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Showing 1 to 12 of 40 entries
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Antiproliferative, Apoptotic Effects and Suppression of Oxidative Stress of Quercetin against Induced Toxicity in Lung Cancer Cells of Rats: .

Journal of Cancer

Zhaorigetu, Farrag IM, Belal A, Badawi MHA, Abdelhady AA, Galala FMAA, El-Sharkawy A, El-Dahshan AA, Mehany ABM.
PMID: 34335941
J Cancer. 2021 Jun 26;12(17):5249-5259. doi: 10.7150/jca.52088. eCollection 2021.

In the present study, quercetin was examined against lung human cancer cells using A549 and H69 cancer cell lines in addition to normal non cancer cells (W138). Two genes Bax and Bcl-2 that play an important role in apoptosis...

Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury.

Experimental neurology

Fouda AY, Eldahshan W, Xu Z, Lemtalsi T, Shosha E, Zaidi SA, Abdelrahman AA, Cheng PN, Narayanan SP, Caldwell RW, Caldwell RB.
PMID: 34780773
Exp Neurol. 2022 Feb;348:113923. doi: 10.1016/j.expneurol.2021.113923. Epub 2021 Nov 12.

Arginase 1 (A1) is the enzyme that hydrolyzes the amino acid, L-arginine, to ornithine and urea. We have previously shown that A1 deletion worsens retinal ischemic injury, suggesting a protective role of A1. In this translational study, we aimed...

Baicalein 5,6-Dimethyl Ether Prevents Memory Deficits in the Scopolamine Zebrafish Model by Regulating Cholinergic and Antioxidant Systems.

Plants (Basel, Switzerland)

Brinza I, Ayoub IM, Eldahshan OA, Hritcu L.
PMID: 34207381
Plants (Basel). 2021 Jun 18;10(6). doi: 10.3390/plants10061245.

Baicalein 5,6-dimethyl ether, a bioactive flavonoid isolated for the first time from

Insights on the Inhibitory Power of Flavonoids on Tyrosinase Activity: A Survey from 2016 to 2021.

Molecules (Basel, Switzerland)

El-Nashar HAS, El-Din MIG, Hritcu L, Eldahshan OA.
PMID: 34946631
Molecules. 2021 Dec 13;26(24). doi: 10.3390/molecules26247546.

Tyrosinase is a multifunctional copper-containing oxidase enzyme that initiates melanin synthesis in humans. Excessive accumulation of melanin pigments or the overexpression of tyrosinase may result in skin-related disorders such as aging spots, wrinkles, melasma, freckles, lentigo, ephelides, nevus, browning...

Evidence-based complementary and alternative medicine : eCAM

Todirascu-Ciornea E, El-Nashar HAS, Mostafa NM, Eldahshan OA, Boiangiu RS, Dumitru G, Hritcu L, Singab ANB.
PMID: 31885652
Evid Based Complement Alternat Med. 2019 Dec 02;2019:5256781. doi: 10.1155/2019/5256781. eCollection 2019.

No abstract available.

Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury.

Experimental neurology

Fouda AY, Eldahshan W, Xu Z, Lemtalsi T, Shosha E, Zaidi SA, Abdelrahman AA, Cheng PN, Narayanan SP, Caldwell RW, Caldwell RB.
PMID: 34780773
Exp Neurol. 2021 Nov 12;348:113923. doi: 10.1016/j.expneurol.2021.113923. Epub 2021 Nov 12.

Arginase 1 (A1) is the enzyme that hydrolyzes the amino acid, L-arginine, to ornithine and urea. We have previously shown that A1 deletion worsens retinal ischemic injury, suggesting a protective role of A1. In this translational study, we aimed...

Orange fruit (.

Food & function

Abdelghffar EA, El-Nashar HAS, Al-Mohammadi AGA, Eldahshan OA.
PMID: 34606555
Food Funct. 2021 Oct 04;12(19):9443-9455. doi: 10.1039/d1fo01905h.

No abstract available.

Upregulation of Twist2 in Non-Muscle Invasive Urothelial Carcinoma of the Bladder Correlate with Response to Treatment and Progression.

Open access Macedonian journal of medical sciences

Wishahi M, Khalil H, Badawy MH, Elkholy A, Eseily K, Anis S, Eldahshan S, Kamel N, Romeih M.
PMID: 29983794
Open Access Maced J Med Sci. 2018 Jun 05;6(6):1017-1022. doi: 10.3889/oamjms.2018.165. eCollection 2018 Jun 20.

BACKGROUND: Twist2 is a transcription factor and an epithelial-to-mesenchymal transition that plays an important role in cell polarity, cell adhesion, and has a role in tumour invasion and metastases.AIM: In this study, we examined the expression of Twist2 in...

Chemical composition, antimicrobial and cytotoxic activities of essential oils from .

Natural product research

El-Nashar HAS, Mostafa NM, El-Badry MA, Eldahshan OA, Singab ANB.
PMID: 32441134
Nat Prod Res. 2021 Dec;35(23):5369-5372. doi: 10.1080/14786419.2020.1765343. Epub 2020 May 22.

No abstract available.

Genital-Sparing Cystectomy versus Standard Urethral-Sparing Cystectomy Followed with Orthotopic Neobladder in Women with Bladder Cancer: Incidence and Causes of Hypercontinence with an Ultrastructure Study of Urethral Smooth Muscles.

Open access Macedonian journal of medical sciences

Wishahi M, Ismail MA, Elganzoury H, Elkholy A, Nour HH, Zayed AS, Eldahshan S.
PMID: 30976344
Open Access Maced J Med Sci. 2019 Mar 27;7(6):978-981. doi: 10.3889/oamjms.2019.206. eCollection 2019 Mar 30.

BACKGROUND: Bladder cancer in women is an indication for radical cystectomy (RC) when the tumour is confined muscle-invasive bladder cancer (MIBC) of T2 N0M0, or high risk progressive non-muscle invasive bladder cancer (NMIBC). Radical cystectomy is either genital-sparing cystectomy...

Deepfake video detection: YOLO-Face convolution recurrent approach.

PeerJ. Computer science

Ismail A, Elpeltagy M, Zaki M, ElDahshan KA.
PMID: 34712799
PeerJ Comput Sci. 2021 Sep 21;7:e730. doi: 10.7717/peerj-cs.730. eCollection 2021.

Recently, the deepfake techniques for swapping faces have been spreading, allowing easy creation of hyper-realistic fake videos. Detecting the authenticity of a video has become increasingly critical because of the potential negative impact on the world. Here, a new...

Reverse engineering approach for improving the quality of mobile applications.

PeerJ. Computer science

Elsayed EK, ElDahshan KA, El-Sharawy EE, Ghannam NE.
PMID: 33816865
PeerJ Comput Sci. 2019 Aug 19;5:e212. doi: 10.7717/peerj-cs.212. eCollection 2019.

BACKGROUND: Portable-devices applications (Android applications) are becoming complex software systems that must be developed quickly and continuously evolved to fit new user requirements and execution contexts. Applications must be produced rapidly and advance persistently in order to fit new...

Showing 1 to 12 of 40 entries