Showing 1 to 6 of 6 entries
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Dietary Supplementation of Calendula officinalis Counteracts the Oxidative Stress and Liver Damage Resulted from Aflatoxin.

ISRN nutrition

Hamzawy MA, El-Denshary ES, Hassan NS, Mannaa FA, Abdel-Wahhab MA.
PMID: 24959547
ISRN Nutr. 2013 Feb 12;2013:538427. doi: 10.5402/2013/538427. eCollection 2013.

This study was conducted to evaluate the total phenolic compounds, the antioxidant properties, and the hepatorenoprotective potential of Calendula officinalis extract against aflatoxins (AFs-) induced liver damage. Six groups of male Sprague-Dawley rats were treated for 6 weeks included...

Ameliorative effects of thyme and calendula extracts alone or in combination against aflatoxins-induced oxidative stress and genotoxicity in rat liver.

Cytotechnology

Abdel-Aziem SH, Hassan AM, El-Denshary ES, Hamzawy MA, Mannaa FA, Abdel-Wahhab MA.
PMID: 24096837
Cytotechnology. 2014 May;66(3):457-70. doi: 10.1007/s10616-013-9598-7. Epub 2013 Oct 06.

The aims of the current work were to evaluate the hepatoprotective effect of calendula flowers and/or thyme leave extracts on aflatoxins (AFs)-induced oxidative stress, genotoxicity and alteration of p53 bax and bcl2 gene expressions. Eighty male Sprague-Dawley rats were...

Isoflavones-Enriched Soy Protein Prevents CCL(4)-Induced Hepatotoxicity in Rats.

ISRN pharmacology

Sarhan NA, El-Denshary ES, Hassan NS, Abu-Salem FM, Abdel-Wahhab MA.
PMID: 22530140
ISRN Pharmacol. 2012;2012:347930. doi: 10.5402/2012/347930. Epub 2012 Mar 01.

The burden of liver disease in Egypt is exceptionally high due to the highest prevalence of hepatitis C virus (HCV) resulting in rising rates of hepatocellular carcinoma (HCC). The aim of the current study was to determine the isoflavones...

Paroxetine ameliorates changes in hippocampal energy metabolism in chronic mild stress-exposed rats.

Neuropsychiatric disease and treatment

Khedr LH, Nassar NN, El-Denshary ES, Abdel-Tawab AM.
PMID: 26622178
Neuropsychiatr Dis Treat. 2015 Nov 13;11:2887-901. doi: 10.2147/NDT.S87089. eCollection 2015.

The molecular mechanisms underlying stress-induced depression have not been fully outlined. Hence, the current study aimed at testing the link between behavioral changes in chronic mild stress (CMS) model and changes in hippocampal energy metabolism and the role of...

Enhanced efficacy and reduced side effects of diazepam by kava combination.

Journal of advanced research

Tawfiq RA, Nassar NN, El-Eraky WI, El-Denshary ES.
PMID: 25685527
J Adv Res. 2014 Sep;5(5):587-94. doi: 10.1016/j.jare.2013.08.002. Epub 2013 Aug 22.

The long term use of antiepileptic drugs possesses many unwanted effects; thus, new safe combinations are urgently mandated. Hence, the present study aimed to investigate the anticonvulsant effect of kava alone or in combination with a synthetic anticonvulsant drug,...

Bee venom attenuates neurodegeneration and motor impairment and modulates the response to L-dopa or rasagiline in a mice model of Parkinson's disease.

Iranian journal of basic medical sciences

Badawi HM, Abdelsalam RM, Abdel-Salam OM, Youness ER, Shaffie NM, Eldenshary EDS.
PMID: 33489038
Iran J Basic Med Sci. 2020 Dec;23(12):1628-1638. doi: 10.22038/ijbms.2020.46469.10731.

OBJECTIVES: This study aimed to investigate the effect of bee venom, a form of alternative therapy, on rotenone-induced Parkinson's disease (PD) in mice. Moreover, the possible modulation by bee venom of the effect of L-dopa/carbidopa or rasagiline was examined.MATERIALS...

Showing 1 to 6 of 6 entries